Michael D. Weaver, DO Physical Medicine & Rehabilitation Sports Medicine October 16, 2013 Become familiar with the basic anatomy of the wrist and causes of carpal tunnel syndrome {CTS}. Obtain a better understanding of the signs and symptoms associated with CTS. Become familiar with some of the various testing and treatments for CTS. Entrapment of the median nerve at the carpal tunnel is the most common and best characterized peripheral compression neuropathy › Prevalence: 2% Male & 3% Female 0.1% to 10% of the population Higher rates reported in those individuals involved in repetitive wrist motion activities No concrete data supporting cumulative trauma › 50% of patients have bilateral CTS ~38% are asymptomatic in ‘uninvolved’ hand Likely play a role by either increasing pressure within the CT or increasing susceptibility of the median nerve to pressure, however CTS is largely idiopathic › Normal – 2.5mm Hg (neutral) › CTS – 32mm Hg increased to 94-110mm Hg with wrist flexion/extension Neuronal changes in < 2 hours Contributing Factors: › Pregnancy, thyroid disorders, chronic kidney disease, acromegaly, diabetes, obesity, smoking, alcohol abuse, inflammatory arthritis, genetics Chronic compression of nerve inhibits axonal transport and epidural blood flow which results in intraneural edema, myelin thinning, nerve fiber degeneration and fibrosis. › Impaired nerve circulation › Diminished nerve elasticity › Decreased nerve gliding Median nerve travels beneath transverse carpal ligament along with 9 tendons › Flexor Digitorum Profundus {FDP} – 4 › Flexor Digitorum Superficialis {FDS} – 4 › Flexor Pollicis Longus {FPL} Provides motor and sensory input to a portion of the hand Clinical Features › Pain, numbness, tingling in digits I-III › Sparing of sensation to thenar eminence {palm} Palmar cutaneous sensory branch › More commonly c/o entire hand and vague complaints of pain in the shoulder and sharp shooting pains up the forearm 50% of patients reliably localize Neck pain is NOT an associated symptom Usually worsen at night and can awaken patients from sleep › + flick sign Exacerbated when driving or talking on the phone Frequently dropping objects, weak grip Fatigues with repetitive activity Visual Inspection › Asymmetry › Skin Changes Strength Sensation › Light touch/Pinprick › Vibration › 2 point discrimination Provocative Maneuvers Tinel’s sign Phalen Maneuver › Reverse Phalen Carpal Compression › Durkan’s Pronator Syndrome › Compression of the median nerve as it passes through the pronator teres muscle at the elbow Double Crush Syndrome › Concomitant involvement of a pinched cervical nerve root in the neck C6 and C7 › Thorough history and physical examination Truly a clinical diagnosis Constellation of symptoms Use of diagnostic tools › Ultrasound › Electrodiagnostic Studies Noninvasive Allow for real-time visualization of nerve Assist in guided injections Nerve Conduction Studies Electromyography Conservative › › › › › › Activity modification Wrist splints Corticosteroid injection US therapy Nerve gliding Medications Vitamin B6 NSAIDs v oral steroids Surgical › Open v Endoscopic carpal tunnel release {CTR} University of Louisville Physicians › Physical Medicine & Rehabilitation › Frazier Rehab Institute & Neuroscience Center › 502.584.3377