Topic 2: cells

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TOPIC 1: CELL BIOLOGY
1.6 Cell division
1 - INTERPHASE
Read & Consider 1.6.4-1.6.5
• What do you know?
• What questions do you have?
• Based on the graphic above, how much
of a cell’s life is spent in interphase?
INTERPHASE
INTERPHASE
The cell carries out specialized functions as well as
several metabolic reactions. It consists of three
phases: Gap 1 (G1), Synthesis (S), and Gap 2 (G2).

Interphase Activities:
Active cytoplasm of a growing cell
 New organelles formed (mitochondria,
chloroplasts, etc.
 Enzymes produced for S phase
 DNA is copied
 Increase in histone production.
 Increase in microtubule production.

CYCLINS – CONTROLLING THE CELL CYCLE
Cyclins are
proteins
that interact
with CDKs
(cyclindependent
kinase) to
form
enzymes
that control
cell cycle.
2 - MITOSIS
Read & Consider 1.6.1-1.6.3
• What do you know?
• What questions do you have?
• What is the result of mitosis?
DNA TERMINOLOGY
Chromosome/Chromatid – single DNA molecule
 Sister chromatid – two identical DNA molecules
attached by a centromere


This attachment helps to organize genetic material
within the cell.
ORGANIZING
DNA
MITOSIS & CYTOKINESIS
Mitosis: division of the nucleus followed by
cytokinesis, the division of the cytoplasm.
1. Describe, in detail,
the events of each
phase of mitosis.
2. Draw a labeled
diagram of each
phase.
Hoover.k12.al.us
PROPHASE
METAPHASE
ANAPHASE
TELOPHASE
CYTOKINESIS
In a plant cell.
DNA
Draw a graph to indicate the amount of
DNA in a cell over time.
Time
CELL CYCLE STAGE IDENTIFICATION
ONION ROOT – MITOTIC INDEX
You will classify each cell
based on what phase it is
in. At the end you will
count up the cells found in
each phase and use those
numbers to determine the
mitotic index = % of cells
found in mitosis.
3 - CANCER
Read & Consider 1.6.6
• What do you know?
• What questions do you have?
• How has your life been impacted by
cancer?
TUMORS
 Primary
Tumor –
tumor found in the
original tissue.
 Secondary Tumor –
tumor that has
migrated to other
tissues via
metastasis.
Cancer Behavior
Breast cancer tumor – hyscience.com
CAUSES
 They
can occur in any tissue. Triggered
by:
Mutagens
 Oncogenes

SMOKING & CANCER
WORKS CITED






"Cancer Cell Has Potential On-off Switch - Medicure
Medical Travels LLP." Medicure Medical Travels
LLP. N.p., n.d. Web. 01 Aug. 2014.
C, Cindy. "Anatomy & Physiology 2401 Kandeh
Flashcards The Stages of the Cell Cycle | StudyBlue."
StudyBlue. N.p., 14 Feb. 2013. Web. 31 July 2014.
"Mitosis." BiologyEOC -. N.p., n.d. Web. 31 July 2014.
"Onion Root Tip (Allium) Showing Cells in Various
Stages of Mitosis. LM X100." - 42-29390593. Corbis
Images, n.d. Web. 01 Aug. 2014.
Piatt. "Mitosis Phases and Cell Cycle - Chapter 8
Matching." Quia -. Chilarol Area High School, n.d.
Web. 31 July 2014.
Walpole, Benda. Biology for the IB Diploma. Second
ed. United Kingdom: Cambridge UP, 2014. Print.
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