LIFE’S ALL ABOUT CHANGE DSM 5, ICD-10 Codes, and ASAM Levels Of Care OVERVIEW Introduction DSM Revision Process General Changes to DSM-5 New and Revised Disorders ICD 10 and the DSM-5 Implications BEFORE THE DSM 1917- APA had a diagnostic system with 59 mental disorders 1934 – APA made revisions to classifications 1940’s – Following WWII, military clinicians found little practical use for the APA’s diagnostic system 1948 – 6th edition of International Classification of Diseases published 1948 – APA began development on the DSM 1st Edition 1952 Queen Elizabeth II succeeded King George VI to the English throne DSM – 1 published with 106 Diagnosis 1968 U.S. President Lyndon B. DSM – 2 published with Johnson signs the Civil Rights Act of 1968 182 Diagnosis Conformed to the ICD system Green Bay Packers win Super Bowl II Hey Jude is #1 on Billboard 1980 Ronald Regan is elected President Bjorn Borg defeated John McEnroe in Wimbledon Georgia is NCAA Football Champions Ted Turner launches CNN Another One Bites The Dust by Queen #1 Billboard DSM – III published with 265 Diagnosis Retained conformity to the ICD system More emphasis on “medical model” Multi-axial system that focused on symptoms rather than causes. 1987 Dow Jones closes above 2000 for the first time DSM – III R published Increased reliability and validity First Anti-Smoking campaign airs with Yul Brynner Living on a Prayer is #1 on the Billboard Increased diagnosis to 292 1994 Nancy Kerrigan is attacked by Tonya Harding’s bodyguard Lorena Bobbitt went to trial 6.6 Earthquake hit LA Bill Clinton becomes the 42nd President Forrest Gump is released DSM – IV published Goal to retain conformity with ICD 9 Changes included a detailed system of diagnostic criteria Diagnoses increased to 365 2000 The Millennium/Y2K DSM – IV R published No change in number of Air France Flight 4590 Concorde crashes after takeoff killing all 109 passengers NY Yankees wins 3rd straight World Series Championship diagnoses Increase of 800% from 182 to 365 from 1952 to 2000 DSM-5 REVISION TIMELINE Year Activity 1999 Pre-Planning 2006 Task force formed 2008-2010 Literature review and data Analysis April 2010-December 2011 Field trials in large, academic medical centers October 2010 – February 2012 Field trials in routine clinical practices July 2012 Final draft of DSM 5 for APA review December 2012 Draft finalized May 20, 2013 Publication date PRINCIPLES TO GUIDE DSM-5 REVISION PROCESS 1) Highest priority is “clinical utility” 2) Recommendations should be based on research evidence 3) When possible, continuity with the DSM – IV should be maintained 4) There should be no pre-determined constraints on changes from DSM-IV in areas where the manual’s organization and criteria were problematic CONCERNS WITH THE REVISION PROCESS Empirical support Field trials Dimensional assessments Low reliabilities Possible boundary issues with pharmaceutical companies Kappa Values (Target >= 0.6 for diagnostic reliability ) DSM-5 DSM-IV DSM-III ADHD 0.61 0.59 0.50 Alcohol use disorder 0.40 0.80 Antisocial PD Attenuated psychosis syndrome <0.01 Autism spectrum disorder 0.69 Binge eating disorder 0.56 Bipolar I disorder 0.54 Bipolar II disorder 0.40 Borderline PD 0.55 Conduct DO 0.48 Disruptive mood dysregulation disorder (DMDD) 0.50 Generalized anxiety disorder 0.85 0.01 0.57 0.61 0.20 0.65 0.72 Major depressive disorder 0.32 0.59 0.80 Major neurocognitive disorder 0.50 Mild neurocognitive disorder 0.50 Mixed anxiety depression (not in DSM 5) 0.06 Obsessive-compulsive PD 0.31 Oppositional defiant disorder (OD) 0.41 0.55 0.66 PTSD 0.67 0.59 0.55 Schizophrenia 0.46 0.76 0.81 Suicidal self-injury (not in DSM 5) -0.03 GENERAL CLASSIFICATION CHANGES REMOVAL OF MULTIAXIAL SYSTEM New non-axial documentation of diagnosis Combines the former Axes I, II, III Separate “notations” for psychosocial and contextual factors (formerly Axis IV) Separate “notations” for disability (formerly Axis V) No more GAF score NEW DIAGNOSTIC CODES Diagnostic codes changed from numeric to alphanumeric October 1, 2015 all insurance companies will require the reporting of ICD 10 codes No longer numeric codes; alphanumeric OCD was 300.3 now it is F42 REMOVED NOS Replaced NOS with: “Other specified _____________ disorder” “Unspecified ________________ disorder DSM-5 ORGANIZATIONAL STRUCTURE Section I: DSM-5 Basics Introduction & information on how to use the updated manual Section II: Essential Elements: Diagnostic Criteria & Codes Outlines the categorical diagnosis Section III: Emerging Measures and Models Include conditions requiring further research along with cultural formulations, glossary, and names of individuals involved in developing DSM-5 Appendix DSM-5 TABLE OF CONTENTS 1. Neurodevelopment D/Os 2. Schizophrenia Spectrum & Other Psychotic Disorders 3. Bipolar & Related Disorders 4. Depressive D/Os 5. Anxiety D/Os 6. Obsessive-Compulsive & Related D/Os 7. Trauma & Stressor-Related D/Os 8. Dissociative D/Os 9. Somatic Symptom & Related D/Os 10. Feeding & Eating D/O 11. Elimination D/O 12. Sleep-Wake D/O DSM-5 TABLE OF CONTENTS 13. Sexual Dysfunctions 14. Gender Dysphoria 15. Disruptive, Impulse-Control, & Conduct D/Os 16. Substance-Related & Addictive D/Os 17. Neurocognitive D/Os 18. Personality D/Os 19. Paraphilia D/Os 20. Other Mental D/Os 21. Medication-Induced Movement D/Os & Other Adverse Effects of Medication 22. Other Conditions That May Be a Focus of Clinical Attention NEW AND REVISED DISORDERS NEURODEVELOPMENTAL DISORDERS Intellectual Disability (Intellectual Developmental Disorder) Name change Severity determined by adaptive functioning rather than IQ score Communication D/O Include language disorder Speech sound disorder Childhood-onset fluency disorder Social pragmatic communication disorder NEURODEVELOPMENTAL DISORDERS Autism Spectrum Disorder (F84.0) Encompasses autistic disorder, Asperger’s disorder, childhood disintegrative disorder, and pervasive developmental disorder NOS Symptoms in two core areas: 1. Deficits in social communication & social interaction 2. Restricted repetitive behaviors, interests, & activities NEURODEVELOPMENTAL DISORDERS Attention-Deficit/Hyperactivity Disorder (F90._) Two symptom domains: inattention & hyperactivity/impulsivity Onset prior to age 12 Adults lower symptom threshold Specific Learning Disorders (F81.__) Motor Disorders SCHIZOPHRENIA SPECTRUM AND OTHER PSYCHOTIC DISORDERS SCHIZOPHRENIA (F20.9): 2 criterion A symptoms (one must include 1-3) 1. Delusions 2. Hallucinations 3. Disorganized speech 4. Grossly abnormal psychomotor behavior 5. Negative symptoms Eliminated schizophrenia subtypes Recommended use of dimensional assessment in Section III SCHIZOPHRENIA SPECTRUM AND OTHER PSYCHOTIC DISORDERS SCHIZOAFFECTIVE DISORDER (F25._) A mood episode is present for majority of the disorder’s duration DELUSIONAL DISORDER (F22) No longer requires that delusions be “non-bizarre” A specifier for bizarre delusions has been added CATATONIA (F06.1) A specifier that can be added BIPOLAR AND RELATED DISORDERS BIPOLAR I and BIPOLAR II DISORDERS (F31.__) Criterion A emphasizes changes in activity and energy, as well as mood. Removed “Mixed Episode” and added “With Mixed Features” OTHER SPECIFIED BIPOLAR AND RELATED DISORDERS (F31.89) Anxious Distress Specifier DEPRESSIVE DISORDERS DISRUPTIVE MOOD DYSREGULATION DISORDER (DMDD) (F34.8) Temper outbursts involving yelling, rages, or physical aggression Overreacting to common stressors Temper outbursts occurring on average 3 or more times a week for at least 12 months (not symptom-free for more than 3 months at a time) Children age 6 to 18 DEPRESSIVE DISORDERS MAJOR DEPRESSIVE DISORDER (F32._ or F33._) Removed bereavement criterion New “with mixed features” and “with anxious distress” specifiers PERSISTENT DEPRESSIVE DISORDER (F34.1) PREMENTSTURAL DYSPHORIC DISORDER (N94.3) ANXIETY DISORDERS GENERALIZED ANXIETY DISORDER (F41.1) SPECIFIC PHOBIA (F40.___) PANIC DISORDER (F41.0) AGORAPHOBIA (F40.00) SOCIAL ANXIETY DISORDER (SOCIAL PHOBIA) (F40.10) SEPERATION ANXIETY DISORDER (F93.0) SELECTIVE MUTISM (F94.0) OBSESSIVE-COMPULSIVE AND RELATED DISORDERS OBSESSIVE COMPULSIVE DISORDER (F42) BODY DYSMORPHIC DISORDER (F45.22) TRICHOTILLOMANIA (Hair Pulling) (F63.2) EXCORIATION (Skin Picking) (L98.1) HOARDING (F42) TRAUMA & STRESS-RELATED DISORDERS REACTIVE ATTACHMENT DISORDER (F94.1) ADJUSTMENT DISORDER (F43.__) ACUTE STRESS DISORDER (F43.0) PTSD (F43.10) TRAUMA & STRESS-RELATED DISORDERS PTSD: CRITERION A – TRAUMATIC EVENT Directly experiences the traumatic event Witnesses the traumatic event Learns that the Traumatic event occurred to a close family member or close friend or Experiences first-hand repeated or extreme exposure to aversive details of the traumatic event TRAUMA & STRESS-RELATED DISORDERS PTSD SYMPTOM CLUSTERS: Re-experiencing: spontaneous memories of the traumatic events, recurrent dreams, flashbacks or psychological distress Avoidance: distressing memories, thoughts, feelings or external reminders of the event Negative cognitions and mood: represents myriad feelings (e.g., distorted sense of blame of self or others, estrangement from others, diminished interest in activities, inability to remember key aspects of the event) Arousal: aggressive, reckless or self-destructive behavior, sleep disturbances, hypervigilance, or related problems SOMATIC SYMPTOM & RELATED DISORDERS Eliminated the term “somatoform” Drops centrality of “unexplained medical symptoms” The disorders: Somatic Symptom Disorder Illness Anxiety Disorder Conversion Disorder Psychological Factors Affecting Other Medical Conditions Factitious Disorder FEEDING AND EATING DISORDERS Feeding disorders: pica, rumination disorder, and avoidant/restrictive food intake disorder Anorexia Nervosa (F50.__) Bulimia Nervosa (F50.2) Binge Eating Disorder (F50.8) GENDER DYSPHORIA GENDER DYSPHORIA (F64._) Replaces the term “Gender Identity Disorder” Separated from Sexual Disorders Only diagnose if troubled by identification DISRUPTIVE, IMPULSE-CONTROL AND CONDUCT DISORDERS Oppositional Defiant Disorder (F91.3) Intermittent Explosive Disorder (F63.81) Conduct Disorder (F91._) Pyromania (F63.1) Kleptomania (F63.3) NEUROCOGNITIVE DISORDERS Major Neurocognitive Disorder Mild Neurocognitive Disorder Delirium NEUROCOGNITIVE DISORDERS EXAMPLES OF DEFICITS IN LEARNING AND MEMORY: Major: Repeats self in conversation, often within the same conversation, can’t keep track of short list of items when shopping or plans for day. Requires frequent reminders to orient to task at hand. Minor: Difficulty recalling recent events and increased reliance on list-making or calendar. Needs occasional reminders or re-reading to keep track of characters in a movie or novel. Occasionally may repeat self over a few weeks to the same person, loses track of whether bills have already been paid. PERSONALITY DISORDERS DSM 5 maintained all 10 personality disorder categories and criteria from DSM IV A new trait-specific model of personality disorders will be included in Section 3 to encourage further study. SUBSTANCE-RELATED & ADDICTIVE DISORDERS Alcoholic, Addict, Dependent? Why does it matter? Alcoholism ? Use Disorder Addiction Dependence These words carry beliefs and practitioner belief is a major factor in client improvement… …our belief and our doubt is often rooted in our paradigms. PARADIGM QUESTIONS What is the nature of alcoholism? "We're on the cusp of some major advances in how we conceptualize alcoholism. The focus now is on the large group of people who are not yet dependent. But they are at risk for developing dependence." Dr. Mark Willenbring, (formerly of NIAAA) PARADIGM QUESTIONS Are there different types of Alcoholism? Young Adult Subtype (31.5%) Young Antisocial Subtype (21%) Functional Subtype (19.5%) Intermediate Familial Subtype (19%) Chronic Severe Subtype (9%) Moss, Howard B., Chen, Chiung M., and Yi, Hsiao-Ye (2007). Subtypes of alcohol dependence in a nationally representative sample. Drug and Alcohol Dependence, 91, issues 2-3, Pages 149-158 RESEARCH SAYS... • In 1953, Straus and Bacon published the first large study of college drinking behavior. • Twenty seven years later, Fillmore (1974, 1975) followed up with the problem drinkers in Straus and Bacon’s study. • She found many heavy problem drinkers in college were drinking small quantities with no problems 27 years later RESEARCH SAYS... Can they return to low-risk drinking? Helger, et. al. (1985) followed people treated for alcoholism and found: Less than 2% of people with alcoholism returned to “stable moderate drinking” for more than 1-2 years Another 4.6% drank occasionally RESEARCH SAYS... Dawson’s 1996 National Alcohol Epidemiological study on a general population found: • Almost half of those ever qualifying for a DSM-IV dependence diagnosis later returned to drinking without problems • Rates varied greatly with time elapsed, age, and treatment status • The phenomenon occurred in each group, and for some, was sustained for at least two decades CAN THEY RETURN TO LOW-RISK DRINKING? What Is Alcoholics Anonymous’ View? “ …we have a certain type of hard drinker. He may have the habit badly enough to gradually impair him physically and mentally. It may cause him to die a few years before his time. “ Alcoholics Anonymous, Page 20-21 ALCOHOLISM Central Tenets… Characterized by loss of control Progressive Irreversible ALCOHOLISM AA laid the foundation But what about the real alcoholic? He may start off as a moderate drinker; he may or may not become a continuous hard drinker; but at some stage of his drinking career he begins to lose all control of his liquor consumption, once he starts to drink. “ “ Alcoholics Anonymous, page 20 AA was founded in 1935 ALCOHOLICS ANONYMOUS The Disease Concept “We believe, and so suggested a few years ago, that the action of alcohol on these chronic alcoholics is a manifestation of an allergy; that the phenomenon of craving is limited to this class and never occurs in the average temperate drinker. These allergic types can never safely use alcohol in any form at all; and once having formed the habit and found they cannot break it, once having lost their selfconfidence, their reliance upon things human, their problems pile up on them and become astonishingly difficult to solve” Alcoholics Anonymous, page xxviii DEPENDENCE The Dependence Paradigm was born… “Drug Dependence” had been introduced in diagnostic nomenclature by the WHO in 1968 but it did not yet have a separate identity. Vernon Johnson used “Harmful Dependence” as his first Phase of Alcoholism (I’ll Quit Tomorrow, 1973). DEPENDENCE Is the Concept “Alcohol Dependence” the same as “Alcoholism?” • Edwards suggested that dependence is made up of seven symptoms that lie on a continuum. • The further a person progresses, the less likely that person is to successfully return to drinking without problems. • Again, loss of control and irreversibility were not assumed. DEPENDENCE Is DSM-IV Dependence a Synonym for Alcoholism? What is required to have the diagnosis, “Alcohol Dependent in Full Sustained Remission”? 12 Months symptom-free (not abstinence) DEPENDENCE Is the Concept “Alcoholism” or Addiction” the same as “Dependence”? Dependence was never meant as a synonym for alcoholism/addiction as we understand it (loss of control). Meant to be a clinically useful tool for clinicians who accept alcoholism/addiction as an irreversible disease and those who do not. The field took the concept of “alcoholism” and the concept of “dependence” and assumed the new term was just a restatement of what we already held to be true. It was, in fact, different. DEPENDENCE Now Let’s Recap… The original concept of alcoholism centered on loss of control. The concept of dependence is much broader and does not require loss of control. It casts a “larger net.” Everyone with alcoholism (traditionally defined) will have dependence. Not everyone with dependence will have alcoholism (traditionally defined). ADDICTION Evolution: Initially referred to the presence of a withdrawal syndrome when use was stopped. It evolved to a pattern of compulsive use, loss of control over use, and often included negative consequences. ASAM DEFINITION OF ADDICTION Addiction is a primary, chronic disease of brain reward, motivation, memory and related circuitry. Dysfunction in these circuits leads to characteristic biological, psychological, social and spiritual manifestations. This is reflected in an individual pathologically pursuing reward and/or relief by substance use and other behaviors. ASAM DEFINITION OF ADDICTION Addiction is characterized by the inability to consistently abstain, impairment in behavioral control, craving, diminished recognition of significant problems with one’s behaviors and a dysfunctional emotional response. Like other chronic diseases, addiction often involves cycles of relapse and remission. Without treatment or engagement in recovery activities, addiction is progressive and can result in disability or death. WHAT IS DIFFERENT ABOUT THIS DEFINITION? The focus in the past has been generally on substances associated with addiction. The new definition clarifies that addiction isn't about drugs, it’s about brains. It is not the substance or the quantity or frequency of use that makes them an addict. Addiction is about what happens in the reward circuitry of the brain when exposed to a rewarding substance or behavior. WHY IS THIS DEFINITION IMPORTANT? It helps explain what is really happening with addiction and that the behaviors of addiction are understandable in the context of the alterations in brain function. DSM III-TR & IV PROBLEMS “Diagnostic Orphans”: Someone could meet 2 criteria for dependence and none for abuse The reliability of DSM IV dependence diagnosis is better than that of abuse Research fails to support that abuse is a prodromal phase of dependence. PROBLEM WITH THE TERM “DEPENDENCE” Most healthcare providers confuse the syndrome of dependence (as defined in the DSM-IV) and physiological dependence. To some the terms addiction or addict are stigmatizing WHY CHANGE THE CRITERIA? Research shows that the symptoms of substance use problems do not fall neatly into distinct criteria. The term dependence is misleading, since tolerance and withdrawal can be experienced with normal use of medications that affect the central nervous system. DSM-5 NEW CHAPTER NAME Substance Related and Addictive Disorders Gambling Disorder Moved from Impulse Control Disorder DSM 5 COMBINES ABUSE & DEPENDENCE Instead of having substance abuse or dependence you will have a substance use disorder SUBSTANCE USE DISORDER DEFINED A maladaptive pattern of substance use leading to clinically significant impairment or distress, as manifested by 2 or more of the following, occurring within a 12 month period. SUBSTANCE USE DISORDER DEFINED 1. Recurrent substance use resulting in failure to fulfill major role obligations. 2. Recurrent substance use in situations where it is physically hazardous 3. Continued substance use despite having social or interpersonal problems SUBSTANCE USE DISORDER DEFINED 4. Tolerance, as defined by either of the following: A need for markedly increased amounts of the substance to achieve intoxication or the desired effect. Markedly diminished effect with continued use of the same amount of the substance. Tolerance not counted if taking meds as directed under medical supervision. 5. Withdrawal, as manifested by either of the following: The characteristic withdrawal syndrome for the substance The same or closely related substance is taken to relieve or avoid withdrawal symptoms. Withdrawal isn’t counted if taking meds correctly under medical supervision. SUBSTANCE USE DISORDER DEFINED 6. 7. 8. 9. 10. The substance is often taken in a larger amounts over a longer period than was intended. Persistent desire or unsuccessful efforts to cut down or control substance use A great deal of time is spent in activities necessary to obtain the substance, or recover from its effects Important social, occupational, or recreational activities are given up or reduced Continued use despite persistent or recurrent physical or psychological problems SUBSTANCE USE DISORDER DEFINED 11. Craving or a strong desire or urge to use a specific substance. A CAT CALLED CRAVING A CAT CALLED CRAVING A CAT CALLED CRAVING 1. 2. 3. 4. 5. 6. Craving is misunderstood Craving grows over time It is a permanent relationship Myth: Craving will stop growing Myth: Cutting back will stop craving Myth: Substituting other items will stop craving A CAT CALLED CRAVING In a relationship with a big, ever growing, mean, angry, immortal, telepathic cat called craving 2. It is a permanent relationship 3. Solutions to cope with Craving 1. Don’t feed the cat Don’t try substitutions Ask for help from others Don’t go down the milk aisle Don’t go to “milk festivals” DETERMINING SEVERITY 0-1 criteria= No Disorder 2-3 criteria= Mild Disorder 4-5 criteria= Moderate Disorder 6 or more criteria= Severe Disorder ICD-10 CODES EXAMPLES Alcohol Use Disorder Mild – F10.10 Moderate – F10.20 Severe – F10.20 Cannabis Use Disorder Mild – F12.10 Moderate – F12.20 Severe – F12.20 ANALYSES RELATED TO DEVELOPMENT OF DSM-5 IN 663 PATIENTS Fit statistics indicate: Abuse and Dependence criteria fit better as a unified single dimension than as separate dimensions 2. Legal Criterion does not add to diagnostic criteria and typically occurs when disorder very severe 3. Craving adds little to diagnostic accuracy but accords with ICD 1. NEW - CANNABIS WITHDRAWAL Irritability, anger, or aggression Nervousness or anxiety Sleep difficulty (e.g., insomnia, disturbing dreams) Decreased appetite or weight loss Restlessness Depressed Mood One of the following physical symptoms: stomach pain, shakiness/tremors, sweating, fever, chills, or headache WHY CLASSIFY GAMBLING DISORDER WITH SUBSTANCE USE DISORDERS? Strong comorbidity of SUD. “Pathological Gambling” Convincing genetic literature: “behavioral disinhibition”= measureable phenotype with high heritability that underlies SUD gambling: different manifestations of one underlying problem. Considerable evidence for shared neurobiology: Imbalance of motivation/reward systems vs inhibitory systems. CONCERNS ABOUT DSM 5 CHANGES Would significantly increase the number of people being diagnosed with addiction. 2. The APA has not allowed enough discussion regarding these changes (secondary gain). 3. It could create false epidemics and medicalication of everyday behavior. 4. Possible boundary issues between DSM panel members and the pharmaceutical companies. 1. OTHER DSM-5 is available as online subscription at PsychiatryOnline.org ASAM CRITERIA 12 years since last revision More user-friendly Compatible with DSM-5 Follows the treatment process Sections: Special Populations Tobacco/gambling Working with managed care Terminology focused on: Behavior Strengths, not pathology Goal for the ASAM Criteria to be a resource for screening and to determine the appropriate levels of care UNDERLYING CONCEPTS OF THE ASAM CRITERIA: INDIVIDUALIZED, CLINICALLYDRIVEN TREATMENT Source: The ASAM Criteria ASSESSMENT OF BIOPSYCHOSOCIAL SEVERITY AND LEVEL OF FUNCTION Dimension 1: Acute Intoxication and/or Withdrawal Potential Dimension 2: Biomedical conditions and complications Dimension 3: Emotional/Behavioral/Cognitive Conditions and Complications Dimension 4: Readiness to Change Dimension 5: Relapse/Continued Use/Continued Problem potential Dimension 6: Recovery Environment Source: The ASAM Criteria BIOPSYCHOSOCIAL TREATMENT TREATMENT MATCHING MODALITIES Motivate – Dimension 4 Manage – All Six Dimensions Medication – Dimensions 1, 2, 3, 5 Meetings – Dimensions 2, 3, 4, 5, 6 Monitor – All Six Dimensions Source: The ASAM Criteria ASAM LEVELS Level 0.5: Early Intervention Services Level 1: Outpatient Treatment (With & Without Withdrawal Management) Level 2: Intensive Outpatient and Partial Hospitalization (With & Without Withdrawal Management) Level 3: Residential/Inpatient Treatment (With & Without Withdrawal Management) Level 4: Medically-Managed Intensive Inpatient Treatment Source: The ASAM Criteria FOCUS ASSESSMENT AND TREATMENT What Does the Client Want? Does client have immediate needs due to imminent risk in any of six dimensions? Conduct multidimensional assessment Source: The ASAM Criteria FOCUS ASSESSMENT AND TREATMENT DSM-5 diagnoses? Multidimensional Severity/LOF Profile Which assessment dimensions are most important to determine Tx priorities Specific focus/target for each priority dimension What specific services needed for each dimension What “dose” or intensity of these services needed Where can these services be provided in least intensive, but “safe” level of care? What is progress of Tx plan and placement decision; outcomes measurement? Source: The ASAM Criteria REFERENCES American Psychiatric Association (APA). (2013). Diagnostic and statistical Manual of Mental Disorders (5th ed) DSM-5. Arlington,VA: American Psychiatric Association. American Psychiatric Association (APA). (2010). American Psychiatric Association DSM-5 development. Retrieved from http://www.dsm5.org/Pages/Default.aspx. 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