Chapter Twelve Pregnancy and Birth Issues Associated with Pregnancy and Birth Fertility Assisted Reproduction A Healthy Pregnancy Health Care During Pregnancy Problems in the Pregnancy Childbirth Problems During Birthing Postpartum Parenthood Self Reflection Exercise Do you want to have children? Why or why not? If you do desire children, at what age would you like to have your first child? How many children would you like to have? Why? How would you like to have your children spaced? Why? Would you rather have a boy or girl first? How many boys and girls would you like to have? Why? What would you like to name your children? Why? Would you dress your girls in pink and boys in blue? Why or why not? How would your parents feel about grandchildren? Deciding Whether to Have Children What is your response to these two couples? Fertility Conception Early Signs of Pregnancy Pregnancy Testing Sex Selection Conception: The Incredible Journey Our bodies are designed to promote pregnancy During ovulation: A woman’s sexual desire peaks A mucus plug in the cervix disappears Cervical mucus thins & creates gaps that vibrate with the sperm to aid motility and trap defective sperm; filters bacteria from semen Female orgasm pushes semen to the uterus and toward the Fallopian tubes Semen thickens upon ejaculation to stay in the vagina for 20 minutes to aid sperm travel Conception: The Incredible Journey The ovum can live for 24 hours Sperm can live for 72 hours; less than 1% can live up to one week Pregnancy may occur a few days before or after ovulation The ovum may release chemicals to signal its location If a sperm reaches the ovum, it wriggles violently Conception: The Incredible Journey Only one sperm fertilizes an ovum by secreting a chemical that makes a hole in the ovum coating Immediately the ovum coating changes & does not permit further sperm from entering Fertilization takes about 24 hours, usually in the ampulla Zygote – a fertilized ovum Conception: The Incredible Journey About 12 hours after fertilization, the first cell division occurs & the blastocyst divides every 12 to 15 hours as it travels towards the uterus 3-4 days after conception, it enters the uterus & absorbs nutrients from endometrial glands 6th day after conception, a uterine chemical dissolves the blastocyst coating, allowing implantation into the uterine wall, typically the upper portion Conception: The Incredible Journey After implantation, the blastocyst divides into two layers, the endoderm & ectoderm, followed shortly by the mesoderm Embryo – developing cell mass of 2-8 weeks Amnion – membrane covering the embryo that fills with protective fluid Placenta – attached to the uterine wall, it aids the fetus in respiration, nutrition, excretion Umbilical cord – connects fetus to placenta Conception: The Incredible Journey Multiple births occur in 1 out of 50 couples Fraternal twins – two ova are released & fertilized; 2/3 of twins are fraternal; dizygotic May be inherited from the mothers More likely with women over 30 Identical twins – single zygote divides into 2 separate zygotes; monozygotic Siamese twins – fail to completely separate Pregnancy Early Signs of Pregnancy Missing a period, or maybe some spotting Breast tenderness, frequent urination, food aversions Morning sickness 50-80% of pregnant women experience nausea &/or vomiting, any time of the day Due to increased estrogen & progesterone irritating the stomach lining May protect the fetus from illness Pregnancy Testing: Confirming the Signs Over-the-counter pregnancy tests Can be less expensive at a clinic The tests measure for human chorionic gonadotropin (hCG), which is made by placental cells Detection in blood or urine can occur 8-9 days after ovulation hCG levels peak in the 2nd & 3rd months Pregnancy Testing: Confirming the Signs May be inaccurate if tested too soon or after the 12th week False positives may occur with kidney disease, kidney infection, overactive thyroid, large doses of tranquilizers, aspirin, antidepressants, anticonvulsants Radioimmunoassay (RIA) blood tests are the most accurate, can detect hCG within a few days after conception Pregnancy Testing: Confirming the Signs Due date – calculated from the first day of the last menstrual period Naegeles rule – subtract 3 months from the first day of the last period and add 7 days for a single birth Rule is most accurate for women with 28-day cycles Sex Selection Sex Selection: Myth and Modern Methods More male babies are born each year Male fetuses have higher rates of spontaneous abortion or die before birth There are many cultural myths for choosing and knowing the gender of an unborn child There are medical techniques that can aid in choosing and determining fetal sex Sex Selection: Myth and Modern Methods Microsorting can separate the X and Y sperm, which is then artificially inseminated Male conception is 50-70% accurate Female conception is 50-90% accurate Embryos can be tested and the desired sex embryo then implanted Amniocentesis involves removal of amniotic fluid through a needle during week 16 or 17; detects chromosomal abnormalities & gender Sex Selection: Myth and Modern Methods Controversy surrounds gender selection Male children are typically valued over females in other countries because They typically care for their aged parents Girls require dowries to be paid at their marriage Males carry on the family name Female infanticide is a problem in rural India and in China Assisted Reproduction What is Assisted Reproduction? Assisted Reproductive Options What Is Assisted Reproduction? Infertility – the inability to conceive, or impregnate, after one year or regular sexual intercourse without the use of birth control Infertility may be diagnosed after only 6 months for women over 35 years About 20% of U.S. couples of reproductive age are infertile; 8-10% in developed countries What Is Assisted Reproduction? Negative emotions are often experienced with the frustration of infertility Women tend to be more committed to finding a solution than their partners Motherhood mandate – there is a problem with a woman if she does not care for a child Some reproductive problems can be reduced with changing lifestyles, reducing stress, avoiding strenuous exercise, average weight What Is Assisted Reproduction? 70% of the time the problem can be found in one of the partners 40% female (ovulation disorders, blocked Fallopian tubes, endometriosis, uterine fibroids, uterine structure, STIs) 30% male (lack of sperm, reduced or malformed sperm production, STIs) 20% of the time it is a combined problem 10% the reason is unknown Assisted Reproductive Options Fertility Drugs Surgery Artificial Insemination In Vitro Fertilization Gamete Intra-Fallopian Tube Transfer Zygote Intra-Fallopian Tube Transfer Zonal Dissection Intracellular Sperm Injections Oocyte and Embryo Transplants Surrogate Parenting Assisted Reproductive Options Artificial methods of conception are used by those experiencing infertility, those without a partner, and gay couples These methods may also cause further stress because they are expensive, time consuming, and may not work Type of treatment depends on length of infertility, the woman’s age, & likelihood of conceiving without treatment Fertility Drugs Hormonal irregularities may need to be treated with fertility drugs The drugs increase ova production, which increases the possibility of multiple births Possible increased risk of breast and ovarian cancer Surgery Structural abnormalities in the cervix, vagina, Fallopian tubes, or endometrium may be surgically corrected Surgery can also be used to remove blockage of the vas deferens or epididymis Artificial Insemination Insertion of sperm into the vagina, cervix, uterus, or Fallopian tubes without intercourse Ejaculated sperm is collected via masturbation by the partner or a donor Sperm banks can freeze treated and washed sperm for up to 10 years Donor catalogs are available, and sperm is sent to a physician Fertility drugs are often used in combination In Vitro Fertilization “Test-tube babies” are conceived in a petri dish, then implanted in the uterus Fertility drugs encourage the release of many ova and 4-6 are retrieved, although drugs aren’t always used The ova are put in a dish and mixed with sperm; the zygotes are implanted Only 5-30% implant, so many are often implanted Gamete Intra-Fallopian Tube Transfer Ova and sperm are placed in the Fallopian tube before conception Fertility drugs and sperm washing are also used Higher implantation rate than in vitro fertilization Zygote Intra-Fallopian Tube Transfer Fertilization occurs outside of the body The zygote is placed in the Fallopian tube, allowing it to implant naturally Higher implantation rates than in vitro, but not higher than gamete intra-fallopian tube transfer Zonal Dissection A microscopic hole is drilled into the ovum or a chemical is used to dissolve the outer shell of the ovum Problem is that several sperm may enter at the same time and cause developmental problems Intracellular Sperm Injections A single sperm is injected into the center of an ovum Helps if sperm counts are low or have low motility 52% pregnancy rates The ovum can be damaged Possible increased risk of genetic defects Oocyte and Embryo Transplants For women who cannot produce healthy ova Eggs and embryos from other women may be donated 25-33% birth rates Fertility drugs are necessary to synchronize both women’s menstrual cycles High success rates Surrogate Parenting Another woman’s uterus is used to carry a pregnancy Ova and sperm are fertilized outside of the body and the zygote is implanted in the gestational carrier If the surrogate’s ova is used, the carrier is called a surrogate mother Other Options Embryos and sperm can be frozen for later use Often used by those undergoing cancer treatment that want to have children Sometimes sperm do not survive the thawing Not all embryos survive the freezing and thawing It is much more difficult to freeze an ova, they are very vulnerable to chromosomal damage A Healthy Pregnancy The Prenatal Period: Three Trimesters The Father’s Experience The Prenatal Period: Three Trimesters Pregnancy lasts 40 weeks, and each trimester is about 12-15 weeks long Video: “The Miracle of Life” First Trimester 1-13 weeks The fetal heart forms and pumps blood by the end of the first month, as the circulatory system is the first to function Other systems begin to develop: nervous, digestive, urinary, reproductive, appendages Liver, kidneys, intestines, lungs begin developing by the end of this trimester At the end, the fetus is ½ ounce & 3 inches An embryo at 7 to 8 weeks. This embryo is approximately 1 inch long. First Trimester The woman’s heart pumps more blood, body gains weight, thyroid gland grows, lungs and digestive system work harder Increases in estrogen & progesterone can cause: fatigue, breast tenderness, constipation, increased urination, nausea, vomiting, food cravings, smell sensitivity Ultrasound can detect the fetal heartbeat and image as soon as 5 ½ - 6 weeks Second Trimester 14-28 weeks Reflexes and tooth buds develop Ultrasound may pick up gender around 20-22 weeks Movements can be felt by the mother Lanugo and vernix cover the fetus to protect it from amniotic fluid At the end, the fetus is 1¾ pounds & 13 inches At five months, the fetus is becoming more and more lively. It can turn its head, move its face, and make breathing movements. This fetus is approximately 9 inches long. Second Trimester In the mother, nausea subsides Fatigue may continue, appetite increases, and other signs show: heartburn, edema, vaginal discharge, skin pigmentation, muscle cramps, varicose veins, hemorrhoids Increased blood supply & restriction of veins Positive time for mother, positive emotions, increased sex drive & satisfaction, maternity clothes, feel the baby moving Third Trimester 28-40 weeks The fetus develops fat deposits, hiccups The fetus can suck its thumb and react to light, pain, sounds 8th month most organ systems are well developed, though the brain continues growing At the end, the fetus is 7½ pounds & 20 inches A fetus at nine months, ready for birth. Third Trimester Many symptoms from the second trimester continue and increase in frequency, as blood supply is large, and there is a large weight gain Backaches, leg cramps, sleep problems, shortness of breath, and Braxton-Hicks contractions may occur Colostrum may be secreted by the breasts in preparation for breast feeding The Father’s Experience Upcoming parenting and changes in their partner can make a man feel vulnerable Joy, anticipation, stress, and anxiety are all common feelings Fathers are allowed and encouraged to be in U.S. delivery rooms Health Care During Pregnancy Exercise and Nutrition Drugs and Alcohol Pregnancy in Women over 30 Sex during Pregnancy Exercise and Nutrition Exercise during pregnancy should not exceed prepregnancy exercise levels Light exercise is suggested; water exercise Although the implanted embryo is difficult to dislodge, some sports are to be avoided: water skiing, horseback riding, racquet sports, scuba diving, contact sports Avoid reduced blood flow to the uterus Drink a lot of water Exercise and Nutrition Increased protein, iron, calcium, folic acid, and vitamin b6 are needed in pregnancy 300 more calories per day are also necessary for a healthy pregnancy Poor nutrition may cause low birth weight babies and problems for the infant, such as cardiovascular disease, hypertension, and diabetes Prenatal vitamins are often recommended Drugs and Alcohol Many substances should be avoided during pregnancy to avoid fetal defects: caffeine, nicotine, alcohol, marijuana, other drugs Fetal Alcohol Syndrome (FAS) – an undersized and mentally deficient infant due to a mother drinking heavily during pregnancy 11% of U.S. women smoke while pregnant, increasing risk of spontaneous abortion, low birth weight, low iron, brain damage, & prematurity Drugs and Alcohol Pregnancy in Women over 30 An increasing number of women are delaying childbearing for educational & career goals Delayed pregnancy risks: spontaneous abortion, first-trimester bleeding, low birth weight, increased labor time, c-section Chromosomal abnormalities increase for women over 30 and men over 55 Sharp decline in fertility for women after 40 Sex during Pregnancy Sex is safe for most with uncomplicated pregnancies, as is orgasm, until the last few weeks of pregnancy Both partners may have changes in sexual desire Fear of injuring the fetus is often cited as a reason for decreased sexual interest Some positions are difficult and this restricts the variety of intercourse Problems in the Pregnancy Ectopic Pregnancies Spontaneous Abortions Chromosomal Abnormalities Rh Incompatibility Toxemia Ectopic Pregnancies The zygote implants outside of the uterus 2% of U.S. pregnancies are ectopic 97% of ectopic pregnancies occur in the Fallopian tubes 3% occur in the cervix, ovaries, abdomen Increased risk for ectopic pregnancies if had STIs, a smoker, previous ectopic pregnancy Symptoms: abdominal pain, cramping, bleeding, nausea, dizziness, fainting In an ectopic pregnancy, the fertilized ovum implants outside the uterus. In most cases, it remains inside the Fallopian tube. Spontaneous Abortions A natural termination of a pregnancy before fetal survival; a miscarriage 10% of diagnosed pregnancies miscarry 20-40% are miscarried before diagnosis Most miscarry because of a chromosomal abnormality Other reasons: uterine capability, stress, poor nutrition, drugs, pelvic infection, defective sperm Spontaneous Abortions Symptoms: bleeding, cramps, lower back pain Menstruation usually returns in 3 months Future pregnancies can be normal Chromosomal Abnormalities Chromosomal abnormalities may be detected by amniocentesis, chorionic villus sampling, & maternal-serum alpha-fetoprotein screening CVS – piece of chorionic tissue is tested as early as 10-11 weeks Risk of miscarriage & limb damage MSAFP – blood test at 16-18 weeks Blood samples can also be drawn from the umbilical cord Chromosomal Abnormalities Risk for abnormalities increases with a woman’s age Most common is Down syndrome, where there is an extra 21st chromosome 1/1000 live births Mother’s Age and Risk of Chromosomal Abnormality Rh Incompatibility Rh factor – natural part of red blood cells in some people If the mother is Rh- & baby is Rh+ (from the father), fetal blood that comes in contact with her blood during delivery (not pregnancy) will cause her to create antibodies This can affect future pregnancies Rhogam is given to her after delivery to prevent the formation of antibodies Toxemia 6-7% of women experience toxemia, or preeclampsia in the last 2-3 months Symptoms: rapid weight gain, fluid retention, increased blood pressure, protein in the urine If not controlled, eclampsia can result, which includes convulsions, coma, & in 15% of cases, death Primarily affects those that lacked good prenatal care Childbirth Preparing for Birth Birthplace Choices Inducing the Birth Birthing Positions Stages of Childbirth Childbirth Normal birth occurs 3 weeks before to 2 weeks after the due date 4% are born on the due date in the U.S. Early deliveries more likely if female fetus, mother exercised during pregnancy, mother has shorter menstrual cycles More babies born between July & October and between 1 & 7 a.m. Pitocin or nipple stimulation may hasten labor Preparing for Birth Lamaze & similar birthing classes increase knowledge and reduce anxiety They teach what to expect and how to control pain with breathing and massage Anxiety during labor increases pain, discomfort, & fatigue Engagement – fetus moves to head down position a few weeks before birth 97% of the time Birthplace Choices 80% of births worldwide occur at home Home birth is as safe as hospital delivery for low-risk pregnancies Most babies in the U.S. are born in hospitals Some hospitals have more comfortable birthing centers available Inducing the Birth Drugs can be given to induce, and hasten the progression of, labor May create more painful and prolonged contractions Birth may occur a few hours to days after induction In 1998, 19% of U.S. births were induced Reasons: past due date, avoid having a large baby, labor is not progressing, scheduling Birthing Positions In the U.S., most hospitals use a semireclined position with feet in stirrups One possible reason for this position is that it is easier for doctors A woman on her hands & knees or who is squatting widens her pelvis & cervix and using gravity to aid in the delivery Underwater birth can make labor less painful for women and less traumatic for infants Stages of Childbirth Stage One: Cervical Effacement & Dilation Stage Two: Expulsion of the Fetus Stage Three: Expulsion of the Placenta Stage One Can last 20 minutes to 24 hours This stage is longer in first births Cervix dilates – the os goes from 0 to 10 cm Cervix thins out (effacement) Early labor – Amniotic sac ruptures Cervix dilates to 4-5 cm Contractions last 30-60 seconds with 5-20 minute intervals Stage One Active labor Contractions last 1+ minutes, are more intense, and occur every 1-3 minutes Cervix dilates to 8 cm Transition Very intense, long, & frequent contractions Cervix dilates to 10 cm Fetus moves to pelvic base, creating an urge to push Stage One The woman produces endorphins, pain reducing hormones Pain medications may also be given, though they may cause drowsiness or nausea and may affect the fetus Relaxation techniques, breathing, & acupuncture have been used to provide relief Fetal monitoring checks for fetal distress through the abdomen or the fetus’s scalp Stage Two Contractions become less intense, last 60 seconds every 1-3 minutes Episiotomies are performed in 40% of U.S. births, though they are controversial While pushing during contractions, the baby’s head appears (crowning) When the face appears, mucus & fluid are removed from the mouth & nostrils Stage Two Umbilical cord is cut after the first breath Eye drops are put in the baby’s eyes to prevent bacterial infection Newborn is placed on the mother’s chest to begin bonding Apgar test may be performed to check the well being of the infant Stage Three Contractions continue after the birth The placenta (after-birth) is expelled about 30 minutes after the birth All of the placenta must be expelled If there was an episiotomy or tearing, the woman is sewn up Problems During Birthing Premature Birth Breech Birth Stillbirth Cesarean Section Delivery Premature Birth: The Hazards of Early Delivery Premature births occur before the 37th week 8% of U.S. births are premature Prematurity increases the risk of defects & infant mortality Reasons: early labor or rupture of amniotic sac, maternal or fetal problems, multiple fetuses, smoking during pregnancy, alcohol & drug use, poor nutrition or weight gain, infections, teenage pregnancy, heavy labor Breech Birth: Feet First into the World Breech position – the fetus has the feet or buttocks towards the cervix Occurs in 3-4% of births Some doctors can rotate the fetus for vaginal delivery, or even deliver it safely in this position Cesarean section may be performed for the safety of the baby and mother In 3% to 4% of births, the fetus is in the breech position, with feet and buttocks against the cervix. Stillbirth: Sad Circumstance Stillbirth - a fetus that dies after 20 weeks Causes: birth defects, placental problems, umbilical cord accidents, infections, maternal diabetes or high blood pressure Typically the woman goes into labor about 2 weeks after the fetus has died Cesarean Section (C-Section) Delivery The baby is delivered through an incision in the abdominal wall 21% of U.S. deliveries, which is an increase from a few decades ago Reasons for the increase: women waiting longer to have children, easier & safer procedure, fear of malpractice suits Cesarean Section (C-Section) Delivery Necessary when: baby is too large, woman cannot push, placenta previa, cervix does not fully dilate, fetal distress Procedure occurs in an operating room under general anesthesia or an epidural Lasts 20-90 minutes Requires longer hospital stay Can become pregnant and deliver vaginally in the future Postpartum Parenthood More Physical Changes for the Mother Postpartum Psychological Changes Sexuality for New Parents Breast-Feeding the Baby More Physical Changes for the Mother 6 weeks after birth, the uterus returns to its original shape This may be sooner in breast-feeding women Bloody discharge lasts for at least a week after delivery May be advised to take sitz baths if an episiotomy or tear occurred during delivery Postpartum Psychological Changes Most women are exhausted and experience minor sadness due to increased responsibility, physiological changes, exhaustion, hormonal changes such as a sudden drop in progesterone Postpartum depression – severe case of sadness with crying spells & anxiety Postpartum psychosis – most severe cases that include mental disturbances Sexuality for New Parents Most are advised to wait 6 weeks before resuming intercourse to insure no infection occurs Sex may be safe in 2 weeks if there was an uncomplicated vaginal delivery Cesarean section incisions heal in about 2 weeks and intercourse is safe at this time 3 months postpartum, most return to original levels of desire & excitement Breast-Feeding the Baby Infant shows a rooting reflex within an hour after birth, signaling hunger Sucking triggers flow of milk from the breast through receptors in the nipples These receptors signal to the pituitary to produce prolactin Oxytocin is also produced, which helps contractions of the uterus to shrink the uterus Breast-Feeding the Baby Colostrum – the fluid produced by the breasts in the first few days of breastfeeding that strengthens the baby’s immune system American Academy of Pediatrics recommends exclusive breast-feeding for 6 months, & continued for at least one year World Health Organization recommends exclusive breast-feeding for 4-6 months, & continued for at least 2 years Breast-Feeding the Baby At 6 months, only 29% of American women breast-feed Natural age of weaning is 2 1/2 years, and the maximum is 6-7 years Class Exercise: Discuss Handout 12.2