Mrs. Stewart Biology I standard REVIEW: Cell Cycle Interphase G1, S, and G2 M-phase (mitosis) P-M-A-T-C Mitosis Asexual reproduction Produces 2 identical daughter cells Daughter cells are diploid Daughter cells are identical to parent/mother cell What differences can you see? • How many sets of chromosomes are in the cells that Meiosis produces? • How many cells does Meiosis produce? • How many divisions occur in Meiosis? MEIOSIS: The process of creating a gamete Chromosomes come in matching sets -these are called homologous pairs Karyotype after DNA replication Notice how each chromosome has duplicated itself. Final Products: Mitosis Somatic cells in your body have two sets of chromosomes they are called DIPLOID Meiosis Gametes (Sex cells-sperm and eggs) only have one set (half) of chromosomes - they are called HAPLOID What are the steps? Phases of Meiosis I Prophase I Metaphase I Anaphase I Telophase I Cytokinesis Interkinesis Phases of Meiosis II Prophase II Metaphase II Anaphase II Telophase II Cytokinesis DNA replicates Interphase Makes the diploid (2n) cell now be (4n) n=number of chromosome sets/pairs Example: humans have 46 total chromosomes, so our diploid number is 2n or 2(23) where n = 23 Prophase I • Homologous chromosomes pair up (forming a tetrad) - Mom & Dad go on a date • Crossing over occurs • Chromatids MAY exchange portions of DNA • Leads to genetic variances Metaphase I Spindle fibers attach to the chromosomes Homologous chromosomes line up in the middle of the cell Anaphase I • Fibers pull the homologous chromosomes toward opposite ends of the cell Telophase I and Cytokinesis • Nuclear membranes form • Cell separates into two new cells Meiosis II The daughter cells from Meiosis I divide again WITHOUT replicating their chromosomes That leads to 4 gametes, each with half the number of chromosomes (haploid) as the original “mother” cell Metaphase II Spindle fibers attach to the chromosomes chromosomes line up in the middle of the cell – similar to how they do in Mitosis Anaphase II • Fibers pull the sister chromatids toward opposite ends of the cell Telophase II and Cytokinesis • Nuclear membranes form • Both cells separate – forming 4 new haploid cells Oogenesis – meiosis in human female reproductive cells – makes eggs (ovum) • Forms one egg cell with a large supply of stored nutrients. • The other 3 gametes produced, called polar bodies, disintegrate. Spermatogenesis – meiosis in human male reproductive cells to make sperm (spermatazoa) • Produces 4 viable gametes • All 4 gametes produce a long whip-like tail Meiosis: Cell division necessary for sexual reproduction Produces 4 daughter cells Daughter cells are Haploid Daughter cells are gametes (sexual repro. cells) 2 nuclear/cellular divisions Vital to maintain correct number of offspring in sexually reproducing organisms Crossing over = opportunity for genetic variability Differentiate Mitosis Meiosis Asexual reproduction Used for sexual reproduction Produces 2 daughter cells Produces 4 daughter cells Daughter cells are diploid Daughter cells are Haploid Daughter cells are Daughter cells are genetically identical to each other and to parent cell Produces somatic cells One cell/nuclear division different from each other, and from parent cell Produces gametes Two nuclear/cellular divisions Human chromosomal diseases Down’s syndrome (extra chromosome #21) Turner’s syndrome (missing or incomplete X chromosome in girls) Klinefelter’s syndrome (males that have an extra X chromosome [XXY]) **Mistake in meiosis can lead to an incorrect chromosomal number, causing consequences for offspring** Video Meiosis square dance