- Vanderbilt University Medical Center

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How to understand and use National

Ambulatory Medical Care Survey

(NAMCS) and National Hospital

Ambulatory Medical Care Survey

(NHAMCS) data for clinical research

Yuwei Zhu

10-29-2004

Dept of Biostatistics

1

Overview

I. Survey Background

II. Survey Methodology

III. Technical Considerations

IV. Getting the Data – Using Raw Data Files

V. Example

VI. Data Analysis – SAS, STATA, SUDAAN

VII. Other Public Domain Data

2

NAMCS and NHAMCS

Performed by:

 Centers for Disease Control and

Prevention (CDC)

 National Center for Health

Statistics, Division of Health Care

Statistics, and National Health Care

Survey

3

National Ambulatory Medical Care

Survey (NAMCS) History

 Survey began in 1973

 Annual data collection through 1981

 Conducted in 1985

 Annual began again in 1989

4

NAMCS

 Classified by the American Medical

Association and the American

Osteopathic Association as delivering

“office-based, patient care”

 Healthcare providers within private, non –hospital-based clinics and health maintenance organizations (HMOs) are within the scope of the survey

5

NAMCS

 Patient visits made to the offices of non – federally employed physicians

– Excluding:

 Anesthesiology

 Radiology

 Pathology

6

In-Scope NAMCS locations

 Freestanding clinic

 Federally qualified health center

 Neighborhood and mental health centers

 Non-federal government clinic

 Family planning clinic

 HMO

 Faculty practice plan

 Private solo or group practice

7

Out-of-Scope NAMCS locations

 Hospital EDs and OPDs

 Ambulatory surgicenter

 Institutional setting (schools, prisons)

 Industrial outpatient facility

 Federal Government operated clinic

 Laser vision surgery

8

NAMCS

NAMCS uses a multistage probability sample design to obtain

– Primary sampling units (PSUs)

– Physician practices within the PSUs

– Patient visits within physician practices

9

Sample design - NAMCS

112 PSUs (counties)

– Counties

– Groups of counties

– County equivalents (such as parishes or independent cities)

– Towns

– Townships

Nonfederally employed, office-based physicians stratified by specialty, 3,000 physicians

About 30 visits per doctor over a randomly selected 1-week period, 25,000 visits

10

National Hospital Ambulatory Medical

Care Survey (NHAMCS) History

 Survey began in 1992

 Annual data collection

11

NHAMCS

 National sample of visits to the EDs and outpatient departments of noninstitutional general and short-stay hospitals in the

United States

 Excluded hospitals:

– Federal

– Military

– Veterans Administration

12

NHAMCS

This survey uses a 4-stage probability design with samples

–geographically defined areas

–hospitals within these areas

–clinics within the hospital

–patient visits within clinics.

The first stage is similar to NAMCS

13

Sample design - NHAMCS

112 PSUs (counties)

Panel of 600 non-Federal, general or short stay hospitals

Clinics (OPDs) and emergency service areas (EDs), 400 EDs and 250 OPDs

About 200 visits per OPD,

100 per ED over random 4-week period,

37,000 ED and 35,000 OPD visits

14

NHAMCS Scope

 OPD was intended to be parallel to the NAMCS in the hospital setting

 General medicine, surgery, pediatrics, ob/gyn, substance abuse, and “other” clinics are inscope

 Ancillary services are out of scope

15

Data Items

 Patient characteristics

– Age, sex, race, ethnicity

 Visit characteristics

– Source of payment, continuity of care, reason for visit, diagnosis, treatment

 Provider characteristics

– Physician specialty, hospital ownership…

 Drug characteristics added in 1980

– Class, composition, control status, etc.

16

Repeating fields (from text entries)

 Up to 3 fields each…

– Reason for visit

– Physician’s diagnosis

– Cause of injury

 Diagnostic services (6 fields)

 Surgical procedures (2 fields)

 Medications (6 fields)

– Drug ingredients (5 fields)

– Therapeutic class (3 fields – 2002 on)

17

Coding Systems Used

 Reason for Visit Classification (NCHS)

 ICD-9-CM for diagnoses, causes of injury and procedures

 Drug Classification System (NCHS)

 National Drug Code Directory

18

Drug Data in NAMCS/ NHAMCS

What is a “Drug Mention” ?

Any of up to 6 medications that were ordered, supplied, administered, or continued during the visit.

Respondents are asked to report trade names or generic names only (not dosage, administration, or regimen).

19

Drug Characteristics

 Generic Name (for single ingredient drugs)

 Prescription Status

 Composition Status

 Controlled Substance Status

 Up to 3 NDC Therapeutic Classes (4-digit)

 Up to 5 Ingredients (for multiple ingredient drugs)

20

Some User Considerations

NAMCS/NHAMCS sample visits, not patients

No estimates of incidence or prevalence

No state-level estimates

Not sampled by setting or by nonphysician providers

May capture different types of care for solo vs. group practice physicians

21

Data uses

 Understand health care practice

 Examine the quality of care

 Track certain conditions

 Find health disparities

 Measure Healthy People 2010 objectives

 Serve as benchmark for states

22

Data users

 Over 100 journal publications in last 2 years

 Medical associations

 Government agencies

 Health services researchers

 University and medical schools

 Broadcast and print media

23

Sample Weight

 Each NAMCS record contains a single weight, which we call Patient Visit Weight

 Same is true for OPD records and ED records

 This weight is used for both visits and drug mentions

24

Reliability of Estimates

 Estimates should be based on at least 30 sample records AND

 Estimates with a relative standard error

(standard error divided by the estimate) greater than 30 percent are considered unreliable by NCHS standards

 Both conditions should be met to obtain reliable estimates

25

How Good are the Estimates?

 Depends on what you are looking at. In general,

OPD estimates tend to be somewhat less reliable than NAMCS and ED.

 Since 1999, Advance Data reports include standard errors in every table so it is easy to compute confidence intervals around the estimates.

26

Sampling Error

 NAMCS and NHAMCS are not simple random samples

 Clustering effects of visits within the physician’s practice, physician practices within

PSUs, clinics within hospitals

 Must use some method to calculate standard errors for frequencies, percents, and rates

27

Ways to Improve Reliability of Estimates

 Combine NAMCS, ED and OPD data to produce ambulatory care visit estimates

 Combine multiple years of data

 Aggregate categories of interest into broader groups.

28

NAMCS vs. NHAMCS

 Consider what types of settings are best for a particular analysis

– Persons of color are more likely to visit OPD's and ED's than physician offices

– Persons in some age groups make disproportionately larger shares of visits to

ED's than offices and OPD's

29

File Structure

Download data and layout from website http://www.cdc.gov/nchs/about/major/ahcd/a hcd1.htm

Flat ASCII files for each setting and year

NAMCS: 1973-2002

NHAMCS: 1992-2002

30

Trend considerations

Variables routinely rotate on and off survey

Be careful about trending diagnosis prior to

1979 because of ICDA (based on ICD-8)

Even after 1980- be careful about changes in ICD-9-CM

Number of medications varies over years

1980-81 – 8 medications

1985, 1989-94 – 5 medications

1995-2002 – 6 medications

2003+ – 8 medications

Diagnostic & therapeutic checkboxes vary

Use spreadsheet for significance of trends

31

Example

Hypothesis -Educational Efforts Targeted at Judicious Antibiotic Use Will Reduce

Prescription Rates in all Treatment Settings

32

Study Design

Retrospective collection of data from

– NAMCS

– NHAMCS

1994-2000 study years

Antibiotic prescribing patterns and diagnoses

Children <5 years of age

Clinic type -- Pediatric

Physician type – Pediatrician or Family Medicine

33

Data Stratification

Race –

White, Black and other

Time period –

94 & 95, 96 & 97, 98 & 00

Antibiotics –

Penicillin's, Cephalosporins,

Erythromycin/lincosamide/macrolides,Tetracyclines,

Chloramphenicol derivatives, Aminoglycosides,

Sulfonamides and trimethoprim, Miscellaneous antibacterial agents, and Quinolone/derivatives

 Diagnoses -- Otitis media, Sinusitis,

Pharyngitis,Bronchitis,Upper respiratory tract infection (URI)

34

Overall Antibiotic Rates in Children

<5 Based on Source of Care

2000

1500

1000

500

0

1994 1995 1996 1997 1998 1999 2000

Years

Hospital-based ED Office-based

35

Total Care Years White Black Rate

Ratio

95% CI

Visit rates per 1000 children aged <5 years

1994-

1995

1996-

1997

4150 3102 1.34

1.22,

1.47*

4529 4320 1.05

1.02,

1.08*

1998-

2000

4204 4302 0.98

0.70,

1.34

36

White children Black Children

100%

80%

60%

40%

20%

0%

199419961999-

1995 1998 2000

Years

199419961999-

1995 1998 2000

Hospital-based

ED

Office-based

37

Total Care

Antibiotic prescription rates per

1000 children aged <5 years

Years White Black Rate

Ratio

1994-

1995

1996-

1997

1998-

2000

1494 998

1421

1118

1320

1074

95% CI

1.50

1.48,

1.51*

1.08

1.04

0.96,

1.22

0.86,

1.24

38

Total Care Years White Black

1994-

1995

816 520

Rate

Ratio

1.57

95% CI

1.46,

1.69*

Otitis media rates per

1000 children aged <5 years

1996-

1997

1998-

2000

779

630

739

603

1.06

1.05

1.04,

1.07*

0.69,

1.58

39

Results

 Decline in antibiotic prescribing in children <5 years; most notable in office-based and emergency department settings

 Penicillin's were common antibiotics used

 Most common diagnosis in all three settings was otitis media

Natasha B. Halasa, Marie R. Griffin, Yuwei Zhu, and Kathryn M.

Edwards. Difference in antibiotic prescribing patterns for children aged less than five years in the three major outpatient settings, Journal of

Pediatrics. 2004; 144:200-205

40

Code to create design variables: survey years 2001 & earlier

CPSUM=PSUM;

CSTRATM = STRATM;

IF CPSUM IN(1, 2, 3, 4) THEN DO;

CPSUM = PROVIDER +100000;

CSTRATM = (STRATM*100000)

+(1000*(MOD(YEAR,100))) + (SUBFILE*100) +

PROSTRAT;

END;

ELSE CSTRATM = (STRATM*100000);

41

SUDAAN version 8.0.2 example

proc crosstab data=test1 design=WOR filetype=sas;

Nest stratm psum subfile prostrat year provider dept su clinic/missunit;

Totcnt poppsum _zero_ _zero_ _zero_ popprovm _zero_ popsum _zero_ popvism;

Weight patwt;

Tables sex*ager; run ;

42

SUDAAN version 8.0.2 example

proc crosstab data=test1 filetype=sas;

Nest stratm psum ;

Weight patwt;

Tables sex*ager; run ;

43

STATA version 8. example

Use http:// ***/test1 svyset [pweight=patwt], strata(cstratm) psu(cpsum) svytab sex ager svymean age

44

SAS version 9.1 example

proc surveyfreq data=test1; tables sex*ager; strata cstratm; cluster cpsum; weight patwt; run ;

45

Some considerations: SUDAAN vs.

SAS Proc Surveymeans

SUDAAN

•design variables=cstratm, cpsum (1-stage design)

PROC Surveymeans

•design variables=cstratm, cpsum (1-stage design)

• nest=cstratm, cpsum • strata cstratm

• cluster cpsum

• Sort by design variables • Sort not needed

• Weight data: Patwt • Weight data: Patwt

• Subgroup=identify categorical variables variables

• Tables=analysis variables • Var=analysis variables

46

If nothing else, remember…The Public

Use Data File Documentation is

YOUR FRIEND!

 Each booklet includes:

– A description of the survey

– Record format

– Marginal data (summaries)

– Various definitions

– Reason for Visit classification codes

– Medication & generic names

– Therapeutic classes

47

Other Public Domain Data

CDC WONDER -http://wonder.cdc.gov/

National Center for Health Statistics -http://www.cdc.gov/nchs/

 National Health and Nutrition Examination

Survey (NHANES) -http://www.cdc.gov/nchs/nhanes.htm

 National Health Interview Survey (NHIS) -http://www.cdc.gov/nchs/nhis.htm

National Survey of Family Growth (NSFG) -http://www.cdc.gov/nchs/nsfg.htm

Census -http://www.census.gov/

48

Other Public Domain Data (cont.)

Dept. of Health, TN http://hitspot.state.tn.us/hitspot/hit/main/

SPOT/frames/SPOT/index.htm

49

Thanks

 Natasha Halasha

 Susan Schappert -

National Center for

Health Statistics

 Linda McCaig & David Woodwell -

National Center for Health Statistics

50

Questions?

51

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