Module 2 Health and Medical Effects 1 Health and Medical Effects Terminal Objective: DESCRIBE the indicators, signs, and symptoms of exposure to radiation. 2 Health and Medical Effects Enabling Objectives: 1. LIST the major sources of natural background and man-made radiation. 2. STATE the average annual dose to the general population from natural background and man-made sources of radiation. 3. DESCRIBE the purposes of radiation dose limits and the guidance for emergency doses. 3 Health and Medical Effects Enabling Objectives (continued): 4. DESCRIBE acute radiation dose and chronic radiation dose and the possible effects of each. 5. STATE the routes of entry by which radioactive material can enter the body. 4 Sources of Natural Background Radiation • Cosmic Radiation • Sources in the Human Body • Sources in the Earth’s Crust • Radon 5 Cosmic Radiation • Cosmic radiation comes from the sun and outer space. • At sea level, the average annual cosmic radiation dose is about 26 mrem per year. • The higher the elevation, the higher the dose of cosmic radiation. • The exposure increases about 1 mrem per year for every 100 feet up in altitude. 6 Terrestrial Radiation Sources in the Earth’s Crust • Ground, rocks, soil, and sand • Sources – natural radioactive elements of radium, uranium, thorium, and potassium 7 Terrestrial Radiation average in continental U.S.: 28 mrem per year Terrestrial Radiation average in continental US: 28 mrem per year 75 55 40 15 mrem per year 8 Internal Sources of Natural Background Radiation • Sources in the human body • Food and water in trace amounts • Naturally occurring radioactive materials deposited in our bodies • Combined exposure from internal sources – radioactive dose of about 40 mrem per year 9 Radon • (Gas) formed from the radioactive decay of uranium in the soil • Can collect in basements • Emits alpha radiation 10 Man-Made Sources of Radiation • Tobacco products • Medical radiation • Building materials • Domestic water supply 11 Sources of Radiation NATURAL BACKGROUND Cosmic Radiation Terrestrial (Earth’s crust) Internal Sources (body) Radon mrem/year 26 28 40 200 MAN-MADE SOURCES mrem/year Smoking (Tobacco Products) 1300 Medical X-rays 40 Medical Diagnosis and Therapy 14 Building Materials 7 Domestic Water Supply 5 12 Sources of Radiation Total of natural background and man-made sources for the average American (non-smoker): 360 mrem per year (about 1 mrem per day) Average due to smoking cigarettes (1 pack a day): 1300 mrem per year (about 3 mrem per pack) Round-trip airline flight across the U.S.: about 5 mrem 13 Biological Effects QuickTime™ and a Cinepak decompressor are needed to see this picture. 15 Effects of Radiation on Cells • • • • • Atoms Molecules Cells Tissues and Organs Body 16 Effects of Radiation on Cells (cont.) Some cells are more sensitive: • Blood • Cells that form sperm • Intestinal tract • Hair follicles 17 Effects on Cells Exposed to Ionizing Radiation • No damage • Repair and operate normally • Damaged and operate abnormally • Cells die 18 Biological Pathways Inhalation Absorption Ingestion Puncture or Injection 19 Acute vs. Chronic Radiation Doses Acute • Large dose • Short time Chronic • Small doses • Long time 20 Acute Radiation Dose Exposure to high doses of radiation over a short period of time (minutes, hours, days) 21 Biological Effects of Radiation Exposure • Damage in exposed individual • No proven cases of genetic damage to humans passed on to future children • Survivors of Hiroshima and Nagasaki: genetic mutations in their children no higher than the general population 22 Factors Affecting Cell Damage • • • • • • • Total dose Dose rate Type of radiation Area of the body Cell sensitivity Individual sensitivity General state of health 23 Acute Radiation Effects Dose Less than 50,000 mrem • No symptoms Between 50,000 and 100,000 mrem • Temporary lowering of white cell count Between 100,000 and 200,000 mrem • Hours Later: Nausea, vomiting, diarrhea • No permanent disability 24 Acute Radiation Effects Dose (continued) Between 200,000 and 450,000 mrem • Vomiting, diarrhea, hair loss • 200,000 mrem lethal for 5% people in 60 days 450,000 mrem • Lethal Dose 50% in 60 days LD50/60 600,000 mrem • Death for most people 25 Radiation Burns Bronze-coloring, “tanning” of the skin Cloth Red-coloring, Swelling, Blistering Chernobyl Firefighter Victim from the country of Georgia 26 Radiation Burns – Gamma and Beta Radiation 27 Beta Burns from Contamination 28 Beta Burns on Foot 29 Beta Burns from Radioactive Fallout Healing Skin, 30 Days after Burn 30 Hair Loss 32 Casualties from a Nuclear Detonation 33 Effects of Nuclear Detonation • Thermal (flash) injuries from thermal pulse • Shock wave injuries, collapsed buildings • Radiation burns and sickness • Injuries from fires • External/internal contamination • Long-term effects 34 Thermal Pulse Injury from Nuclear Blast Flash Burns 36 Acute Exposure and Fatal Cancer Dose (mrem) Percent 1,000 0.08 5,000 0.4 10,000 0.8 25,000 2.0 50,000 4.0 38 Fatal Cancer Risk Estimates (Example) • 10,000 mrem dose – extra 0.8% • 1,000 survivors receive 10,000 mrem – estimated 8 extra cancer deaths • 200 cancer deaths from other causes • 208 total cancer deaths 39 Chronic Radiation Dose Risks • A small amount of ionizing radiation received over a long period of time (months, years) • Small increase in cancer risk 40 Estimated Loss of Life Expectancy from Health Risks Estimated Days Lost • Smoking one pack a day • Being 25% overweight 777 • Agricultural accidents 320 • Construction accidents 227 • Automobile accidents 207 • Chronic Radiation 2250 (1000 mrem per year from 18 to 65) 51 • All industry 50 • Chronic Radiation (100 mrem per year for 70 years) • Medical radiation 10 6 43 EPA Guidelines for Emergency Procedures Dose Limit: Maximum radiation dose that a responder is allowed to receive. Purpose of Dose Limit: Allow responders to perform emergency actions, yet keep risk as low as possible 44 EPA Guidelines for Emergency Procedures* (expected only once in a lifetime) Dose limit Emergency Activity Performed Condition All activities during 5,000 mrem All activities 10,000 mrem Protecting major property Where lower dose not practicable 25,000 mrem Lifesaving or protection of large populations Where lower dose not practicable Lifesaving or protection of large populations Only on a volunteer basis to persons fully aware of the risks involved. More than 25,000 mrem emergency * Minors and pregnant females have much lower limits 45 Health and Medical Effects 1. If there are low-level radiation readings, what are the possible sources of radiation? 2. How much radiation do you receive daily? 3. If there is radiation from the explosion, could it get onto or into your body? 4. What happens if radiation gets into the body? 46 47