FLORIDA STATE COLLEGE AT JACKSONVILLE COLLEGE CREDIT COURSE OUTLINE COURSE NUMBER: BCH 4024 COURSE TITLE: Introduction to Biochemistry and Molecular Biology PREREQUISITE(S): CHM 2211C (Organic Chemistry II with lab) with a grade of “C” or better COREQUISITE(S): None CREDIT HOURS: 4 CONTACT HOURS/WEEK: 4 CONTACT HOUR BREAKDOWN: Lecture/Discussion: 4 Laboratory: Other __________: FACULTY WORKLOAD POINTS: 4 STANDARDIZED CLASS SIZE ALLOCATION: 35 CATALOG COURSE DESCRIPTION: This course is a comprehensive one semester biochemistry course intended for science majors. Course topics to be covered include physical biochemistry, intermediary metabolism of key catabolic and anabolic pathways as well as the mechanisms for in vivo regulation of these pathways, a survey of molecular biology, and enzyme kinetics. Students will also learn about the structures and functions of proteins, nucleic acids, lipids and carbohydrates and how these biologically central molecules are synthesized and turned over. SUGGESTED TEXT(S): Berg, Tymoczko, and Stryer, Biochemistry, Freeman Publisher, Latest edition Mathews, van Holde, and Ahern, Biochemistry, Prentice Hall Publisher, Latest edition Voet and Voet, Biochemistry, Wiley Publisher, Latest edition 1 IMPLEMENTATION DATE: Fall Term, 2011 (20121) Proposal 2010-25 REVIEW OR MODIFICATION DATE: Fall Term, 2015 (20161) – Outline Review 14-15 2 COURSE TOPICS I. Chemical interactions in aqueous environments A. B. C. II. III. B. IV. B. V. B. 5 Structure 1. Fatty acids 2. Triglycerides and phospholipids Function 1. Biological membranes 2. Excitable membrane (action potentials) Survey of carbohydrates A. 6 Protein structure 1. Amino acids 2. Peptide bonds 3. Protein folding Protein function 1. Contractile proteins 2. Transport proteins Survey of lipids A. 4 Energy, heat and work Laws of Thermodynamics Chemical equilibria Free energy ATP Survey of proteins A. 4 Properties of water Acids/Bases Buffers Energetics A. B. C. D. E. CONTACT HOURS PER TOPIC 5 Structure 1. Simple sugars to oligosaccharides 2. Polysaccharides 3. Glycoproteins Function 1. Energy storage 2. Cell markers 3 COURSE TOPICS VI. Survey of Nucleic Acids A. B. C. VII. VIII. C. D. E. F. G. 6 Properties Vitamins and co-enzymes Basics of kinetics and catalysis Regulation Intermediary metabolism A. B. 6 Structure 1. DNA 2. RNA Function 1. DNA 2. RNA Regulation of gene expression Enzymes A. B. C. D. CONTACT HOURS PER TOPIC 24 Bioenergetics Carbohydrate metabolism 1. Catabolic pathways 2. Anabolic pathways Photosynthesis 1. Light reactions 2. Dark reactions Lipid metabolism 1. Catabolic pathways 2. Anabolic pathways Protein metabolism 1. Catabolic pathways 2. Anabolic pathways Metabolism of nitrogenous compounds 1. Catabolic pathways 2. Anabolic pathways Nucleic acid metabolism 1. Catabolic pathways 2. Anabolic pathways 4 Florida State College at Jacksonville Course Learning Outcomes and Assessment SECTION 1 Semester Credit Hours (Credit): Contact Hours (Workforce): Course Prefix and Number: BCH 4024 Course Title: Introduction to Biochemistry and Molecular Biology 4 SECTION 2a (To be completed for General Education courses only.) TYPE OF COURSE (Place an “X” in the box next to those that are applicable.) General Education Core (If selected, core discipline area will be identified in Section 4.) General Education (If selected, you must also complete Section 4, Section 5, and Section 8) SECTION 2b TYPE OF COURSE (Place an “X” in the box next to those that are applicable.) A.A. Elective A.S. Required Course A.S. Professional Elective X A.A.S. Required Course PSAV/Clock Hour/Workforce Upper Division/Bachelors A.A.S. Professional Elective Technical Certificate Development Education Apprenticeship Other: If selected, use this space to title “other” option. SECTION 3 INTELLECTUAL COMPETENCIES (Place an “X” in the box next to those that are applicable.) Reading Speaking Writing Listening X Critical Analysis Qualitative Skills Information Literacy Ethical Judgement X Scientific Method of Inquiry Working Collaboratively SECTION 4 (To be completed for General Education courses only.) GENERAL EDUCATION DISCIPLINE AREA (Place an “X” in the box next to those that are applicable.) Communications Humanities Mathematics Social and Behavioral Sciences Natural Sciences SECTION 5 (To be completed for General Education courses only.) GENERAL EDUCATION LEARNING OUTCOME AREA (Place an “X” in the box next to those that are applicable.) Communication Scientific and Quantitative Reasoning Critical Thinking Information Literacy Global Sociocultural Responsibility SECTION 6 LEARNING OUTCOMES Demonstrate knowledge of the structures and functions of proteins, nucleic acids, lipids, and carbohydrates TYPE OF OUTCOME (General Education, Course or Program) Course Demonstrate knowledge of biological membranes Course Demonstrate knowledge of the principles of enzymology Course METHOD OF ASSESSMENT Methods of assessment can include exams, quizzes, papers, lab reports and/or oral presentations Methods of assessment can include exams, quizzes, papers, lab reports and/or oral presentations Methods of assessment can include exams, quizzes, papers, lab reports and/or oral presentations 5 SECTION 6 LEARNING OUTCOMES TYPE OF OUTCOME (General Education, Course or Program) Demonstrate knowledge of bioenergetics of metabolism. Course Use basic scientific language and processes and be able to distinguish between scientific and non-scientific explanations. Discipline Demonstrate the application of interdisciplinary natural science curricula to biomedical sciences. Program METHOD OF ASSESSMENT Methods of assessment can include exams, quizzes, papers, lab reports and/or oral presentations. Students will answer a set of questions developed by the program faculty and delivered across courses in the discipline. A faculty panel will evaluate the answers a common rubric with scores from 1 (not yet competent) to 3 (competent). Students will answer a set of questions developed by the program faculty and delivered across courses in the discipline. A faculty panel will evaluate the answers a common rubric with scores from 1 (not yet competent) to 3 (competent). SECTION 7 Faculty name(s): Lourdes Norman Date: 01/20/2011 CS20150615 6