AP Lang and Comp 3rd h. Miss Clark Persuasive Speech Outline Persuasive Speech Outline I. Introduction A. Lizards are able to re grow a tail. (attention grabber) B. Wouldn’t it be incredible if this ability could also be extended to humans? (Ethical appeal, what people value) What looks like science-fiction is closer to reality than you think. It is the realm of regenerative medicine, brought to us by scientists who study stem cells. C. I believe stem cell research should be further developed. (thesis statement) II. Narration A. What are stem cells? 1. They are unspecialized cells. 2. They can become another type of cell with a specific function like a red blood cell, brain cell, or skin cell. 3. They are capable of dividing and renewing themselves for a long time. For these reasons stem cells have the potential to treat many diseases such as diabetes, heart disease and blood disorders if they are injected in the body. Another function of stem cells is to grow tissue outside the body, in a lab, and even create synthetic blood that can be used in medicine. B. Where can we find them? 1. The easiest place to find them and where scientists can find the most are in embryos. 2. They are also in the umbilical cord of newborns. 3. Adults also have stem cells in smaller amounts, in their bone marrow, skin, nervous system etc. III. Confirmation I am in favor of stem cell research because… A. It can cure diseases 1. Example of successful treatment of blind patients with retina tissue grown from embryonic stem cells (Pollack). (evidence) B. It advances knowledge. 1. The discovery of reverting specialized adult cells back to pluripotent stem cells that will further develop into different specialized cells. Example of taking human skin cells and reprogramming them to revert back into stem cells which in turn are used to create liver cells (Artificial Liver). (Evidence) 2. It also advances knowledge of how healthy cells replace damaged cells in adults. Example of stem cell infusions which helped heart attack patients to re grow healthy heart tissue (Brown). (Evidence) IV. Refutation A. The fear that injecting stem cells might create tumors. 1. No tumors have been reported after therapies with stem cell. (Pollack) 2. Stem cells can actually be used to destroy tumors. Several hundred mice have been cured of brain cancer called neuroblastoma by injecting adult mice stem cells (Kaplan). (Evidence) B. People are afraid because it is so new. 1. Yes, it is normal to be fearful of the unknown (concession) but for the Chinese it is not so new, they have performed therapies on many patients because of their advanced research and also hold international conferences on stem cells. C. It is immoral to use embryos and to destroy them. (O’Brian) 1. Embryos used for stem cell research come from fertility clinics. The fertilization of ovula and sperm is done in vitro (in test tubes). A couple donates extra embryos to research if they wish. 2. If not donated, those embryos are thrown away anyways. 3. When scientists use embryos for research it is not destroying human life, but rather providing stem cells that could save millions of lives in the future, and that is morally sound. 4. We can use adult stem cells instead of embryonic for therapies for example. A synthetic windpipe made in a laboratory is seeded with stem cells taken from the patient’s bone marrow and successfully implanted to replace the cancerous trachea (Fountain). (Evidence) D. This new technology can be abused to gain money or pride. 1. Yes, but this is true of any new technology. Internet for instance can be used for good or bad. Technology does not have a moral compass. It is only as “good” or “evil” as the person or society using it (Lanza).(concession) 2. “Human imperfections should not lead society to dismiss innovation”(Lanza). V. Conclusion By continuing stem cell research we can: A. Participate in the incredible advancement in the history of science (regenerative medicine). B. Ease suffering, understand and treat disease. C. The ultimate goal is to take discoveries from the lab to the hospital. Works Cited “Artificial Liver Cells Win their Creator Prize for their Potential to Reduce Animal Experiments”. University of Cambridge, UK. Web. 28 Feb. 2012. 6 March 2012. http://news.admin.cam.ac.uk/news/2012/02/28/artificial-liver-cells-win-their-creator-prize-for-theirpotential-to-reduce-animal-experiments Brown, Eryn. “ Study: Cardiac Stem Cells can Reverse Heart Attack Damage.” Los Angeles Times. Web. 13 Feb. 2012. 6 March 2012. http://www.latimes.com/health/boostershots/la-heb-stem-cells-heartattack-20120213,0,580619.story Fountain, Henry. “Synthetic Windpipe Is Used to Replace Cancerous One”. New York Times. Web. 12 Jan. 2012. 6 March 2012. http://www.nytimes.com/2012/01/13/health/research/surgeons-transplantsynthetic-trachea-in-baltimoreman.html?scp=1&sq=synthetic%20windpipe%20is%20used%20to%20replace%20cancerous%20one&st= Search Kaplan, Karen. “Grant Money Could Speed Stem Cell Cure.” Los Angeles Times. Web. 10 Jan. 2010. 6 March 2012. http://www.latimes.com/news/nationworld/nation/la-sci-stem-cells102010jan10,0,2536499.story Lanza, Tyler. “The Stem Cell Research Controversy”. Stem Cell History. Web. 1 Feb. 2011. 6 March 2012. http://stemcellhistory.com/the-stem-cell-research-controversy/ O’Brien, Nancy F. “ Embryonic Stem Cell Research, Immoral, Unnecessary, Bishops Say”. American Catholics. Web. Copyright 2012. 6 March 2012. http://www.americancatholic.org/news/stemcell Pollack, Andrew. “Stem Cell Treatment for Eye Diseases Shows Promise.” New York Times. Web. 23 Jan. 2012. 6 March 2012. http://www.nytimes.com/2012/01/24/business/stem- cell-study-may-showadvance.html?_r=1&scp=1&sq=stem%20cell%20treatment%20for%20eye%20diseases%20s hows%20promise%20&st=cse