Leader: Course: Instructor: Date: Human Physiology Unit 5B: Metabolism Supplemental Instruction Iowa State University Paige Stieneke BIOL 256 Dr. Karri Haen April 26, 2013 Metabolism 1. Define metabolism: 2. (Catabolism, anabolism) is the synthesis of larger molecules from smaller ones, while (catabolism, anabolism) is the breakdown or hydrolysis of complex molecules into simpler ones. 3. __________ is also known as the “Fed” state and is the time during and shortly after nutrient intake 4. _________________ or “Fasting” is the time when the GI tract is mostly empty 5. What is the metabolic process where food is broken down to yield energy? 6. True or False: All tissues use glucose to synthesize ATP Absorptive State 1. During the absorptive state, (catabolism, anabolism) occurs to (build, break) molecules. 2. Amino acids are converted into ____________ 3. Glycerol and fatty acids are converted into ________________ 4. Glucose is stored as ______________ 5. Excess amino acids are _______________ and are either used for energy or stored in the _______ Tissue or Organ Muscle Liver Fat Amino Acids Glucose 6. What hormone controls the absorptive state? 7. Identify what stimulates this hormone’s secretion: a. Increased blood _________ b. Elevated blood ____________levels c. Gastrin, CCK and secretin 8. What does this hormone enhance? 9. What is the disease where glucose becomes unavailable for most body cells? 10. Identify the two causes of diabetes: a. Inadequate ___________ production b. ____________ insulin receptors Postabsorptive State 1. During the postabsorptive state, (catabolism, anabolism) occurs to (build, break) molecules. 2. Proteins are broken down into _________________ 3. Triglycerides are converted into ______________ and ___________ 4. Glycogen is converted into ___________ Supplemental Instruction 1060 Hixson-Lied Student Success Center 294-6624 www.si.iastate.edu 5. In the muscle, protein is broken down into _______________, and ____________ is converted into ATP and pyruvic acid. 6. In the liver, amino acids, pyruvic acid, glycogen and fat are all converted into __________. Fat is also converted into ________________ to make ATP 7. What hormone controls the postabsorptive state? 8. What does that hormone enhance? a. b. __________________ in adipose tissue c. __________ sparing Calorie Yields For each gram of food consumed, you get: a. Proteins: b. Lipids: c. Carbohydrates: Regulation of Food Intake Hormone Location Neuropeptide Y Cholecystekinin Ghrelin Leptin Function Metabolic Rate 1. Metabolic rate is the rate of ________________ equal to the total heat produced by all chemical reactions and mechanical work in the body. 2. __________________________ is the energy that the body needs to perform its functions at rest 3. __________________________ is the total rate of kilocalorie consumption fueling all ongoing activities Supplemental Instruction 1060 Hixson-Lied Student Success Center 294-6624 www.si.iastate.edu