CELLTASIA Exploring Cellular Processes Through The Arts http://biomafia-biology.blogspot.com/2008/01/cell-growth-and-division-definitions.html Robin Cook Hill, PhD Assistant Professor of Developmental Biology The University of Virginia’s College at Wise “Molecules in the cell encounter each other very frequently because of their continual random thermal movements. Colliding molecules with poorly matching surfaces form few noncovalent bonds with one another, and the two molecules dissociate as rapidly as they come together” (Alberts, Molecular Biology of the Cell, 5th edition, pg.157) Terminology Thermal movements Noncovalent bonds Dissociate Structures Molecules Surfaces Processes Colliding molecules Bond formation Rapid dissociation (Turro, 2005) Goals: 1) 2) 3) 4) Deeper understanding of course material Time to prepare for the final Review of basic course concepts De-stress and fun Inner Life of the Cell http://www.youtube.com/watch?v=zrXykvorybo http://www.offthemark.com/cartoons/stages/ http://www.maniacworld.com/inner-life-of-a-cell.html Cell Topics Assigned Active Transport Apoptosis Cell Membrane Chromosome Cytoskeleton Enzymes Mitochondria Mitosis Nucleus Transcriptional factors Glycolysis Active transport Vesicular transport Signaling pathways Activated carrier molecules Transcription factors Questionnaire Results 1) Time Investment Less than two hours: Two to five hours: Five to eight hours: More than eight hours: 3 16 20 16 2) Origin of Idea Class Lecture: Textbook: Previous Interest: Other: 10 7 11 27 3) Anticipated Grade A: B: C: D: F: 93% (56%) 5% (24%) 2% (4%) 0% (4%) 0% (12%) Likert Scale for question 4 (A-F) Seven Point scale Not at all – Entirely Dependent A) Use of primary sources: 4.3 B) Helpfulness of an artistic or other talent: 4.7 C) Usefulness of textbook: 5.3 D) Usefulness of notes/power-points: 5.3 E) Assistance in preparing project: 2.6 F) Did your project to understanding of course material: 5.7 “Absolutely wonderful! I can really think of no suggestions. The project in its entirety, I feel, is a great success. It gives us as students a chance to relax and have fun, while being able to not only to learn but showcase Our hidden talents. “Cell-tasia” greatly impacted my view on Cell Biology as a class. Biology isn’t some boring subject about abstract things; it is the proven, although viewed as theoretical, way that the body is composed and functions. This class greatly contributed to my passion to become a doctor, and without it I could still be wondering…..is this what I want to do?” “The due dates on the reports helped me to think about my project ahead of time instead of waiting until the last minute”. “Get the faculty more involved. It’s always fun and encouraging to see a teacher getting involved with the students”. “Celltasia really helps you understand the world of a cell right before the final”. “Be passionate; enjoy researching and learning about the material”. “When presenting your project, make sure the materials you are using are clear and the audience understands what concept you are trying to convey”. “Brainstorm and don’t rule out “crazy” projects because they are the projects everyone remembers” “Try using an artistic medium that is completely new to you. It will force you to think of your topic from a different perspective and help you understand it more thoroughly”. “Definitely test your materials way ahead of time to make sure they work!” “The only thing that may help would be some way of ensuring that the students take the presentations more seriously.” “Less flexibility, choice of an artistic medium for presentations. Impossible to have useful grading rubric for many different forms of art. I felt the absence of a definite system of how I was evaluated was very frustrating in preparation (although I got an A). Would have done a better job if given a definite objective. I felt some people were given good grades for what I felt were bad presentations and visa-versa”. “While having food is enjoyable, I feel as though those who made food for their project don’t contribute as much as others with an actual demonstration/presentation. Also, I felt as though I understood the concepts that were put forth via a presentation much more than when someone just made a cake with a diagram on it, etc…..” Sources Alberts B, Johnson A, Lewis J, Raff M, Roberts, K and Walter P. (2008) Molecular Biology of the Cell, 5th edition. New York; Garland Science. Turro, N.J. (2005) Molecular structure as a blueprint for supramolecular structure chemistry in confined spaces. PNAS 109 (5):10766-10770.