YORK UNIVERSITY
Department of Biology
Faculty of Science and
Engineering
Course outline
Immunobiology
(SC/BIOL 3120 3.0)
W2011
Prerequisites:
SC/BIOL2020 4.0; SC/BIOL2021 4.0
1
Welcome to BIOL3120!
SC/BIOL3120 3.0
Prerequisites:
SC/BIOL2020 4.0; SC/BIOL2021 4.0
Objectives:
The course is designed to provide students with a sound,
comprehensive understanding of the immune system, including the Biology
and
Chemistry
of
immune
responses.
Topics
will
include
anatomy/development of the immune system, structure and function of
antibodies, T cell receptors, antigen receptor diversity, cellular interactions,
and immunological responses in disease such as Cancer.
2
Instructor: Dr. Michael Scheid
Rm. 236 Farqharson Building
Website: www.yorku.ca/mscheid
E-mail: through WebCT only please
Course timetable:
Tuesdays 11:30 am – 1:00 pm SLH F
Thursdays 11:30 am – 1:00pm CSE A
Office hours:
Friday 9:30-11:00 am
3
TEXTBOOK:
The Immune System, Third Edition. Garland Science
Author: Peter Parham
Required
Available at the York University Bookstore
Two copies are available at the Stacie Library reserve desk
4
COURSE Web Site: WebCT
A York WebCT account is required to access
online course material.
Information about WebCT at York can be found at:
www.yorku.ca/fsc/webct/student/quickstart.htm
• WebCT is the online resource for this course.
It will be used for private mail to the instructor or
to the TA, for accessing your grades, and for
other course-related resources.
• Midterm examination grades will be posted when
they become available. Please do not email the
instructor nor the TA asking when grades will be
posted.
• The Midterms will not be returned but will be available
for viewing during office hours.
5
STUDENT EVALUATION:
There will be TWO Midterm exams, each worth 25% of your grade:
Midterm 1 – February 3
Midterm 2 – March 10
Final Exam : 50%
[Date to be announced by registrar. Cumulative]
[If an evaluation is not completed, a “0%” grade
will be earned for that evaluation]
Please note:
1. Exam questions will be derived from lectures, lecture material
and the text book.
2. Midterm exams will be multiple choice and true/false.
3. Final exam will be a combination of multiple choice, short answer, and
long answer questions.
6
Please note :
There will be NO MAKE-UP of the midterm exams.
For medical issues please have your physician fill out the Attending
Physician Statement. This form is available from the Registrars website.
7
Academic Integrity: Senate Policy on Academic Dishonesty
Students are expected to be familiar with and follow
York University’s Policies regarding academic integrity.
Please consult the website below for more details:
http://www.yorku.ca/academicintegrity/students.htm
8
• ACADEMIC MISCONDUCT WILL NOT BE TOLERATED.
• Cheating is the attempt to gain an improper advantage in an academic evaluation. Forms
of cheating include:
– Obtaining a copy of an examination before it is officially available or learning an
examination question before it is officially available;
– Copying another person’s answer to an examination question;
– Consulting an unauthorized source during an examination;
– Obtaining assistance by means of documentary, electronic or other aids which
are not approved by the instructor;
– Changing a score or a record of an examination result;
– Submitting the work one has done for one class or project to a second class,
or as a second project, without the prior informed consent of the relevant instructors;
– Submitting work prepared in collaboration with another or other member(s) of a
class, when collaborative work on a project has not been authorized by the instructor;
– Submitting work prepared in whole or in part by another person and representing
that work as one’s own;
– Offering for sale essays or other assignments, in whole or in part, with the
expectation that these works will be submitted by a student for appraisal;
– Preparing work in whole or in part, with the expectation that this work
will be submitted by a student for appraisal.
9
For Thursday please read:
Chapter 1 Elements of the Immune System
Chapter 2 Innate Immunity
10
Why do we study Immunology?
11
12
From the following article:
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
Jean-Pierre Hugot et al.
Nature 411, 599-603(31 May 2001)
13
From the following article:
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
Jean-Pierre Hugot et al.,
Nature 411, 599-603(31 May 2001)
14
15
From the following article:
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
Yasunori Ogura, et al.,
Nature 411, 603-606(31 May 2001)
16
From the following article:
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
Yasunori Ogura, et al.,
Nature 411, 603-606(31 May 2001)
17
18
19
20