This is a Foldable * Use 4 sheets of paper. It should look like this.. (Next slide) How to make a flip book.. • • • • • • • • • • • • • • • LAYERED-LOOK BOOK Collect 4 sheets of paper and layer them about 1.5 cm apart vertically. Keep the edges even. Fold up the bottom edges of the paper to form 8 equal tabs. Fold the papers and crease well to hold the tabs in place. Staple along the fold. Label each tab. Tabs for Foldable • Title= Plasma membrane • Functions of Cell mbn • Fluid mosaic model – Phospolipid – Bilayer – Layer structure – Mbn structure • Proteins Cell Membrane & Function FYI: The Plasma Membrane • The Plasma Membrane Isolates the Cell While allowing communication with its surroundings. 3 Major General Functions. 1. Isolates internal environment (cytoplasm) from external environment. 2. Regulates exchange of essential substances. 3. Communicates with other cells. Plasma Membrane • Membrane function is dependent on membrane structure. Fluid Mosaic Model • The Membranes are “Fluid Mosaics” – Proteins Move Within Layers of Lipids. • Phospholipids are “grout” & membrane proteins, are the “tiles”. • FYI: Fluid Mosaic Model was developed in 1972 by S. J. Singer and G. L. Nicholson Phospholipids- draw this!! • Phospholipids have a polar “head” and two nonpolar “tails” • Double bonds in the tail increase fluidity of membrane The Bilayer. • Amphipathic • The tails point in toward each other, and the heads point toward the outside, or inside of the cell. • Polar heads form hydrogen bonds with water; • Hydrophobic interactions keep tails facing each other. Look at What Happens!!(You don’t write this down) • Phospholipid bilayer selectively isolates internal environment from external environment • Most biological molecules are hydrophilic and cannot easily pass through the membrane • Some very small molecules or uncharged, lipid-soluble molecules can freely pass through membrane The Phospholipid Bilayer Is the Fluid Portion of the Membrane Phospholipid Bilayer Structure • Cholesterol in animal cell membranes makes the bilayer stronger. – more flexible, less fluid, and less permeable to water-soluble substances. • Flexibility and fluidity is very important to the function. Membrane Structure All of the following can be found in the mbn: – Phospholipids – Cholesterol – Proteins • regulate the movement of substances across the membrane • communicate with the environment. Types of Proteins • Transmembrane Proteins (Integral) – Transport proteins – receptor proteins – recognition proteins • Glycoprotein- have a carbohydrate group attached. • Peripheral proteins- attached to the cytoskeleton Let’s Review !!