Virology Exam 2010 Selected Questions and Answers 1. A 30 yr. old man has a blood test that is HBsAg negative, Anti-HBc negative, and anti-HBs positive. He most likely a. is immune to HBV b. is suffering an acute infection of HBV c. is suffering a chronic infection HCV d. is infected with HDV e. has contracted an STD from the Immunology department of his university 9. Which one of the following statements about genital herpes is least accurate? a. Acyclovir reduces the frequency of recurrent disease episodes by eradicating latently infected cells. b. Genital herpes can be transmitted in the absence of apparent lesions. c. Herpes simplex virus can be isolated from genital lesions by tissue culture. d. Primary disease episodes are generally more severe than recurrent episodes. e. Genital herpes can be caused by both HSV-1 and HSV-2. 15. Genotype resistance involves cell culturing the virus with anti viral drugs. a. True b. False 27. An adult exposed to a child with chicken pox will experience herpes zoster a. True b. False 35. Which of the following sentences describing the structure of viruses is correct (the most comprehensive correct answer) a. A helical viral capsid can be assembled in the absence of the viral nucleic acid. b. An icosahedral viral capsid can be assembled in the absence of the viral nucleic acid. c. Both helical and icosahedral capsids can be assembled in the absence of a viral nucleic acid. d. All virus families have either a helical or an icosahedral capsid. 36. Cells from a transplanted kidney from a CMV positive patient (in the latent stage) can undergo reactivation in the recipient. a. True b. False 41. Which of the following viruses can be sexually transmitted? a. Hepes b. HIV c. Human papiloma virus d. Hep B e. all of the above viruses can be sexually transmitted 53. Which one of the following statements about genital herpes is least accurate? a. Acyclovir reduces the frequency of recurrent disease episodes by eradicating latently infected cells. b. Genital herpes can be transmitted in the absence of apparent lesions. c. Herpes simplex virus can be isolated from genital lesions by tissue culture. d. Primary disease episodes are generally more severe than recurrent episodes. e. Genital herpes can be caused by both HSV-1 and HSV-2.