Anatomy Introduction to Clinically Oriented Anatomy Associate Professor Dr. Alexey Podcheko Spring 2015 Approaches to Studying Anatomy Anatomy is the study of the structure of the human body. Regional anatomy considers the body as organized into segments or parts; systemic anatomy sees the body as organized into organ systems. Surface anatomy provides information about structures that may be observed or palpated beneath the skin, radiographic anatomy allows appreciation of structures in the living, as they are affected by muscle tone, body fluids and pressures, and gravity. Clinical anatomy emphasizes application knowledge to the practice of medicine. 2 of anatomical ADMINISTRATION Course Director: Dr. Alexey Podcheko MD, Ph.D, Associate Professor Email: apodcheko@mail.sjsm.org Course Instructor: Dr. Ermanul Huq Ph.D; Assistant Professor Email: ehuq@mail.sjsm.org My background 1989-1995 – MD (General Practitioner) from Smolensk State School of Medicine, Russia 1995-1998 – Residency at Departments of Pathology and Clinical Endocrinology of Smolensk State Medical School 1998-2000- Assistant Professor at Department of Clinical Endocrinology 2000-2005 - Ph.D. in Molecular Biology at Nagasaki University, School of Medicine, (Japan) 2005-2010 – Postdoctoral Research Associate at Department of Laboratory Medicine and Pathobiology, University of Toronto, School of Medicine 2010- Associate Professor at Department of Basic Sciences SJSM Research Projects: Ionizing Radiation and Thyroid Cancer -To clarify the mechanisms of radiationinduced thyroid carcinogenesis -To develop novel diagnostic techniques and gene/molecular-targeted therapy for thyroid cancer -To analyze genomic instability in multistep process of radiation carcinogenesis -To analyze radiation-induced cellular and molecular response -To identify the molecular mechanisms of cellular senescence and stress response -To clarify the mechanisms of UV or ionizing radiation-induced DNA damage repair May the tree thrive. My research in Diabetes area •Role of immunomodulators (thymic extracts) on protection against experimental Type I Diabetes •Identification of novel genes involved in beta-cell growth and survival •Cloning and characterization of novel positive regulator of betacell growth - Plekstrin Homology Interacting Protein 1 (PHIP1) My research/publications: TEXTBOOKS You will need for the course: Clinically Oriented Anatomy by Keith L. Moore et al., Lippincott Williams & Wilkins, 2010 BRS Gross Anatomy, 6 or 7th edition by Kyung W. Chung. Published by Lippincott Williams & Wilkins, Atlas of Human Anatomy, 4th edition by Frank H. Netter. Published by Saunders, 2006 or an equivalent atlas will be acceptable Other resources: Acland’s Video Atlas of Human Anatomy http://aclandanatomy.com/index.aspx Anatomyzone http://anatomyzone.com/ Anatomy Mnemonics http://www.medicalmnemonics.com/cgibin/browse.cfm https://itunes.apple.com/us/app/anatomymnemonicsmusculoskeletal/id863837276?mt=8 Dissection Lab manual needed for the course: Gray's Dissection Guide for Human Anatomy: With STUDENT CONSULT Online Access, 2e Or Grant's Dissector (Tank, Grant's Dissector) ON LINE RESOURCES http://www.visiblebody.com/ http://www.med.umich.edu/lrc/coursepages/ m1/anatomy2010/html/index.html http://www.wesnorman.com (Georgetown University’s anatomist, Wes Norman, has his own site with images, information and quizzes) AnatomyOne http://www.anatomyone.com/ http://medicalppt.blogspot.com/search/label /ANATOMY Question Banks BRS Gross Anatomy, 7th edition by Kyung W. Chung. Published by Lippincott Williams & Wilkins Appleton & Lange Review of Anatomy, Sixth Edition, Royce Lee Montgomery, PhD USMLE Easy (sjsm.org/library) Other important qBanks: USMLE WORLD USMLE-RX ATTENDANCE POLICY Students must attend at least 80% of lectures. Attendance will be monitored through Moodle or by a roll call Any student falling short of 80% attendance please refer to the Attendance policy of SJSM Anguilla campus Organization of Course ~12 weeks ~ 60 Lectures (5 times/week) Laboratory Classes 2 times per week starting from next week Major Topics: -Introduction to the Anatomy course -Back -Thorax -Upper Limb -Abdomen -Pelvis -Lower Limb -Head and Neck Student must read/review appropriate textbook chapter before the lecture EVALUATIONS The course is divided on 4 blocks Every block (app. 3 weeks of classes) you will be evaluated in the 1. 2. following ways: Attendance for lectures and lab classes : if you missed >20% of lectures or labs for first time without providing approved Leave of Absence/doctor/legal note, 20 points will deducted from your final block score (second time you did it – will get 0 for the block). 1 written 25 MCQs quiz per block (dates of quizzes are in the syllabus) will provide up to 10 bonus points to final block score 1 written 50 MCQs block exam – will provide 80% of your block score 1 practical exam (identification of specific structures on cadavers, bones, X-Ray films, etc) – will provide 20% of your final score Final course score and grade will be calculated based on the following formula: Final course score=(B1+B2+B3+B4)/4; B1-4=Block 1-4 scores EVALUATIONS Example of score calculation for student A: Student A attended 100% of all classes Student A answered 60% of Quiz questions correctly – received 6 points Student A on the Written exam answered 70% of questions correctly – received 70*0.8=56 points Student A on the Practical exam answered 80% of questions correctly – received 0.2*80=16 points Final score of the student for Block 1 is : 6+56+16=78 (C) All grades will be posted on Moodle within 1 week after quiz/exam EVALUATIONS Curving: Curving will be done only for 50 questions MCQ exam in case if average of the group is below 70. The aim of the curving is to bring average score of the group to the range of 70 by using the following formula: Curved Score=100-A(100-You Raw Score); A could be between 0-1. Laboratory Classes SJSM ANATOMY Lab Policies posted on the Moodle No photos/video in the lab due to ethical issues Cadavers should be appropriately draped at all times. Shorts, short skirts, sandals, and open-toe and heel shoes are not allowed: this lab employs chemical and biological agents Wear lab coats and scrubs. After the end of each session, leave them in the lab or take home in a plastic bag for laundry. Students not in compliance with the lab dress code or other safety regulations will not enter the lab Laboratory Classes You are only allowed to dissect the cadaver you have been assigned to. The cadavers MUST be kept moist. Every time you open a cadaver bag, spray it generously with the wetting fluid before closing the bag. INTENDED LEARNING OUTCOMES FOR ANATOMY COURSE Knowledge and understanding of the principles of Evidence Based Medicine. Knowledge and understanding of normal structure and function of the body and each of its major organ systems. The ability to perform routine technical dissection procedures specic to the medical speciality. Perform practical exercises that entail accurate observation of biomedical phenomenon and critical analyses of data. The ability to apply Evidence Based Medicine principles to clinical decision making The ability to seek help, when needed, to deal with academic, personal, or interpersonal problems. Clinical vignettes and Anatomy Why do we need them? A 47-year-old man is brought to the emergency department after being involved in a motor vehicle accident. He was a restrained driver and rear-ended a slowly moving car on a highway. He complains of chest pain, abdominal pain, and shortness of breath. His other medical problems include hypertension, asthma, and type 2 diabetes mellitus. His initial blood pressure is 90/54 mm Hg and pulse is 121/min. He becomes unresponsive and loses his pulse 30 minutes after arriving at the hospital. His EKG monitoring demonstrates sinus tachycardia. The patent dies despite resuscitation efforts. Which of the following identifiers from the figure indicates the site most likely to have an aortic injury on autopsy? A. A B. B C. C D. D Explanation This patient presents after trauma with signs/symptoms consistent with likely aortic rupture, which is most commonly caused by motor vehicle accidents. A motor vehicle accident with sudden deceleration can cause different rates of deceleration between the heart (in a fixed position) and the aorta . The most common site of injury is the aortic isthmus (site C on the figure), which is the connection between the ascending and descending aorta distal to where the left subclavian artery branches off the aorta Patients typically present with chest pain, back pain, or shortness of breath. However, there can be significant rupture, causing instant death after the trauma Patients who survive the initial rupture may have a widened mediastinum on chest x-ray. Approaches to Studying Anatomy 1. Regional Anatomy Regional anatomy (topographical anatomy) considers the Thorax organization of the human body as segments or major parts based on Abdomen form and mass Upper Limb a main body, consisting of the head, neck, Pelvis/Perineum trunk (subdivided into thorax, abdomen, back, Lower Limb and pelvis/perineum), paired upper limbs and lower limbs. 26 Head Neck Back Approaches to Studying Anatomy 2. Systemic Anatomy Systemic anatomy recognizes the organization of the body's organs into systems or collective apparatuses that work together to carry out complex functions The 27 integumentary system (dermatology) consists of the skin (L. integumentum, a covering) and its appendages hair, nails, and sweat glands The skeletal system (osteology) consists of bones and cartilage The articular system (arthrology) consists of joints and their associated ligaments The muscular system (myology) The nervous system (neurology) consists of the central nervous system (brain and spinal cord) and the peripheral nervous system The circulatory system (angiology) consists of the cardiovascular and lymphatic systems The digestive or alimentary system (gastroenterology) The respiratory system (pulmonology) The urinary system (urology) consists of the kidneys, ureters, urinary bladder, and urethra The reproductive or genital system (gynecology for females; andrology for males) consists of the gonads (ovaries and testes) The endocrine system (endocrinology) Approaches to Studying Anatomy 3. Clinical Anatomy Clinical (applied) anatomy emphasizes aspects of bodily structure and function important in the practice of medicine, dentistry, and the allied health sciences. It incorporates the regional and systemic approaches to studying anatomy and stresses clinical application. Clinical anatomy often involves inverting or reversing the thought process typically followed when studying regional or systemic anatomy. For example, The action of this muscle is …? clinical anatomy asks, How would the absence of this muscle's activity be manifest? The nerve provides innervation to this area of skin, clinical anatomy asks, Numbness in this area indicates a lesion of which nerve? 28 Anatomical Position The anatomical position refers to the body position as if the person were standing upright, regardless of the actual posture or position, with the: 1. 2. 3. 29 Head, gaze (eyes), and toes anteriorly (forward). Arms adjacent to the sides palms facing anteriorly. Lower limbs close together feet parallel and the toes anteriorly. directed with the with the directed Anatomical Planes Anatomical descriptions are based on four imaginary planes (median, sagittal, frontal, and transverse) that intersect the body in the anatomical position 1. 30 The median plane, the vertical plane passing longitudinally through the body, divides the body into right and left halves. The plane intersects the midlines of the anterior and posterior surfaces of the body Anatomical Planes 2. Sagittal planes are vertical planes passing through the body parallel to the median plane. It is helpful to give a point of reference by naming a structure intersected by the plane you are referring to, such as a sagittal plane through the midpoint of the clavicle. The term midsagittal plane is a superfluous term for the median plane Parasagittal, commonly used by neuroanatomists and neurologists, is also unnecessary because any plane parallel and to either side of the median plane is sagittal by definition. However, a plane parallel and near to the median plane may be referred to as a paramedian plane. 31 Anatomical Planes 3. Frontal (coronal) planes are vertical planes passing through the body at right angles to the median plane, dividing the body into anterior (front) and posterior (back) parts. Again, a point of reference is necessary to indicate the position of the plane (e.g., a frontal plane through the heads of the mandible). 32 Anatomical Planes 4. Transverse planes are planes passing through the body at right angles to the median and frontal planes, dividing the body into superior (upper) and inferior (lower) parts. It is helpful to give a reference point to identify the level of the plane, such as a transverse plane through the umbilicus or through a specific vertebra. Radiologists refer to transverse planes as transaxial, commonly shortened planes. 33 which is to axial Anatomical Planes The number of sagittal, frontal, and transverse planes is unlimited. The main use of anatomical planes is to describe sections. Sections provide views of the body as if cut or sectioned along particular planes. Longitudinal sections run lengthwise or parallel to the long axis of the body or of any of its parts, and the term applies regardless of the position of the body. 34 Anatomical Planes Transverse sections, or cross sections, are slices of the body or its parts that are cut at right angles to the longitudinal axis of the body or of any of its parts; Q: Transverse Section of the foot lies in Frontal ____________ Plane. Note: the long axis of the foot runs horizontally, a transverse section of the foot lies in the frontal plane . Oblique sections are slices of the body or any of its parts that are not cut along one of the previously mentioned anatomical planes. 35 Terms of Relationship and Comparison Superficial, intermediate, and deep describe the position of structures relative to the surface of the body or the relationship of one structure to another underlying or overlying structure. Superficial: Toward the surface Example: The muscles of the arm are superficial to its bone (Humerus) Intermediate: Between Deep structure a Superficial and Example: The biceps muscle is intermediate between the skin and the humerous Deep: Away from the surface of the body 36 Example: The humerus is deep to the arm muscles Terms of Relationship and Comparison Superior refers to a structure that is nearer the vertex, the topmost point of the cranium. Cranial relates to the cranium (skull) and is a useful directional term, meaning toward the head. Example: The Heart is Superior to the stomach Inferior refers to a structure that is 37 situated nearer the sole of the foot. Caudal (L. cauda, tail) is a useful directional term that means toward the tail region, represented in humans by the coccyx, the small bone at the inferior (caudal) end of the vertebral column. The term caudal is used in embryology The stomach is inferior to the heart Terms of Relationship and Comparison Posterior (dorsal) denotes the back surface of the body or nearer to the back. Example: The heal is posterior to the toes 38 Anterior (ventral) denotes the front surface of the body. Rostral is often used instead of anterior when describing parts of the brain; it means toward the rostrum (beak) Example: The toes are anterior to the ankle Terms of Relationship and Comparison Proximal and distal are used when contrasting positions nearer to or farther from the attachment of a limb or the central aspect of a linear structure, respectively. Proximal : Nearer to trunk or point of origin Example: The elbow is proximal to the wrist Distal: Farther from trunk or point of origin Example: The Wrist is distal to the elbow 39 Terms of Relationship and Comparison Medial is used to indicate that (in the anatomical position) a structure, such as the 5th digit of the hand (little finger), is nearer to the median plane of the body than the other digits. lateral stipulates that a structure, such as the 1st digit of the hand (thumb), is farther away from the median plane. *NOTE: Lateral and medial are not synonymous with the terms external (outer) and internal (inner). External and internal mean farther from and nearer to the center of an organ or cavity, respectively, regardless of direction. 40 Median Plane Terms of Movement Flexion indicates bending or decreasing the angle between the bones or parts of the body. ( Blue Arrows) For most joints (e.g., elbow), flexion generally involves movement in an anterior direction; however, flexion at the knee joint involves posterior movement. Dorsiflexion describes flexion at the ankle joint, as occurs when walking uphill or lifting the toes off the ground. Plantarflexion turns the foot or toes toward 41 the plantar surface (e.g., when standing on your toes). Terms of Movement Extension indicates straightening or increasing the angle between the bones or parts of the body. (green Arrows) • Extension usually occurs in a posterior direction (saggital plain) •but extension of the knee joint occurs in an anterior direction. Extension of a limb or part beyond the normal limit hyperextension (overextension) can cause injury, such as whiplash (i.e., hyperextension of the neck during a rear-end automobile collision). !!! For the thumb, from the anatomical position, 42 flexion and extension are movements in the frontal plane Terms of Movement Abduction : moving away from the median plane in the frontal plane (e.g., when moving an upper limb away from the side of the body). In abduction of the digits (fingers or toes), the term means spreading them apart moving the other fingers away from the neutrally positioned 3rd (middle) finger or moving the other toes away from the neutrally positioned 2nd toe. The 3rd finger and 2nd toe medially or laterally abduct away from the neutral position. 43 Right and left lateral flexion (lateral bending) are special forms of abduction for only the neck and trunk. Terms of Movement Adduction means moving toward the median plane in a frontal plane (e.g., when moving an upper limb toward the side of the body). In adduction of the digits, the term means reapproximating the spread fingers or toes or moving the other digits toward the neutral position of the 3rd finger or 2nd toe The medially or laterally abducted 3rd finger or 2nd toe adducts back to the neutral position Note:* The thumb is rotated 90° relative to other structure. Thumb flexes and extends in the frontal plane, and abducts and adducts in 44 the sagittal plane Terms of Movement Circumduction is a circular movement that is a combination of flexion, extension, abduction, and adduction occurring in such a way that the distal end of the part moves in a circle. Circumduction can occur at any joint at which all the abovementioned movements are possible (e.g., the hip joint). Rotation involves turning or revolving a part of the body around its longitudinal axis, such as turning one's head to face sideways. Medial rotation (internal rotation) brings the anterior surface of a limb closer to the median plane, Lateral rotation (external rotation) takes the anterior surface away from the median plane. 45 Terms of Movement Pronation is the rotational movement of the forearm and hand that swings the radius (the lateral long bone of the forearm) medially around its longitudinal axis so that the palm of the hand faces posteriorly and its dorsum faces anteriorly. When the elbow joint is flexed, pronation moves the hand so that the palm faces inferiorly (e.g., placing the palms flat on a table). When applied to the foot, pronation refers to a movement that results in lowering of the medial margin of the foot. (The feet of an individual with flat feet are pronated.) Terms of Movement Supination is the rotational movement of the forearm and hand that swings the radius laterally around its longitudinal axis so that the dorsum of the hand faces posteriorly and the palm faces anteriorly (i.e., moving them into the anatomical position). When the elbow joint is flexed, supination moves the hand so that the palm faces superiorly. When applied to the foot, supination generally implies movements resulting in raising the medial margin of the foot. 47 Mnemonics: "SOUPination": Supination is to turn your arm palm up, as if you are holding a bowl of soup. "POUR-nation": Pronation is to turn your arm with the palm down, as if you are pouring out whatever is your bowl. Think: "Supinate to the Sun and Pronate to the Plants" Supination: palm towards the Sun Pronation: palm towards the Plants Terms of Movement Inversion moves the sole of the foot toward the median plane (facing the sole medially, aka supination). When the foot is fully inverted it is also plantarflexed. Eversion moves the sole of the foot away from the median plane (turning the sole laterally, aka pronation). When the foot is fully everted it is also dorsiflexed 49 Eversion Terms of Movement Opposition is the movement by which the pad of the 1st digit (thumb) is brought to another digit pad. This movement is used to pinch, button a shirt, and lift a teacup by the handle. Reposition describes the movement of the 1st digit from the position of opposition back to its anatomical position. Protrusion is a movement anteriorly (forward) as in protruding the mandible (chin), lips, or tongue. Retrusion is a movement posteriorly (backward), as in retruding the mandible, lips, or tongue. The similar terms protraction and retraction are used most commonly for anterior and posterior movements of the shoulder. 50 Terms of Movement Elevation raises or moves a part superiorly, as in elevating the shoulders when shrugging, the upper lid when opening the eye, or the tongue when pushing it up against the palate. Depression lowers or moves a part inferiorly, as in depressing the shoulders when standing at ease, the upper lid when closing the eye, or pulling the tongue away from the palate. 51 Structure of Terms Anatomy is a descriptive science and necessarily requires names for the many structures and processes of the body. The terminology fully adheres to Terminologia Anatomica (1998), approved by the International Federation of Associations of Anatomists (IFAA) Anatomical terms provide information about a structure's shape, size, location, or function or about the resemblance of one structure to 52 another. Structure of Terms EXAMPLES: the deltoid muscle, like the symbol for delta, the fourth letter of the Greek alphabet. The suffix -oid means like therefore, deltoid means like delta. Biceps means two-headed and triceps means threeheaded. Some muscles are named according to their shape the piriformis muscle, for example, is pear shaped (L. pirum, pear + L. forma, shape or form). Other muscles are named according to their location. The temporal muscle is in the temporal region (temple) of the cranium (skull). In some cases, actions are used to describe muscles for example, the levator scapulae elevates the scapula (L. shoulder blade). Eponyms An eponym is a person (real or fictitious) from whom something is said to take its name Very common in medicine and Anatomy, pay attention as you will see them on board exams Examples: Sternal angle – angle of Louis Major pancreatic duct -duct of Wirsung Thank You 55