Philadelphia University
Faculty of Pharmacy
Lecturer : Ms.Hiyam Al-jaber
Coordinator:
Internal Examiner:
Department of Clinical Sciences
Student Name:
Student Number:
Course Name: Pathophysiology
Semester of Academic Year
Course Number: 0530271 Section: 1
Date:
First
Duration of Exam: 50 min
-----------------------------------------------------------------------------------------------------------Information for Candidates
This examination paper contains 3 questions in 2 pages, totalling 20 marks.
Notes to Candidates
1. You should attempt all questions.
2. You should write your answers clearly
-----------------------------------------------------------------------------------------------------------Q1) Select the most appropriate answer of the following:
1.Melena is an indication of:
A. upper gastrointestinal bleeding
C. both
B. lower gastrointestinal bleeding
D. neither
2.The most common cause of upper gastrointestinal hemorrhage (hematemesis or melena)
is:
A. esophageal varices
B. gastric carcinoma
C. peptic ulcer
D. gastritis
3.Occult fecal blood test would be helpful in discovering:
A. colonic carcinoma
B. malabsorption syndrome
C. both
D. neither
4.Celiac disease is the result of:
A. bacterial destruction of small bowel mucosa
C. reaction to gluten
E. lymphatic obstruction
B. poor dietary practices
D. a primary enzyme deficiency
5. Celiac disease is best described as a/an:
A. mucosal disease of the small intestine producing malabsorption
B. asymptomatic disease of the left colon
C. condition associated with reflux esophagitis
D. type of inflammatory bowel disease
E. common cause of intestinal obstruction
6. Weight loss, steatorrhea, and marked atrophy of villi in the jejunum are seen in:
A. achalasia
B. Whipple’s disease
C. celiac disease
D. tracheo-esophageal fistula
E. Crohn’s disease
7. A 52-year-old female with a palpable right upper quadrant mass developed weight loss
and painless jaundice 2 months ago. She most likely has:
A. a positive Trousseau’s sign
B. Zollinger-Ellison’s syndrome
C. acute cholecystitis
D. Gardner’s syndrome
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8. Most of the amount of billirubin is derived from:
a. RBCs.
b. Bone marrow.
c. Muscles.
d. All.
9- Which of the following viral causes of hepatitis is transmitted by contaminated food or
water?
a- Hepatitis D
b- Hepatitis E
c- Hepatitis C
d-Hepatitis B
10- Hepatitis D is commonly associated with what other type of viral hepatitis?
a- Hepatitis D
b- Hepatitis E
c- Hepatitis C
d-Hepatitis B
11- Which of the following causes of viral hepatitis is most common worldwide?
a- Hepatitis D
b- Hepatitis E
c- Hepatitis C
d-Hepatitis B
12- The area of the brain located in the fourth ventricle, which is usually associated with
chemically induced vomiting, is the
A)salivation center.
B)chemoreceptor trigger zone.
C)vomiting center.
D)respiratory center.
13- Typical symptoms of constipation include all of the following EXCEPT:
a- Abdominal distension.
b- Hard stool.
c- Straining.
d- None of the above.
14- The commonest cause of peptic ulcers is:
a- NSAIDs.
b- H.pylori.
c- Stress ulcer.
d- Smoking.
Q2) Write down 4 risk factors of PUD.
1- Spicy diet.
2- Smoking.
3- Alcohol drinking.
Q3) mention 2 mechanisms of estrogen induced gallstones.
1- Estrogen will increase bile concentration.
2- Estrogen will decrease gallbladder motility.
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4- Steroid therapy.