AlchemistTM II:
Capacity, reproducibility and efficiency of an
high-throughput crystallization screen
preparation system.
Craig Sterling
Director of Business Development
Rigaku
Automated Protein Crystallization Platform
Phoenix RE
Experimental
Plate Setup
Minstrel HT & Gallery 700
Incubators
Imaging and Incubation
AlchemistTM II
Screen Maker
Integration Module
Including Robotic Arm, plate
and block storage, mixing
station, piercing station, and
foil and tape sealing
CrystalTrakTM
Information Flow &
Management
CrystalMationTM Features
 AlchemistTM II, Phoenix RE, MinstrelTM HT imaging system and
GalleryTM 700 incubators operate independently or as part of
the completely integrated CrystalMation system
 Allows instruments to be added over time to meet budgets
 Easy and seamless integration
 CrystalTrakTM relational database application
 Easy-to-use design is manageable by tech level personnel
 Mixing, Piercing & Sealing accessories for CrystalMationTM
system
 Low cost operation of $10 per plate including maintenance
costs and chemical costs
CrystalTrakTM
 CrystalTrak seamlessly integrates the Rigaku
Crystallization instruments, offering labs a complete
end-to-end solution
 Relational database tracks all of the necessary
information used in crystallization trials such as
chemicals, screens, protein samples, plate type
information, images, and annotations
 CrystalTrak simplifies and aids in the crystallization
process by providing tools that enable users to greatly
improve crystallization trial productivity with less user
intervention.
 One-click optimization tools
 Intuitive screen design tools
 CrystalTrak Web offers remote access to data
Custom Screen Maker – The Alchemist II
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The best accuracy in the industry
for handling stock solutions of all
viscosities, dispensing volumes as
low as 1µl using the TapperTM
technology
Produce liquid formulations
without wasting chemicals during
every cleaning, priming and wash
cycle
74 Barcoded easy to swap reagents
No tedious setup, cleaning and
maintenance
Dedicated syringe for each reagent
Easy screen design with
CrystalTrak
NEW Seal-tight BirdFeedersTM
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New threaded cap, Seal-tight design
Long-term storage of stock solutions on deck
Works with standard stock solution bottles
Barcode Tracking of birdfeeders and stock solutions
Autoclave-able design
Easy-pour design for replacement of stocks
Four different stock solution sizes
20ml in Birdfeeder with cap
Good for expensive stocks and additives
125ml Nalgene bottles
250ml Nalgene bottles
Three Syringe sizes (Eppendorf)
100ul
1ml
10ml
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Alchemist II
Automated Protein Crystallization Platform
Phoenix RE
Experimental
Plate Setup
Minstrel HT & Gallery 700
Incubators
Imaging and Incubation
AlchemistTM II
Screen Maker
Integration Module
Including Robotic Arm, plate
and block storage, mixing
station, piercing station, and
foil and tape sealing
CrystalTrakTM
Information Flow &
Management