Introduction to the cell biology course (3MB002/5MO021) The course is divided into three parts: 1. The theory part, 8 ECTS-credits, comprises comprehensive theoretical knowledge of the most central parts of modern Molecular Cell Biology. The main areas are described under the heading "expected study results". 2. Practical Professional Training (PPT), 2 ECTS-credits, comprises oral presentation of mini-case and study questions (mandatory exercises!). 3. Lab course, 5 ECTS-credits, which includes 1 ECTS-credit lab report writing is an application of the theoretical part. The experimental exercises include work in model systems and methodology for cell biological studies. A consistent theme during part 3 of the course is that participants will receive training in independently planning experiments and analyses. Moreover, there will be an emphasis on how to compile an individual laboratory report to be presented in the same format as a scientific article. The students will be trained in good laboratory practice with respect to keeping dated notes in a laboratory journal i) Each student will be provided with a note book in which laboratory protocols and results should be clearly documented ii) The course assistants will provide continuous feed-back on how experiments are documented iii) At the end of the course, these note books will be collected by the course assistants for assessment iv) A clear and dated laboratory record is required for the student to pass the laboratory course 1 Cell biology 15hp - course outline XX/X YY/Y Lecture course ZZ/Z Lab course Exam The theoretical part of this course covers 5 weeks and ends with a written exam. It involves four mandatory study questions/mini-case case sessions (2 ECTS-credits), which covers all central topics of this cell biology course. The practical part of this course covers 4.5 weeks and involves writing a lab report in a format corresponding to a scientific publication. Students need to both pass the written exam and to have their practical work and lab reports approved 2 Pedagogic principle – section 1 to 4 Literature studies etc Introductory lectures on section 2 De-briefing of study questions/mini-cases section 1 Mandatory, 2 ECTS-credits Study questions/mini-cases Literature studies Introductory lectures on section 1 3 Alberts et al. 5th edition The study questions/mini-cases The cases •“Mini-cases” that requires knowledge from the introductory lectures, “Albert et al.” and previous course segments • Individual studies or in groups • Optional ”open office” according to schedule • Serve as a detailed study-guide Discussion session • You will discuss each mini-case with a randomly selected peer (5-10 min) • Each mini-case is thereafter presented by a randomly selected pair of peers ”Utbildning på grundnivå skall utveckla studenternas: - förmåga att muntligt och skriftligt redogöra för och diskutera information, problem och lösningar i dialog med olika grupper” Högskolelagen (SFS nr: 1992:1434 uppdaterad t.o.m SFS 2006:173) 4 Topics of the course a complete overview of cell biology Lecture 1: How to study cells Lecture 2: Membrane biology and cellular organelles Lecture 3: Cell organelles and intracellular trafficking End section 1/week 1: study questions/mini-cases Lecture 4: Cellular communication I Lecture 5: Cellular communication II End section 2/week 2 : study questions/mini-cases Lecture 6: Cell cycle I Lecture 7: Cell cycle II and cell death End section 3/week 3 : study questions/mini-cases Lecture 8: Cytoskeleton I Lecture 9: Cytoskeleton II Lecture 10: Cell adhesion and ECM End section 4/week 4 : study questions/mini-cases Lecture 11: Cytoskeleton, cell cycle & disease Lecture 12: Summary lecture with a tumor biology perspective Week 5: end of the theoretical part of the course exam 5 An undergraduate's view of cell biology SecA Paradigm System Causal relationship AUG A more productive view of cell biology Facts Fakta LRP ER Frizzled tRNA OXA MHC 6