Assessment

advertisement

Assessment

• Life history, critical incidents, current environment, congruence with symptoms

• Standardised measures

– PSYRATS

– BAVQ, IVI, BAPQ

– Mood, Safety behaviour interview, TCQ etc.

– PTCI, DES, CTQ, THQ

• SMART goals, belief ratings etc.

Formulation

4 levels:

• basic / horizontal

• maintenance

• internal generation

• historical / developmental / vertical

EVENT

Basic Formulation

THOUGHT FEELING BEHAVIOUR hear voice it’s the devil scared pray & visit church see ceefax I’m the devil scared p666 burn self

Maintenance Formulation

Triggers (cannabis, paranoid thoughts, arousal, religious )

Hear Voices scared, increased arousal no sleep pray, hide in church, attend to relevant stimuli

It is the devil trying to possess make me harm people

Historical Formulation

Early Experiences mental and sexual abuse from religious mother physical abuse from father to both told to harm father; told she was evil catholicism

Beliefs Formed

I am evil and the devil is in me

I might harm other people

Must think good thoughts

Thinking something evil is as bad as doing it

Critical Incident

Raped

Hear voices saying bad things

Intrusions / event

Social situations / reminders

Flashbacks / dissociation

Critical voices

Making sense of things

They are talking about me / want to hurt me

I’m mad / not normal

It’s a Bully from beyond the grave

Cog. & Beh. responses

Safety behaviours

Dissociation

Thought supression

Avoid situations

Run away

Look out for danger

Don’t express self

Beliefs / strategies / rules

I am vulnerable / useless

I am mad / not normal

People will hurt you & can’t be trusted

‘Paranoia’ keeps me safe

Bullying was my fault

If I keep busy or spaced out then I won’t have time to think / feel bad

Experience

Bullying

Physical Abuse

Emotional abuse

Mood & physiology

Anxious

Hyperarousal

Paranoid

Depressed

Sleep problems

Experiences that worry me

Hear whispering and laughing

See bodies

See people staring

What I make of it

They might be ghosts

I must be going mad

They might harm me

What I do

Try to stay in control of thoughts

Hide from ghosts

Look out for things happening to me

What I make of the self / world

I should be in total control

I am bad

Need to be alert for danger

Other people cannot be trusted

Early experiences

Baby brother died, mum blamed me

Sexually abused aged 14

Dad horrible to me

How I feel scared agitated angry sad

Formulation Exercise

• Role play assessment of patient and formulation

Video

• Developing case formulation

Exercise

• Suggest intervention strategies based on formulation

Normalising psychotic experiences

• Trauma (assault, bullying, kidnap, combat)

• Drug abuse

• Isolation / Sensory deprivation

• Bereavement

• Sleep deprivation

Some well known voice

• Philosophers and thinkers:

Socrates

Plato

Aristotle

Descartes

Mahatma Gandhi

hearers:

Spiritual and religious figures:

Moses

Jesus

Mohammed

Joan d'Arc

George Fox (Founder of the Quakers)

Leaders and rulers

Alexander the Great

Caesar

Oliver Cromwell

Napoleon

Churchill

• Authors, musicians and creative artists:

Jonathan Swift

Beethoven

Mozart

Byron

Edgar Allen Poe

Charles Dickens

Philip K Dick

Anthony Hopkins

Zoe Wanamaker

Paul McCartney

Brian Wilson

Scientists,Discoverers & Explorers

Christopher Columbus

Galileo

Isaac Newton

John Nash

Footballers

Tony Cascarino

Paul Gascoigne

• “I’ve learnt a lot...erm I guess about mental health it happens to a lot of people and things like... I thought I was abnormal, especially when I was down I thought what is wrong with me erm and [therapist] would always say well would you think somebody was normal if they had green eyes, and you’d be like yeah, and she’d say like... well more people have mental health problems than have green eyes” (8)

• “…all these thoughts, I was thinking when I felt fine, oh my god they’re crazy but

[therapist] helped me to see that the thoughts weren’t crazy, after looking at what happened” (1)

Common Treatment Strategies

• Advantages and disadvantages

• Normalisation and formulation

• Evidence for and against

• Explore meaning / downward arrows

• Modify environment

• Belief restructuring:

– Historical review

– Meaning of event

– Continuum

– Evidence, data log

• List alternative explanations

– Conviction ratings

– Pie chart

– Refer to feelings and behaviour

Common Treatment Strategies

• Behavioural experiments:

– Drop safety behaviours

– Exaggerate and drop

– Attentional focus

– Test reality

– Practical stuff

– Test alternatives

– Monitoring

– Symptom induction

– Surveys

• Metacognitive

– beliefs (e.g. positive/negative beliefs about paranoia/rumination/worry)

– strategies (e.g. postponing perseverative processing)

– attentional strategies (e.g. external focus)

• “We could test out our predictions, and like look for other explanations like, there was some exercises in the CBT that I could do...so eventually I’d feel, like I’d get a de-escalating feeling of anxiety” (1)

• “I think the evidence thing’s kind of good, sort of it is real and you have to sort of work out well, is it likely to be real. Like if you think, say, people taking thoughts out of my head, and erm, it’s sort of well what’s the proof that they are” (2)

Intervention: Delusions

• Identify thoughts, feelings & behaviour

• Evaluate advantages and disadvantages

• Evaluate thoughts:

– evidence for and against

– generate alternative explanations

– advantages & disadvantages

• Education

– anxiety, intrusions, metacognition,

– reasoning biases, thinking errors, selective attention

• Behavioural experiments

Advantages

Makes me feel special

Keeps my belief in a soulmate

Makes life feel special

Disadvantages

Frustration when Richard and I do not meet.

Causes difficulties with present partner

Has got me into trouble with the police in the past

My psychiatrist thinks this is a problem

It upsets my daughter a lot

I’m distraught when Richard tells me he is not in love with me

Anger towards Richards wife

Unable to go away for the weekend as need to stay near house in case Richard decides to come and see me

Evidence for

“The neighbours are going to attack me”

Evidence against

“The neighbours are going to attack me”

There are rowdy noises from next door

I have been assaulted by other people in the past

They can read my mind

I have seen them 3 times this week and they haven’t attacked me

I have never been assaulted by anyone from my street

I have never seen the neighbours be violent to anyone

I don’t think they are going to attack me when I am drunk or when I am with other people

Evaluating interpretations

The rowdy noises from next door are due to:

Initial belief: The neighbours want to attack me

The neighbours are having a party

The neighbours are having an argument

The neighbours are making noises to wind me up

I am imagining the noises

The noises are being beamed into the house from outer space

10%

0%

Stress, lack of sleep & beliefs are making me misinterpret noises 25%

80%

25%

50%

50%

Interpretations of Voices

• mediate distress

• identify

• use modified DTR

• use questionnaires

• use interviewing

• use downward arrows to access personal meaning

• use content

• use qualities of voice

Interpretations of Voices

• evaluate by

• use of list of interpretations

• generate alternative interpretations

• relate to normalising information

• rate & rerate belief each session

• use diaries / monitoring

» include how related were the voices to your thoughts or worries or yourself

Interpretations of Voices

• Evaluating...

• examine evidence for and against

» including content

» use shadowing

» compatibility of modulators

• behavioural experiments

» drop/modify safety behaviours

» manipulate attentional biases

» control

Interpretations of Voices

• encourage one to be internally generated

• provide information re: research

• behavioural experiments using subvocalisation

• analysis of voice content in relation to thoughts

• education re: intrusive thoughts

• identify metacognitive beliefs

• challenge metacognitive beliefs

Video

Content of Voices

• Can mediate distress

• Identify using:

– modified DTR

– shadowing

– role play

– diaries

Content of Voices

• Challenge using:

– link between thoughts and voices

– evidence for and against

– alternative explanations

– role play

– flashcards

Content of Voices & Schema

• Content of voices often related to experience

• bullying

• sexual abuse / rape

• worthlessness

• evil

• guilty

• threat

Content of Voices & Schema

• Challenge using Padesky’s (1994) techniques:

– continuum methods

– surveys

– historical test

– positive data logs

Why homework?

The rationale for homework

• The idea that homework enhances therapy should be replaced by the idea that therapy enhances homework .

Secondary gains of homework

• active

• achievement

• collaborative nature of the therapeutic relationship

• empowerment

6 golden rules for maximising homework compliance

• Decide work to be done jointly.

• Clearly identify the rationale for doing the homework.

• Check out obstacles.

• Make the homework meaningful but achievable.

• Establish prompts.

• Begin the use of homework from the first session.

• “I feel if I hadn’t done the homework that I had, then, and showed up to the sessions as well, I think it would have taken me a lot longer” (1)

• “…when I first like you know got told I was gonna have CBT you just expect you get better but it doesn’t, there’s a lot of like, you got a put a lot in yourself to get a lot out really” (7)

• “So once we had worked out that I was actually doing it right I could do it by myself”

(1)

Behavioural experiments

• A powerful way to test alternative belief derived from verbal testing

• Facilitates ‘gut’ level change

• Links behaviour with personal meaning

• Specifically targeted - increases efficiency and effect

• Wider range of uses

Behavioural experiments

• Can include:

– Observations

– Surveys

– Acting ‘as if’

– Hypothesis testing (A/B)

– Increasing / Decreasing responses

– Symptom induction

– Role plays

Issues of design

• Be collaborative

• Motivation to complete them

• Practical implementation

‘People can hear my thoughts’

• Behavioural experiments

– Drop safety behaviours

– Suppression vs. counter-suppression

– Recording

– Deliberate broadcasting to provoke responses

– Surveys

Principles of Cognitive Therapy

A cognitive model is required from which to empirically derive effective treatments:

FORMULATE USING MODEL

• What are you concerned about?

SHARE A GOAL

• You are not mad, you are normal:

NORMALISE

• Either it is real or you believe it to be real:

SIT ON A COLLABORATIVE FENCE

• How you appraise events contributes to distress:

EVALUATE USING E-T-F-B

• It’s not always what you think, sometimes it’s how you think

MODIFY CONTROL STRATEGIES

• Test it out – drop your safety behaviours:

EXPERIMENT IN & OUT OF SESSION

Tips

• Important to relate to goals (usually emotional change or changing ‘what I do’ to improve QoL)

• Use match between appraisal and emotion, and emotion and behaviour

• Only draw in arrows with agreement – otherwise investigate relationships

• Normalise the ‘story’

• Use arrows to plan treatment

Tips

• Agree a shared goal first and foremost

• Explicit structure and labels

• Focus on specifics, not general

• Leave plenty of time for ‘between session tasks’

CBT for psychosis

• NICE guidelines say at least 16 sessions over at least 9 months

• Numerous meta-analyses in support (BUT as adjunct to antipsychotics in most participants)

• Aims to reduce distress and improve quality of life

Inclusion criteria

• 1) either meet ICD-10 criteria for schizophrenia, schizoaffective disorder or delusional disorder or meet entry criteria for an Early Intervention for Psychosis service (operationally defined using PANSS) in order to allow for diagnostic uncertainty in early phases of psychosis

• 2) either have at least 6 months without antipsychotic medication and experiencing continuing symptoms OR never have received antipsychotics and be currently refusing

• 3) score at least 4 on PANSS delusions or hallucinations or at least 5 on suspiciousness/persecution, conceptual disorganisation or grandiosity

Measures

• Symptoms:

– PANSS

– Psychotic Symptom Rating Scales

(PSYRATS; Haddock, McCarron, Tarrier and

Faragher, 1999).

• Recovery

– A user-defined measure of recovery (QPR;

Neil et al., 2009)

• Functioning

– PSP

Allocation

Follow-Up

Analysis

CONSORT diagram

Referred (n = 43)

Assessed for eligibility (n=

26)

Enrollment

Allocated to intervention

(n= 20)

Received allocated intervention

(n= 19, 1 withdrew after 1 session)

Assessed n =17 declined n = 1 withdrew n = 2

Analysed (n= 20)

Excluded from analysis

(n=0)

Last observation carried forward (LOCF) at end of treatment analysis (n = 3)

LOCF at follow up analysis

(n = 5)

Excluded (n= 6)

Not meeting inclusion criteria

(n= 5)

Refused to participate

(n= 1)

Patient characteristics

• Gender

– Male N = 10

– Female N = 10

• Age

– Mean = 26

– Range 16 - 56

• Ethnicity

– White British N = 16

– Black African N = 1

– Black Caribbean N = 1

– Other N = 2

Diagnosis

• Schizophrenia N = 15

• Schizoaffective Disorder N = 4

• Delusional Disorder N = 1

• Disabling hallucinations N = 13

• Disabling delusions N = 17

• Both delusions and hallucinations N = 10

CT

• 8 therapists contributed to the delivery of

CT within the trial.

• The number of participants treated by each ranged between 1 and 10.

• participants received a mean of 16.7 sessions (S.D. = 7.26; range 1 to 26)

• Acceptability: no participant not attending any sessions, and 19/20 receiving 6 or more sessions

Effect size analyses (Cohen’s d)

Variable Baseline to end of treatment

0.87

PANSS positive

PANSS negative

PANSS general

PANSS total

1.00

0.51

0.85

PSYRATS delusions 0.98

PSYRATS voices 0.56

Baseline to 6 month follow up

1.05

0.77

1.06

1.23

0.99

0.79

PSYRATS total 0.90

1.07

PANSS total – mean scores at baseline, end of treatment and follow up

A significant difference from baseline to end of treatment was identified

(p = 0.001)

A significant difference from baseline to follow up was identified (p =

.0001)

45

39.55

40

35

29.05

30

25 21.88

20

15

10

5

0 baseline (SD=11.9) end of treatment

(SD=19.1)

6 month follow up

(SD=17.1)

Secondary outcomes

PANSS positive – mean scores at baseline, end of treatment and follow up

A significant difference from baseline to end of treatment was identified

(p = 0.01)

A significant difference from baseline to follow up was identified (p =

.001)

14

12

10

8

2

0

6

4

11.75

7.65

5.94

baseline (SD = 4.74) end of treatment (SD =

7.37)

6 month follow up (SD =

5.99)

Secondary outcomes

PSYRATS delusions – mean scores at baseline, end of treatment and follow up

A significant difference from baseline to end of treatment was identified

(p = 0.0001)

A significant difference from baseline to follow up was identified (p =

.001)

16

14

12

10

8

6

4

2

0

14.7

6.45

5.23

baseline (SD=6.66) end of treatment

(SD=7.07)

6 month follow up

(SD=6.3)

Secondary outcomes

PSYRATS voices – mean scores at baseline, end of treatment and follow up

A significant difference from baseline to end of treatment was identified

(p = 0.02)

A significant difference from baseline to follow up was identified (p =

.003)

25

19.35

20

15

10

5

0

10.81

9.48

baseline (SD=15.02) end of treatment (13.55) 6 month follow up

(12.34)

Variable

QPR total

PSP total

Secondary outcomes

Pre treatment:

Mean (SD)

Post

Treatment:

Mean (SD)

Follow up:

Mean

(SD)

Pre- treatment to posttreatment t p d 95% CI t

Pre-treatment to follow-up p d 95% CI

48.83

(15.69)

57.22

(18.59)

60.96

(18.80)

-1.69

.110

.41

0.09,

0.90

-2.50

.024

0.65

0.08,

1.11

47.4

(13.80)

56.45

(18.37)

66.05

(18.31)

-2.44

.025

0.54

0.07,

1.01

-3.99

.001

0.87

0.34,

1.37

Good and poor clinical outcomes.

25%+ Decrease on PANSS = Good clinical outcome

25% +Increase on PANSS = Poor clinical outcome

Table 2. % decrease on PANSS total scores at end of therapy and follow up

Total N 0 – 24% increase

0% - 24% reduction

25% - 49%

Reduction

End of therapy

20 3 7 3

50% - 74% reduction

75% -

100% reduction

5 2

6 month follow up

20 2 7 1 6 4

Secondary outcomes: initiation of antipsychotic medication

18

16

14

12

10

8

6

4

2

0

0

Started on anti psychotic medication during therapy

3

17

Started on anti psychotic medication post therapy

Not started on anti psychotic medication

Predictors at 9 months

BAPS: negative change

PANSS total change

.465*

IVI: metaphysical change

IVI: control change

Age

DI

DUP

Number of sessions

Gender

-.187

.255

.443

-.774**

-.307

-.096

.000

PSYRATS delusions change

PSYRATS voices change

.426

-.078

.038

.277

.388

-.295

-.817**

-.476

-.026

-.018

.707**

-.529*

-.017

.127

-.083

-.152

Predictors at 15 months

BAPS: negative change

PANSS total change

.647**

IVI: metaphysical change

IVI: control change

Age

DI

DUP

Number of sessions

Gender

-.314

.088

-.318

-751**

-.377

0.22

-.038

PSYRATS delusions change

PSYRATS voices change

.468* -.280

-.096

.318

.260

-.348

-717**

-.368

.002

-.024

.470*

-.385

.036

.089

-.007

-.149

Limitations

• Pilot study

– Small (N = 20)

– No control group

– No randomisation

– Rater bias?

– LOCF (but only one condition)

ACTION: Assessing Cognitive

Therapy Instead Of Neuroleptics

• Two site single blind RCT with two conditions

(CT plus TAU vs. TAU) for people with psychosis not taking antipsychotic medication

(due to refusal or discontinuation)

• Assessments are 3 monthly following the initial baseline assessment (i.e. at baseline, 3, 6, and 9 months)

• Follow-up assessments are at 12, 15 and 18 months

• n=74

Baseline PANSS data

PANSS subscale

PANSS positive total

PANSS negative total

PANSS general total

PANSS total

Mean

(S.D)

20.89

(4.91)

14.31

(4.61)

36.18

(7.70)

71.55

(13.76)

Reasons for not taking antipsychotics

Antipsychotic naïve: discontinued ratio

Reasons for not taking anti-psychotic medication

Side effects

Philosophical view on psychosis – disagrees with the medical model/ preference for psychological treatment

Health reasons including pregnancy

Symptoms are unresponsive to anti-psychotic medication

Disagrees with diagnosis

Other

Data unable to be captured

34:40

23 (31.08)

15 (20.27)

5 (6.76)

4 (5.41)

6 (8.11)

16 (21.62)

5 (6.76)

• Treatment options for first episode psychosis

– If the child or young person and their parents or carers wish to try psychological interventions

(family intervention with individual CBT) alone without antipsychotic medication, advise that psychological interventions are more effective when delivered in conjunction with antipsychotic medication. If the child or young person and their parents or carers still wish to try psychological interventions alone, then offer family intervention with individual CBT. Agree a time limit(1 month or less) for reviewing treatment options, including introducing antipsychotic medication. Continue to monitor symptoms, level of distress, impairment and level of functioning, including educational engagement and achievement, regularly.

1.3.27 CBT should be delivered on a one-to-one basis over at least 16 planned sessions (although longer may be required) and: follow a treatment manual* so that

- children and young people can establish links between their thoughts, feelings or actions and their current or past symptoms, and/or functioning

- the reevaluation of the child or young person’s perceptions, beliefs or reasoning relates to the target symptoms also include at least one of the following components:

- normalising, leading to understanding and acceptability of their experience

- children and young people monitoring their own thoughts, feelings or behaviours with respect to their symptoms or recurrence of symptoms

- promoting alternative ways of coping with the target symptom

- reducing distress

- improving functioning.

Case study

• 1-8

– Problems and goals (confidence, self-esteem, low mood and self-harm, voices, low motivation)

– Formulation

– Continuum for low self-esteem

– Evidential analysis of self-critical thoughts

– Positive imagery

– Survey / results (judged, relationship, employ)

Experiences that worry me

Social situations

Voices

What I make of it

I am not good enough

I must harm myself

Voices are bullies

Others will harm me

What I do

Try to stay in control of thoughts

Isolate self and withdraw

Negative comparisons

Rituals

Daydreaming / dissociation

What I make of the self / world

I am different

I am unimportant and worthless

Need to be alert for danger

Other people cannot be trusted

Others will leave and reject me

Early experiences

Family criticism

Never fit in

Severe bullying at school and work

Wrongful arrest and harassment

How I feel

Low mood

Hopeless

Anxiety

Anger

Case study

• 9-11

– Revisit goals

– Negative comparisons

– I’m a failure

– Activity for mood

• 12-15

– Daydreaming and dissociation (normalising; pros/cons; diary; modified GAD model)

– Voices

Case study

• 16-18

– PTSD (grounding, attentional focus, reconsider meaning)

• 19-22

– Social anxiety (stop post-mortems, anticipation > event, stop safety behaviours, external focus, update image)

What I do

Arrive late

Avoid eye contact

Only speak to people I know

Speak with hand over mouth

Doodle/fidget

Hunch up and try to disappear trigger

Social situations

Negative thought

Others will judge me

Others will reject me

Image of self

Weak

Vulnerable

Hunched

Ugly

Very skinny

Unconfident

Shaky

How I feel

Anxiety

Tense

Palpitations

Sweaty

Shaky

Case study

• Progress:

– I am good enough 0% 80%

– Social confidence

– I am different

10% 70%

100% 50% (neutral)

– I’m as important as others 0% 80%

– No flashbacks, no self-harm, no suicidal thoughts

– Voices only at night and managable

– Getting married

– Doing postgraduate course

Does CBT work for transition?

12 month outcomes

Study or Subgroup

ADDINGTON2011A

MORRISON2004

MORRISON2011

PHILLIPS2009

VAN DER GAAG2012

CBT SC

Events Total Events Total Weight

Risk Ratio

M-H, Random, 95% CI

7

7

9

0

2

16

26

95

29

75

10

6

20

3

5

15

16

93

19

86

2.5%

9.0%

24.4%

24.3%

39.7%

0.13 [0.01, 2.40]

0.25 [0.05, 1.12]

0.69 [0.27, 1.72]

0.76 [0.30, 1.93]

0.52 [0.25, 1.06]

Total (95% CI) 241 229 100.0%

Total events 25 44

Heterogeneity: Tau² = 0.00; Chi² = 2.77, df = 4 (P = 0.60); I² = 0%

Test for overall effect: Z = 2.57 (P = 0.01)

0.55 [0.35, 0.87]

Risk Ratio

M-H, Random, 95% CI

0.5

0.7

1 1.5

2

Favours CBT Favours SC

Does CBT+AP work for transition?

Study or Subgroup

CBT + risperidone SC

Events Total Events Total Weight

Risk Ratio

M-H, Random, 95% CI

MCGORRY2002

PHILLIPS2009 7

6 24

27

10

6

17 56.2%

19 43.8%

0.42 [0.19, 0.94]

0.82 [0.33, 2.06]

Risk Ratio

M-H, Random, 95% CI

Total (95% CI) 51 36 100.0%

Total events 13 16

Heterogeneity: Tau² = 0.02; Chi² = 1.13, df = 1 (P = 0.29); I² = 11%

Test for overall effect: Z = 1.73 (P = 0.08)

0.57 [0.30, 1.08]

0.5

0.7

1 1.5

2

Favours CBT + risperidone Favours SC

Does CBT work for symptoms in

UHR?

Study or Subgroup

PHILLIPS2009

ADDINGTON2011A

MORRISON2004

MORRISON2011

CBT

Mean SD Total

2.8

5.2

2.9

5.6

10.5417

3.05001

14.88

15.54

Mean

SC

SD Total Weight

Std. Mean Difference

IV, Random, 95% CI

27

27

3.1

6.6

3

4.7

35 10.9286

2.99908

95 20.84

17.75

18

24

23

93

12.9%

15.1%

16.6%

55.4%

-0.10 [-0.70, 0.50]

-0.27 [-0.82, 0.29]

-0.13 [-0.65, 0.40]

-0.36 [-0.64, -0.07]

Std. Mean Difference

IV, Random, 95% CI

Total (95% CI) 184

Heterogeneity: Tau² = 0.00; Chi² = 0.94, df = 3 (P = 0.82); I² = 0%

Test for overall effect: Z = 2.48 (P = 0.01)

158 100.0% -0.27 [-0.49, -0.06]

-1 -0.5

0 0.5

1

Favours CBT Favours SC

What do service-users want?

60

50

40

30

20

10

0

PACE

McGorry et al. 2002

[CBT plus risperidone]

EDIE

Morrison et al. 2004

[CT]

PRIME

McGlashan et al. 2006

[Olanzapine]

EDIE-2

Morrison et al. 2012

[CT]

NICE draft guideline:

Psychosis and schizophrenia in children and young people: recognition and management

• Treatment options for symptoms not sufficient for a diagnosis of psychosis or schizophrenia

• When transient or attenuated psychotic symptoms or other mental state changes are not sufficient for a diagnosis of psychosis or schizophrenia, consider:

– treatments recommended in NICE guidance for any recognised conditions such as anxiety, depression, emerging personality disorder or substance misuse, or

– individual or family cognitive behavioural therapy (CBT) to decrease distress (delivered as set out in recommendation

1.3.27). [1.2.5]

• Do not offer antipsychotic medication for psychotic symptoms or mental state changes that are not sufficient for a diagnosis of psychosis or schizophrenia, or with the aim of decreasing the risk of psychosis. [1.2.6]

EDIE-2 vs ACTION: Stigma

t ARMS

Mean (SD)

Psychosis

Mean (SD)

P 95% CI

Self as abnormal 13.56 (2.53)

Expectations 10.43 (2.70)

Shame

Depression

Social anxiety

5.69 (1.36)

9.73 (4.48)

41.18

(16.98)

13.56 (3.33)

10.95 (2.64)

5.88 (1.42)

9.61 (4.73)

40.77 (18.03)

-.001

.999

-.760 - .759

-1.531

.127

-1.20 - .150

-.979

.187

.172

.328

.851

.864

-.562 - .189

-1.09 - 1.32

-4.33 - 5.16

EDIE-2 vs ACTION: Stigma

BDI SIAS

ARMS Psychosis ARMS Psychosis

Self as abnormal

Expectations

Shame

.471**

.452**

.332**

.375**

.543**

.486**

.405**

.422**

.325**

.376**

.426**

.442**

Stigma

30

25

20

15

10

5

0 baseline 6 12 24

CT

Monitoring

• “I never expected it to be a wondercure, and that Edie 2 at the end of it I was going to feel normal again, but in terms of looking at the horrible side of mental health, I feel as though they’ve confirmed that I’m not going down that road, and that’s helped me feel better inside I guess”

(m2)

Summary

• Minimise harm from medication, especially if no benefits

• Promote choice and alternatives

• Normalise / understand psychosis from a psychosocial perspective

• Reduce distress with CBT

• Promote recovery

• Promising for preventing first episodes of psychosis and reducing symptoms in UHR

• Work in genuine partnership with young people

Conclusions

• More research required

– Who benefits from antipsychotics

– Who benefits from CBT

– Alternatives evaluated in comparison to antipsychotics

– Other alternatives

• Reasons for optimism

– CBT reduces transition and symptoms in ARMS

– CBT is encouraging as an alternative to antipsychotics for established psychosis

– CBT without antipsychotics seems to work well for early phases of psychosis / young people

• “I feel if I hadn’t done the homework that I had, then, and showed up to the sessions as well, I think it would have taken me a lot longer” (1)

• “…when I first like you know got told I was gonna have CBT you just expect you get better but it doesn’t, there’s a lot of like, you got a put a lot in yourself to get a lot out really” (7)

• “I think what I struggled with was the fact that I was having to look at myself and em, and then there was like homework that came with it you know, and I struggled with that for a while purely and simply because I was having to look at myself” (t8)

• “To be honest there would have been times where there was no way I would have engaged with it or benefited from it…think you’ve got to be ready and motivated for it cos there is quite a lot of thinking and you need to be fairly open minded.” (3)

Download