sd41.k12.id.us TOPIC 1: CELL BIOLOGY 1.6 Cell division 1 - INTERPHASE Read & Consider 1.6.4-1.6.5 • What do you know? • What questions do you have? • Based on the graphic above, how much of a cell’s life is spent in interphase? INTERPHASE INTERPHASE The cell carries out specialized functions as well as several metabolic reactions. It consists of three phases: Gap 1 (G1), Synthesis (S), and Gap 2 (G2). Interphase Activities: Active cytoplasm of a growing cell New organelles formed (mitochondria, chloroplasts, etc. Enzymes produced for S phase DNA is copied Increase in histone production. Increase in microtubule production. CYCLINS – CONTROLLING THE CELL CYCLE Cyclins are proteins that interact with CDKs (cyclindependent kinase) to form enzymes that control cell cycle. 2 - MITOSIS Read & Consider 1.6.1-1.6.3 • What do you know? • What questions do you have? • What is the result of mitosis? DNA TERMINOLOGY Chromosome/Chromatid – single DNA molecule Sister chromatid – two identical DNA molecules attached by a centromere This attachment helps to organize genetic material within the cell. ORGANIZING DNA MITOSIS & CYTOKINESIS Mitosis: division of the nucleus followed by cytokinesis, the division of the cytoplasm. 1. Describe, in detail, the events of each phase of mitosis. 2. Draw a labeled diagram of each phase. Hoover.k12.al.us PROPHASE METAPHASE ANAPHASE TELOPHASE CYTOKINESIS In a plant cell. DNA Draw a graph to indicate the amount of DNA in a cell over time. Time CELL CYCLE STAGE IDENTIFICATION ONION ROOT – MITOTIC INDEX You will classify each cell based on what phase it is in. At the end you will count up the cells found in each phase and use those numbers to determine the mitotic index = % of cells found in mitosis. 3 - CANCER Read & Consider 1.6.6 • What do you know? • What questions do you have? • How has your life been impacted by cancer? TUMORS Primary Tumor – tumor found in the original tissue. Secondary Tumor – tumor that has migrated to other tissues via metastasis. Cancer Behavior Breast cancer tumor – hyscience.com CAUSES They can occur in any tissue. Triggered by: Mutagens Oncogenes SMOKING & CANCER WORKS CITED "Cancer Cell Has Potential On-off Switch - Medicure Medical Travels LLP." Medicure Medical Travels LLP. N.p., n.d. Web. 01 Aug. 2014. C, Cindy. "Anatomy & Physiology 2401 Kandeh Flashcards The Stages of the Cell Cycle | StudyBlue." StudyBlue. N.p., 14 Feb. 2013. Web. 31 July 2014. "Mitosis." BiologyEOC -. N.p., n.d. Web. 31 July 2014. "Onion Root Tip (Allium) Showing Cells in Various Stages of Mitosis. LM X100." - 42-29390593. Corbis Images, n.d. Web. 01 Aug. 2014. Piatt. "Mitosis Phases and Cell Cycle - Chapter 8 Matching." Quia -. Chilarol Area High School, n.d. Web. 31 July 2014. Walpole, Benda. Biology for the IB Diploma. Second ed. United Kingdom: Cambridge UP, 2014. Print.