University of Michigan
CleanTech Innovation
Michigan-China Clean Tech
10 December 2010
Jim Deane
Senior Licensing Specialist
Office of Technology Transfer
UM Tech Transfer Mission
Our Mission
To generate benefits for the University, our
community, and society
through the transfer of University innovations
Bayh-Dole Act of 1980
$1.15B/year Research Base (#1 Public FY10)
>85% Federal Funding (NIH, NSF, DoD, etc)
UM Invention Portfolio 2010
~ 4800 Inventions since ca. 1990
~300 – 350 new disclosures/year
“From Cancer to Concrete”
40% CoE, 40% Med, 20% Other
~100 License Agreements/year
8 – 12 Startup Companies/year
~$15M Royalties (excl. 1-time income)
Top-5 Tech Transfer ranking in USA (peers
MIT, Stanford, U. Wisconsin, U. Washington)
UM CleanTech Portfolio 2010
213 Inventions (~5%):
55 Licensed
13 Optioned
6 Under Negotiations
70 Active Marketing
10 On Hold – Technology Development
22 On Hold – Business Development
38 Closed/Non-Lead
U. Michigan CleanTech Invention Disclosures
45
40
35
30
25
20
15
10
5
0
1991
1993
1995
1997
1999
2001
2003
2005
2007
2009
UM CleanTech Portfolio 2010
Principle Technical Areas
Photovoltaics/Conversion (Solar)
Energy Storage
Catalytic Materials / Biofuels
Low Power Use Devices/Strategies
Energy Generation/Harvesting
Remediation/Clean Manufacturing
Notable UM CleanTech Projects
Licensed to Existing Companies:
• S2 Yachts – (Great Lakes Environmental
Monitoring Buoys) Meadows (MHL/NAME)
• Metamorphix Global (Specialty Concretes) Li
(CivEng)
Created under Sponsored Research:
• Global Photonic Energy Corp (OLED
Photovoltaics) Forrest (OVPR/EECS)
• BASF (Catalysts) Yaghi (LSA Chem)
Notable UM CleanTech Projects
Launched Startup Companies:
• Sakti3 (Auto Batteries) Sastry (MSE) 2008
• Vortex Hydro Energy (VIVACE) Bernitsas 2010
• Ambiq Micro (Low Power Microprocessors)
Sylvester (EECS) 2010
Companies In Development:
• A.B.C. (Battery Power Mgmt) Shin (EECS)
• ArborLight (LED Lighting) Shtein (EECS)
• CSquared (Battery Manuf.) Mohanty (Dearborn)
Backup Slides
Tech Transfer Organization
– Licensing Function
• Disclosure, Protections, Marketing, Agreements,
COI
– New Business Development
• “Business Formation Consultants”, Link to resources
– IP Management and Legal Assistance
• OGC resources for patent process, legal mentoring,
business support, litigation management
– Business Support
• Marketing, M-I-R, Data support, Revenue
Management, Patent Administration, Office
Management, Talent and Student Entrepreneurship
OTT Services
• Assist researchers with all intellectual
property and commercialization issues
associated with their discoveries:
– Invention reports
– IP Clauses in Sponsored Research
– Patent filing and prosecution management
– Copyright and trademark issues
– Negotiate license and option agreements
OTT Services
• Marketing inventions
• Non-disclosure agreements
• Outgoing material transfer agreements
• Start-up business formation
• Early-stage commercialization funding
• Ownership and conflict-of interest issues
“One stop shop for all faculty
Intellectual Property issues”
Business Formation
Who are we?
• Specialized internal group to assist with startups
• 3 FTE’s plus 4 MIR’s – Every one with startup
experience
Startups – what we do
• Meet with faculty to discuss inventions and startups
• Help to formulate the business plan
• Recruit talent for startups
• Recruit mentors and industry experts to advise startup
groups
• Help to formulate and execute the funding plan
• Co-ordinates with CFE, AA SPARK, SBTDC, MEDC,,
ZLI, Erb, other universities, consultants, venture capital,
angel groups, private investors and industry to get the
startups the resources they need
U-M Tech Transfer and FY09
A good year, despite the economic challenges
350 inventions reported
- a new record!
➤ 78 license agreements
➤
$18.3 million in revenues
- 20% increase in royalties + $3 million in equity
➤ 8 new business startups
- 83 new startup ventures since 2001
➤
U-M Tech Transfer Results
College of Engineering Activity
College of Engineering Inventions
AOSS;
1%
Biomedical;
9%
Chemical;
8%
Civil & Environmental;
2%
Aerospace; 3%
Other;
1%
Nuclear Eng & Rad
Sciences; 3%
Naval Arch &
Marine Eng; 2%
EECS; 42%
Materials Science
& Eng; 6%
Mechanical; 22%
IOE; 1%
U-M Tech Transfer Revenues
U-M Tech Transfer Startups
U-M Licensed Startups
FY 2003
FY 2004
FY 2005
FY 2006
FY 2007
FY 2008
FY 2009
GMP
Cancer Diag
Cellectar
Accuri*
CastAnalysis*
FlexSys*
Nephrion*
Biotectix**
GMP
Invia*
Immunotherapy
McCreadie
OncoImmune
Group*
Cyclos
Semiconductor
ImBio*
Buck 80
ACSI*
NanoMag*
Avicennna*
OtoMedicine*
Seventh Sense
Biosystems
Alerion
Biomed
Ascenta
Xoran*
Pipex*
Incept*
InflaRx GmbH
OcuSciences*
Advangen
Neural
Intervention
Mayaterials*
SensiGen*
Locomatix*
Lycera*
Soar *
Mobius**
nPoint*
Compendia
Biosciences*
Sandbox Tech
Polytorx *
Avidimer*
PreSense*
Cielo
MedSolutions*
Biodiscovery*
MedHub *
Dentigenix
Southern
Industries*
MC3
Biomaterials*
NeuroNexus*
ProView
Atheron
Etubics
Opteos*
Ablation
Frontiers
Med
CoE
Zattoo**
Polaris Surgical
Instruments
Tissue
Regeneration
System*
Omni Science*
MedSpoke*
Arbor Photonics*
InCytu
ePack*
Sakti3*
Armune
Bioscience*
Other
*/** indicates Michigan HQ (*) or office (**)
Italics = ceased operations or returned technology
Integrated Sensor
Technologies
Phrixus
Pharmaceuticals*
Umerse
Securus Medical
2008 Tech Transfer Benchmarking
Invention Reports
New Patent
Apps
Issued
Patents
New
Agreements
Annual
Revenue $MM
Startups
Licensing
Staff
Total
Staff
MIT
522
JHU+APL
500(?)
MIT
122
U Wash
205
MIT
20
MIT
89.1
U Wisc
19
U Wisc
69
Stanford
400
U IL
367
U Wisc
85
Stanford
107
UCB
14
U MN
83.3
MIT
18
Stanford
43
U IL
363
MIT
282
U-M 2008
75
MIT
98
U-M 2008
13
Stanford
62.5
U Wash
16
U MN
42
U-M 2009
350
U Wisc
270
U-M 2009
72
JHU+APL
92
Duke
12
UCSF
62.4
U MN
14
U Wash
41
U Wisc
350
U Wash
226
U Wash
56
U-M 2008
91
JHU+APL
12
U Wash
47.0
JHU + APL
13
U IL
36
U Wash
349
Cornell
222
Cornell
54
U-M 2009
78
Stanford
12
UCLA
32.8
Cornell
12
UCLA
32
UCSD
330
UCLA
221
U IL
54
U Wisc
68
U CO
11
Penn
12
MIT
31
UCLA
314
U CO
188
UCSD
45
Cornell
65
U IL
11
22.7
UCD
12
Cornell
30
U-M 2008
306
UCSD
180
UCLA
42
U MN
64
U Wash
9
U-M 2009 18.3
UCSF
11
Penn
29
JHU+APL
305
U-M 2009
151
JHU+APL
40
U IL
61
U-M 2009
8
JHU+APL 11.2
OSU
10
UCSD
29
Pitt
244
U-M 2008
132
U MN
37
Pitt
58
Cornell
5
U IL
10.3
Stanford
10
U-M 2009
27
Cornell
242
UCB
102
Pitt
36
U CO
58
Pitt
3
UCD
8.0
UCLA
10
U-M 2008
27
U CO
237
Pitt
100
UCB
36
UCSF
49
U MN
1
Cornell
6.8
U IL
9
JHU+APL
24
U-M 2008 25.0
UCSD
U MN
217
UCD
93
UCSF
35
UCSD
43
OSU
n/a
Pitt
6.7
UCSD
9
Duke
21
UCSF
200
UCSF
76
U CO
28
UCLA
38
Penn
n/a
U CO
6.1
U-M 2008
8
UCD
20
UCD
181
U MN
58
UCD
21
UCD
24
Penn State
n/a
UCB
5.2
U-M 2009
8
UCSF
18
UCB
155
Duke
n/a
Duke
n/a
UCB
23
U Wisc
n/a
Duke
n/a
Duke
7
Pitt
18
Duke
n/a
OSU
n/a
OSU
n/a
Duke
n/a
UCD
n/a
OSU
n/a
Pitt
7
OSU
17
OSU
n/a
Penn
n/a
Penn
n/a
OSU
n/a
UCLA
n/a
Penn
n/a
UCB
7
U CO
16
Penn
n/a
Penn State
n/a
Penn State
n/a
Penn
n/a
UCSD
n/a
Penn State n/a
U CO
5
Penn State
11
Penn
State
n/a
Stanford
n/a
Stanford
n/a
Penn State
n/a
UCSF
n/a
Penn State
4
UCB
10
U Wisc
n/a
FY09 CoE Highlights – Success Stories
➤
Histosonics, a U-M startup, has obtained an option to obtain an exclusive license to histotrypsy
technology being developed by Drs. Cain, Roberts, Xu, Fowlkes and Hall. A prototype has been
built and animal testing for the first application, BPH (benign prostate hyperplasia) have been
completed. Clinical trials are being planned for 2010.
Biotectix, a U-M start up based on developing conductive coatings from David Martin's lab in
Material Science and Engineering. The company plans to commercialize bioactive coatings to
improve the performance of implantable devices.
S2 Yachts, a boat manufacturer in Holland, MI, has licensed designs for marine buoys and
sensors packages optimized for Great Lakes health monitoring programs. The designs stem from
years of collaboration with Guy Meadows and the Marine Hydrodynamics Laboratory in the
College of Engineering. S2 Yachts is diversifying their product lines beyond the production of
luxury boats, an industry hit hard by the current economic crisis. Modified versions of the sensorequipped buoys will also target ocean-sensing applications.
Life Magnetics has developed and validated a prototype, rapid culturing diagnostic device with
potential applications determining anti-biotic susceptibility of MRSA and personalized, targeted
chemo-therapy treatments. Brandon McNaughton, a research scientist in BME has used OTT
Gap funds, MUCI, CTSA and Coulter Foundation support to build the initial device and research
potential markets. He plans on launching a startup in the next nine months.
Seventh Sense Biosystems, Inc. is a UM startup based on multiphasic particles developed in
Joerg Lahann's lab in Chemical Engineering. The company aims to use the switchable materials
platform to develop a diagnostic system for patients, that would be analogous to the check
engine light in automobiles, to enable evaluation of health information.