Dr. Erin Friedman
Office: G41 Wilson Hall
Phone: 919-962-2436
E-mail: efriedman@unc.edu
Teaching Assistants
Dr. Jason Reed
Marybeth Anderson marybeth_anderson@med.unc.edu
Thomas Lane trlane@email.unc.edu
Course Hours
Office: 305 Coker Hall
Phone: 919-962-5699
E-mail: jreed@email.unc.edu
Lecture: 201 Coker Hall, M, W, F 11:00-11:50 am
Recitation: M 3:00, 4:00, 5:00, Tu 2:00, W 1:00, 2:00, Th 2:00, 5:00 pm
Dr. Friedman’s Office Hours (beginning Monday 1/7)
Monday 12:30 - 2:00 pm and Wednesday 10:00 - 11:00 am
Prerequisites
Passing grades in Biol 101 and Biol 202
Course Goals / Learning Objectives
This course is an introduction to the methods and knowledge of Cell and Developmental
Biology. In the first part of the course, you will learn the components of cells, how they are made, and how they work together to carry out cellular functions. In the second part of the course, you will learn how cells differentiate, acquire distinct fates, and coordinate their activities to form a functioning organism. Throughout the course, you will learn about methods that are used to advance our knowledge in these areas and the general principles that emerge from their study. You will be asked both to learn what happens and how we know what happens; i.e.
, you will be responsible for the content and the process of science.
Textbook
Essential Cell Biology , 3 rd edition, Alberts et al.
and Principles of Development , 4 th Edition,
Wolpert et al.
Course Website http://sakai.unc.edu
For general announcements and assignments, visit the Sakai lecture site. Class slides will be posted on Sakai in the Resources section no later than the day before the lecture.
Posted lectures may differ slightly from the version that is presented in class. Recitation homework assignments can be found in the Resources section, and online lecture homework assignments will be posted in the Tests & Quizzes section.

Grading
Exams : You will take 4 exams in this course, and each exam is worth 22.5% of your final grade. These exams will cover material from the textbook, lecture, and recitation. All students are expected to take all exams when they are scheduled. Students with special circumstances ( i.e., medical or family emergency documented in writing) who are unable to take an exam must request permission to take a make-up exam (possibly an oral exam). Students are expected to notify the instructor prior to missing an exam and to assume responsibility for scheduling a make-up exam in a timely manner.
Online lecture homework assignments : These daily assignments will test your comprehension of the textbook reading material that is assigned before each lecture and will comprise 5% of your final grade. The assignments will be posted on Sakai and must be completed by 10 am on the due date. NO LATE WORK will be accepted for any reason. The assignments will be available to you in advance, so there is no excuse for not completing them on time. Up until the due date, you may repeat the assignments as many times as you would like; Sakai will save your highest score. The first homework assignment will be due on Fri 11 January (Lecture 2).
Recitation homework assignments : These assignments will be graded for completion on an all-or-none basis. Collectively, they are worth 5% of your final course grade. They will be turned in to your TA at the beginning of the recitation section. No late homework assignments will be accepted.
Regrades: If, for some reason, you feel an error has been made in determining an exam score, you may submit the exam for a re-grade within 3 school days after the exam has been returned to the class. You must submit in writing your reasons for requesting a regrade. Staple the request to your exam, and give it to the appropriate instructor or TA.
Legitimate reasons for a re-grade request include, for example, incorrect summation of scores and bona fide errors in grading a particular problem; this does not include student judgments about the amount of partial credit deserved for incorrect answers . Written responses to student requests will be returned in class. To submit a regrade request, your exam must have been taken in ink.
Participation and Attendance
I cannot make you come to class or recitation, pay attention, or discuss Biology with your classmates outside of class. However, because this is your education, it behooves you to do all of these things. I will try to help guide your discussions by asking questions throughout the lecture and allowing you to respond. You will be using a program called
PollEverywhere.com through your laptop or mobile phone. See Sakai for the required registration information.
Recitation
Although I encourage you to ask questions during the lecture, I understand that it is difficult to accommodate in such a large class, and you will not always think of questions during the 50-min lecture period. Therefore, your TAs are here to allow you to ask questions and hold discussions in a smaller group setting. Recitation is not a review session; your TAs will not re-lecture material during this time. However, they will review your homework assignments and exams, they will lead discussions and activities, and they will answer any questions you may have about the lecture material. Please come to recitation prepared to ask questions; you can only get out of recitation what you put in.

You will also hand in your weekly problem sets in recitation; these will be graded by your
TAs for completion (see grading section).
Resources and Getting Help
Textbooks: In addition to the assigned readings, I have provided a link on Sakai to an online version of an old edition of the textbook Developmental Biology (Gilbert); a new edition of this textbook is used by some other Biol 205 sections, and the online edition may be useful to some students. A copy of Principles of Development by Wolpert et al.
is on reserve in the undergraduate library.
Office Hours: I am available during my office hours in Wilson Hall every week and by appointment if necessary.
Discussion Board: The Sakai discussion board (see Discussion and Private Messages section) will be available for you to ask and answer questions. Because of the large number of students in this course, questions about course content and organization that I receive via email will be reposted anonymously on Sakai so that all of the students can see the answers to questions that other students have asked. If you post your question directly to Sakai, it will be answered more quickly than if you ask me or the TAs via e-mail.
Students are encouraged to post their own answers to questions posed by other students, and the TAs and I will moderate and correct answers as needed.
Review Sessions : The lecture schedule includes a “catch-up” day before each exam. This class period will be used to wrap up any material that we haven’t yet covered and to answer your exam questions.
Peer Tutoring : Please see the following schedule for departmental peer tutoring availability http://bio.unc.edu/undergraduate/course-info/tutoring/
Honor Code
As in all classes at UNC-CH, the UNC Honor Code ( http://honor.unc.edu/honor/index.html
) is in effect in this class. Although you are encouraged to discuss homework questions with one another, all submitted homework must be your own work . All in-class exams and quizzes are to be taken without assistance (including books, notes, and other people), and you must sign your pledge to that effect. Academic dishonestly will not be tolerated.
The professor reserves to right to make changes to this syllabus, including homework due dates and test dates (excluding the officially scheduled final examination) when unforeseen circumstances occur. These changes will be announced as early as possible so that students can adjust their schedules.

Date
W Jan 9
F Jan 11
M Jan 14
W Jan 16
F Jan 18
M Jan 21
W Jan 23
F Jan 25
M Jan 28
W Jan 30
F Feb 1
M Feb 4
W Feb 6
F Feb 8
M Feb 11
W Feb 13
F Feb 15
M Feb 18
W Feb 20
F Feb 22
M Feb 25
W Feb 27
9
10
12
13
14
15
16
17
Lecture
1
2
3
4
5
6
7
8
11
Lecture Schedule
Topic
Introduction to Cell Biology and
Development
How to Study Cells
Gene Expression (Reed)
Proteins
Lipids and Membranes
Holiday – No class
Membrane Transport
Intracellular Compartments and
Transport I
Intracellular Compartments and
Transport II
Catch-up and review
Exam I (Covers lectures 1-8)
Mitochondria
Chloroplasts and Origin of Organelles
Cytoskeleton: Actin and Cell
Contractility
Cytoskeleton: Intermediate Filaments
Cytoskeleton: Microtubules
Cell Cycle and Cell Death
Mitosis and Meiosis I
Mitosis and Meiosis II
Meiosis and Fertilization (Reed)
Catch-up and Review
Exam II (Covers lectures 9-17)
Readings (W=Wolpert,
A=Alberts)
A: Chapter 1
W: 1-32
A: Chapter 1
W: 365-375, 115;
A: 329-333, 350-353
A: Chapters 2 and 4
A: Chapter 11
A: Chapter 12
A: Chapter 15
A: Chapter 15
A: Chapter 14 (453-476)
A: Chapter 14 (476-491)
A: Chapter 17
A: Chapter 17
A: Chapter 17
A: Chapter 18
A: Chapter 19
A: Chapter 19
W: 335-348

Recitation Schedule
Date
Jan 7-10
Jan 14-17
Jan 21-24
Jan 28-31
Feb 4-7
Feb 11-14
Feb 18-21
Topic
No recitation this week
Lectures 1-2
Discussion: Antibodies and How to Study
Proteins
Tues-Thurs only*
Lectures 3-5
Lectures 6-7
Activity: TBA
No recitation this week
Lectures 9-11
Activity: TBA
Lectures 12-14
Activity: TBA
Homework Assignment
N/A
HW 1
Read panels 4-3, 4-4, and 4-5
HW2
HW 3
N/A
HW 4
HW 5
Feb 25-28 Monday and Tuesday ONLY*
Lectures 15-17
HW 6
*On these weeks, if your recitation section does not meet, you may attend another scheduled recitation (and submit your homework at that time). If you choose not to exercise this option, you must submit your weekly homework during lecture on Wednesday of that week . Failure to do so will result in no credit for the assignment.