Chapter One: The Human Body M.C. Shamier, MD Shenzhou University Subjects Anatomy Anatomy defined The language of anatomy Physiology Physiology defined Levels of organization Homeostasis Anatomy Greek: ἀνατέμνειν “to cut open” tonsillec-tomy: cutting away the tonsils of the throat. The study of the structure of living things Michiel van Mierevelt, 1617 Subdivisions Gross or macroscopic anatomy Microscopic anatomy Histology Cytology Developmental anatomy and embryology Radiographic anatomy Pathological anatomy Histology and cytology Radiographic and pathological anatomy The language of anatomy Anatomical position Directional terms Regional names Body planes Abdominopelvic regions Body cavities Arbitrary Physiologic The language of anatomy Anatomical position Directional terms Directional terms Directional terms Directional terms Directional terms Regional names Body planes Abdominopelvic regions Body cavities “Body cavities are spaces within the body that are closed to the outside and contain the internal organs.” Body cavities Example: cranial and spinal cavity Together one continuous space, home to the central nervous system (CNS) Confined by bone: skull and vertebral column Filled with cerebrospinal fluid Are there any questions? Next: Physiology Physiology Greek: Φύσις: “nature -λογία: “the study of” The science of the functioning of living things. Inseperately connected to anatomy: function reflects shape Levels of structural organization Question: What is the smallest unit that the body is essentially composed of? Levels of structural organization Question Could you think of a seventh level? The seventh level: environmental context Hendrick Avercamp New York City And the environment also contains: Yellow fever Organism and environment The organism is subject to: Climate Microbes Social interaction Air pressure And dependent on the environment for: Oxygen Nutrients Water Boundaries Question: What seperates the organism from its environment? ‘Milieu intérieur’ and ‘milieu extérieur’ “The fixity of the milieu supposes a perfection of the organism such that the external variations are at each instant compensated for and equilibrated. All of the vital mechanisms, however varied they may be, have always one goal, to maintain the uniformity of the conditions of life in the internal environment.The stability of the internal environment is the condition for the free and independent life.” Claude Bernard, French Physiologist, 1854: Example: Temperature Question What is the baseline temperature of the human body? Question What happens when the environmental temperature drops? Example: Temperature This is called: Homeostasis Homeostasis: The ability of the body to maintain a relatively constant internal environment, regardless of environmental changes. How does it work? The mechanism of negative feedback: failure leads to imbalance which means disease. Concluded There are several levels of structural organization within an organism: from the atom to the organism (living in an environment). All vital systems work together to maintain a stable internal environment, compensating for external variations. The mechanism is negative feedback. This is called homeostasis. End of Chapter One