http://www.youtube.com/watch?v=zTWZtElv MAU&feature=related (revolting facts) vector borne direct contact antibiotic vaccines epidemic carrier indirect contact fomite antiviral outbreak pandemic borne GUIDING QUESTIONS 1. What is the difference between indirect contact, direct contact, and vector borne? Describe examples of each. 2. What is the difference between an outbreak, epidemic, and pandemic? Describe an example of each. 3. What are the main differences between antibiotics and vaccines? 4. What are the similarities between antibiotics and vaccines? 5. What is the relationship between cold weather and becoming sick? TERMS Pathogen - a micorbe that causes disease Transmission of a disease – the path a pathogen takes to get from host to host Host – the infected organism Carrier – an organism that harbors a pathogen and can transmit the pathogen to others but shows no symptoms • • • • Direct contact Indirect contact Food/air-borne Vector borne 4 MAIN TRANSMISSION PATHS FOR PATHOGENS • • • • Direct contact Indirect contact Food/air-borne Vector borne For each you need to know: 1.The definition 2.How the transmission occurs 3.Examples https://www.youtube.com/watch?v =RWiOhlqEDz4 ASAP science DISEASE TRANSMISSION PATHWAYS: DIRECT CONTACT Direct contact - transmission requires physical contact with an infected person Direct contact through: kissing, sexual contact, oral secretions (saliva), blood, or contact with body lesions(sores or open wounds). Examples of pathogens spread though direct contact: Cold, flu, HIV, Staphylococcus bacteria, Hepatitis A • • • • Direct contact Indirect contact Food/air-borne Vector borne DISEASE TRANSMISSION PATHWAYS: INDIRECT CONTACT Indirect contact – a person is infected from contact with a contaminated surface (called a fomite). Some microbes can survive on surfaces for a long period of time Indirect contact includes: touching contaminated surfaces then putting contaminated hands or fingers in mouth, eyes, nose, etc. Examples: flu, Hepatitis B, HIV (via contaminated needles) Fomites Watch the video: http://www.youtube.com/watch?v=yToii3-p-NI • • • • Direct contact Indirect contact Food/air-borne Vector borne DISEASE TRANSMISSION PATHWAYS: FOOD BORNE PATHOGENS Food Borne- transmission through eating or drinking water or food that is contaminated with feces (poop) or eating contaminated meat that is undercooked meat Process – Pathogens enter the body through ingestion and inside the digestive system (usually within the intestines) these microorganisms multiply and are then shed from the body in feces. • • • • Direct contact Indirect contact Food/air-borne Vector borne DISEASE TRANSMISSION PATHWAYS: AIR BORNE Air Borne- residue from evaporated droplets or dust particles containing microorganisms remain suspended in air for long periods of time, capable of surviving for long periods of time outside the body and must be resistant to drying. transmission occurs when these droplets enter the upper and lower respiratory tracts of a person Examples: Tuberculosis , Chickenpox, Measles, Valley Fever • • • • Direct contact Indirect contact Food/air-borne Vector borne DISEASE TRANSMISSION PATHWAYS: VECTOR BORNE Vector Borne - vectors are animals that are capable of transmitting diseases, transmission requires physical contact with a vector. Or the vector‘s feces Vector Borne includes: Examples of vectors are flies, mites, fleas, ticks, rats, dogs, and mosquitoes (the most common vector ). Mosquitoes transfer disease through the saliva which comes in contact with their hosts when they are withdrawing blood. Examples: malaria, rabies, Lyme disease, West Nile Virus, Giardia, bubonic plague • • • • Direct contact Indirect contact Food/air-borne Vector borne REDUCING DISEASE TRANSMISSION Vaccines Antibiotics Antivirals Antifungals http://www.who.int/csr/don/en/ http://www.cdc.gov/outbreaks/ http://www.youtube.com/watch?v=d5qovHD_kjQ VACCINES Produced using bacteria or Examples for virual viruses that are…….. pathogens Examples for bacterial pathogens weakened (attenuated): can measles, mumps, only reproduce <20 times. chickenpox Typhoid Inactivated: cannot reproduce polio, hepatitis A, influenza, rabies plague, cholera Broken up into proteins taken from the surface of the virus OR toxins produced by the bacteria. hepatitis B, HPV Purpose: to stimulate the production of antibodies and provide immunity to disease ANTIBIOTICS – CHEMICAL MADE TO KILL BACTERIA 90% of antibiotics are made from bacteria or fungi Produced by a process of fermentation - the source microorganism is grown in large containers (100,000– 150,000 liters or more) containing a liquid growth medium. Antibiotics destroy the bacteria or prevent bacteria from reproducing ANTIBIOTIC RESISTANCE “Each year in the United States, at least 2 million people become infected with bacteria that are resistant to antibiotics and at least 23,000 people die each year as a direct result of these infections.” (Threat 2013) The diversity of helpful bacteria in your colon can be negatively affected for up to one year after taking antibiotics. (Fang 2015) http://www.youtube.com/watch?v=zjR6L38yReE ANTIVIRALS Made primarily from inactivated viruses Antivirals do not destroy the viruses - they inhibit the reproduction by blocking the ‘keys’ on the virus ANTIFUNGAL Destroys the cell wall of the fungal cells Prevents the fungus from growing and reproducing https://www.youtube.com/watch?v=RWiOhlq EDz4 (cold facts) • Ro is the basic reproduction number for infectious diseases • Ro is the number of people one infected person infects • For example: an Ro value of 3 means that each infected person will infect 3 other people BASIC REPRODUCTION NUMBER FOR INFECTIOUS DISEASES, RO Fang, Janet. "Just One Antibiotic Treatment Can Alter Your Gut Microbiome For A Year." Health and Medicine. IFLScience, 13 Nov. 2015. Web. 15 Nov. 2015. <http://www.iflscience.com/health-and-medicine/just-one-antibiotic-treatmentcan-alter-your-gut-microbiome-months>.