Menopause Medically “untreated” woman Medically “treated” woman The medical view of Menopause is that is a deficiency disease. Menopause is listed in the MIMS Disease Index on page 303: “The menopause occurs when women run out of viable ova or have their ovaries removed or damaged at surgery. In either case, the production of oestrogen, progesterone and androgens from the ovary is reduced below the level necessary to maintain good cellular responses. In those women who pass the menopause and enter a sex hormone deficient state, the ensuing problems can be numerous and include both short and long-term cellular malfunction. Long-term dysfunction ultimately leads to profound and irreversible damage to the total organism In Australia, there are about 2,300.000 women who are postmenopausal, with about 80,000 new cases occurring every year. It is by far the most common hormone deficient condition in the world and is the one which up till now has been treated least effectively by the medical profession or else ignored as being a ‘natural event’”. This ‘lamentable condition’, menopause, which ‘afflicts’ women in great numbers, is treated by medicos using oestrogen and progestogens. “Natural therapists view menopause as a normal transition. Menarche, menstruation and menopause are seen as normal phases which effect women in their passage through life, and which may need supportive treatment. Rather than encouraging mid-life women to believe they have a disease, most natural therapists (and many like-minded doctors) encourage menopausal women to adopt positive lifestyle changes, good eating patterns and a positive attitude to this phase. Researchers in one study found that the well being of midlife women was related to being physically well, exercising moderately, having a positive attitude to menopause and feeling happy. Exercising, even once per week, was associated with fewer symptoms, as were positive relationships and friendships. Hormonal status was not the relevant feature of a positive menopausal experience” (Trickey 1998:134, 135). MENOPAUSE General Information Definition: The cessation of the menstrual cycle in women, normally between the age of 48 and 52 years. Some women have been known to enter menopause in their twenties and thirties due to hormonal irregularities. Also a woman, who has had a surgical procedure where the ovaries have been removed, will also enter her menopausal phase. The length of this hormonal change is very dependent on the woman’s physiology and fertility pattern. Variables such as race, hereditary, health status, diet and level of physical activity may influence the way each woman experiences menopause. The total number of follicles and eggs in a woman’s body decrease throughout her life due to ovulation and atresia. As the female approaches menopause, the number of follicles further decreases, causing a decrease in the amount of ovarian oestrogen produced. The lowered oestrogen levels are not sufficient to signal the brain to stop producing FSH and so FSH (levels normally >100U/l) continues to be released causing rapid and inadequate follicular development. With fewer and fewer follicles remaining, oestrogen production continues to drop. Insufficient oestrogen is produced regularly to induce the LH surge necessary for ovulation. As ovulation ceases completely, the levels of both FSH and LH rise significantly. A postmenopausal woman is not without oestrogen completely,. Oestrogen levels in her body can no longer support the fertility cycle but they are adequate for the maintenance and support of tissues. The type of oestrogen changes in postmenopausal women to estrone whereas pre menopausal oestrogen is mainly oestradiol. Signs & Symptoms Hot flushes Hot flashes are a normal bodily change associated with the transition between the menstrual years and menopause. Hot flushes can be a great way for the body to cleanse itself. Thinner women are more likely to experience hot flushes than their larger counterparts due to the rapid depletion of oestrogen (due to reduced fat stores of oestrogen in the body) Ovaries no longer respond to FSH from the pituitary. The result is that the hypothalamus raises its production of GnRH and its “voltage”. Finally the electric excitation spills over to affect an adjacent limbic nucleus involved in temperature control, causing a reaction, which produces rapid temperature changes in the body. The capillaries are affected by consequent chemical or hormonal changes, which take place in the tissues causing them to dilate and the nerves to be highly reactive. In most women hot flushes are at their most intense during the last year or so before menstruation ceases and during the first year or so afterwards 75% of women will experience some degree of hot flushes. In Indonesia and Japan, women experience very few hot flushes, compared to women in Western societies. They have a diet high in plant sterols with high levels of oestriol – the good guy oestrogen that is very protective. HRT does not “cure” hot flushes – it merely delays the inevitable Contributing factors to hot flushes –cigarette smoking, allergies, caffeine, hot spicy food, untreated diabetes Difficulty breathing Irritability Fatigue, vertigo, general decline in physical and mental ability Anxiety Nervousness, mood changes, depression without reason Osteoporosis Insomnia Palpitations Vaginal dryness Poor memory and concentration Muscle and joint aches backaches, breast tenderness Formication Headaches Increased urination and dysuria Hirsutism Obesity, nausea and bleeding Dry and rapid aging of skin Loss of libido or increased libido EFFECTS OF PROGESTERONE Increases libido Prevents cancer of the womb Protects against fibrocystic breast disease Helps protect against breast cancer Maintains the lining of the uterus Stimulates the building of new bone Strengthens skin Is a natural diuretic Anti-depressant Encourages fat burning and the use of stored energy Normalises blood clotting Concerned with procreation and survival of the foetus Precursor to important stress hormones EFFECTS OF OESTROGEN Decreases libido Increases risk of womb cancer Stimulates breast cell activity Increases risk of breast cancer Proliferates the lining of the uterus Slows down the resorption of old bone Thins skin Encourages salt and water retention Can produce headaches and depression Lays down fat stores Increases blood clotting Concerned with the development and release of the egg End-molecule steroids Osteoporosis Definition: A generalised, progressive diminution in bone tissue mass per unit volume, causing skeletal weakness even though the ration of mineral to organic elements is unchanged in the remaining morphologically normal bone. Histologically there is a reduction in cortical thickness and in the number and size of trabeculae of cancellous bone, with normal width of osteoid seams. Bone resorption is increased; bone formation appears to be normal Note: Xrays f bone are normally useless as bone loss cannot be reliably picked up until there has been a change of up to 30%. A more accurate test is dual energy X-ray absorptiometry (DXA) where low dose X-rays are used of by using single photon absorptiometry where light is passed through the skin. The energy that is lost when photon beams pass through the body is then calculated by a machine to give an accurate reading of bone density. Signs and symptoms Severe backache Decrease in height Spontaneous fractures of the hip and vertebrae Osteoporosis is a disorder of calcium metabolism, not the absence of calcium. Black women have less bone loss than white women. Big women have less bone loss than small women. Overweight women have less bone loss than thin women. Meat eaters area at greater risk than vegetarians. People in third world countries whose dietary calcium intake is less than half our own have a very low incidence of this disease. Users of prescription drugs (methotrexate, corticosteroids, cimetidine) have a higher incidence of osteoporosis. Sedentary people have a higher incidence of this condition than those who obtain regular exercise. Taking high doses of calcium supplements can create unwanted kidney stones. The process of calcium absorption The absorption of calcium from water or mineral salts tends to be highly inefficient. Only somewhere between 20 and 30% of the calcium taken via processed foods will actually be absorbed. Most of it gets filtered via the kidneys and then excreted in sweat and urine. Weight bearing exercise can increase the rate of calcium absorption. The smaller the supply of calcium available from foods ant the greater the need, the body efficient calcium absorption becomes. When large quantities of calcium are available, the resorption of calcium is less. In the US where the consumption of calcium supplements and milk is the highest in the world, the incidence of osteoporosis is also the highest. Calcium needs an acid medium to be absorbed. Calcium needs Vitamin D to be absorbed, as well as parathyroid hormone, which regulates the level of calcium in the blood. An adequate supply of the right kind of fat also facilitates the absorption of calcium. Phosphorous in the diet is essential to build bone. Calcium to phosphorous ratio is 2.5:1. Taking drugs such as laxatives, diuretics, antacids and tetracyclines can impede calcium absorption. Coffee antagonises the absorption of calcium. Magnesium – need sufficient magnesium for calcium absorption. Excess meat protein in the diet will draw calcium out of bones, as the body attempts to neutralise the acidic protein waste products. Eskimos whose traditional diet was high in protein and high in calcium had the highest rate of osteoporosis of any group of people. By contrast the Bantu in Africa, who consume very little meat protein and less than 400 mg of calcium a day (often from plant sources)-remain totally free from osteoporosis. They also get plenty of exercise. Boron has also been implicated in the efficient absorption of calcium. Fluoridated water provides fluoride, which gives a new bone structure, which is of poor quality, highly brittle and makes bones more prone to breakage. General dietary recommendations Reduction of alcohol Eliminate smoking Adequate protein intake Elimination of the use of antacids that contain aluminium as they disrupt the normal calcium/phosphorous interaction Reduction of intake of processed meats and colas, which are high in phosphorous and leach calcium from bones Reduce refined foods. Diet has a direct influence on menopausal symptoms and is believed to contribute to the marked differences in symptoms experienced by women form other cultures, especially hot flushes. Changing dietary intake of various foods containing natural oestrogens (Phytooestrogens) reduces hot flushes and symptoms associated with vaginal dryness. Calcium rich foods Amount per cupful Spinach 300mg Bone makers Pak choy magnesium 200 mg Adequate Broccoli mg and trace elements Alfalfa and barley – high in175 minerals Chick peas 150 mg Boron Agar agar 400from mg food sources) Calcium in moderation (best Almonds Leafy green vegetables 300 mg Brazil nutsprotein diet 260 mg Moderate Tofu 100 mg Plant sterols – Soya based foods Cheese 200 mg per 25g Sea plants and green supplements – Spirulina, green algae Milk and chlorella 300 mg Silica Blackstrap molasses 140mg/tbsp Sunlight and vitamin D Spirulina 30mg/cup Vegetarian diet-balance to295 provid sufficient protein Non fat yoghurt Vitamin Tahini C 120mg per 14g Weight Kelp training 300 Whole grains Wholefoods Zinc Bone Breakers Processed convenience foods and junk fats Diuretics and antibiotics Crash dieting Deficiencies in minerals and trace elements Smoking Soft drinks including diet colas Salt Inadequate protein High saturated fat diet Sedentary lifestyle Coffee and alcohol Sugar Antacids which contain aluminium