Elizabeth Bell
Julene Clarke
Sierra Perez
Nicole Williams
HSC 440
Evaluation Techniques
Goal: Provide accurate and helpful information to the parents of children that are affected by
blood disorders.
Unit I: Anemia
Unit Objective: By the end of the unit, the parents will be able to interpret their child’s
condition of anemia.
Instructional Objectives (Enabling Objectives): By the end of the lesson, the parents will be
able to:
1.1 Know what the definition of anemia.
1.2 List the symptoms of anemia.
1.3 Interpret the diagnosis of anemia.
1.4 Identify risk factors of anemia.
1.5 Identify two complications of anemia.
1.6 List two methods to treat anemia.
1.7 Identify three foods that are good for anemic children.
1.8 List three foods that affect the body’s consumption of iron.
Unit II: Sickle Cell Disease
Unit Objective: By the end of the unit the parents will be able to interpret their child’s sickle
cell disease (SCD).
Instructional Objectives: By the end of the lesson, the parents will be able to:
2.1 Interpret the different types of SCD.
2.2 List why SCD is problematic.
2.3 Identify three symptoms of SCD.
2.4 Determine how SCD is tested.
2.5 Determine what treatments are available for SCD.
Unit III: von Willebrand Disease
Unit Objective: By the end of the unit, the parents will be able to interpret the diagnosis of
von Willebrand disease (vWD).
Instructional Objectives (Enabling Objectives): By the end of the lesson, the parents will be
able to:
3.1 Define vWD.
3.2 Identify two possible complications of vWD.
3.3 Interpret the von Willebrand factor (i.e. factor VIII).
3.4 Distinguish between the three major types of vWD (Types 1, 2, and 3).
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3.5 Prepare medical history to report to the doctor.
3.6 Appraise diagnostic tests.
3.7 Critique the different treatment options.
3.8 Select the best treatment option for your individual case.
Unit IV: Leukemia
Unit Objective: By the end of the unit the parents will be able to identify how to care for the
child with leukemia.
Instructional Objectives (Enabling Objectives): By the end of the lesson, the parents will be
able to:
4.1 Define leukemia.
4.2 Determine the main types of leukemia.
4.3 Explain the causes of leukemia.
4.4 Explain the symptoms of leukemia.
4.5 Assess leukemia treatments.
4.6 Assess what happens after leukemia treatment.
Unit V: Hemophilia
Unit Objective: By the end of the unit, the parents will be able to analyze the blood disorder
Hemophilia.
Instructional Objectives (Enabling Objectives): By the end of the lesson, the parents will be
able to:
5.1 Define hemophilia.
5.2 Determine how hemophilia is “inherited”.
5.3 Describe what platelets are.
5.4 Schedule physical exams and blood tests.
5.5 Compare the two types of hemophilia (Types A or B).
5.6 Distinguish the difference between the severities of hemophilia.
5.7 Plan for a pregnant woman (that is a carrier) to be diagnosed as early as 12 weeks
into pregnancy.
5.8 Assess a “preimplantation diagnosis”.
5.9 Critique the different treatment options.
5.10 Select the best form of treatment for you.
5.11 Assess immunization options for children that have hemophilia.
Unit VI: Alpha Thalassemia
Unit Objective: By the end of the unit, the parents will be able to comprehend the blood
disorder alpha thalassemia.
Instructional Objectives (Enabling Objectives): By the end of the lesson, the parents will be
able to:
6.1 Define thalassemia.
6.2 Define alpha thalassemia.
6.3 Select 5 symptoms of alpha thalassemia in children.
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6.4 List 5 complications of alpha thalassemia in children.
6.5 Differentiate among the various forms of alpha thalassemia.
6.6 Interpret how alpha thalassemia is diagnosed.
6.7 Recall the types of treatment for alpha thalassemia.
MULTIPLE CHOICE: Please select the best answer for each question.
1. (6.1) Thalassemia is a blood disorder that:
A.
B.
C.
D.
Is an inherited.
Is a disorder that affects the way the body makes hemoglobin.
Causes RBCs to be destroyed at a faster rate.
All of the above
2. (6.2) What is alpha thalassemia?
A. Alpha thalassemia is when the body has a problem producing alpha globin.
B. Alpha thalassemia is when the body is missing the four genes that make alpha
globin protein chains.
C. Both A and B.
D. None of the above.
3. (6.3) Select the symptoms of alpha thalassemia in children.
A.
B.
C.
D.
E.
Anemia
Fatigue, weakness, or shortness of breath
Pale appearance or jaundice
Swollen abdomen
All of the above
4. (6.4) Select the possible complication of alpha thalassemia in children.
A.
B.
C.
D.
E.
Slower growth rates
Infections
Enlarged spleen
Excess iron
All of the above
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5. (6.5) Which of the following is NOT a form of alpha thalassemia?
A.
B.
C.
D.
E.
Alpha thalassemia silent carrier
Alpha thalassemia major (hydrops fetalis)
Alpha thalassemia minor (alpha thalassemia trait)
Alpha thalassemia medious (alpha thalassemia transitional)
Hemoglobin H disease
6. (6.6) Which of the following is NOT a used to diagnose alpha thalassemia?
A.
B.
C.
D.
Urine test
Chorionic vilius sampling
Amniocentesis
Blood tests
7. (6.7) Which of the following is NOT a treatment for alpha thalassemia?
A.
B.
C.
D.
Blood transfusions
Bone marrow transplant
Iron chelation therapy
Folic acid supplements
8. (1.1) Anemia is a condition in which your blood has a lower than normal number of red
blood cells.
A. True
B. False
9. (1.3) Anemia can be diagnosed by: medical and family history a physical exam a blood
test.
A. True
B. False
10. (1.4) All of the following are risk factors of anemia except
A.
B.
C.
D.
E.
A diet that is low in iron
Blood loss from surgery
Communicable illness
Long-term infections
Family history of inherited anemia
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11. (1.5) What are the two complications of Anemia?
A.
B.
C.
D.
Headache and ringing in the ears
Mood swings and pale skin
Impair growth and short attention span
Increased alertness and common cold
12. (1.7) Food that are good source of iron for anemic children are:
A.
B.
C.
D.
E.
Liver
Fortified cereals
Spinach
Eggs
All of the above
13. (1.8) Foods that affect the body’s consumption of iron:
A.
B.
C.
D.
E.
Fish
Antacids
Milk
Both b and c
None of the above
14. (1.6) List two common methods to treat anemia:
A. _________________
B. _________________
15. (1.2) List four common symptoms of anemia:
A.
B.
C.
D.
E.
_________________
_________________
_________________
_________________
_________________
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(2.1) Match the types of SCD, common and rare.
16. HbSS ____________
17. HbSE ____________
18. HbSD ____________
19. HbSS ____________
20. HbSC ____________
21. HbSO ____________
22. (2.2) List the reasons why SCD is problematic.
A.
B.
C.
D.
E.
_________________
_________________
_________________
_________________
_________________
23. (2.3) SCD Symptoms are:
A.
B.
C.
D.
E.
Chest pain
Stomach pain
Fatigue and Shortness of breath
Bone Pain
All of the above
24. How is SCD tested?
A.
B.
C.
D.
E.
A blood test
Family history
Blood oxygen saturation
Complete blood count (CBC)
All of the above
25. (2.5) All of the treatments are used of SCD, except for
A.
B.
C.
D.
Blood transfusions
Folic acid Supplements
Pain medicines
Plenty of fluids
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26. (3.1) Von Willebrand Disease
A.
B.
C.
D.
E.
Is a disease of the Willebrand factor
Is a man with a disease
Has nothing to do with blood
Can kill you
Both A and D
27. (3.2) Von Willebrand Disease
A.
B.
C.
D.
E.
Can mean your Willebrand factor is missing
Can mean your blood is too thick
Can mean your blood is missing
Can mean your Willebrand factor is damaged
Both A and D
28. (3.3) The Von Willebrand factor is involved in homeostasis and causes von Willebrand
Disease
A. True
B. False
29. (3.7) For women it is bad to use contraceptives to help treat this blood disorder
A. True
B. False
Fill in the blank
30. (3.4) People who have ____________ have low levels of von Willebrand factor
31. (3.4) People who have ____________ the Willebrand factor doesn’t work well
32. (3.4) People who have ____________ there is no Willebrand factor in them
33. (4.1) Leukemia is a cancer in the bone marrow and lymphatic system
A. True
B. False
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34. (4.1) Leukemia forms abnormal
A.
B.
C.
D.
White blood cells
Red blood cells
Palates
None of the above
35. (4.4) Swollen lymph nodes are not a symptom of leukemia
A. True
B. False
36. (4.2) The most common type of leukemia in children is
A.
B.
C.
D.
Acute lymphocytic.
Acute myelogenous
Chronic lymphocytic
Chronic myelogenous
37. (4.2) This type of leukemia mainly affects adults
A.
B.
C.
D.
Acute lymphocytic
Acute myelogenous
Chronic lymphocytic
Chronic myelogenous
38. (4.5) Which of these is NOT a treatment for Leukemia
A.
B.
C.
D.
E.
Medication
Meditation
Chemotherapy
Radiation therapy
Transplant
Fill in the blank
39. (4.3) Leukemia can be caused by both ________ factors and _______ factors.
40. (4.2) _________ leukemia occurs over time and almost never affects children.
41. (4.2) _________ leukemia occurs suddenly and mostly occurs in adults.
42. (5.1) A rare bleeding disorder that occurs when the blood doesn’t clot normally is
called ____________
43. (5.3) ____________ are small blood fragments that form in the bone marrow
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(5.4) Match the Blood Test to its description
44. Prolonged Partial Thromboplastin
Time (APTT)
45. Normal Prothrombin Time (PT)
46. Platelet Count
47. Bleeding Time
48. Reduced factor VIII activity
49. Factor VIII mutation analysis
A. Tests how long it takes for a blood
to clot.
B. Tests how long it takes for the
plasma portion of your blood to
clot.
C. Tests the small blood vessels in
your skin to see how fast they close
to stop the bleeding.
D. A test that counts the amount of
platelets in your blood.
E. This test consists of a gene
sequencing; taking a look at the
affected/mutated factor VIII gene.
F. This test measures the activity level
of the factor VII
Fill in the blank.
50. (5.5)_________Considered to be missing or have low levels of factor VIII.
51. (5.5)_________Considered to be missing or have low levels of factor IX.
52. (5.7) Women who are carriers for the ___________gene can be tested at the 12-week
mark.
53. (5.8)______________is a procedure that takes the sperm from the dad and the egg from
the mom; then fertilize in a lab where the embryos are tested for hemophilia
54. (5.2) Is Hemophilia “inherited” form a parent through an abnormal gene?
A. True
B. False
55. (5.9) Involves a concentration of vWF and factor VIII that is administered into your arm
via a vein
A.
B.
C.
D.
E.
Replacement Therapy
Desmopressin
Antifibrinolytic Medicines
Gene Therapy
Treatment of Specific Bleeding Sites
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56. (5.9) Is a man- made hormone that treats people with mild cases of hemophilia
A.
B.
C.
D.
E.
Replacement Therapy
Desmopressin
Antifibrinolytic Medicines
Gene Therapy
Treatment of Specific Bleeding Sites
57. (5.9) Aminocaproic acid or tranexamic acid.
A.
B.
C.
D.
E.
Replacement Therapy
Desmopressin
Antifibrinolytic Medicines
Gene Therapy
Treatment of Specific Bleeding Sites
58. (5.9) Not an accepted treatment option, it is still in the research stages, but is being used
in clinical trials.
A.
B.
C.
D.
E.
Replacement Therapy
Desmopressin
Antifibrinolytic Medicines
Gene Therapy
Treatment of Specific Bleeding Sites
59. (5.9) Pain medicines, steroids, and physical therapy can all be used to reduce pain in
affected joints
A.
B.
C.
D.
E.
Replacement Therapy
Desmopressin
Antifibrinolytic Medicines
Gene Therapy
Treatment of Specific Bleeding Sites
60. (5.10) Desmopressin is given to raise the body’s factor VIII hormone levels
A. Mild hemophilia
B. Moderate hemophilia
C. Severe hemophilia
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61. (5.10) Replacement therapy will be needed only when bleeding is present or there is a
possibility that bleeding will occur (physical activities
A. Mild hemophilia
B. Moderate hemophilia
C. Severe hemophilia
62. (5.10) Need replacement therapy to prevent bleeding in the joints, muscles, or other parts
of the body. (Started in patients at a young age and most likely lasts through their entire
life).
A. Mild hemophilia
B. Moderate hemophilia
C. Severe hemophilia
Essay Question
63. (5.11) What are immunizations options for children with hemophilia?
64. (5.6) Compare the differences between the severities of hemophilia.
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65. (4.6) Describe the problems that can happen after treatment for leukemia
66. (3.8) Compare the treatment options for Type 1, 2, 3 vWD.
67. (3.6) Describe what medical history and observations should be reported to a doctor when
your child has vWD.
68. (3.5) Compare and contrast between the three major types of vWD.
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