(EXAM1)Chapter 1
1. Which of the three general divisions of the field of genetics applies to a study of
pedigrees to follow the inheritance of a particular trait?
A. population genetics
B. molecular genetics
C. transmission genetics
2. Which correctly shows the flow of genetic information during gene expression?
A. RNADNAProtein
B. ProteinDNARNA
C. DNARNAProtein
Chapter 10
3. Consider a double stranded DNA molecule that contains 32 base pairs. How many
purine bases are present in such a molecule
A. 16
B. 32
C. 64
4. How did Chargaff’s rules contribute to elucidation of the structure of DNA?
A. They revealed the base pairing combinations of A matched to T and G
matched to C
B. They revealed that DNA was the genetic material
C. They revealed that DNA con only exist as a double stranded molecule
Chapter 11
5. What is the primary function of a telomere?
A. Epigenetic modification
B. Initiation of supercoiling within the chromosome
C. Protection of the end of linear chromosomes from degradation
6. Which of the following is an example of an epigenetic change in a eukaryotic
genome?
A. Addition of methyl groups to cysteine in the promoter region of a gene
B. Substitution of an AT base pair by a GC base pair in a gene as a result of a
mistake during DNA replication
C. A deletion that simultaneously removes two genes from the genome
Chapter 12
7. Where are RNA primers synthesized during lagging strand synthesis?
A. At the 5’ end of every Okazaki fragment
B. At the 3’ end of every Okazaki fragment
C. At multiple locations within each Okazaki fragment
8. Why is primase required for DNA replication?
A. DNA polymerase cannot initiate a new strand of polynucleotide, but
primase can start a new strand without a pre-existing primer.
B. Primase is able to correct errors in base pairing but DNA polymerase lacks
this activity
C. Sometimes there are insufficient levels of deoxyribonucleotides, and in
those instances primase can substitute ribonucleotides.
Chapter 14
9. What is the function of the spliceosome?
A. Spliceosomes generate polypeptides from amino acids using mRNA
sequences to specify the order of specific amino acids
B. Spliceosomes catalyze cleavage of pre-mRNA at the 3’ end of one exon and
join that free end to the 5’ end of the next exon
C. Spliceosomes catalyze production of DNA sequences using RNA sequences
as templates
10. Consider a base pair change that occurs during DNA replication within an intron
sequence in a gene. What will be the most likely effect of such a mutation on the
protein that is encoded by that gene?
A. The protein will have an abnormal amino acid sequence
B. The protein will be shorter than normal because transcription will not
terminate prematurely
C. No effect, because base pair sequences within introns do not specify amino
acid sequences in proteins.
(EXAM2) Chapter 2
11. True or False: Homologous chromosomes contain all of the same genes but not
necessarily the same alleles
12. A cell has 16 chromosomes. How many chromosomes would its daughter cells
have after meiosis?
A. 4
B. 8
C. 16
Chapter 3
13. A testcross produces progeny that are ½ tall and ½ dwarf. What is the genotype
of the unknown parent if the dominate phenotype is tall?
A. DD
B. Dd
C. dd
14. On the basis of segregation and independent assortment, how many different
types of gametes can be formed from an organism that has a diploid number of 12?
A. 2
B. 12
C. 64
Chapter 4
15. What is the pseudo-autosomal region of a human’s genome?
A. The regions of homology between the X and Y chromosomes that undergo
recombination during meiosis
B. The hemizygous regions that are present in only one copy of a gene
C. A pseudoautosome is a false or fake autosome. Therefore, the
pseudoatutsomal region could not, by definition, be part of an autosome pair
16. What is the relationship between Barr bodies and dosage compensation?
A. Barr bodies are visible only in females
B. Barr bodies are inactivated X chromosomes in females
C. Barr bodies stain positive for DNA
Chapter 15
17. Which amino acid is coded for by a start codon?
A. Histidine
B. Methionine
C. None
18. Which amino acid is coded for by a stop codon?
A. Histidine
B. Methionine
C. None
(EXAM3) Chapter 5
19. If an individual with blood type O mates with an individual with blood type AB,
which of the following blood types are NOT possible for their progeny?
A. A
B. B
C. AB
20. A female is a carrier for an X-linked recessive trait, assuming the father is not
affected, what proportion of their daughters will be carriers?
A. 0%
B. 25%
C. 50%
Chapter 6 (pedigrees-genetic testing)
21.
If III-2 and III-7 mated, then what is the probability that their first child
would be affected?
A. 1/4
B. 1/2
C. 3/4
22. A trait in a human pedigree has the following features:
The trait affects males predominately
The trait is passed from an affected male through his unaffected daughter to
his grandson
The trait is not passed from father to son
Affected females always have an affected father
A. X-linked recessive
B. Autosomal recessive
C. X-linked dominant
Chapter 7
23. In a three-point testcross the nonrecombinate progeny are A+B+C+ and abc. The
double-crossover progeny are A+B+c and abC+. Which locus is located in the
middle?
A. gene A
B. gene B
C. gene C
24. What is the explanation for recombinant-type gametes with linked genes?
A. Double stranded DNA is broken and then rejoined such that sections are
switched between the maternal and paternal copies of the chromosome
B. Recombinant-type gametes with linked genes can result form independent
assortment
C. Double crossovers between two linked genes results in recombinant-type
gametes