Chapter 1: Introduction to Anatomy/Physiology Chapter 2: The Chemical Level of Organization • What is anatomy? • The study of internal and external structures of the body and the physical relationships among body parts. • What is physiology? • The study of how organisms perform their vital functions through the use of internal and external structures of the body. • Chemical/Molecular Cellular (simplest form of life) Tissue Organ Organ System Organism • Figure 1-1 • Homeo : unchanging + stasis : standing • The ability to continue a stable internal environment • Maintaining homeostasis is essential for all living organisms to survive. • Homeostatic Regulation: the adjustment of physiological systems to continue homeostasis • 2 Mechanisms Involved • 1-Autoregulation • 2-Extrinsic Regulation • Autoregulation: or intrinsic regulation • Automatic adjustment in response to an environmental change • Extrinsic Regulation: • Nervous system or endocrine system regulation • When a homeostatic regulation occurs there are 3 parts: • 1- Receptor: a sensor that is sensitive to an environmental change • 2- Control Center: area which receives and processes the information from the receptor • 3- Effector: a cell or organ that responds to the commands • Negative Feedback: • Controlling or going against the change • Example: Body gets too warm Negative Feedback: Body begins to sweat • Primary mechanism of homeostatic regulation • Positive Feedback: • Initial stimulus produces a response that exaggerates the effects • Example: Break in blood vessel Damaged cells release chemical clotting begins additional chemicals released clotting accelerates • Important in accelerating processes that must proceed to completion quickly • The Integumentary • The Skeletal • The Muscular • The Nervous • The Endocrine • The Circulatory • The Lymphatic • The Respiratory • The Digestive • The Urinary • The Reproductive • Anatomical Position • Hands at sides with palms facing forward • Supine: body laying with face up • Prone: body laying with face down • 4 Abdominopelvic Quadrants • Right Upper Quadrant (RUQ) • Right lobe of liver, gall bladder, right kidney, portions of stomach, small and large intestines • Left Upper Quadrant (LUQ) • Left love of liver, stomach, pancreas, left kidney, spleen, portions of large intestine • Right Lower Quadrant (RLQ) • Cecum, appendix, portions of small intestine, reproductive organs, right ureter • Left Lower Quadrant (LLQ) • Most of small intestine, portions of large intestine, left ureter, reproductive organs 9 Abdominopelvic Region • Right Hypochondriac Region • Epigastric Region • Left Hypochondriac Region • Right Lumbar Region • Umbilical Region • Left Lumbar Region • Right Inguinal Region • Hypogastric Region • Left Inguinal Region • • • • • • • • • • • • • • Superior: above, at a higher level Inferior: below, at a lower level Anterior: front Posterior: back Ventral: Belly side Dorsal: Back side Cranial: the head Caudal: the tail/coccyx Medial: towards the midsagittal plane Lateral: away from midsagittal plane Proximal: close to attached base Distal: away from attached base Superficial: towards surface Deep: farther from surface, deep • Figure 1-8 • Transverse Plane: Divides the body into superior and inferior sections • Frontal Plane or coronal plane: Divides the body into anterior and posterior sections • Sagittal Plane: Divides the body into right and left halves • Dorsal Body Cavities • Cranial Cavity • Spinal Cavity • Ventral Body Cavities • The diaphragm separates: • Thoracic Cavity • Right Pleural Cavity • Mediastinum • Pericardial Cavity • Parietal Pericardium---opposing surface • Visceral Pericardium---layer covering the heart • Left Pleural Cavity • Abdominopelvic Cavity • Abdominal Cavity • Pelvic Cavity • What percentage of each element is found in the Human body? • Oxygen---A component of water, important for respiration • 65% • Carbon---Found in all organic molecules • 18.6% • Hydrogen---A component of water • 9.7% • Nitrogen---Found in proteins, nucleic acids • 3.2% • Calcium---Found in bones and teeth • 1.8% • Usually do not contain carbon and hydrogen atoms as part of the primary structure • Most important • Carbon Dioxide • Byproduct of cell metabolism • Oxygen • Gas required for important metabolic reactions • Water • Accounts for most of our body weight • Acids, bases, salts • Contains carbon, hydrogen and oxygen • Most familiar are sugars and starches • Most important sources of energy that are metabolizes vs stored • 3 main types • Monosaccharides • Simple sugar • Common example would be Glucose and is the most important metabolic fuel for the body—Chemical formula?? • Can dissolve quickly in water and is rapidly distributed throughout the body • Disaccharides • Is 2 mono’s joined together • Complex molecule • The body must disassemble them before they can be useful • Polysaccharides • Multiple Disaccharides joined together • Our digestive tract can break these molecules into Mono’s • Starch is a common example • Cellulose-more energy expended through chewing than made back through digestion • Contains carbon, hydrogen and oxygen • Familiar lipids include fats, oils, and waxes • Most are insoluble in water • Form an essential component in all cells • Phospholipids • Account for 12-18% of total body weight in males and 18-24% in females • Common Examples • Fatty Acids • Glycerides • Steroids • Phospholipids • Most abundant in human body • Account for 20% of total human weight • Functions: • Support • Movement • Transport • Buffering • Metabolic Regulation • Coordination and control • Defense • Structure: • Contain long chains of amino acids