Severe Acute Respiratory
Syndrome
Hannah Burris
Karen He
Heather Min
http://news.bbc.co.uk/nol/shared/spl/hi/health/03/travel_health/diseases/img/sars.jpg
What is SARS?
• It is a severe viral
pneumonia.
• It is caused by a
coronavirus
(SARS-CoV).
• Over the 2003
outbreak, 8,098
people were
infected by SARS
and 774 people
died from it.
http://www.wadsworth.org/images/virology/SARS.jpg
The Emergence of SARS
• First emerged at Guangdong in
November 2002.
• SARS was formed from many
agents.
• Reached Hong Kong in
February 2003.
• By February 11, 2003, China
had three-hundred cases and
five deaths from SARS.
-Became a global threat by
March 2003.
http://nabc.ksu.edu/images/uploads/sars.jpg
Properties of the SARS-CoV
• Incubation period=two
to seven days
• Chance of transmission
is greatest around the
tenth day.
• Began with bats.
– SARS jumped to
humans by the Civet
cats
http://msnbcmedia4.msn.com/j/msnbc/Components/Photos/2006/April/060417/060418_civet_vmed_9a.widec.jpg
How SARS Spreads
•
•
•
•
Person to person contact
Bodily fluids
Respiratory droplets
Touching things that were already contaminated
http://www.sachsreport.com/SARS%2520may%2520be%2520spread%2520by%2520sweat.jpg
Symptoms
•
•
•
•
•
•
•
•
http://www.nti.org/images/e3_84_01.jpg
High fever
Headache
Myalgia
Dry cough
Chills
Fatigue
Dizziness
Pneumonia
Diagnosis
• Doctor Questionnaire
– Travel
– Workplace
– Direct contact with
infected individuals
• Chest x-rays: used to
find atypical
pneumonia or
respiratory distress
syndrome
http://www.brown.edu/Courses/Bio_160/Projects2004/sars/chestxray.gif
Super-Spreader Events
• Metropole Hotel
• Prince of Wales Hospital
• Amoy Gardens Apartment Complex
http://images.our-hotels.com/countries/hong-kong/kowloon/hotels/metropark/metropark-hotel-m.jpg
http://ihome.cuhk.edu.hk/~b113406/images/PWH.jpg
http://newsimg.bbc.co.uk/media/images/39031000/jpg/_39031645_amy-cred203.jpg
Time
Time
D
ec
e
m
r
be
r
be
t
gu
s
ly
Tim e
pt
em
Au
Ju
ne
Hong Kong
Ju
ay
M
2000
1800
1600
1400
1200
1000
800
600
400
200
0
ril
D
be
r
m
t
r
gu
s
pt
em
be
ec
e
Se
Au
ly
ne
Ju
Ju
ay
M
ril
ch
Ap
0
Ap
50
Cumulative Number of SARS
Cases
100
M
ar
be
r
m
r
150
ch
ec
e
be
t
200
ar
D
pt
em
gu
s
250
Cumulative Number of SARS
Cases
be
r
m
r
Se
ly
300
M
ec
e
pt
em
be
t
gu
s
Au
ne
Ju
Ju
ril
ay
M
Ap
ch
ar
M
Cumulative Number of SARS
Cases
Canada
Se
D
Se
Au
ly
ne
Ju
Ju
ril
ay
M
Ap
ch
ar
M
Cumulative Number of SARS
Cases
Cumulative Numbers of SARS Cases in Canada,
China, Hong Kong, and Taiwan
China
6000
5000
4000
3000
2000
1000
0
Time
Taiwan
800
700
600
500
400
300
200
100
0
Time
Au
Time
gu
s
ly
ne
ay
Time
Ju
Ju
M
il
ch
Ap
r
70
60
50
40
30
20
10
0
Cumulative Number of SARS
Cases
Vietnam
ar
be
r
m
r
t
r
ay
Ju
ly
ne
M
il
Ap
r
Ju
Cumulative Number of SARS
Cases
ch
ar
Au
t
be
r
m
M
ec
e
be
pt
em
gu
s
gu
st
Se
pt
em
be
r
D
ec
em
be
r
D
Se
Au
16
14
12
10
8
6
4
2
0
M
ec
e
be
pt
em
gu
s
ly
ne
ay
ril
Ju
Ju
M
Ap
ch
ar
M
Cumulative Number of SARS
Cases
Philippines
t
Se
pt
em
be
r
D
ec
em
be
r
D
Se
Au
ly
ne
Ju
Ju
ay
M
ril
ch
ar
Ap
M
Cumulative Number of SARS
Cases
Cumulative Numbers of SARS Cases in the Philippines,
Singapore, Vietnam, and the United States
Singapore
250
200
150
100
50
0
Time
United States
250
200
150
100
50
0
Cumulative Numbers of SARS Cases and Deaths
Worldwide
9000
8000
7000
6000
5000
4000
3000
2000
1000
0
Time
9000
8000
7000
6000
5000
4000
3000
2000
1000
0
M
1000
900
800
700
600
500
400
300
200
100
0
Cases
Deaths
ch
ar
A
il
pr
M
ay
ne
Ju
ly
Ju
st
er
er
u
b
b
m
m
ug
te
A
ce
p
e
e
D
S
Time
t
Se
pt
em
be
r
D
ec
em
be
r
Au
gu
s
ly
Ju
ne
Ju
ay
M
ril
Ap
ch
Time
M
ar
Cumulative Number of Deaths
Caused by SARS
World: Deaths
Cumulative Number of
Cases/Deaths
be
r
De
ce
m
be
r
Se
pt
em
Au
gu
st
Ju
ly
Ju
ne
ay
M
M
Ap
ril
World: Cases and Deaths
ar
ch
Cumulative Number of
Cases
World: Cases
Based on the data from December 2003,
about 9.6% of SARS cases result in death.
Treatment
http://cache.viewimages.com/xc/1951127.jpg?v=1&c=ViewImages&k=2&d=17A4AD9FDB9CF1939057D9939C83F1063C373E1278816F435A5397277B4DC33E
• No specific cure available
– A combination of steroids and interferons
– Oral ribavirin
Board Game
References
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CDC: - Severe Acute Respiratory Syndrome (SARS)
 http://www.cdc.gov/ncidod/sars/index.htm
China: WHO: Full Recovery of SARS Averages 85 Percent
 http://www.china.org.cn/english/features/sars/67356.htm
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 http://www.medicalnewstoday.com/articles/5015.php
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 http://www.nlm.nih.gov/medlineplus/severeacuterespiratorysyndrome.html
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 http://www.who.int/csr/sars/country/en/index.html
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 http://virology-online.com/viruses/sars.htm