RAG LIST OF DRUGS FOR NHS BLACKPOOL CCG Use the hyperlink alphabet to move to the relevant drug or Ctrl+F to "Find on this page To open a hyperlink document as a separate tab window in Internet Explorer, press Ctrl and cli hyperlink. HYPERLINKSA F K P U Drug name 3,4 DIAMINOPYRIDINE (BASE) ABATACEPT B G L Q V C H M R W D I N S XYZ Further information Comments NHS BLACKPOOL CCG Status Lambert Eaton Myasthenic Syndrome (LEMS) Anti-TNF (Cytokine inhibitor) or related drug. NICE TA195 NICE TA280- Patient Access Scheme (Replaces TA234) Red Funded by Specialised Commissioning for JIA & Paediatric indications (where adult TA exists) ABIRATERONE ACITRETIN Oral Retinoid for Psoriasis ACLIDINIUM BROMIDE B Red B Red B Red B Black ADALIMUMAB Anti-TNF (Cytokine inhibitor) or related drug ADALIMUMAB For moderate to severe ulcerative colitis NICE TA262 (terminated) Funded by Specialised Commissioning for Paediatric indications (where adult TA exists) As above Red B Black B Funded by Specialised Commissioning for Hep B ADEFOVIR Indication: Viral Hepatitis AFLIBERCEPT Wet AMD under Patient Access Scheme (NICE TA294) Red AFLIBERCEPT Macular Oedema (Central Retinal Vein Occlusion) under Patient Access Scheme (NICE TA305) Red AFLIBERCEPT Colorectal Cancer (metastatic) (NICE TA307) AGOMELATINE Indication: Major Depression Prior approval and restricted use within LCFT ALEMTUZUMAB Anti-TNF (Cytokine inhibitors) including related drugs ALISKIREN BFWH Tertiary Centre ALITRETINOIN ALTEPLASE Specialised Commissioning B Black Black B Red B Amber B Topical preparation for eczema Red B NICE TA264 Red B Black B Red B Red B Black B Funded by Specialised Commissioning for MS & Pre transplant immunosuppression AMIFRAMPRADINE (FIRDAPSE®) AMPHOTERICIN IV Red IV Anti-fungal Drug ANAGRELIDE ANAKINRA Rheumatoid arthritis (NICE TA72) Anti-TNF (Cytokine inhibitors) or related drug ANASTRAZOLE Early Breast Cancer (hormonal treatment) (NICE TA112) Funded by Specialised Commissioning Amber ANTIBIOTICS IV RED Unless there are specific arrangements or service in place that allow this Red B ANTI-CANCER THERAPY FOR MALIGNANT DISEASE (NOT INCLUDING HORMONAL TREATMENTS) Chemotherapy usually IV requiring monitoring during administration. Includes oral anti-cancer therapy for malignant disease Red B Red B Red B Funded by Specialised Commissioning ANTI-HIV TREATMENTS APIXABAN Venous thromboembolism after hip and/or knee surgery (NICE TA245) APIXABAN Prevention of stroke and systemic embolism in people with nonvalvular atrial fibrillation (NICE TA 275) Green APOMORPHINE ARIPIPRAZOLE ASENAPINE Amber Shared Care Moderate to severe manic episodes in adolescents with bipolar disorder (NICE TA292) Red Atypical antipsychotic ATOMOXETINE ATORVASTATIN (CHEWABLE) Lipitor chewable AURANOFIN BEVACIZUMAB Red B Amber B Black B Amber Shared care guidelines AZATHIOPRINE For use in combination with capecitabine for the first-line treatment of metastatic breast cancer (NICE TA263) B Amber Shared Care Black B B B Colorectal cancer (metastatic) (NICE TA212 & NICE TA242) BEVACIZUMAB Black B Ovarian cancer (NICE TA284 & TA285) BOCEPREVIR Hepatitis C (NICE TA253) Funded by Specialised Commissioning Red BOSENTAN Pulmonary hypertension drug Funded by Specialised Commissioning Red BOSUTINIB Chronic Myeloid Leukaemia NICE TA299 Specialised Commissioning B B Black For Migraine - NICE TA260 BOTULINUM TOXIN A BRIMONIDINE GEL Red Chronic anal fissure Facial erythema of rosacea Black BRINZOLAMIDE EYE DROPS Amber BUPRENORPHINE PATCHES Amber BUPRENORPHINE SUBLINGUAL TABLETS Opiate addiction (NICE TA114) CINRYZE (C1-ESTERASE INHIBITOR) Hereditary angioedema (acute treatment only) Prescribed in SMS service Funded by Specialised Commissioning Grey Red CALCIUM FOLINATE TABLETS Red Combination therapy for Type 2 Diabetes as per NICE TA315 Gouty arthritis NICE TA281 – terminated appraisal CANAKINUMAB Juvenile Idiopathic Arthritis NICE TA302 Green Funded by Specialised Commissioning B B Amber CALCITONIN CANAGLIFLOZIN B Black B B B CANNABIS SPRAY (SATIVEX®) Red CAPD FLUIDS Red CAPREOMYCIN Antituberculosis drug Red CAPSAICIN PATCH CERTOLIZOMAB Black Anti-TNF (Cytokine inhibitor) or related drug Moderate to severe RA Funded by Specialised Commissioning for Paediatric indications (where Adult TA exists) CICLOSPORIN Red Amber Shared Care CIDOFOVIR Anti-Cytomegalovirus drug CILOSTAZOL Peripheral Vasodilator (NICE TA22). NEW PATIENTS AFTER MAY 2011. (Patients on treatment before this may continue if clinically indicated) CINACALCET Funded by Specialised Commissioning Red Black Amber CLOZAPINE Atypical antipsychotic. Monitoring required COLESEVELAM Primary hypercholesterolaemia (licenced indication) Black COLESEVELAM Intractable diarrhoea under specialist initiation (off-licence) Amber COLISTIN Antibiotic nebulised Amber Red B B B B B B B B B B B B COLISTIMETHATE SODIUM COMBIDART In combination with Tobramycin dry powder for inhalation, for treating pseudomonas lung infection in cystic fibrosis TA276 Specialised Commissioning Moderate to severe BPH Amber CO-PROXAMOL Black CO-TRIMOXAZOLE CRIZOTINIB Red Red Lung Cancer (non-small-cell, Anaplastic-lymhoma-Kinase positive, previously treated) – NICE TA296 Funded by Specialised Commissioning CYCLOPHOSPHAMIDE Antituberculosis drug DABIGATRAN Venous thromboembolism after hip and knee replacement (NICE TA157) DABIGATRAN Atrial Fibrillation - stroke prevention (NICE TA249) DABRAFENIB Unresectable or metastatic BRAF V600 mutation-positive melanoma DALTEPARIN for prophylaxis of DVT Red Red Not First Line – See Lancs Consensus statement Funded by Specialised Commissioning Green RED Unless there are specific arrangements or service in place that allow this DAPAGLIFLOZIN Type 2 Diabetes – combination therapy as per NICE TA288 B B B B B Red Amber DALTEPARIN for treatment of DVT B Black Amber CYCLOSERINE B Red Green B B DARBEPOETIN DASATINIB Red Leukaemia (chronic myeloid) (NICE TA241 & NICE TA251) Funded by Specialised Commissioning DEFERIPRONE DECITABINE Acute myloid leukaemia (terminated appraisal TA270) DEGARELIX Funded only under patient access scheme DENOSUMAB DENOSUMAB Black Black Amber For osteoporosis as per (NICE TA 204) Amber Bone metastasis from solid tumours but only with the Patient Access Scheme (NICE TA265) Red Funded by Specialised Commissioning DESFERASIROX DESFERRIOXAMINE Ozurdex Implant as per NICE TA229 DIMETHYL FUMARATE Relapsing-remitting Multiple Sclerosis NICE TA320 Red Funded by Specialised Commissioning DISULFIRAM DORNASE ALFA Red Red DEXAMETHASONE IMPLANT DOLASETRON Red Cystic Fibrosis Amber Funded by Specialised Commissioning B B B B B B B B B Red Amber Antiemetic (5HT3 antagonists) B Amber B B B Prescribing Information Sheet Available DRONEDARONE DYMISTA (FLUTICSONE/AZELASTINE) NASAL SPRAY Moderate-severe allergic rhinitis ECULIZUMAB Atypical haemolytic uraemic syndrome Paroxysmal nocturnal haemoglobinuria EFLORNITHINE As per Pan Lancashire Commissioning Policy number 31 on cosmetic procedures ONLY ELTROMBOPAG Chronic immune (idiopathic) thrombocytopenia purpura (NICE TA293) Amber Black Funded by Specialised Commissioning Red Black Funded by Specialised Commissioning ENTACAPONE ENZALUTAMIDE Metastatic hormone-relapsed prostate cancer- NICE TA316 EPLERENONE NYHA Class II HF Funded by Specialised Commissioning Red Funded by Specialised Commissioning Red Grey ERYTHROPOIETIN ALFA, BETA & DELTA Red ESLICARBAZEPINE Black ETANERCEPT Anti-TNF (Cytokine inhibitors) including related drugs ETHAMBUTOL Antituberculosis drug EVEROLIMUS Renal Cell Carcinoma (TA219) Breast Cancer (NICE TA295) Funded by Specialised Commissioning for JIA & Paediatric indications (where adult TA exists) B Red Amber ENTECAVIR B Red Red Black B B B B B B B B EXENATIDE Green FAMPRIDINE M.S. FENTANYL SPRAY PecFent Intranasal Spray FESOTERODINE Over active bladder – awaiting NICE FINGOLIMOD For the Treatment of Highly Active Relapsing–Remitting Multiple Sclerosis (TA254) FLUOCINOLONE INTRAVITREAL IMPLANT Chronic diabetic macular oedema (NICE TA301 available with Patient Access Scheme) Funded by Specialised Commissioning Grey Red Funded by Specialised Commissioning Red Red Amber FLUTICASONE/FORMOTEROL INHALER (FLUTIFORM) Black Moderate-severe allergic rhinitis FOSCARNET Anti Cytomegalovirus drug GALANTAMINE GANCICLOVIR Funded by Specialised Commissioning GLATIRAMER Red Amber Anti-Cytomegalovirus drug B B B B B Black FULVESTRANT Acetylcholinesterase Inhibitor for mild to moderate dementia B B FLUOROURACIL (5FU) CREAM FLUTICASONE/AZELASTINE NASAL SPRAY (DYMISTA) B Shared care Guidelines from LCFT Amber Shared Care Funded by Specialised Commissioning Red Funded by Specialised Commissioning Red B B B B B GLUCOSAMINE GLYCERYL TRINITRATE 0.4% OINTMENT Black Anal Fissures Black GLYCOPYBROMIDE (SEEBRI® BREEZHALER) Green GOLIMUMAB Psoriatic Arthritis NICE TA 220 GOLIMUMAB Moderate to severe ulcerative Colitis Funded by Specialised Commissioning for Paediatric indications (where adult TA exists) Red Amber GRAZAX® Black HERPES ZOSTER VACCINE – LIVE (ZOSTAVEX) Black HYDROCORTISONE MODIFIED RELEASE (PLENADERM) Adrenocortical insufficiency HYDROXYCARBAMIDE Dermatology/Psoriasis Amber Shared Care HYDROXYCARBAMIDE Haematology Amber Shared Care Black HYDROXYCHLOROQUINE Amber Oral ICATIBANT ACE Induced Angioedema. Treatment only. B B B Black GONADORELIN IBANDRONIC ACID B Amber Funded by Specialised Commissioning Red B B B B B B B B B ILOPROST nebulised Pulmonary hypertension drug IMMUNOGLOBULIN IV INFUSION Unless there are specific arrangements or service in place that allow this INFLIXIMAB Anti-TNF (Cytokine inhibitors) or related drug INOSITOL NICOTINATE Peripheral Vasodilator NICE TA223. NEW PATIENTS AFTER MAY 2011. (Patients on treatment before this may continue if clinically indicated) Funded by Specialised Commissioning Red Funded by Specialised Commissioning for: Paediatric RAindications (where adult TA exists); Interstitial lung disease;Crohns disease in children;Renal; Sarcoidosis; Uveitis (paediatric) INSULIN DEGLUDEC INTERFERON BETA IPILIMUMAB Red Black Funded by Specialised Commissioning INTERFERON ALFA Red Red B B B B B Black DoH rebate scheme running through specialist centres only Funded by Specialised Commissioning Red For previously treated advanced melanoma (NICE TA268) Red B B For previously untreated advanced melanoma (NICE TA319) IRON DEXTRAN ISONIAZID Red Antituberculosis drug Red ISOTRETINOIN oral IVABRADINE IVACAFTOR Red For heart failure NICE TA267 Cystic Fibrosis Amber Funded by Specialised Commissioning Red B B B B IV INFUSIONS RED Unless there are specific arrangements or service in place that allow this Red LACOSAMIDE Consultant Neurologist Initiation Amber LAMIVUDINE Chronic Hepatitis B Red (Funded by Specialised Commissioning for cancer only – Red status in this indication) LANREOTIDE Amber LANTHANUM Amber LEFLUNOMIDE Amber Shared Care LENALIDOMIDE Myelodysplastic syndromes – NICE TA322 LIDOCAINE Patches 3rd line for Post Herpetic Neuralgia LINACLOTIDE LINEZOLID Funded by Specialised Commissioning Red Red B B B B B B B Black Consultant microbiologist advice Red LIOTHYRONINE Amber LIRAGLUTIDE Amber LITHIUM LIXISENATIDE B Amber Shared Care Recommended as an option only to add-on to basal insulin when a licensed GLP-1mimetic is clinically indicated but twice daily product not appropriate Green (restricted) B B B B LOW MOLECULAR WEIGHT HEPARIN prophylaxis Prophylaxis Pregnancy, DVT and PE Amber LOW MOLECULAR WEIGHT HEPARIN treatment Red LOXAPINE Acute agitation and disturbed behaviours associated with schizophrenia and bipolar disorder (NICE TA286 – Terminated appraisal) LUBIPROSTONE Chronic Idiopathic constipation – NICE TA318 MANNITOL DRY POWDER NICE TA266 CF Amber Funded by Specialised Commissioning MELATONIN Unlicensed formulations Red MERCAPTAMINE (CYSTEAMINE) EYE DROPS Red MERCAPTOPURINE Amber Shared Care MESNA TABLETS Red METHOTREXATE IM/IV Anti-cancer therapy for malignant disease METHOTREXATE SC INJECTION Red Amber Opiate addiction (NICE TA114) B Black MELATONIN licensed Circadin® METHADONE B Prescribed in SMS service B B B B B Amber Red Shared care guidelines from BFW B Amber Shared Care B B METHYLNALTREXONE Opioid-induced bowel dysfunction in people with advanced illness receiving palliative care NICE TA277 Black METHYLPHENIDATE Amber MIDAZOLAM BUCCAL LIQUID Amber MIDODRINE MIRABEGRON Red Overactive Bladder (where antimuscarinic agents are contraindicated or not effective) NICE TA290 Amber MYCOPHENOLATE Renal transplantation - immunosuppressive regimens (NICE TA85 and TA99) Amber MYCOPHENOLATE Dermatology and Rheumatology patients Red MYCOPHENOLATE SODIUM (MYFORTIC®) Renal transplantation immunosuppressive regimens for children and adolescents NICE TA99 Black N-ACETYLCYSTEINE NALTREXONE OCRIPLASMIN OCTREOTIDE Red Low dose unlicensed treatment for MS Substance misuse (NICE TA115) Vitreomacular Traction B B Green MODAFINIL NALTREXONE B Black Prescribed in SMS service B B B B B B Amber Red Amber Shared Care B OCTREOTIDE OMALIZUMAB For unlicensed use Severe Persistent Allergic Asthma NICE TA278 – Patient Access Scheme (replaces TA133 & TA201)) (Funded by Specialised Commissioning for cancer use only) Red Funded by Specialised Commissioning Red ONDANSETRON Antiemetic (5HT3 antagonists) Amber PALIPERIDONE Atypical antipsychotic Non formulary item with LCFT Black Funded by Specialised Commissioning PALIVIZUMAB PAMIDRONATE IV Unless there are specific arrangements or service in place that allow this Red Red PARICALCITOL Red PEGFILGASTRIM Red Funded by Specialised Commissioning PEGINTERFERON ALFA PEGINTERFERON ALFA in combination with Ribavarin Hepatitis C in Children & Young People NICE TA300 PEGLOTICASE Gout (tophaceous, severe debilitating, chronic) NICE TA291 Specialised Commissioning B B B B B B B Red Black Funded by Specialised Commissioning PEGVISOMANT Red B Red B B PELVIC FLOOR TONER PENTOXYFYLLINE Black Peripheral Vasodilator NICE TA223. NEW PATIENTS AFTER MAY 2011. (Patients on treatment before this may continue if clinically indicated) Black B PENICILLAMINE Amber Shared Care PERAMPANEL When other treatment options recommended by NICE CG137 have failed or been fully considered Amber PIRFENIDONE Idiopathic pulmonary fibrosis NICE TA282 Red PIXANTRONE Monotherapy for Lymphoma (nonHodgkin’s, relapsed, refactory) (NICE TA306) PRASUGREL ACS in PCI with aspirin for 12 months. (NICE TA317 – updating TA182) PREDNISOLONE MR Lodotra Specialised Commissioning B Red Amber B Black B PRESERVISION Black B PROBIOTICS Black PROMIXIN Antibiotic nebulised Amber PRUCALOPRIDE NICE TA211 Amber PYRAZINAMIDE Antituberculosis drug Red RANIBIZUMAB Wet AMD (NICE TA 155) Red Diabetic macular oedema (NICE TA274 – replaces TA237) Patient Access Scheme RANIBIZUMAB Macular oedema (RVO) NICE TA283 Patient Access Scheme Choroidal Neovascularisation secondary to pathological myopia Red B B B B B (NICE TA298) BFW Tertiary Centre. Information sheet available RANOLAZINE RASAGILINE M.S. Black Funded by Specialised Commissioning RASBURICASE RESPARATE RhG-CSF Amber Red Black Human granulocyte-colony stimulating factors Red Funded by Specialised Commissioning RIBAVARIN Red RIBAVARIN In combination with Peginterferon Hepatitis C in Children & Young People NICE TA300 RIFABUTIN Antituberculosis drug Red RIFAMPICIN Antituberculosis drug Red Red ANCA Vasculitis Systemic Lupus Erythematosus RITUXIMAB (in combination with glucocorticoids) Vasculitis (anti-neutrophil cytoplasmic antibody-associated) RITUXIMAB Anti-TNF (Cytokine inhibitors) or related drug B B B B B Specialised Commissioning RISPERIDONE DEPOT INJECTION RITUXIMAB B Specialised Commissioning Policy Specialised Commissioning Funded by Specialised Commissioning Red B B B B Red Red B RIVAROXABAN Venous thromboembolism after hip and knee surgery (NICE TA170) RIVAROXABAN Atrial Fibrillation - stroke prevention (NICE TA256) Red Not First Line – See Lancs Consensus Statement Green For treatment of DVT and prevention of DVT and pulmonary embolism (NICE TA261) RIVAROXABAN Amber B B B Prevention of pulmonary embolism and prevention of recurrent venous thromboembolism (NICE TA287) Shared care Guidelines from LCFT RIVASTIGMINE Acetylcholinesterase Inhibitor for mild to moderate dementia ROFLUMILAST (NICE TA 244) ROMIPLOSTIM For ITP (NICE TA221) Red ROPINEROL Parkinson's disease Amber ROPINEROL Restless legs syndrome Green ROTIGOTINE PATCHES Parkinsons Amber Amber Shared Care Black RUFINAMIDE Amber RUXOLITINIB Myelofibrosis (Splenomegaly, symptons) Black SELENIUM/ZINC For Post Bariatric Surgery Black SERTINDOLE Atypical antipsychotic. Monitoring required SEVELAMER HYDROCHLORIDE For hyperphosphataemia in renal patients Red Funded by Specialised Commissioning in renal dialysis Amber B B B B B B B B B SEVELAMER CARBONATE For hyperphosphataemia in renal patients SILDENAFIL for Pulmonary Hypertension Pulmonary hypertension services are nationally commissioned at specialist centres who undertake all prescribing SILK GARMENTS Funded by Specialised Commissioning Atopic eczema Pulmonary hypertension services are nationally commissioned at specialist centres who undertake all prescribing Amber Shared Care Narcolepsy with cataplexy Black SOMATROPIN SORAFENIB Amber Red SODIUM AUROTHIOMALATE IM INJECTION SODIUM OXYBATE Red Black Funded by Specialised Commissioning (Rapamycin for transplant immunosuppression only – RED status) SIROLIMUS SITAXENTAN Black Amber Renal cell carcinoma (TA178) and Hepatocellular carcinoma (advanced and metastatic) (NICE TA189) Black STIRIPENTOL NICE CG 137 Jan 2012 - tertiary care only Red STREPTOMYCIN Antituberculosis drug Red SULFASALAZINE Rheumatology & Gastroenterology Funded by Specialised Commissioning for Transplant immunosuppression only TACROLIMUS TADALAFIL Amber Shared Care Benign prostatic hyperplasia (terminated appraisal TA273) Funded by Specialised Commissioning for pulmonary arterial hypertension Amber Black B B B B B B B B B B B B B B TAFLUPROST Amber TAPENTADOL Opioid analgesic Black TARGINACT Oxycodone/naloxone for moderate to severe pain Black TAURINE (unlicensed supplement) Prevention of taurine deficiency in Cystic Fibrosis Black TELAPREVIR Hepatitis C (NICE TA252) TELBIVUDINE TENOFOVIR Chronic Hepatitis B (NICE TA173) TERIFLUNOMIDE Multiple Sclerosis (relapsing) (NICE TA303) TERIPARATIDE Funded by Specialised Commissioning Red Funded by Specialised Commissioning Red B B B B Specialised Commissioning Specialised Commissioning Red Red TESTOSTERONE DEPOT INJ B Amber TESTOSTERONE HRT Green TESTOSTERONE GEL (TESTOGEL) Adult onset hypogonadism with erectile dysfunction Amber TESTOSTERONE PATCHES Black TESTOSTERONE IMPLANT Red B B B B B THALIDOMIDE Specialist initiation & monitoring due to teratogenicity risk TICAGRELOR ACS for up to 12 months with aspirin (NICE TA236). NOT FOR FIRST LINE. Funded by Specialised Commissioning See Lancs position statement Red Amber TINZAPARIN for prophylaxis Amber TINZAPARIN for treatment Red TOBRAMYCIN TOBI Podhaler Only under The Patient Access Scheme. Funded by Specialised Commissioning Red TOBRAMYCIN nebulised Antibiotic nebulised Funded by Specialised Commissioning Red TOCILIZUMAB S/C available for RA indications TOCILIZUMAB Anti-TNF (Cytokine inhibitors) or related drug – as per NICE Funded by Specialised Commissioning for JIA & Paediatric indications (where adult TA exists) Red Funded by Specialised Commissioning for hyponatraemia & other endocrine uses For SIADH TRABECTEDIN For ovarian cancer NICE TA 222 Black TROPISETRON Antiemetic (5HT3 antagonists) Amber Shared care guidelines from LCFT Anti-TNF (Cytokine inhibitors) including related drugs. Plaque psoriasis NICE TA180 B B B B Red TOLVAPTAN USTEKINEMAB B Red TOLCAPONE TRYPTOPHAN (LTRYPTOPHAN) B Black Amber Amber B B B B B Funded by Specialised Commissioning VALGANCICLOVIR Anti Cytomegalovirus drug VARDENAFIL Orodispersible tablets Black VEMURAFENIB Advanced BRAF V600 mutation positive melanoma (NICE TA269) Red VINFLUNINE Advanced transitional cell carcinoma of the urothelial tract (NICE TA272) Black Funded by Specialised Commissioning VORICONAZOLE ZOTEPINE Atypical antipsychotic Non formulary item with LCFT Red Red Red B B B B B B