HUMAN PHYSIOLOGY – HS2410 SPRING 2016
The Faculty, Fellows, Students, and Staff of the Physiology Department welcome you to the Human Physiology
HLSC2410 course. Physiologists explore the normal functioning of living organisms. In Human Physiology,
functional processes within each organ system of our bodies are studied to determine how homeostasis, the
maintenance of an optimal internal environment that supports cellular life, is achieved. These processes, resulting
from regulated functions of each organ system, involve coordinated neural and hormonal communication systems.
We will study each system individually, and as the course progresses, you will learn to integrate each system to
understand how homeostatic regulation of the whole body attempts to return abnormal function to normal
homeostasis. Our goal is to help you achieve a working knowledge of physiology, not just a memory bank full of
physiological facts, as you acquire an understanding of and an appreciation of organ function and homeostatic
control mechanisms. E. H. Starling, a famous physiologist of the early 20th century, once remarked that "The
physiology of today is the medicine of tomorrow." We hope your efforts to learn physiology will equal or surpass
our efforts to teach you this most important science for all healthcare professionals.
I. COURSE CO-DIRECTORS: Dr. Raymond E. Shepherd and Dr. Lisa M. Harrison-Bernard
The Course Co-Directors are directly responsible for supervision and administration of HS2410. Any policy or
schedule change will be formally announced by Dr. Shepherd and/or Dr. Harrison-Bernard by E-mail or Moodle. Dr.
Harrison-Bernard is pleased to schedule an appointment by E-mail to meet with you in her office. She is unable to
meet with students that do not have a prior appointment. Dr. Shepherd has an open door policy – if the door is open,
come in. However, prior appointments will reserve your requested date and time with Dr. Shepherd.
II. INSTRUCTORS
Raymond E. Shepherd, PhD
Lisa M. Harrison-Bernard, PhD
Anthony A. Duplanty, PhD
Jason D. Gardner, PhD
Alan J. Mouton, BS; PhD Student
Andrew A. Pellett, PhD
Andrew L. Pitt, CRNA, DNP
Annie M. Whitaker, PhD
Barry J. Potter, PhD
Flavia M. Souza-Smith, PhD
John B. Zamjahn, PhD
Margaret A. Zimmerman, PhD
Stefany D. Primeaux, PhD
Building/Rm
Office Phone
MEB, 7C29
568-6191
MEB, 7C7
568-6175
MEB, 7A2
568-6171
MEB, 7B1
568-7252
MEB, 7F3
568-6171
N/AH, 6A-1
568-4229
N/AH, 154
896-9478
MEB, 7A2
568-6171
MEB, 7C10
568-3385
MEB, 7A2
568-2203
N/AH, 6A-5
568-4234
Tulane Med Sch
MEB, 7159D
568-2633
Page 1 of 7
E-mail address
rsheph@lsuhsc.edu
lharris@lsuhsc.edu
adupl4@lsuhsc.edu
jgardn@lsuhsc.edu
amout2@lsuhsc.edu
apelle@lsuhsc.edu
apitt@lsuhsc.edu
awhita@lsuhsc.edu
bpotte@lsuhsc.edu
sfouz1@lsuhsc.edu
jzamja@lsuhsc.edu
mzimmer5@tulane.edu
sprime@lsuhsc.edu
III. LEARNING PHYSIOLOGY
Doing well in Physiology will require concentrated effort on your part, as you will become involved in your
own learning process. The following tips will enhance your chances for success in this course:
1. A cursory understanding of the material is only the foundation from which to begin studying. Use the questions
in the textbook to help guide your understanding of the physiologic concepts presented in class.
2. Facts are only memorized; understanding physiology requires integration and application of concepts. Ask
yourself, “What is the primary concept this unit covers?” Then study to understand the application of that
concept to physiologic regulation of whole-body homeostasis.
3. One learns by hearing what is being taught, observing what is being taught, experiencing what is being taught,
and then teaching another person what was taught to you. Use this process during your learning.
4. Read carefully the assigned and relevant chapters and sections in the textbook before class sessions.
5. Take your own notes during lectures. As soon after the lecture as possible, integrate your notes with the textbook
(focus on tables and figures) and other lecture materials. Look at the material from different angles. Embrace this
new experience of learning.
6. Form small study groups and meet at least once per week throughout the entire semester. Review class material
by taking turns “teaching” the other members of the study group. You will really understand physiology when
you can help another student learn physiology.
7. Apply facts and concepts presented in the lecture to the clinical scenarios presented in the textbook. Moderate to
severe exercise is used as a clinical scenario throughout the course because we can easily visualize this activity.
IV. LECTURES, ATTENDANCE, TEXTBOOK
Lectures: Class meets Tues and Fri from 8-10 AM (LH-C) in the Nursing-Allied Health Bldg. Class begins at 8 AM
sharp. The lectures support and supplement the textbook. The textbook will help you understand basic physiological
concepts as applied to patient care. Read the assigned chapter in the textbook prior to class. You must achieve a
working knowledge of physiology, not just memorizing physiological facts. Our emphasis will be on the application
of physiological concepts for patient care.
Textbook: Human Physiology: The Mechanisms of Body Function by Widmaier, Raff, and Strang, 13th edition
(McGraw-Hill: ISBN 9780073378305). Earlier versions of the textbook are not recommended. Our PPT slides are
not equal to the textbook. You are responsible for applying the textbook material to supplement the PPT slides that
we present in class. Read and study the textbook as you study the slides.
Laboratory: The ECG lab (MEB-MDL #6) will be given on Tues and Thurs from 1-4 PM. You need attend only
one session of this lab (AbPsych students must have lab on Tues). The MDL labs are on the 4th floor of the Medical
Education Building (MEB). Clinical correlation labs will be in LH-C from 1-3 PM on Tuesdays for all students.
ADOBE presentations are optional and will be posted to the Moodle website for you to listen wherever and
whenever you prefer. The ADOBE presentations are included to enhance your understanding of the material being
presented in class.
Cell Phones: Cell phones are to be on vibrate during class and kept out of sight. If an emergency exists, take the call
outside of the classroom. Please, respect our learning environment.
Electronics: Tablets, iPad, notebooks, and small computers may be used in the classroom for the sole purpose of
viewing the lecture material and taking notes. Your face is better to communicate with than a computer lid. You may
record, but not videotape the lecture. Do not take snapshots with any electronic devices.
Tutoring: Tutoring for the course is provided by our advanced physiology PhD students. Alan Mouton is the
assigned tutor for the course and will conduct weekly question and answer review sessions. You may contact John
Maxi and Jacques Mayeux for private tutoring.
Page 2 of 7
Students with Disabilities: Students who have authenticated disabilities must petition the Nursing School
Administrative Assistant Dean, Ms. Kendra Barrier. Ms. Barrier will inform the course director that you will receive
additional time and/or special accommodations for exams or other course functions.
Academic Honesty: Use of any unauthorized material or method other than your knowledge and memory to answer
questions on an exam constitutes cheating and will result in your failing that exam and possibly failure of the course.
The Dean of the School of Nursing will be notified.
Clicker sign-up: Purchase you Turning Technologies Clicker Device from the bookstore. Included in the box with
the clicker device is a card with a number on it that you will need to register for the class at Turning Technologies.
V. EXAMINATIONS AND GRADING
Exam Schedule: Four unit exams will be given during the course; Exam 5 is a Comprehensive Final. Unit exams are
Tuesdays 8 AM-10 AM. BSN students will report to the Computer Testing Lab, 5th Floor, N/AH. CARE students
will report at the same time to LH-A N/AH building, with laptop computer, Respondus lockdown browser software,
power cord, and an internet cable. You will have 2 hours to complete the exam once the exam starts. Students with
documented disabilities will test in the ADA room. ADA students will be given 3 hr to complete the exam once
started. There will be no extension of time.
Attire and Personal Material: Caps and other headgear, and water and food are not allowed during the exam. We
will supply paper upon which you can write or calculate as you answer the exam questions. You provide a pen or
pencil. Sign your papers before leaving the NSTC or LH-A test site so when you come to review the concepts of the
exam with us, we will be able to find your paper. Moodle provides calculators, if needed. Leave cell phones turned
off in your book bag. If you expect an emergency call during the exam, silence your cell phone, leave it with the
proctor so we can notify you should you receive a call. All material must be stored in the designated storage areas in
the NSTC. CARE students will place all personal materials in the front of LH-A before being seated in every third
seat of alternate rows for the exam period.
Exam Format: All examinations will consist of 50 multiple-choice questions that are submitted to the co-directors
for final review. Each exam question will have 4 possible choices that utilize clinical scenarios that will test your
understanding (know and apply facts) of physiologic principles that have been covered in lecture, lab, and in the
textbook. Exams will start promptly at 8 AM. Be seated quickly, activate Respondus, and log into Moodle. The
password to activate the exam will be posted at the door (NSTC) or on the front screen (LH-A). Exams are limited to
exactly 2 hours. If you arrive 1 hour after the exam starts, you will have missed the exam, and will have to make
arrangements to take a make-up exam with documentation from Ms. Barrier.
Missing an Exam: Students must submit hand-written documentation from Ms. Barrier to the course director for
missing an examination period. Please inform the Course Director before the exam if you will be absent. If a student
misses an exam because of an emergency, informs the course director within 24 hours after the exam has been given,
and has the necessary documentation for their absence, the student will be offered a make-up exam. Make-up exams
may be multiple choice, but likely will be oral and essay format. Students with a valid excuse must take a “make-up”
exam within one week of returning to school. It is the student’s responsibility to schedule this make-up exam. Failure
to take the exam or the make-up exam results in a “0” for that exam. This grade cannot be replaced with the final
exam grade. This does not apply to clicker quizzes. There are no make-up clicker quizzes given for any student for
any reason. Students who submit documentation from Ms. Barrier to a Course Director for missing a clicker quiz
will receive the attendance credit only for the missed quiz.
Exam Reviews: Exams are evaluative and not instructional. We will not review the exam key with you. We will
discuss physiological concepts related to the notes you wrote on your scratch paper during the exam.
Page 3 of 7
Clicker Quizzes: Make certain your clicker is in working order and carry extra batteries. Connection with the class
computer is indicated when the projected clicker number darkens on the overhead screen. Clickers may take up to 5
sec to connect. Submit your clicker answer at least 5 sec prior to the end of the question timer. Check with
einstruction.com after every clicker quiz to make sure your clickers made contact with their site. Check with us if
Turning Point did not record your score. Notify us that day if contact was not made. No notification =No Credit. If
your clicker is not working, you may take the quiz by paper and pen only if you are seated in the front of the
classroom during the entire quiz. One point will be earned for attendance and one point will be earned for answering
each clicker question correctly. All clicker points are added together and constitute Exam #6 for the semester. The
percentage clicker quiz score is determined by dividing [[number correct]/[total]] X 100. If we have 100 clicker
quizzes during the semester, and you score 180 of the 200 total points, you have 180/200 or a score of 90% for Exam
#6.
VI. STUDENT EVALUATION
Exams are graded as % Score: [Correct/Total X 100]. Each exam question is analyzed by a statistical program, and
both Drs. Harrison-Bernard and Shepherd scrutinize each answer before we release the grades on Moodle. We
recognize you may have a ‘bad hair day’ and do poorly on one unit exam. If your Final Comprehensive Exam #5
score is higher than any one score on unit Exams 1-4, then the final exam score will substitute for that lowest score,
as well as, be counted for the Exam #5 score. The Exam #6 for clicker quizzes will NOT be included for this grade
substitution. Final grades are based on your TOTAL score (600 pts) from the five exams (500 pts) plus the clicker
quizzes (100 pts). The grading scale is 90%-80%-70%-60% for A-B-C-D, respectively. Scores are absolute. A final
score of 539 is a “B” and a score of 540 is an “A.” We do not “curve” the exams or the grades. The Course Final
Grades are determined by summing the % correct for each exam. The total summed score is the Total Points earned
during the semester.
Exam
Pts
Final
Percentage
Total Points
Exam I
Exam II
Exam III
Exam IV
Exam V-Final
Exam VI (Clickers)
100
100
100
100
100
100
A
B
C
D
F
90 – 100
80 – 89
70 – 79
60 – 69
< 59
540 - 600
480 - 539
420 - 479
360 - 419
000 - 359
Total Points
600
Spring 2016
Classes begin Wed 13Jan16
Mardi Gras Tues 9Feb16
Spring break Tues 22Mar16 – Tues 29Mar16
Reading day Fri 6May16
Final Exams Mon 9May16 – Thur 12May16
Last day of semester 13May16
Pre-commencement Wed 18May16
Graduation Thur 19May16
Page 4 of 7
VIII. COURSE SCHEDULE
No.
Day/Date TIME and TOPIC
Instructor______
01
02
F 15 Jan
F 15 Aug
8
9
Homeostasis: Maintenance of Internal Environment (Ch 1)
Cell Physiology: Cell Function – Metabolism (Ch 3)
Dr. Shepherd
Dr. Shepherd
03
04
LAB
05
06
T 19 Jan
T 19 Jan
T 19 Jan
F 22 Jan
F 22 Jan
8
9
1
8
9
Cell Physiology: Membranes – Molecular Structure (Ch 3)
Cell Physiology: Diffusion, Osmosis (Ch 4)
How To Study
Cell Physiology: Membrane Transport (Ch 4)
BioCommunication: Electrical Properties of Membranes (Ch 4)
Dr. Primeaux
Dr. Primeaux
Dr. Harrison-Bernard
Dr. Primeaux
Dr. Primeaux
07
T 26 Jan
08
T 26 Jan
LAB #1 T 26 Jan
09
F 29 Jan
10
F 29 Jan
8
BioCommunication: Action and Graded Potentials (Ch 6)
9
BioCommunication: Synapses and Signaling (Ch 6)
1 PM Fluids, Electrolytes, and Resuscitation
8
BioCommunication: Neurotransmitters & Receptors (Ch 5)
9
BioCommunication: Sensory Physiology (Ch 7)
Dr. Primeaux
Dr. Primeaux
Dr. Shepherd
Dr. Primeaux
Dr. Primeaux
11
12
8
9
Dr. Duplanty
Dr. Duplanty
T 02 Feb
T 02 Feb
BioCommunication: Body Movement and Reflexes (Ch 10)
BioCommunication: Skeletal Muscle (Ch 9-A)
Exam #1: 8-10 AM, Fri, 05 Feb 2016, Lectures 1-12, Lab #1 (NCTS, N/AH 5th Floor; LH-A)
T 09 Feb
MARDI GRAS
13
14
F 12 Feb
F 12 Feb
8
9
BioCommunication: Cardiac and Smooth Muscle (Ch 9-B)
BioCommunication: Autonomic Nervous System (Ch 6-18)
Mr. Mouton
Mr. Mouton
15
16
17
18
T 16 Feb
T 16 Feb
F 19 Feb
F 19 Feb
8
9
8
9
Endo: Hypothalamus and Pituitary Gland (Ch 11-B)
Endo: Thyroid-Parathyroid Gland (Ch 11-C)
Endo: Adrenal Gland (Ch 11-D)
Endo: Pancreas (Ch 16-2)
Dr. Shepherd
Dr. Shepherd
Dr. Shepherd
Dr. Shepherd
19
20
21
22
T 23 Feb
T 23 Feb
F 26 Feb
F 26 Feb
8
9
8
9
Endo: Growth Hormone (Ch 11-E)
Endo: Physiology of Reproduction (Ch 17)
CV: Blood and Blood Components (Ch 12-F)
CV: Hemostasis, INR (Ch 12-F)
Dr. Shepherd
Dr. Shepherd
Dr. Potter
Dr. Potter
23
24
25
26
T 01 Mar
T 01 Mar
F 04 Mar
F 04 Mar
8
9
8
9
CV: Innate Immune Responses (Ch 18-1, 2)
CV: Acquired Immune Responses (Ch18-3)
CV: Overall Design and Hemodynamics (Ch 12-A)
CV: Electrical Activity of the Heart (Ch 12-B)
Dr. Potter
Dr. Potter
Dr. Harrison-Bernard
Dr. Harrison-Bernard
Exam #2: 8-10 AM, Tues, 08 Mar 2016, Lectures 13-24 (NCTS, N/AH 5th Floor; LH-A)
27
28
F 11 Mar
F 11 Mar
29
T 15 Mar
30
T 15 Mar
LAB #2 T 15 Mar
LAB #2 Th 17 Mar
31
F 18 Mar
32
F 18 Mar
8
9
CV: Heart as a Pump (Ch 12-B)
CV: Cardiac Cycle/Cardiac Output (Ch 12-B)
8
CV: Vasculature and Microcirculation (Ch 12-C)
9
CV: Venous Return (Ch 12-C)
1 PM ECG Lab (MDL #6)
1 PM ECG Lab (MDL #6)
8
CV: Regulation of Mean Arterial Blood Pressure (Ch 12-D)
9
CV: Review of Cardiovascular Physiology (Ch 12-E)
Page 5 of 7
Dr. Gardner
Dr. Gardner
Dr. Souza-Smith
Dr. Souza-Smith
Dr. Gardner
Dr. Gardner
Dr. Whitaker
Dr. Whitaker
No.
Day/Date TIME and TOPIC
T 22 Mar
Instructor__
NO CLASS
SPRING BREAK 22Mar16 5PM to 29Mar16 7AM
33
34
35
36
T 29 Mar
T 29 Mar
F 01 Apr
F 01 Apr
37
T 05 Apr
38
T 05 Apr
LAB #3T 05 Apr
39
F 08 Apr
40
F 08 Apr
8
9
8
9
Respiratory: Organization (Ch 13-1, 2)
Respiration: Exchange of Gases (Ch 13-3)
Respiration: Ventilation and Perfusion (Ch 13-3)
Respiration: Transport of Gases (Ch 13-4, 5, 6)
8
Respiration: Control of Breathing (Ch 13-7, 8, 9)
9
GI Function, Motility, and ENS (Ch15)
1 PM Pulmonary Function Tests (LH-C)
8
GI: Cephalic Phase of Digestion (Ch 15)
9
GI: Gastric Phase of Digestion (Ch 15)
Dr. Pellett
Dr. Pellett
Dr. Pellett
Dr. Pellett
Dr. Pellett
Dr. Shepherd
Dr. Zamjahn
Dr. Shepherd
Dr. Shepherd
Exam #3: 8-10 AM, Tues, 12 Apr 2016, Lectures 25-37, Lab #2 (NCTS, N/AH 5th Floor; LH-A)
41
42
F 15 Apr
F 15 Apr
8
9
GI: Intestinal Phase of Digestion (Ch 15)
GI: Metabolism and Energy Balance (Ch 16)
Dr. Shepherd
Dr. Shepherd
43
T 19 Apr
44
T 19 Apr
LAB#4 T 19 Apr
45
F 22 Apr
46
F 22 Apr
8
9
1
8
9
Renal: Structure, Basic Processes (Ch 14-A)
Renal: Epithelial Transport Mechanisms (Ch 14-A)
CV, Renal: Hypertension and the Kidney (LH-C)
Renal: GFR, Clearance, Intra-renal homeostasis (Ch 14)
Renal: Sodium and Potassium Balance (Ch 14-B)
Dr. Harrison-Bernard
Dr. Harrison-Bernard
Dr. Zimmerman
Dr. Harrison-Bernard
Dr. Harrison-Bernard
47
T 26 Apr
48
T 26 Apr
LAB#5 T 26 Apr
8
Renal: Water Balance (Ch 14-B)
9
Renal: Hydrogen Ion and Acid-Base Balance (Ch 14-C)
1 PM Arterial Blood Gases from a Clinical Setting
Dr. Harrison-Bernard
Dr. Harrison-Bernard
Dr. Pitt
Exam #4: 8-10 AM, Tues, 03 May 2016 Lectures 38-48, Labs #3-4 (NCTS, N/AH 5th Floor; LH-A)
FINAL EXAM #5: Time-TBA Tue, 10 May 2016
Lectures 1-48, Labs #1-4 (NCTS and LH-A)
Each student is required to complete the Moodle Syllabus Quiz prior to Friday, January 15, 2016 to attest to
your reading and understanding the content of the class schedule.
AGAIN – Your respectful and professional comments for this Course Evaluation will be used to maintain the
strengths of the course and implement your suggestions on how the course can be improved. The purpose of this
evaluation is to assist your professors in providing the best possible education to you on the functioning of the
human body as related to healthcare professionals. Although, your comments are being made in anonymity, they
will be read by the course directors, program directors, and deans of your school.
Page 6 of 7
Jan
Mon
11
Tuesday
12
Wed
13
Class
Begins
Thu
14
Friday
15
L01 Homeostasis
L02 Cell Function - Metabolism
18
19
L03 Cell Function – Membranes
L04 Diffusion – Osmosis
LAB: How To Study
20
21
22
L05 MembraneTransport
L06 Electrical Properties of Membranes
26
L07 Action and Graded Potentials
L08 Synapses and Signaling
Lab 1: Fluids, Electrolytes, Resuscitation, LH-C
02
L11 Neural Pathways and Body Movement
L12 Skeletal Muscle
27
28
29
L09 Neurotransmitters and Receptors
L10 Sensory Physiology
03
04
05
09
10
12
13
L13 Cardiac-Smooth Muscle
L14 Autonomic Nervous System
MLK
Day
25
Feb
01
08
8-10 AM: Exam #1 L01-L12; Lab #1
MARDI GRAS
Mar
15
16
L15 Endo: Hypothalamus and Pituitary
L16 Endo: Thyroid-Parathyroid
17
18
19
L17 Endo: Adrenal Gland
L18 Endo: Pancreas and Metabolism
22
23
L19 Endo: Growth Hormone
L20 Endo: Physiology of Reproduction
24
25
26
L21Hematopoiesis
L22 Hemostasis
29
01
L23 Innate Immunity
L24 Adapted Immunity
02
03
04
L25 CV: Overall Design/Hemodynamics
L26 CV: ECG and Electrical Activity
07
08
09
10
11
L27 CV: Heart as a Pump
L28 CV: Cardiac Cycle/Cardiac Output
16
17
ECG Lab,
MDL 6
18
L31 CV: Regulation of MABP
L32 CV: Review of Cardiovascular Physiology
23
24
25
8-10 AM: Exam #2 L13-L24
14
21
15
L29 CV: Vasculature and Microcirculation
L30 CV: Venous Return
Lab #2: ECG, MDL 6
22
NO CLASS
Apr
28
29
L33 Respiratory: Mechanisms of Breathing
L34 Respiratory: Lung Volumes; Gas Exchange
30
31
01
L35 Respiratory: Ventilation/Perfusion
L36 Respiratory: Gas Transport
04
05
L37 Respiratory: Control of Breathing
L38 GI: Function, Motility and ENS
Lab #3: PFT, LH-C
12
8-10 AM: Exam #3 L25-37, Lab #2-3
06
07
08
L39 GI: Cephalic phase of Digestion
L40 GI: Gastric Phase of Digestion
13
14
15
L41 GI: Intestinal Phase of Digestion
L42 GI: Metabolism and Energy Balance
19
L43 Renal: Structure and Basic Processes
L44 Renal: GFR, Clearance, Transport
Lab #4: Hypertension and the Kidney
26
L47 Renal: Water Balance
L48 Renal: H+ ion Regulation & Renal Diseases
Lab #5: ABGs, LH-C
03
8-10 AM: Exam #4 L38-L48, Lab #4-5
20
21
22
L45 Renal: Epithelial Transport
L46 Renal: Sodium and Potassium Balance
27
28
29
04
05
06
10
11
12
13
11
18
25
02
May
GOOD FRIDAY
09
Exams
Comprehensive Final Exam #5:
L01-L48, Lab #1-5
NO CLASS
Reading Day
Exams
Page 7 of 7
Exams
Final Day of Semester