Basic Physics of Ultrasound Beth Baughman DuPree M.D. FACS Medical Director Breast Health Program Holy Redeemer Health System 2011 Financial Disclosures Faculty/Consultant Ethicon Breast Care Speaker- Myriad Genetics Consultant Precision Therapeutics Faculty- CME at Sea Breast Ultrasound Certification Stereotactic Biopsy Certification Mastery of Surgery Program APBI Registry www.breastsurgeons.org The Changing World of Breast Care Precision Therapeutics Chemo Fx Assay BCT DCIS MR Mastectomy BCT Lump/ALND XRT DCIS CHEMO N - SLN WHOLE BREAST XRT OPEN SURGICAL BX BRCA TESTING BLN APBI B-39 PEM BX STEREO MIBB US MIBB 1980 1990 ONCOTYPE 2000 CONSENSOUS ST MRI MIBB 2010 Basic Principles Sound waves are mechanical waves that require a medium through which to propagate Sound cannot travel through a vacuum Different materials have different acoustic properties Varies the ability to transmit sound waves Varies the ability to reflect sound at interfaces Frequency The number of cycles completed per second. 1 cycle per second is called Hertz (Hz) •Humans hear frequencies •Sound above the level of in the range of 20Hzhuman hearing is called 20,000Hz ultrasound Frequency Diagnostic Ultrasound is measured in mega hertz (MHz) mega means millions Imaging transducers are named by their operating frequency Frequency Range - 2.25 MHz-20 MHz 5 MHz transducer = 5 million cycles/sec. Sound Source Incident Transmitted Reflected MEDIUM 1 MEDIUM 2 Acoustic Interface Reflection Soft Tissue (1540 m/s) Fat (1459 m/s) Acoustic interface / Acoustic Mismatch Soft Tissue (1540 m/s) Bone (4080 m/s) Getting an Image The heart of ultrasound is the transducer Piezo - electric effect Piezo-Electric Effect The crystal is mounted on a rotational axis It is driven by an electric motor A sound pulse is transmitted and received Results in a specific focal zone Some transducers contain several crystals Hence 8-14mHz probes have several crystals The Transducer Converts electrical energy into sound Components: Piezoelectric crystal Dampening material Matching layer covers crystals The Transducer 3.5 MHz Thicker crystal produces bigger sound waves. 7.5 MHz Thinner crystal produces smaller sound waves. The Transducer 3.5 MHz 7.5 MHz The LOWER the frequency the better the penetration The HIGHER frequency the less the penetration Bigger, Stronger Smaller, weaker The Transducer Short pulses of sound are sent (transmits) into the body and then the transducer listens for the returning signals (receives). The ultrasound system processes the returning signals into images that are displayed on the ultrasound monitor Transmits Waits Receives Linear Array Transducer Electronic Linear-Array Transducer Parallel arrangement of the crystals Two-dimensional, rectangular image Time delay between successive crystal firing can be varied Directing and focusing the beam Gray Scale B-Mode Ultrasound Soft Tissue Fat Soft Tissue Bone Soft Tissue Cyst Grayscale Imaging Propagation speed is how fast the sound travels through a medium. The system keeps track of when the pulse is sent and when the echo returns and places the pixel at a depth represented by the time difference. Grayscale Imaging The strength of the returning echoes also depends on the differences in the acoustic impedance between various structures. Acoustic impedance relates to tissue density. The greater the difference in density between two structures, the stronger the returning echo Examples: different: aorta and liver same: kidney and liver Grayscale Imaging Attenuation: A decrease in the strength of the sound wave as it passes through tissue and further into the body. Acoustic Impedance: The resistance of the sound wave traveling through tissue Each tissue has its own acoustic impedance due to the density of the tissue. Through Transmission There is no attenuation of the sound wave traveling through the tissue. Grayscale Imaging WHITE DOTS = STRONG = e.g., bone BLACK DOTS = NO reflections = e.g., fluid GRAY (different shades) = WEAKER reflections Grayscale Imaging The strength of the returning echo is directly related to the angle at which the ultrasound beam strikes an interface. The more perpendicular the ultrasound beam, the stronger the returning echo. Echogenicity fat - equivalent hypoechoic isoechoic hyperechoic anechoic Echogenicity Anechoic Hypoechoic Isoechoic Hyperechoic Echogenicity Anechoic Hypoechoic Isoechoic Hyperechoic Echogenicity Anechoic Hypoechoic Isoechoic Hyperechoic Echogenicity Anechoic Hypoechoic Isoechoic Hyperechoic Resolution Clarity of picture Ability of equipment to detect 2 separate reflectors in tissue and to display them as 2 separate reflectors on the monitor without merging them. Image Resolution Types of Resolution The ability to identify structures very close together: Axial Ability to identify structures that are one in front of the other Lateral Ability to identify structures that are side by side Temporal Ability to accurately locate a moving structure Spatial Ability to display very small structures in their correct anatomic location. Axial Resolution 3.5MHz 7.5 MHz The shorter the pulse, the better the axial resolution Increasing the frequency increases axial resolution Characteristics of Sound Frequency Sound Sound Axial Frequency Penetration Resolution High Low Lateral Resolution Very important for ultrasound guidance with needles/probes A transducer with a large surface area will resolve better in the lateral dimension “Fine-tuning” the Image Gain=Volume GAIN Control Controls the brightness of the whole image Not enough gain Too much gain Time Gain Compensation (TGC) Depth Gain Compensation • Compensates for tissue attenuation • Controls the brightness in portions of the image • Distributed over depth Poor TGC adjustment Good TGC adjustment Focus Focal Zones • Decreases the beam diameter • Adjustable by operator. • Place in area of interest Focus the Image Focal Zones Image of a solid mass with the focal zone placed incorrectly The focal zone depicted by the caret is at the bottom of the image. Focal Zones Image of the same solid mass with the focal zone placed correctly The focal zone depicted by the caret is at the top of the image near the lesion. Depth Depth is patient dependant Depth is transducer dependant Operator controlled Deep Increase depth Demonstrate shadowing Superficial Decrease depth Image Artifacts Used to decide if structures are fluid-filled, solid or a combination. Acoustic Shadowing Acoustic Enhancement Acoustic Shadow = decrease in the intensity of the echoes behind the attenuating structure Acoustic Enhancement = increase in the intensity of the echoes behind the structure Artifacts and Aberrations Shadowing Enhancement Reverberation Edge effect Shadowing Artifacts and Aberrations Shadowing Enhancement Reverberation Refraction Edge effect Posterior enhancement is not proof of a cyst. Artifacts and Aberrations Shadowing Enhancement Reverberation Refraction Edge effect Reverberation First Reflector Second Reflector Artifacts and Aberrations Shadowing Enhancement Reverberation Refraction Edge effect Incident Beam Reflected Beam Medium 1 Medium 2 Transmitted Beam Snell’s Law Artifacts and Aberrations Shadowing Enhancement Reverberation Refraction Edge effect Edge effect B C R S Summary of Ultrasound Physics Frequency-”resolution” Gain-”volume” Focus-”beam adjustment” Depth-”field of view”