School of Health Professions Department of Nutrition Sciences COURSE NUMBER and TITLE: NTR 330 Nutrition and Metabolism COURSE DESCRIPTION: This course introduces how nutrients contribute to physiological metabolism after ingesting a mixed meal. The course will cover topics including the biosynthesis of essential vitamins and co-factors and their whole food sources, the human requirements for energy, amino acids, minerals, and vitamins. These topics will be discusses in the context of food ways, including the consumption of low-carbohydrate, Western, USDA MyPlate.gov, and Mediterranean (low-animal fat) diets. Additional topics include the fortification of food, current human nutritional challenges, protective nutritional and detoxifying mechanisms and their link to complex diseases such as cardiovascular disease, Type 2 Diabetes, and obesity. SEMESTER(s) OFFERED: Summer LOCATION: Online CONTACT HOURS: 39 CREDIT HOURS: 3 hours COURSEMASTER: Name: Douglas R. Moellering, PhD Title: Assistant Professor, UAB Nutrition Sciences Office: Volker Hall (VH) G046A Phone: 205.996.2660 Email: dmoellering@uab.edu VIRTUAL OFFICE HOURS: Faculty office hours are generally Wednesdays 9:00 to 11:00 a.m. or by appointment; replies to student correspondences for consultations and course assignments will be within 24-48 hours. Appointments (in person or virtual format) to discuss course assignments or other issues should be scheduled at least 24-48 hours in advance of your desired appointment time. All Emails for correspondences should be sent to dmoellering@uab.edu. Weekend correspondences will be responded to by Monday at 12 noon. Virtual office hours will be accomplished by collaborative (web conferencing within Canvas), Skype, Email, or phone. INSTRUCTIONAL METHODS: Online Instruction via Canvas; PowerPoint presentations; Audio/Video Lectures, Electronic Readings, Group Discussion Boards (chat room), application exercises, online quizzes & exams, and Multimedia Presentations. MINIMAL TECHNICAL REQUIREMENTS: Skills the student will need to have in order to be successful in an online course include: Use a keyboard and mouse Save, open, and edit various file types Open, send, and reply to email Attach/Upload and download files Click on and open hyperlinks Navigate the Internet Navigate the Blackboard Learn course environment Download and utilize software and/or plug-ins as specified by Dr. Moellering Use and navigate audio/video peripherals within your computer or mobile device such as a webcam, microphone and speakers TECHNOLOGY REQUIREMENTS: Minimal hardware, software, plug-ins, and Internet speed needed for the course: Hardware – Headset*(optional), Microphone *(optional), Speakers, Webcam *(optional), Computer or Mobile Device Software –Adobe Acrobat Reader, Microsoft Office Plug-ins – Java, Adobe Flash Player, Adobe Acrobat Reader Internet Connection – 1 Mbps Broadband Speed (minimum) PREREQUISITES: NTR 222 Nutrition and Health REQUIRED TEXT: Smolin, LA, and Grosvenor MB. (2013) Nutrition: Science and Applications, 3rd ed. Camp Hill, PA: Wiley, John & Sons, Inc. Hardbound: ISBN-13: 978-1-1182-8826-9 ($187.95) or E-book: ISBN-13: 978-1-1185-4960-5 ($69.50); https://store.vitalsource.com/show/9781118549605; NOTE electronic device specific download required for E-book. REQUIRED MATERIALS: The following scientific publications will be required as part of the course: 1. W. Pogozelski, N. Arpaia, S. Priore. The Metabolic Effects of Lowcarbohydrate Diets and Incorporation into a Biochemistry Course. Biochemistry and Molecular biology Education 33(2):91-100, 2005 2. L. Cordain, et. al. Origins and evolution of the Western diet: health implications for the 21st century. Am J Clin Nutr 2005;81:341–54. 3. Helmut Schröder, Protective mechanisms of the Mediterranean diet in obesity and type 2 diabetes. The Journal of Nutritional Biochemistry 18(3):149–160, 2007 RECOMMENDED MATERIALS: Please see partial reading list at the end of the syllabus. COURSE OBJECTIVES: Upon completion of this course, students will be able to: ∞ Explain basic macro & micro-nutritional requirements for good health ∞ Describe basic metabolism of carbohydrates, proteins, and lipids ∞ Compare and contrast low-carbohydrate Mediterranean diets and health outcomes vs. Western vs. ∞ Integrate nutritional daily intake with energy requirements at rest and during exercise along with hydration status ∞ Discuss the detoxifying and protective mechanisms supported or challenged by individual meal choices or snacks and their links to cardiovascular disease, Type 2 Diabetes, or Obesity COURSE EVALUATION: Attendance/Online Discussions Assignments Quizzes (7 – 5% each) Mid-Term Exam Final Exam % of Grade 10 15 35 20 20 GRADING SCALE: Percentage 90-100 80-89 70-79 60-69 <59 Letter Grade A B C D F LIST OF ASSIGNMENTS: Week 1: Keep a food & drink record for 3 days during the week and calculate calories Week 3: Analysis & ranking of food record for glycemic index and glycemic load Week 6: Micronutrient analysis of food record, noting possible deficiencies and alternative sources POLICIES: 1. Review of assignments and student participation are expected. Students are responsible for completing course assignments and for participating on the Canvas course site. 2. Course assignments must be submitted for grading through the course site as directed. All assignments must be submitted by 11:00 p.m. Central Standard Time (CST) on the scheduled date posted in the syllabus to receive full credit earned. Late assignments will not be accepted without an approved excuse from the instructor. 3. Graded assignments, exams, and other materials will not be returned to the student. Grades assigned will be posted on the Canvas course site. Students may view completed quizzes in the faculty office by appointment. 4. Quizzes and examinations will be administered through the course site. Alternate test options are permitted only with prior approval from the course instructor. Make-up exams are all essay with an appropriate excused absence and notifying Dr. Moellering before or within 24 hours of missing the exam. 5. Students are responsible for maintaining current virus scan software. Files should be scanned before uploaded onto the course site or sent as e-mail attachments. Files containing a virus will be deleted to protect the integrity of the system. No credit will be given for assignments that cannot be evaluated due to the presence of a virus. GENERAL: Cell Phone/Pager Policy: All cell phones or other electronic devices should be turned off or muted during in class or online discussions. ATTENDANCE: The University regards certain absences as excused and in those instances the student is required to provide a verifiable document and prior notification and approval for known absences or missed assignments. For the student who misses assignments, presentations, examinations, or other academic work of a substantive nature by virtue of these examples of excused absences: Absences due to jury or military duty provided that official documentation has been provided to Dr. Moellering in a timely manner in advance. Absences of students registered with Disabilities Services for disabilities eligible for "a reasonable number of disability-related absences" provided students give Dr. Moellering notice of a disabilityrelated absence in advance or as soon as possible AND contact Disability Support Services (below) to register and discuss accommodations . Absences due to participation in university-sponsored activities when the student is representing the university in an official capacity and as a critical participant, provided that the procedures below have been followed: o Before the end of the add/drop period, students must provide their instructor a schedule of anticipated excused absences in or with a letter explaining the nature of the expected absences from the director of the unit or department sponsoring the activity. o If a change in the schedule occurs, students are responsible for providing Dr. Moellering with advance written notification from the sponsoring unit or department. A copy of the UAB policy on attendance can be found: http://catalog.uab.edu/undergraduate/academicstudentresources/progresstowardadegree/#enrollme nttext ACADEMIC MISCONDUCT POLICY: SHP expects students to maintain an acceptable quality of academic performance and to exhibit appropriate conduct. Students are expected to conduct themselves in a manner similar to accepted standards for practicing health care professionals. Academic misconduct may include, but is not necessarily limited to, acts such as plagiarism, cheating, misrepresentation, fabrication or giving or receiving unauthorized aid in tests, examinations, or other assigned work, and will be subject to disciplinary action. Any act of dishonesty in academic work constitutes academic misconduct. Academic misconduct will result in a grade of zero on the assignment/exam and may result in disciplinary action. A student who feels he or she has been unfairly disciplined should contact the program director or department chair to request a review of the disciplinary decision. A more detailed description of the Grievance Procedures for Violations of Academic Standards is available from the Office of the Assistant Dean for Academic and Student Affairs, or at the following website: http://catalog.uab.edu/undergraduate/academicstudentresources/progresstowardadegree/#conductcomp laintstext NON-ACADEMIC MISCONDUCT POLICY: “The University is a community of scholars and learners; therefore, all participants are expected to maintain conduct which (1) facilitates the institution's pursuit of its educational objectives, (2) exhibits a regard for the rights of other members of the academic community, and (3) provides safety to property and persons. Through appropriate due process procedures, disciplinary action will be taken in response to conduct that violates these principles. A more detailed description of non-academic misconduct can be found in the UAB student handbook, Direction. It is the student's responsibility to be fully aware of the policies and procedures described in this document, which may be obtained from the SHRP Office of the Associate Dean for Academic and Student Affairs (SHP Building, Room 660) Several UAB-wide policies apply to students. The following policies or policy summaries are included on the UAB Policies page of the catalog. Students are expected to comply with the UAB DIRECTION Student Handbook. Additional information on Non-Academic Conduct can be found at the following website: http://www.uab.edu/handbook/f-policies-procedures/studentconduct/b-iv-non-acadcode TURNITIN POLICY: Plagiarism is academic misconduct that will result in a grade of zero on the plagiarized assignment and may result in dismissal from the School of Health Professions and the University (see DIRECTION or SHP Grievance Procedures for Violations of Academic Standards). All papers submitted for this course may be reviewed using the online plagiarism monitoring software, Turnitin.com. Also, please note that all documents submitted to Turnitin.com are added to their database of papers that is used to screen future assignments for plagiarism. Some of your assignments may need to be submitted using Turnitin and information about the process of submitting work to this system may be found at the following website: http://www.uab.edu/bblearn/using-turnitin DISABILITY SUPPORT SERVICES: How to Register for DSS Support Services Contact DSS at (205) 934-4205 (voice) or (205) 934-4248 (TDD), or visit 516 Hill University Center. You must present documentation of disability to receive DSS services. After DSS receives your completed documentation, you will meet individually with a member of the staff to discuss your accommodations. It’s best to register with DSS when you apply to UAB. For more information about Disability Services, please feel free to contact the office directly or visit their website for more information. Disability Support Services 9th Ave. Office Building 1701 9th Ave. South Birmingham, AL 35294-1150 (205) 934-4205 (Voice) (205) 934-4248 (TDD) Fax: (205) 934-8170 Email: dss@uab.edu Students who may need course accommodations should make an appointment with Dr. Moellering to discuss their needs. Students with disabilities must be registered with Disability Support Services (DSS) and provide an accommodation request letter before receiving academic adjustments. Appointments or additional information is available on the UAB website at: https://www.uab.edu/students/services/disability-support-services COURSE OUTLINE AND CALENDAR Week Week 1 June 23-29 Module 1: Learning Units 1-2 Week 2 June 30- Topic Overview of Basic Concepts in Nutrition and Metabolism Cellular and Molecular Aspects of Nutrition - Macronutrients Comparisons Low-Carbohydrate vs. Western vs. Mediterranean Diet; Overview Metabolism; Standard Metabolic Rate, Energy Pathways; Assignment/Quiz Quiz 1-syllabus; Food record 3 days with calculated calories Quiz 2 July 6 Module 2: Learning Units 3-4 Week 3 July 7-13 Module 3: Learning Units 5-6 Acetyl-CoA Mono-, Di-, Oligo-, Poly-saccharides and functions, RCTs or other clinical data and 3 Comparison Diets Carbohydrates & Metabolism Glycemic Index and Glycemic Load Week 4 July 14-20 Week 5 July 21-27 Module 4: Learning Units 7-9 Week 6 July 28-Aug 3 Module 5: Learning Units 10-13 Quiz 4; Analysis & ranking of food record for glycemic index and glycemic load Mid-Term Examination Protein, Lipids & Metabolism Hydration & Metabolism Energy, Fuel Utilization-Rest & Exercise Micronutrients - B vitamins Quiz 5 Micronutrients - C, E, K, A Week 7 Aug 4-8 Quiz 3 Micronutrients - minerals Detoxifying & Protective Mechanisms of nutrition and their link to Cardiovascular Disease, Type 2 Diabetes Mellitus, and Obesity Final Exam Micronutrient analysis of food record, noting possible deficiencies and alternative sources Quiz 6 Quiz 7 GRADING RUBRIC Criteria Clearly written with correct grammar and spelling Excellent (5 points) Satisfactory (4 points) Needs improvement (3 points) Unacceptable (2 points) Thoughtful Refers to the course material and its concepts Reflects upon what interested him/her about the community organization and subject matter Reflects upon how he/she might use ideas from the course for application to this community setting Reflects upon personal selfawareness and interactions Partial Reading List: The following readings will be required for the class. Other readings may be assigned throughout the semester. The instructor will provide PDF’s or links to assigned readings on Blackboard Learn. L. E. Spieth, J. D. Harnish, C. M. Lenders, L. B. Baezer, M. A. Pereira, S. Jan Hangen, D. S. Ludwig (2000) A low-glycemic index diet in the treatment of pediatric obesity, Arch. Pediatr. Adolescent Med. 154, 947–959. J. M. Bachman (2001) The low-carbohydrate diet in primary care OB/GYN, Prim. Care Update Obstet. Gyn. 8, 12–17. E. C. Westman, J. Mavropoulos, W. S. Yancy, Jr., J. S. Volek (2003) A review of low-carbohydrate ketogenic diets, Curr. Atheroscler. Rep. 5, 476–483. W. S. Yancy, Jr., J. R. Guyton, R. P. Baskst, E. C. Westman (2002) A randomized, controlled trial of a lowcarbohydrate, ketogenic diet vs. a low-fat diet for obesity and hyperlipidemia, Am. J. Clin. Nutr. 72, 343S. G. D. Foster, H. R. Wyatt, J. O. Hill, B. G. McGuckin, C. Brill, B. S. Mohammed, P. O. Szapary, D. J. Rader, J. S. Edman, S. Klein (2003) A randomized trial of a low-carbohydrate diet for obesity, N. Engl. J. Med., 358, 2082–2090.