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GENERAL CHEMISTRY

Miss Napolitano & Mrs. Haas

CP Biology

Chemistry!

• All living things are composed of matter

• Matter: anything that takes up space and has mass

• Matter is made up of elements

• Elements: substance that cannot be broken down into other substances

• A substance consisting of 2+ elements in a fixed ratio is called a compound

• Ex: NaCl, C

6

H

12

O

6

• Essential elements of life: CHNOPSCaK

(carbon, hydrogen nitrogen, oxygen, phosphorus, sulfur, calcium, potassium)

Atomic Structure

• Atoms : smallest unit of matter

• Made up of subatomic particles

• Protons: positive charge <-- in nucleus!

• Neutrons: neutral (no) charge <-- in nucleus!

• Electrons: negative charge

• Atomic number : number of protons

• Mass number : number of protons + number of neutrons

Bohr Model

• Shows nucleus (with P + and N o ) as well as energy levels with electrons

• 1 st energy level can hold 2 electrons

• 2 nd & 3 rd energy levels can hold 8 electrons each

• Electrons are paired when 4+ in a shell

Valence Shell

• Valence shell: outermost shell, contains valence electrons

• Valence electrons: electrons involved in chemical bonding

Lewis Dot Diagrams

• Shows the chemical symbol for the element with valence electrons

• Electrons are drawn in a circle around the symbols

• Electrons are paired if there are 4+ in its valence shell

Isotopes

• Isotopes: Atoms of the same element with different numbers of neutrons

• Radioactive isotopes occur when the nucleus decays and gives off particles & energy

• When protons are lost, new elements are formed

• Useful in fossil dating & PET scans

Carbon Isotopes

Chemical Bonds

• Chemical bonds: attraction between 2+ atoms

• Driving force – full valence shells

• 3 types for this class:

• Covalent bonds

• Ionic bonds

• Hydrogen bonds

Covalent Bonds

• Sharing of a pair of valence electrons to create a molecule

• Example: CH

4

• 2 types of covalent bonds:

• Nonpolar covalent: electrons are shared equally throughout the molecule

• Molecules are usually symmetrical, such as CH

4

• Polar covalent: electrons are not shared equally throughout the molecule due to differences in electronegativity

• Molecules are usually asymmetrical, such as H

2

O

Ionic Bonds

• In ionic bonding , the electronegativity is so strong in one atom that it “takes” an electron from the other

• Create either positive cations or negative anions (types of ions ), and opposite charges are attracted to one another

• Form salts such as NaCl

Hydrogen Bonds

• Hydrogen bond: weak attractions between H and O or N of different molecules

• Remember! H

2

O is an example of a polar covalent molecule, so H and O have partial positive & negative charges!

• Partial negative charge of O ( δ ) attracts partial positive charge ( δ + ) of H of a different water molecule

Chemical Reactions

• Chemical reaction (rxn): the making or breaking of chemical bonds leading to changes in matter

• Reactants: starting materials

• Products: end result

• Coefficients: the number of molecules involved

• Some reactions are reversible

• A reaction becomes stable when it reaches equilibrium

Chemical Reactions

• Endothermic reactions: absorb energy

• Exothermic reaction: release energy

Water

• 71% of Earth’s surface is water!

• Up to 60% of an adult human body is made up of water!

• Water is polar (unequal distribution of charges)

• Water molecules are held together by covalent bonds

• Water molecules are held to one another by hydrogen bonds

Properties of Water

• Cohesion: Water “sticks” to itself

• Ex: drops of water on wax paper

• Adhesion: Water “sticks” to other substances

• Ex: meniscus in a graduated cylinder

• Capillary action: moves against gravity

• Ex: water movement in plants

• Surface tension: difficult to break the surface of water

• Ex: Water strider on top of a pond

Properties of Water

• Moderate temperature

• Freezes at 0 o C, boils at 100 o C

• Body temp = 37 o C

• High specific heat – amount of heat absorbed or lost for

1g of a substance to change 1 o C

• Water: 1 cal/g/ o C due to H bonds

• Therefore, resists changes in temperature (ex: ocean)

• Evaporative cooling – prevents organisms from overheating

Properties of Water

• Expansion upon freezing

• Less dense as a solid than a liquid

Water condenses until 4 o C, then expands

Ice floats & insulates water beneath it, allowing for life to thrive

• Versatile solvent

• Solute: substance being dissolved

• Solvent: substance doing the dissolving

Solution: homogenous mixture of 2+ substances

Aqueous solution: water is the solvent

• Water forms a hydration sphere around ionic compounds and dissolves polar compounds

• Hydrophilic: mixes well with water

• Hydrophobic: repels water (nonpolar)

Hydration Spheres

Acids & Bases

• Due to the dissociation of water

• Hydrogen ion (H + ) is transferred to another molecule

Left with hydroxide ion (OH )

Process is reversible!

• Acids: increase H + concentration

• Ex: Hydrochloric acid (HCl)

• Bases: reduce H + concentration

• Ex: Sodium hydroxide (NaOH)

• Strong acids & bases dissociate completely when mixed with water

The pH Scale

• In any aqueous solution at 25 o C, [H + ][OH ] = 10 -14

• pH = -log [H + ]

• Ex: For pure water, [H + ] = 10 -7 so –log [10 -7 ] = 7 therefore pH = 7

• pH declines as H + increases

The pH Scale

Buffers

• Internal pH of most cells is about 7

• Changes in pH can be harmful to cells

• Buffers: minimize changes in concentrations of H + and

OH in a solution

• Work by accepting excess H + in acidic solutions or donating H + in basic solutions

• Most contain a weak acid & a corresponding base

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