Market for Hospital Services Outline Hospital Industry Structure Hospital Conduct Industry Performance Hospital Industry Structure Is the hospital market competitive? Competitiveness depends on: number of hospitals barriers to entry demand/ number of buyers types of services/technology asymmetric information (patients & hospitals) U.S. Institutional Setting Hospital classification Community hospitals Physician-owned specialty hospitals Teaching hospitals Private for profit, private not-for-profit, public not-for-profit Community Hospital Characteristics 1970-2007 Measure No. of hospitals Beds (thousands) Beds per 1,000 population Admissions (thousands) Admissions per 1,000 population Resident U.S. Population Average length of stay (days) Percent occupancy Outpatient visits (millions) Outpatient visits per admission Outpatient surgeries as a percent of total Cost per day ($) Cost per stay ($) 1970 5,859 848.2 4.17 29,252 144.0 1980 5,904 992.0 4.38 36,143 159.6 1990 5,420 929.4 3.73 31,181 125.4 2000 4,915 823.6 2.93 33,089 117.6 2007 4,897 800.9 2.65 35,346 117.2 203.2 7.7 226.5 7.6 248.7 7.2 281.4 5.8 301.6 5.5 78.0 133.5 75.4 202.3 66.8 301.3 63.9 521.4 66.6 603.3 4.6 5.6 9.7 15.8 17.1 - 16.3 50.5 62.7 62.7 74 605 245 1,851 687 4,947 1,149 6,649 1,696 9,337 Source: Health, United States, 2009: With Chartbook on Trends in the Health of Americans, Tables 104, 117, 118 and 136. Community Hospitals by Ownership Type Year Number of hospitals 1975 1980 1990 2000 2007 5,875 5,830 5,384 4,915 4,897 Year Number of beds (thousands) 1975 1980 1990 2000 2007 941.8 988.4 927.4 823.6 800.9 For Profit No. % 775 730 749 749 873 13.2 12.5 13.9 15.2 17.8 For Profit No. % 73.5 87.0 101.4 109.9 115.7 7.8 8.8 11.0 13.3 14.4 Not-for-Profit No. % 3,339 3,322 3,191 3,003 2,913 56.8 57.0 59.3 61.1 59.5 Not-for-Profit No. % 658.2 692.5 656.8 583.0 553.7 69.9 70.0 70.8 70.8 69.1 Government No. % 1,761 1,778 1,444 1,163 1,111 30.0 30.5 26.8 23.7 22.7 Government No. % 210.2 208.9 169.2 130.7 131.4 Source: Health, United States, 2009: With Chartbook on the Health of Americans, Table 115, 200. 22.3 21.2 18.2 15.9 16.4 Size Distribution of Community Hospitals Bed Size Category 0-24 25-49 50-99 100-199 200-299 300-399 400-499 500 and over 1970 6.8% 22.6 25.4 21.8 10.1 6.1 3.2 4.0 Percentage of Hospitals in Each Bed Size Category 1980 1990 2000 4.4% 17.7 5.1 23.5 12.3 7.1 4.6 5.4 4.2% 17.4 23.5 24.3 13.7 7.6 4.1 5.3 5.9% 18.5 21.5 25.1 13.3 6.9 3.7 5.0 2007 7.3% 21.9 19.8 22.1 12.5 7.0 3.9 5.3 Source: Health, United States, 2009: With Chartbook on the Health of Americans, Table 115. Hospital Industry Structure # of hospitals declined 17% # of beds declined 15% Median size: 150 beds Short-term stays (< 7 days) Outpatient visits up dramatically Nonprofit For-profit State & Local 60% 18% 22% Area Hospitals Marietta Memorial Selby CamdenClark St. Joseph’s Type NFP NFP NFP NFP Beds 199 25 375 325 Physicians 90+ na 150+ 160+ 1200+ 250+ 1300+ na Staff Barriers to Entry Certificate of Need (CON) laws Required in certain states to open a hospital (designed to limit excess capacity) Economies of scale LRAC of community hospital reach minimum around 175-200 beds Multi-hospital system Learning By Doing Over time, higher cumulative output, more experience leads to lower costs, higher quality. Mergers Horizontal: merger of firms in same market Exploit EOS Reduce administrative costs Improve customer access to information Vertical: mergers of firms in upstream and/or downstream markets Advantages Solves the agency problem Lowers transactions costs Ensures supply of input Disadvantages Monopoly power Insurers & hospitals (Allina) Insurers & physicians (Kaiser) Physicians & hospitals (PHO) Hospital Conduct Large # of sellers and low entry barriers promote competition: Higher output and quality Lower price However, the hospital market has important differences: Hospitals don’t necessarily maximize profits Role of Non-Profit Hospitals Government is a major payer Prices not set competitively Consumer less likely to shop around Insurance and asymmetric info Empirical Evidence Studies prior to 1990 support the idea of a “Medical Arms Race” Regions with more competition have: More excess bed capacity Larger # of duplicate specialized services After 1990, increased competition led to: Lower costs and improved quality Models of Hospital Behavior Profit Maximization Utility maximizing models Physician-control models Hospital Income Flows Sources of Funds Uses of Funds Patients self pay 3% Private Insurance 36% Philanthropy 5% Medicare 29% Medicaid 20% Other government Labor Professional fees Supplies, other Depreciation and interest 53% 5% 34% 8% 7% 100% 100% Pricing Practices in Medicine Hospital Expenses by Ownership Type Year 1980 1990 2000 2007 Year 1980 1990 2000 2007 Expenses per Inpatient Day For Profit Not-for-Profit Government $ 257 752 1,057 1,536 $ 246 692 1,182 1,776 $ 239 634 1,064 1,472 Expenses per Inpatient Stay For Profit Not-for-Profit Government $1,676 4,727 5,642 7,823 $1,902 5,001 6,717 9,593 $1,750 4,838 7,106 9,523 Source: Health, United States, 2009: With Chartbook on the Health of Americans, Table 136. Hospital Price Inflation in the US Year 1990 2000 2001 2002 2003 2004 2005 2006 Annual Percent Change CPI Hospital Inflation Services 4.7 9.9 2.5 4.2 2.8 6.6 1.6 8.7 2.3 7.3 2.7 5.9 3.4 5.3 3.2 6.5 Source: Health, United States, 2007: With Chartbook on the Health of Americans, Table 120. Pricing Practices in Medicine Price discrimination Cost shifting From Medicare patients to private patients Charges and discounts for diagnostic bilateral mammogram Hospital (Location) Official charge Medicaid Medicare HMOs, Health plans Policy on Uninsured UCLA Medical Center (Los Angeles) $460 $127 $90 Up to $242 Gives discounts based on individual's ability to pay, says CFO Sergio Melgar Oregon Health & Science University (Portland) $240 $65 $59 Average $128 Works with uninsured patients to help them find financial aid; offers sliding scales, payment plans Jamaica Hospital (Queens, N.Y.) $351 $50 $96 $40 to $78 Has sliding fee scales for uninsured, says CEO David Rosen Johns Hopkins Hospital & Health System (Baltimore) $261 $156 $173 $186 Grinnell Regional Medical Center (Grinnell, Iowa) $285 $73 $79 $119 to $190 State regulation of charges reduces disparity between bills to insured and uninsured Works with uninsured to set a payment schedule Source: Lucette Lagnado, “A Young Woman, An Appendectomy, And a $19,000 Debt,” Wall Street Journal, March 17, 2003, A1. Pricing Practices in Medicine Price discrimination Cost shifting From Medicare patients to private patients Problem Set #6 Market for Pharmaceuticals Pharmaceutical Industry Pharmaceuticals account for 12% of healthcare spending Drug companies spend 14% of revenues on R&D Industry Structure Basic research--supported by NIH labs and grants to universities Applied research--development of marketable drugs 284 new drug approvals from 1990-99: 265 from industry 9 from government 10 from academia The World's Top-Selling Drugs, 2008 Drug Purpose Maker Global Sales ($billions) Annual Growth Lipitor (2011) Lowers cholesterol Pfizer $13.7 -0.9% Plavix (2011) Blood-thinner Bristol-Myers Squibb and Sanofi-Aventis $ 8.6 16.9% Nexium (2015) Treats ulcers AstraZeneca $ 7.8 7.8% Advair (2010) Treats asthma GlaxoSmithKline $ 7.7 7.0% Enbrel (2012) Treats arthritis Amgen/Wyeth $ 5.7 5.6% Seroquel (2011) Anti-psychotic AstraZeneca $ 5.4 14.9% Zyprexa (2011) Anti-psychotic Eli Lilly $ 5.0 -1.8% Remicade (2018) Treats arthritis & Crohn’s Disease Centocor $ 4.9 14.0% Singulair (2012) Treats asthma Merck $ 4.7 3.1% Lovenox (2007) Treats deep vein thrombosis Sanofi-Aventis $ 3.8 8.9% http://pharmexec.findpharma.com/pharmexec/Special+Reports/2009-PharmExec-Top-50/ArticleStandard/Article/detail/597526 Top 10 Global Pharmaceutical Companies R&D Process in Pharmaceuticals Kefauver-Harris Amendment (1962) Thalidomide scare (1957-61) Established safety and efficacy standard Drug advertising must disclose side effects R&D Process $55 billion spent by US pharma in 2006 DiMasi et al. (2003): average out-of-pocket cost for a new approved drug is $403m (and fully capitalized cost is $802m) R&D Process New Drugs Introduced into the US Market 1940-1990 Country of Origin Number of New Drugs Percentage 764.0 60.4 Switzerland 89.0 7.0 United Kingdom 81.5 6.4 West Germany 73.0 5.8 France 39.5 3.1 Japan 26.5 2.1 Belgium 23.0 1.8 Sweden 18.5 1.5 Denmark 17.5 1.4 Holland 15.0 1.2 Italy 13.4 1.0 Mexico 10.0 0.8 Canada 5.0 0.4 Other countries 24.0 1.9 Source not ascertained 75.0 6.0 1,265 100.0 United States Total Source: Weidenbaum (1993) Is the FDA too Risk Averse? Two Types of Error in FDA Approval Decision Drug Is Beneficial Drug Is Harmful Type 1 Error: Allowing a harmful drug. FDA Allows the Drug Correct Decision Victims are identifiable and traceable, and might appear on Oprah. Error is self-correcting Type 2 Error: Disallowing a beneficial drug. FDA Does Not Allow the Drug Victims are not identifiable and scarcely even acknowledged in the abstract. Error is not self-correcting Correct Decision Regulating Drug Prices The economics of drug pricing High fixed costs; low marginal costs Problem Set #12 Price controls in the U.S. and abroad Danzon (1996): role of generics Impact of price controls on new drug development? R&D vs. Promotion Spending Source: R&D Spending: Pharmaceutical Research and Manufacturers of America, PhRMA Annual Membership Survey, 2004. Promotional Data: IMS Health, Integrated Promotional Services™ and CMR, 6/2004 Benefits of Pharmaceuticals . New Medicines Account for 40% of Increase in Life Expectancy Number of Years Added to Longevity 2.0 Increase in Longevity due to NCE launches Total Increase in Longevity 1.5 1.0 0.5 0.0 1988 1990 1992 1994 1996 1998 2000 Source: F.R. Lichtenberg, “The Impact of New Drug Launches on Longevity: Evidence from Longitudinal, Disease-Level Data from 52 Countries, 1982-2001,” NBER: June 2003. . New Drugs Reduce Visits to Hospital and ER: Asthma Management Program Improves Outcomes for Children with Asthma 90% 85% Percent of Patients 80% 70% 55% 60% 50% 35% 40% 30% 30% 20% 10% 0% Before Program After Program ER Visits Before Program After Program Hospitalizations Source: P.J. Munzenberger and R.Z. Vinuya, “Impact of an Asthma Program on the Quality of Life of Children in an Urban Setting,” Pharmacotherapy, 22 (2002). Cost of Drug Therapy vs Surgery Disease Cost of Surgery Cost of Drug Therapy Drug Therapy as Percent of Surgery Ulcers $28,900 $900 3.1% Heart Disease $43,370 $300 0.7% Gallstones $12,000 $1,000 8.3% Source: Weidenbaum (1993) Confounding Factors HC Expenditures = P * Q Lifestyle Age Legal issues Technology • Pricing • Intensity of use Lifestyle Effects AIDS STDs Teenage pregnancies Liberal perspective: Alcohol abuse Cigarette smoking Drug Use Obesity due to failure in economic system in providing sufficient income earning opportunities due to breakdown of traditional Conservative perspective: family values with government as a contributor AIDS Cases in the U.S. Year 1985 1990 1995 2000 2005 2007 Males, 13 years and ol der 7,484 36,180 56,650 30,387 26,525 26,355 Females, 13 years and ol der 519 4,544 12,978 10,763 9,548 9,579 Chil dren < 13 Years Ol d 128 725 745 117 54 28 Total 8,131 41,449 70,373 41,267 36,127 35,962 All Years 810,676 198,544 9,209 1,018,428 Source: Health, United States, 2009: With Chartbook on Trends in the Health of Americans, Tab le 48. Cases have stabilized at 36,000 annual cases AIDS by Exposure Category 1990 Number, by year of report 1995 2000 2007 Percent Di stribution Total To Date 100.0 40,740 69,774 40,230 35,962 Total To Date 1,018, 428 23,658 30,944 13,648 16,749 487,695 47.9 IV drug users 9,270 18,802 8,099 6,010 255,859 25.1 Homosexual/bisexual males and IV drug user 2,943 4,185 1,587 1,664 71,242 7.0 High-ri sk heterosexual contact 2,253 8,479 6,565 11,111 176,157 17.3 Hemophilia/Blood tranfusion 1,117 1,032 395 401 18,266 1.8 Source Total Case s Homosexual/bisexual males Source: Health, United States, 2002: With Chartbook on Trends in the Healt h of Americans , 2002, Table 55. And HIV Surveillance Report, 2007, Vol. 19. AIDS in America Extent of AIDS Worldwide: 36-40m living with HIV; 22m deaths United States: 1m cases; 400,000+ deaths Medical care issues Hellinger (1992): lifetime costs of $70,000 Cocktail Protease inhibitors: $7400/yr AZT: $3500/yr 3TC: $2800/yr $12,000 - $16,000 pppy $16,000 x 750,000 = $12 billion Drug Abuse Extent of Drug Use Cost to society Intervention strategies Use of selected substances in the past month, by age, 2007 Age Any Illicit Drug Marijuana Alcohol Cigarettes 12-13 yrs 3.3 0.9 3.5 1.8 14-15 yrs 8.9 5.7 14.7 8.4 16-17 yrs 16.0 13.1 29.0 18.9 18-25 yrs 19.7 16.4 61.2 36.2 26-34 yrs 10.9 7.9 62.6 33.4 4.6 3.0 52.2 22.0 51.1 24.2 35 + 12 and over 8.0 5.8 Source: Health United States, 2009: With Chartbook on Trends in the Health of Americans, 2009, Table 63. Use of selected substances among US high school seniors Year Alcohol Cigarettes Marijuana Cocaine Inhalants MMDA 1980 72.0 30.5 33.7 5.2 1.4 -- 1990 57.1 29.4 14.0 1.9 2.7 -- 1995 51.3 33.5 21.2 1.8 3.2 -- 2000 50.0 31.4 21.6 2.1 2.2 3.6 2003 47.5 24.4 21.2 2.1 1.5 1.3 2004 48.0 25.0 19.9 2.3 1.5 1.2 2005 47.0 23.2 19.8 2.3 2.0 1.0 2006 45.3 21.6 18.3 2.5 1.5 1.3 2007 44.4 21.6 18.8 2.0 1.2 1.6 Source: Health United States, 2009: With Chartbook on Trends in the Health of Americans, 2009, Table 64. Prevalence of Tobacco Use 25 Years and Older Percent smokers Year 1974 1979 1985 1990 1995 2000 2005 2006 2007 Male 42.9 37.3 32.8 28.2 26.4 24.7 22.7 22.9 21.4 Female 32.0 29.5 27.5 22.9 22.9 20.5 18.0 17.9 17.2 Source: Health United States, 2009: With Chartbook on Trends in the Health of Americans, 2009 Tab le 61. Economic Costs of Drug Abuse in the US, 2000 (millions of dollars) Cost Categories Estimated Cost Health Care Community-based Drug-abuse Treatment $5,594 Federally Provided Drug-Abuse Treatment $506 Support for Drug Abuse-Related Health Services $2,084 Medical Consequences of Drug Abuse $6,715 Total Health Care $14,899 Productivity Losses Premature Death $18,256 Drug Abuse-Related Illness $25,435 Institutionalization/Hospitalization $1,915 Productivity Loss of Victims of Crime $2,217 Incarceration $35,601 Crime Careers $27,066 Total Productivity Losses $110,491 Other Costs Cost of Goods and Services Lost to Crime Social Welfare Administration Total Other Costs Total Economics Costs Source: US National Drug Control Policy, 2001 $35,056 $218 $35,274 $160,664 Is Addiction Rational? When does a habit become an addiction? Becker and Murphy (1988) Past consumption increases current consumption People make forward-looking consumption plans Policy Implication: if cigarette taxes are credibly announced to double in one year, then current consumption will decrease Gruber and Koszegi (2001) Forward looking behavior is not consistent over time Policy should take into consideration not only externalities of behavior, but “internalities” Smokers die on average 6.1 years prematurely. At $100,000/year, cost per pack smoked is $30.45 Obesity BMI > 30 Obesity BMI > 30 30% of Americans Health Problems Diabetes Hypertension Cardiovascular disease Colon cancer Postmenopausal breast cancer Finkelstein, Fiebelkorn, and Wang (2003) Direct costs of obesity ~ $90 billion 9% of total medical expenditures Aging of the Population Elderly in the U.S. Percent of total civilian population Year 1950 1960 1970 1980 1990 1995 2000 2005 2010 2020 2030 2040 2050 Over 65 8.1 9.2 9.9 11.3 12.5 12.8 12.4 12.4 13.3 16.4 20.1 20.7 20.4 65-74 5.5 6.1 6.1 6.9 7.3 7.2 6.5 6.3 7.0 9.5 10.9 9.1 8.8 75-84 2.2 2.6 3.0 3.4 4.0 4.2 4.4 4.4 4.4 4.8 6.7 7.9 6.8 Over 85 0.4 0.5 0.7 1.0 1.2 1.4 1.5 1.7 2.0 2.1 2.5 3.7 4.8 Source: Economic Report of the President, 1994, Table B-32, p. 305 and Health, United States, 2007 Table 1. Personal Health Care Expenditures by Age and Type of Service (2004) Per capita dollars Age Group Personal Health Care Hospital Care Physicians’ Services Nursing Home Services Other Less than 19 $ 2,650 $ 1,000 $ 753 $ 18 $ 879 4,511 1,636 1,256 127 1,492 65 + over 14,797 5,403 3,024 2,526 3,844 65-74 10,778 4,191 2,716 809 3,062 75-84 16,389 6,178 3,463 2,623 4,125 85 + over 25,691 7,916 3,037 8,706 6,032 5,276 1,928 1,339 115.0 1,894 19-64 All ages Source: http://www.cms.hhs.gov/NationalHealthExpendData/downloads/2004-age-tables.pdf Utilization of Medical Care Resources, 2005 Age Group Less than 18 18-44 45-64 65-74 Over 75 All persons Out-Patient Visits per 100 Population 33 26 32 41 38 33 Days of Hospital Care per 100 Population 19.2 33.1 59.2 139.9 259.4 55.4 Source: Health, United States, 2003 and 2007. * 2001 data. Inpatient Procedures per 100 Population (Males)* 4.0 5.0 16.2 37.6 56.5 12.5 Inpatient Procedures per 100 Population (Females)* 3.7 19.0 15.2 33.0 45.6 16.7 Physician Office Visits Per 100 Population 253 224 391 647 768 329 Americans' Current Health Care Expenditures Are Concentrated in the Final Part of the Life Span Source: Joanne Lynn, David M. Adamson, Rand Health White Paper WP137 (2003). Available at http://www.medicaring.org/whitepaper/ Legal System and Malpractice Medical Malpractice Tort Costs 0.30% $30 0.25% $25 Billions . 0.20% $20 Share of GDP 0.15% $15 Tort Costs 0.10% $10 0.05% $5 $0 1975 0.00% 1980 1985 1990 1995 Source: 2009 Update on U.S. Tort Costs, Towers Perrin, 2009. 2000 2005 Share of GDP $35 . (Billions of 2008 $) Tort Law in the United States Four elements of a tort case Presence of a physician-patient relationship An adverse outcome Negligence by the provider Direct causality between the negligence and adverse outcome Purpose of tort law Compensation Deterrence Retribution Claims Frequency by Specialty Date All Physicians General/ Family Practice Internal Medicine Surgery Obstetrics/ Gynecology 1985 10.2 5.7 6.2 16.8 25.8 1986 9.2 7.6 5.5 15.8 13.0 1987 6.7 5.7 4.5 12.7 8.0 1988 6.4 6.2 4.3 10.2 15.1 1989 7.4 6.6 5.9 11.2 13.5 1990 7.7 5.9 6.2 11.5 11.9 1991 8.2 5.7 5.5 14.0 11.6 1992 9.1 6.9 7.3 15.5 15.6 1993 9.8 7.1 7.9 18.9 22.5 1994 9.5 6.7 5.7 16.9 19.2 1995 9.0 6.2 5.7 14.9 20.9 1996 9.0 6.7 5.3 14.9 13.1 Source: Martin L. Gonzalez, ed., Socioeconomic Characteristics of Medical Practice, Chicago: American Medical Association, various years. Malpractice Premiums by Specialty as a percentage of professional expenses All Physicians General/ Family Practice Internal Medicine Surgery Obstetrics/ Gynecology 10.2 10.8 12.1 11.3 10.4 9.7 8.7 7.6 7.9 8.2 7.4 6.5 7.0 6.1 7.3 7.7 7.0 5.8 5.5 5.2 4.9 5.4 5.0 4.0 6.4 6.4 7.1 6.6 5.9 6.6 5.0 4.9 4.9 4.6 4.7 4.6 12.2 14.3 14.9 14.1 12.7 11.3 10.4 8.6 9.2 8.9 8.8 7.1 17.8 19.6 20.4 18.6 18.7 16.1 14.8 14.3 14.2 19.0 14.4 13.2 Year 1985 1986 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 Source: Martin L. Gonzalez, ed., Socioeconomic Characteristics of Medical Practice, Chicago: American Medical Association, various years. International Comparison of Malpractice Awards (2001) Claims per 100 physicians Claims per 100,000 population Average claim awarded (PPP US $) United States Australia Canada United Kingdom 7.67 4.72 1.90 6.00 18 12 4 12 $265,103 $97,014 $249,750 $411,171 Source: Anderson, Hussey, Frogner, and Walters (2005) Causes of Increased Litigation Increased supply of lawyers Increased litigiousness in US Increased medical cost and physicians’ salaries Breakdown of physician-patient relationship Pro-plaintiff trend in common law doctrine Size of damage awards Increased technology in medicine Silicone Implant Litigation Silicone implants first introduced in 1962 by Dow Corning FDA relabeled implants as class III medical device in 1988 FDA moratorium in 1992 National class action lawsuit with thousands of plaintiffs $4.25 billion settlement with 40% going to attorneys Dow Corning bankruptcy FDA removed moratorium in 2006 Medical Technology Technological change Cost-increasing technological change Cost-decreasing technological change MRI Machines, 2007 MRI (per million population) 0 10 20 30 Japan 40.1 United States 25.9 Iceland 19.3 Italy 18.6 16.0 Korea Finland 15.3 Switzerland 14.4 Greece 13.2 OECD 11.0 Luxembourg 10.5 Denmark 10.2 Spain 9.3 New Zealand 8.8 United Kingdom 8.2 Germany 8.2 Canada 6.7 France 5.7 Turkey 5.6 Australia 5.1 4.4 Czech Republic Poland Mexico 40 2.7 1.5 CT Scanners, 2007 CT Scanners (per million population) 0 10 20 30 40 50 60 80 90 100 92.6 Japan (2002) 56.0 Australia 37.1 Korea 34.3 United States Iceland 32.1 30.3 Italy 27.3 Luxembourg 25.8 Greece 22.8 OECD Sw itzerland 18.7 17.4 Denmark Finland 16.4 Germany 16.3 Spain 14.6 Ireland 14.3 Canada 12.7 New Zealand 12.3 France 10.3 Poland 9.7 Turkey 8.1 United Kingdom 7.6 Mexico 70 4.0 te d Cz ec h Un i te d Au st ra lia Fr an ce Re pu bl ic y ng do m Hu ng ar Ki Ca na da Sp ai n O EC D Be lg iu m bo ur g nd at es Ic el a St Lu xe m Un i MRI Exams per 1000 population 2007 100.0 90.0 80.0 70.0 60.0 50.0 40.0 30.0 20.0 10.0 0.0 te d Un i te d Cz ec h at es nd lia Fr an ce y ng do m Hu ng ar Ki Sp ai n Re pu bl ic Au st ra Ca na da O EC D Ic el a Be lg iu m bo ur g St Lu xe m Un i CT Exams per 1000 population 250.0 200.0 150.0 100.0 50.0 0.0 High-cost Medicine Heart disease Angioplasty: 1 million @ $10,000 each CABGS: 500,000 @ $50,000+ each Heart transplantation: 2,212 @ $787,000 each Infertility treatment IUI (intrauterine insemination): $1000-$2000 per cycle IVF (in vitro fertilization): $10,000-$12,000 per cycle GIFT (gamete intrafallopian transfer): $15,000-$20,000 per cycle Organ Transplantation History National Organ Transplant Act (1984) What Can be Transplanted? Organs Cornea (1905) Kidney (1954) Pancreas (1966) Heart (1967) Liver (1967) Lungs (1987) Intestines (1987) Penis (2006) Tissue Skin Bone marrow Bone Blood vessels Hand (1998) Face (2005) National Organ Transplant Act (1984) Banned sale of organs in US 5 year prison $50,000 fine Created Organ Procurement and Transplantation Network (OPTN) Regional system of organ distribution Hospitals required to notify OPTN of possible donors Hospitals required to notify potential donors of their options United Network for Organ Sharing Operates OPTN Allocation Criteria Medical History Blood type Location Time on Waiting List Number of U.S. Transplants Year Kidney Pancreas Liver Heart Lung 69 109 439 542 436 379 6,530 Kidney/ Pancreas 458 919 915 903 837 854 16,710 1990 1995 2000 2005 2008 2009 Total to date 9,417 11,084 13,619 16,483 16,520 16,829 284,156 Candidates on Waiting List 2,690 3,934 4,997 6,444 6,319 6,320 100,784 2,107 2,363 2,199 2,125 2,163 2,212 47,487 89,537 1,496 2,284 16,574 $259,000 $275,200 $439,000 1-year (%) 95.6 95 3-year 90.3 90.2 2008 Average Billed Price Intestine 203 872 959 1,406 1,478 1,661 19,775 Heart/ Lung 52 69 48 35 27 29 1,021 3,166 1,881 72 241 $523,400 $787,000 $450,400 $1,123,000 $1,121,800 94.4 86.7 88.0 83.2 55.6 82.2 90.4 78.3 79.3 62.2 44.3 57.0 5 46 82 178 185 178 1,884 Patient survival rate Market for Organs Supply and demand for organs Property rights U.S. policy—required request Rest of Europe—presumed consent Deceased and Living Kidney Donors 1990- 2009 8000 7000 6000 5000 4000 Deceased Living 3000 2000 1000 0 1990 1995 2000 2005 2010 Market for Body Organs Gov’t prohibits trade in organs At P = 0: Qd > Qs shortage results S1 Price P1 Non-Price Rationing Black Market Bribes Discrimination Wait / Search D1 16 90 Kidneys (1000s) Shortage Wait List Death Rates 1995-2009 40 35 30 P e 25 r c e 20 n t a 15 g e 10 5 0 1994 1996 1998 2000 Kidney 2002 Liver 2004 Heart Lung 2006 2008 2010 Organ Rationing Schemes Allocation Methods Waiting time Priority to sickest first Benefits Costs Equitable Inappropriate matching; organ wastage; no consideration of urgency Equitable Higher retransplantation and death rates; less benefit overall Priority to sickest last Higher overall survival; less retransplantation Sickest patients die Best Biological Match Higher overall survival; less retransplantation Fewer transplants for certain groups, including highly sensitized patients and some minorities Source: Charles T. Carlstrom and Christy D. Rollow, The Cato Journal (Vol. 17, #2) Fall 1997 Market for Body Organs Gov’t prohibits trade in organs S2 At P = 0: Qd > Qs shortage results P1 Non-Price Rationing P2 Black Market Bribes Discrimination Wait / Search Free Market: P2, Q2 S1 Price D1 16 Q2 Shortage 90 Kidneys (1000s) Iranian Model Legalized the sale of kidneys Officially approved patients’ organization oversees all transactions Donors get $2000 - $4000 Waiting list has been eliminated Source: The Economist, November 16, 2006, available at http://www.economist.com/world/international/displaystory.cfm?story_id=8173393 Cost of Transplant Surgery, 2008 Organ Number Transplanted Kidney Heart Liver Heart/Lung Pancreas Lung 16,520 2,163 6,319 27 436 1,478 Total 26,943 Estimated Cost1 (millions) $ Estimated Average Cost per transplant Number on Waiting List 4,278.7 1,703.8 3,307.4 30.3 120.1 665.7 $ 259,000 787,700 523,400 1,123,800 275,500 450,400 89,537 3,166 16,574 72 1,496 1,881 $10,106.0 - 112,726 1. Number transplanted times average cost of the transplant procedure. 2. Number on waiting list times average cost of the transplant procedure. Estimated Cost if Donor Organs were Available2 $ 23,190 2,494 8,675 81 412 847 $35,699 Total Estimated Cost (millions) $ 27,469 4,197 11,982 111 532 1,513 $45,805