The Spinal Cord Honors Anatomy& Physiology for copying Spinal Cord • w/spinal nerves contain neural circuits that mediate some of your most rapid reactions to environmental changes Protective Structures • 2 types of CT coverings surround & protect delicate nervous tissue 1. bony vertebrae 2. tough CT meninges, w/cushion of CSF Meninges • 3 CT coverings that encircle spinal cord & brain: • Spinal meninges covers spinal cord • Cranial meninges covers brain Meninges Layers: Dura Mater “tough mother” most superficial layer made of dense, irregular CT continuous with cranial meninges forms sac from foramen magnum S2 • layer of adipose tissue between dura mater & wall of vertebral cavity (epidural space) • • • • • Middle Meninges: Arachnoid Mater • “spider-like” • deep to dura mater, superficial to pia mater • contiguous with cranial arachnoid • between dura & arachnoid = subdural space Innermost Meninges:Pia mater • • • • “delicate” thin, transparent CT adheres to spinal cord & brain between arachnoid & pia = subarachnoid space Spinal Tap • aka lumbar puncture • long needle inserted into subarachnoid space • adults: between L3 –L4 or L4 – L5 (inferior to lowest portion of spinal cord) • purpose: withdraw CSF for – diagnostic purposes – insert antibiotics/contrast media for myelography/ anesthetics/ chemotherapy Spinal Cord • cylindrical with flattening of its AP diameter • adults:extends from medulla oblongata L2 vertebra • newborns: extends to L3 or L4 • elongation of spinal cord stops ~age 3-4 but growth of vertebral column continues Spinal Cord: External View • 2 obvious enlargements noted: – cervical enlargement • C4 – T1 • serve upper limbs – lumbar enlargement • T9- T12 • serve lower limbs Spinal Cord: External View • conus medullaris: tapered conical structure of spinal cord below lumbar enlargement ending @ L1 – L2 • filum terminale: extension of pia mater extends inferiorly & anchors cord to coccyx • cauda equinae: “horse tail” nerves that arise from lumbar, sacral, & coccygeal portions of spine Spinal Nerves • 31 pairs spinal nerves emerge thru intervertebral foramen • 8 pair cervical nerves: C1 – C8 • 12 pair thoracic nerves: T1 - T12 • 5 pair lumbar nerves: L1 – L5 • 5 pair sacral nerves: S1 – S5 • 1 pair coccygeal nerves: Co1 Spinal Nerves • 2 bundles of axons, called roots, connect each spinal nerve to segment of spinal cord Spinal Cord Roots 1. posterior (dorsal) root – only sensory axons – each has dorsal root ganglion containing cell bodies of sensory neurons 2. anterior (ventral) root – only motor axons Internal Anatomy of Spinal Cord • 2 grooves penetrate white matter & divide it in right & left sides: 1. anterior median fissure 1. deeper, wider of the 2 2. posterior median sulcus 1. shallower, narrow furrow Spinal Nerves • & the nerves that branch off them are part of PNS • emerge from vertebral column thru intervertebral foramina Spinal Nerves • typically has 2 connections to spinal cord 1. dorsal root (sensory) 2. ventral root (motor) • classified as “mixed” Distribution of Spinal Nerves Spinal Nerve Plexuses • a network of nerves (or veins, or lymphatic vessels) Cervical Plexus • supplies skin & muscles of the head, neck, & superior portion of shoulders, chest, & diaphragm • C1 – C 5 Brachial Plexus • supplies the shoulders & upper limbs Lumbar Plexus • supplies anterolateral abd wall, external genitals, part of lower limb Sacral Plexus • supplies buttocks, perineum, & lower limbs Dermatomes • cutaneous area developed from one embryonic spinal cord segment & receiving most of its sensory innervation from one spinal nerve • knowing which spinal cord segments supply each dermatome makes it possible to locate damaged regions of the spinal cord Spinal Cord Injuries • most due to trauma – cervical, lower thoracic, upper lumbar most common regions involved • paralysis – depends on location, extent of damage – monoplegia: 1 limb – paraplegia: both lower limbs – hemiplegia: upper limb, trunk, lower limb on 1 side of body – quadriplegia: all 4 limbs & trunk Extent Muscle Paralysis • C1 – C3: no function neck down, requires ventilator to breathe • C4 – C5: diaphragm, allows breathing • C6 – C7: some arm, chest, allows breathing, moving wheelchair • T1 – T3: intact arm function • T4 – T9: control of trunk above umbilicus • T10 – L1: most thigh muscles, walk w/long leg braces • L1 – L2: most leg muscles, walk w/short leg braces Shingles • acute infection of PNS • caused by herpes zoster (chicken pox) • virus stays in posterior root ganglion – becomes reactivated normally immune system will prevent it from spreading – reactivated virus can overcome weakened immune system leaves ganglion travels down sensory neurons supplying skin Medical Terminology • meningitis: inflammation of meminges due to infection, bacterial (worse) or viral, vaccine protests against some bacterial causes: headache, N/V, fever, stiff neck • neuralgia: pain along a sensory nerve, trigeminal neuralgia • neuritis: inflammation of 1 or several nerves • paresthesis: abnormal sensation