CURRICULUM VITAE Name: Date and place of birth : Nationality: Adderss: Mohammad Hassanzadeh-Khayyat 31/12/1948, Sabzevar, Iran Iranian Work: School of Pharmacy, Mashhad University of Medical Sciences, Mashhad 91775-1365, Iran Home: No 10, Khaghanie 1, Rezashahr,Mashhad, 91777, Iran Work: 0098(511) 8823255-66 Home: 0098(511) 8784762 Work: 0098(511) 8823251 Tel : Fax : E-mail: hassanzadeh_mk@yahoo.com hasanzadehm@mums.ac.ir ACADEMIC QUALIFICATIONS: B.Sc.: Chemistry 1969, Mashhad University ,Mashhad, Iran. M.Sc.: Analytical Chemistry 1974, Mashhad University, Mashhad, Iran. Chemistry(Analytical Instrumentation) 1975, University of London, U.K. Pharmacokinetics and Drug analysis, 1981, University of London, U.K. -Total of three years at U.S.A., - one year at Purdue University ( Indiana), 1986-87. and - two years at University of California, San-Francisco (UCSF), 1987-989. -Nine month at U.K. at Sheffield University, 2003-2004. M.Sc.: Ph.D.: Postdoctoral: AWARDS AND HONORS: Distinguwished Professor in seventh National Research Center of Medical Sciences (NRCMS)Festival, awarded by the Iranian President, Khatami, on January 2002. Winner of the prize for the best book of the year by 3rd Ferdowsi Research Festival, on December 2001. Selected as a seniour research man at the University of Mashhad Medical Sciences, on December 2000. Selected as a seniour research man at the University of Mashhad Medical Sciences, on December 2008. POSITIONS: 1975-1982 Instructor, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran 1982-1991 Assistant Professor, School of Pharmacy,Mashhad University of Medical Sciences, Mashhad, Iran 1991-1999 Associate Professor, School of Pharmacy,Mashhad University of Medical Sciences, Mashhad, Iran 1999-present Professor, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran 2004-2008 Head of Pharmaceutical Chemistry Department, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran 1995-1998 A member of University Research Council of the Mashhad University of Medical Sciences. 1999-2007 Editorial Board of Iranian Journal of Basic Medical Sciences. 2000-2002 A member of University Publication Council of the Mashhad University of Medical Sciences. 2002-2006 A member of Academic Promoutional Commitee of the Mashhad University of Medical Sciences. 2000-2002 A member of Special Committee for Academic Promoutional Commitee of the Mashhad University of Medical Sciences. 1983-2005 A member of University Publication Council of the Emam Resa University, Mashhad, Iran. 1982-2004 A member of Faculty Research Council of the School of Pharmacy, Mashhad University of Medical Sciences. 1985--2010 A member of Academic Promoutional Commitee of the School of Pharmacy, Mashhad University of Medical Sciences. 2002-2006 A member of higher education Committee of the School of Pharmacy, Mashhad University of Medical Sciences. 1975-1986 Director of Instrumental Analysis Lab. at School of Pharmacy, Mashhad University of Medical Sciences. 2000--present Director of Instrumental Analysis Lab. At Bu-Ali Reasearch Center, Mashhad University of Medical Sciences, Mashhad, Iran. 1990-2002 Director of Instrumental Analysis Lab., Organic and General Chemistry Lab., at School of Pharmacy, Mashhad University of Medical Sciences. 1990-2003 Director of Research Lab., at School of Pharmacy, Mashhad University of Medical Sciences. 2005- -2011 2005- -present A member of University Basic Sceinces Research Council of the Mashhad University of Medical Sciences. A member of University Publication Council of the Mashhad University of Medical Sciences. RESEARCH and ACADEMIC EXPERIENCES: Teaching Experiences: Biopharmacy and Pharmacokinetics Courses to Pharm. D., MSc (Toxicology), and Ph. D. Students.(Pharmaceutics, Biotechnology and Pharmacology Ph. D. Students) Instrumental Methods of Analysis Courses to Pharm. D., MSc (Toxicology), Ph. D. (Pharmaceutics) Students and also to Medical Physics Ph. D. Students. Quality Control Courses to Ph. D. (Pharmaceutics) Students. RESEARCH INTRESTS: -Drug bioavailability and bioequvalency. -Various aspects of drug analysis in vivo. -Drug analysis (TDM) and stability of drugs in vivo. -Drug analysis and stability of drugs in vitro. -Quantitative and qualitative evaluations of essentiol oils in various medicinal plants. - Evaluation of regional medicinal plants antioxidant activity. -Quantitative and qualitative evaluations of Pesticides in food materials. -Quantitative and qualitative evaluations of mycotoxins contamination in food materials. - Research in the area of Analytical Forensic Toxicology. SEMINARS & CONGRESSES: Taking part with presentation in more than 60 different international and national congresses and seminars in Iran and other countries. Supervising Thesis 1982--present Supervise and consultant of more than 15 different thesis of Ph.D. and MSc as well as supervising more than 80 different thesis of Pharm. D. students. Research projects Carried out at the school of Pharmacy Mashhad University of Medical Sciences (MUMS) 1- A computer program for calculating pharmacokinetics parameters. 2- Bioequvalency of different dosage forms of ampicillin in Iranian market. 3-Relative bioavailability of different brands of cephalexin capsules. 4- Comparative bioavailability studies of some oral amoxycillin capsules. 5-Acetylation phenotyping using isoniazid in Korasanian population. 6-Bioavailability study of four different oral formulation of cephradine capsules. 7- Phytochmical and antimicrobial studies of Iranian Conifers. 8- Study methods of bleaching beeswax. 9- Determination of Flouride in different kinds of domestic toothpastes and comparison with various foreign made commercial brands and international standards. 10- Determination of nicotine in differsent international and national kinds of cigaretts, cigar and tobacco. 11- Quantitative evaluation fluoride ion from different sodium fluoride tablet formulations in children. 12- Analysis of the Mentha piperita and Mentha pulegium essential oils and evaluation of their clinical effects on nasea and vomiting after chemotherapy. 13- Evaluation of antigout effect of some Iranian medicinal plants via xanthine oxidase activity inhibition and comparison with allopurinol. 14- Evaluation of urinary fluoride ion excretion after usig sodium fluoride mouthwash by children (7-11 year old ) and comparison with various foreign made commercial brands and international standards. 15- Study of preparation and purification of the anticancer, Taxul, from Taxus Baccata L. using tissue culture method. 16- Phytochemical study of trestrial plants of Hashilan wetland (Kermanshah province). 17- Phytochemical study of aquatic plants of Hashilan wetland(Kermanshah province). 18- Quantitative and qualitative studies on different cultivars of saffron in Iran. 19- The Antioxidant Activity of the Essential Olis of Iranian Cupressus semipervirens L. var. horizentaliss, Cupressus semipervirens L. var. cereinformis and Cupressus semipervirens L. var. fastigigiata DC. 20- The antioxidant activity of the methanolic extracts of Iranian commonConifers. 21- The Antioxidant Activity of the Essential Oils of Iranian Juniperus foetidissima and Juniperus sabina.. 22- Evaluation of Antioxidant Activity of the Essential Oils of Iranian Platycladus Orientalis and Pinus halpenisis using several quick and simple methods. 23- Evaluation of the genetic diversity and composition of essential oil of Iranian conifer spp. Based on RAPD and GCMS analysis 24- Inter individual Variability of Coumarin 7- hydroxylation in an Iranian population (Khorasan). 25- The Antioxidant Activity of the Essential Olis of Iranian Juniperus exelsa and Juniperus polycarpos.. 26- Extraction and structure elucidation of waxes in different species of Iranian conifers. 27- The Antioxidant Activity of the Essential Olis of Iranion Juniperus Oblonga and Juniperus ommunis subsp.hemispherica. 28- Determination of Aflatoxin M1 in pasteurizodn Milk samples in Mashhad. 29- Determination of heavy metals (Al, Pb, Cu, As) in dry and infusion black tea samples available in mashhad. 30- Comparison of sodium valproate clearance between epileptic patients and patients with acute mania. 31- Determination of mycotoxin patulin in apple juice produced in Mashhad. 32- Effects of pentoxyfylline on erythropoietin resistant anemia and Serum level of TNF- and INF- in renal failure patients. 33- Qualitative and quantitative determination of the volatile and aromatic compounds in various kind of traditional peppermint hydrola available in the Mashhad market. 34- Evaluation of antioxidant activity of methanol extracts of various kind of Artemisia (growing in Khorasan). 35- Evalution of enzymatic GSTs Genes polymorphisms and it's association with P16 methylation in Esophageal cancer patients. 36- Qualitative and Quantitative determination of monomer migration of polymeric containers in drink water packaging. 37- The Antioxidant Activity of the Essential Oils of different parts of Juniperus communis subsp.hemisphaerica in lipid system. 38- The Antioxidant Activity of the Essential Oils of different parts of Juniperus foetidissima and Juniperus sabina in lipid system. 39- Evaluation of Gancyclovir effect on mycophenolate mofetile clearance in kidney transplant patients. 40- Pharmacokinetic monitoring of vancomycin and evaluation of the affecting factors on vancomycin pharmarmacokinetics in hemodialysis patients. 41- The antioxidant activity of the essential oils and different extractions of Satureja horttensis and Artemisia dracunculus. 42- Evaluation of the genetic diversity and composition of essential oil of Iranian Ephedra spp. based on RAPD and GC-MS analysis. 43- Antioxidant activity of Iranian Cupressaceae essential oils in two different lipid systems. 44- Exposure assessment for mercury from consumption of marine fish in Iran. 45- Determination of Aldicarb, Bentazone, Molinate, Thiobencarb and Parathion in Mashhad pipe water and comparison with packed mineral water available in the markets. 46- Determination of Trace Heavy Metals Levels in Honey Samples from Mashhad city. 47- Extraction, purification and structure elucidation of sesquiterpene coumarins from the roots of Ferula flabelliloba and characterization of volatile components of the fruits by GC/MS. 48- Evaluation of gold nanoparticles effectiveness in sonodynamic and photothermal therapies in a Carcinoma tumor model (CT26). 49- DETERMINE NUTRITIONAL STATUS AND THE EFFECT OF ZINC SUPPLEMENTATION ON GROWTH AND BONE HEALTH IN PAEDIATRIC PATIENTS WITH THALASSEMIA. 50- Internal evaluation of medicinal chemistry group in Mashhad school of Pharmacy. 51- The antioxidant activity of the essential oils and different extractions of Satureja horttensis and Artemisia dracunculus. 52- Nutritional Status and Bone Health in Pediatric Patients with Transfusion-dependant β Thalassemia. 53- Evaluation of Antioxidant effects of various fractions from aerial parts of 3 species of Artemisia. 54- Study of binding pattern of G-CSF to proteins of Brain of mice. 56- Analyze of polymorphisms of paraoxonase,coagulation factor 13,platelet glycoprotein IIb,β2 adrenergic receptor and angiotensin II receptor genes in patients with stroke problem. 57- Extraction and analysis of diazinon in cucumber using its molecularly imprinted Polymer. PUBLICATIONS AND CONFERENCE PRESENTATIONS BOOKS 1-Biopharmacy and Drug Kinetics vol 1, 1992, Mashhad University of Medical Sciences Publication, Mashhad, Iran. 2-Instrumental Methods of Analysis, vol. 1, 2001, Mashhad University of Medical Sciences Publication, Mashhad, Iran, (Selected as the best book of the year by 3rd Ferdowsi Research Festival on December 2001). PAPERS 1) Franklin-Smyth, W., Hassanzadeh, M., (1976), A polarographic study of some Ncontaining organic compounds under aquarium conditions. Z. Anal. Chem., 280: 299-303. 2) Hassanzadeh, M.K. and Noormohammadi., A., (1986), Effects of food on pH and urinary rate of excretion of various drugs. Daru-Darman, 27, 46-51. 3)Yaghmai, S., Hassanzadeh-Khayat, M., (1987), Epicuticular wax alkanes of Cutellaria lateriflora L. Leaves. Iranian J. Chem., & Chem. Eng., (Oct.): 26-30. 4)Hassanzadeh, M. K., Aweek, F. T., WU, S., Jacobson, M. A. and Gambertoglio,J.G., (1990), Determination of phosphanoformic acid in human plasma and urine by high performance liquid chromatography with electrochemical detection. J. Chrom. Biomed. Appl., 525: 133-140. 5) Hassanzadeh, M.K., Yaghmaie, Sh., Amiri-Gheshlaghchai, A., (1990). Qualitative and quantitative evaluation of mefenamic acid in various dosage formulations in Iranian market, Daru-Darman, 86, 13-15. 6) Hassanzadeh. M.K., Yeghmaie, Sh., Farazmand, G., (1991) Quantitative and qualitative evaluation of cephalosporines in various dosage formulations in Iranian market, Daru–Darman, 84, 14-21. 7)Hassanzadeh, M. K., (1991) Quantitative evaluation of different dosage forms of ampicillin. Drug Dev. Ind. Pharm., 17(13): 1795-1810. 8) Hassanzadeh, M.K., Yeghmaie, Sh., Haramipore, H., (1992), Quantitative evaluation of amoxycillin in various dosage formulations in Iranian market, Daru-Darman, 102, 25-37. 9) Hall, S. D., Hassanzadeh-Khayyat, M., Knaller, M. P. and Mayer, P. R., (1992), Pulmonary investigation of 2-arylpropionic acids: Influence of protein binding. Chirality, 4: 349-352. 10) Hassanzadeh, M.K., Fazli-Bazzaz, B., and Shirazie, A., (1996), Relative bioavailability of cephalexin different brands of capsules. J. of Iran Univ .of Med. Sci (JIUMS), 3(1&2): 16-22. 11)Hassanzadeh, M.K., and Becket, A.H., (1997), Pharmacokinetic study of ketoprofen after oral administration of sustained release and non- sustained release dosage forms, Daru, 7(1): 73-85. 12) Hassanzadeh, M.K., (1997), Pharmacokinetics importance., J. of Khorasan Pharmaceutical Society, 2, 14-16. 13) Rahimizadeh, M., Hassanzadeh, M.K. and Haerizadeh, M, (1998), Alkaloids of Furmaria parvifora Lam, Fumariaceas, Oriental. J. of Chemistry, 14(2): 217-220. 14) Hassanzadeh, M.K., and Mayer, P.R., (1999), Disposition of Alpha -1-Antitrypsin in the isolated perfused rabbit lung. Daru, 7(2): 29-33. 15) Hassanzadeh, M.K., Mortazavi, A., Cohestanie, Gh., Bakhtiaryzadeh, K. and Akhavan, H., (1999). Quantitative evaluation of aflatoxine M1 in Pastorized milk in city of Mashhad., Iranian J. Basic Med. Sci., 2(1), 24-29. 16) Hassanzadeh, M.K., Rahimizadeh, M., Parsaie, H., (1999) Determination of total and free gossypol in variety of cottonseed grown in Khorasan and Golestan province using HPLC., J. of Sci., Ferdowsi University of Mashhad, (1), 7-11. 17) Hassanzadeh, M.K., Rahimizadeh, M. and Khoshrou, Z., (1999), Volatile constituents of Mentha piperita oil. ACGC Chem. Res. Commun., 8: 19-22. 18) Hassanzadeh, M.K. and Jalali, A. (1999), Study the amount of iodine in iodine-salt production in Khorasan., Iranian J. Basic Sci., 2(3), 146-151. 19) Hassanzadeh, M.K. and Moghimie, A., (1999), Population pharmacokinetics and clinical applications., J. of Razi, 11, 22-23. 20) Hassanzadeh, M.K., and Daneshvari, A., (1999), Comparative bioavailability studies of some oral amoxycillin capsules. Indian. J. Pharm. Sci., 61(1): 54-57. 21) Hassanzadeh, M.K., Khashayarmanesh, Z., Panahi, M., Mohammad-Esmaielie.D., and Mokrie, L.S., (1999), N-acetylation phenotyping using isoniazid in an Iranian and an Afghani population., Indian J. Pharm. Sci., 61(50): 297-300. 22) Hassanzadeh, M.K., Rahimizadeh, M., Haririzadeh, G, and Atefi, A.A., (1999), New taxanes from Taxus baccata L., Iranian. J. of Sci. & Tech., 23(4): 313-319. 23) Hassanzadeh, M.K.,Fazli- Bazzaz. B., Afzali, S., (1999) Comparative bioavailability of four oral formulation of cephradine capsules. Daru, 7(4): 15-18. 24) Hassenzadeh, M.K., Rahimi, M.N. (1999) Comparative bioavailability of a new sustained release indomethacin tablet formulation. Indian Drugs, 36 (4): 253-255. 25) Hassanzadeh, M.K., Daneshvari, E., (2000) Rapid determination of amoxycillin in plasma and urine samples by high performance liquid chromatography. Iranian J. Basic Med. Sci., 2(4): 5-9. 26) Hassanzadeh, M.K., Rahimizadeh, M. and Vaheddie, L., (2000) Constituents of the essential oils of aerial parts of dill (Anethum graveolens L.) herb. Oriental J. of Chemistry, 16(1): 29-32. 27) Hassanzadeh, M.K., Rahimizadeh, M., Reisner, L.A., Gambertoglio, J.G., (2000) A liquid chromatography assay of sodium levothyroxince in commercial preparations using an internal standard. ACGC Chem. Res. Commun., 12: 1-7. 28) Hassanzadeh, M.K., Ramazanie, M., Golmohamadzadeh, S. (2000), Volatile constituents of Nigella sativa L. seeds. Oriental J. of Chemistry, 16(3): 461-462. 29) Hassanzadeh, M.K. and Moghimie, A., (2001) Effects of excersize on drug metabolism, J. of Razi, 11, 22-23. 30) Hassanzadeh, M. K., Rahimizadeh, M., Fazli- Bazzaz. B., Emami, S. A., Assili, J., (2001) Chemical and Antimicrobial Studies of Platycladus orientalis Essential Oils. Pharmaceutical Biology, 39(5), 388-390. 31) Rahimizadeh, M., M., Hassanzadeh, M. K., Danesh, N. M., (2001) Analysis of Iranian Artemisia absinthum L. essential oil. ACGC Chem. Communications., 13, 33-36. 32) Makarem, A., Hassanzadeh, M.K., Orafaie, H., Mazhari, F., (2001), A comparative study on the level of Fluoride absorption rate between a locally produced and an standard fluoride tablet. Beheshti Univ. Dent. J., 18(4): 339-346. 33) Hassanzadeh, M.K., Rahimizadeh, M., Khoshrou, Z., (2002) Volatile constituents of Mentha viridus L. oil. J. of Sciences of Ferdowsi University of Mashhad, 3(1), 1-5. 34) Hassanzadeh, M.K., Tavacoli, J., Shafiie Miebodi, M. A. M., (2002), Evaluation of acetaminophen concentration in plasma using two different methods of visible spectrophotometry and HPLC. Iranian J. Basic Med. Sci., 5(1): 17-26. 35) Hassanzadeh, M.K., Khashayarmanesh, Z., Shahbazi, H., Shafai, A., (2002), Evaluation of sodium ion and sodium chloride in various kind of bread in city of Mashhad, J. Teb & Tazkieh 46: 48- 54. 36) Ramazanie, M., Hassanzadeh, M.K., Safdarabadi, D. M., (2002), Volatile constituents of Stachys lavandulifolia Vahl. ACGC Chem. Res. Commun., 15: 20-24. 37) Alizadeh, M.H., Razavi, H., Farrash Bamoharram, F., Hassanzadeh, M.K., Khoshnavazzi, R., Mohammadi Zonoz, F., (2003), Novel Catalytic Acetylation of Alcohols with Preyssler s Anion, [NaP5Wa30O110]14 1. Kinetics ans Catalysis, 44(4): 524-528. 38) Tafaghodi, M., Hassanzadeh-Khayyat, M., Rahimizadeh, M., (2003), Isolation and identification of hyoscyamus insanus alkaloids. J. of Medicinal Plants, 2(7): 29-36. 39) Hassanzadeh-Khayyat, M., Khashayarmanesh, Z., Masoomi Shahrbabak, S.H., (2004), Comparison of the amount of Fluoride ion in domestic Iranian toothpastes with few foreign commercial brands and international standards. Beheshti Univ. Dent. J. 22(1): 26-37. 40) Vahdati- Mashhadian, N., Hassanzadeh, M.K., Hosseini, J., Saffareshargh, A. A. (2004), Ethnic differences in the frequency of distribution of serum cholinesterase activity in the Iranian population. Can. J. Physiol. Pharmacol. , 82: 326-330. 41) Emami, S.A., Hassanzadeh, M. K., Rahimizadeh, M., Fazli- Bazzaz. B., Assili, J., (2005), Chemical and antimicrobial studies of Cupressus sempervirens L. cv. Cereiformis Rehd. essential oils, Iranian J. of Pharmaceutical Sciences, 1:33-36. 42) Hassanzadeh, M. K., H. Karimi, (2005), Composition of the volatile oils of three different species of Artemisia (scoparia, diffusa and turanica). Iranian J. of Pharmaceutical Sciences, 1:29-32. 43) Mohammad Reza Shiran, Mohammad Hassanzadeh-Khayyat, Mohammad Zafar Iqbal, Olawale Lagundoye, Nicholas Seivewright, Martin S. Lennard, Geoffrey T. Tucker, Amin Rostami-Hodjegan., (2005), Can saliva replace plasma for the monitoring of methadone. Ther Drug Monit., 27: 580-586. 44) Sadeghnia, H.R.,and Hassanzadeh, M.K., (2005) Comparative bioavailability study of two oral formulations of Ketoconazol tablets in healthy volunteers. Iranian Journal of Pharmaceutical Sciences, 1(4): 209-215. 45) Karimi G., Hassanzadeh, M. and Mehri S. (2005) Protective effect of Rosmarinus officinalis L. essential oil against free radical-induced erythrocyte lysis. Iranian Journal of Pharmaceutical Sciences, 1(4): 231-236. 46) Karimi G., Hassanzadeh, M. and Mehri S. (2006) Protective Effects of Silymarin against Free Radical-Induced Erythrocyte Lysis. Journal of Complementary and Integrative Medicine 3(1): Article 8. 47) Behravan, J., Ramezani, M., Hassanzadeh, M. K., Eliaspour, N. and Sabeti, Z. (2006) Cytotoxic and antimycotic activities of essential oil of Artemisia turanica Krasch from Iran. Journal of Essential Oil Bearing Plants 9(2): 196-203. 48) Emami, S.A., Rahimizadeh, M., Fazli- Bazzaz. B., Assili, J., Hassanzadeh, M. K., (2006), Chemical and antimicrobial studies of Cupressus sempervirens L. and Cupressus horizontalis. Mill. essential oils. Iranian Journal of Pharmaceutical Sciences, 2(2): 103-108. 49) Ajami B., Hassanzadeh-Khayyat M., Mehrabkhani M., Khashyarmanesh, Z. (2006), Evaluation of urinary flouride excretion following NaF mouth rinse prescription in 6-12 years old children. Journal of Dentistry, Mashhad University of Medical Sceinces, 30(3&4): 269-278. 50) Emami, S. A., Asili, J., Mohagheghi, Z., Hassanzadeh, M. K., (2007) Antioxidant activity of leaves and fruits of Iranian conifers., eCAM,March 12, pp 1-7. 51) Behravan, J., Ramezani, M., Hassanzadeh, M. K., Ebadi, S. (2007) Evaluation of Antimicrobial Activity of the Essential oils of Zataria multiflora, Carum copticum and Thymus vulgaris by a Thin Layer Chromatograghy-Bioautography Method. Journal of Essential Oil Bearing Plants 10(3): 259-264. 52) Behravan, J., Ramezani, M., Hassanzadeh, M. K., Eskandari, M., Kasaian, J. and Sabeti, Z. (2007) Composition, antimycotic and Antibacterial activity of Zziphora clinopodioides Lam. Essential Oil from Iran. Journal of Essential Oil Bearing Plants 10(4): 339-345. 53) Hadizadeh, F., Mahdavi, M., Seifi, M., Nassirly, H., Emami, S. A., Asili, J., Khashyarmanesh, Z., Noorbakhsh, R., Shariatimoghadam, A., Hassanzadeh-Khayyat, M. (2007) Evaluation of ISO method in saffron qualification., Acta Hort, Proceeding of IInd Int. Sym.on Saffron Bio. and Techno.,739. 54) Emami, S. A., Javadi, B., Hassanzadeh, M. K., (2007) The Antioxidant Activity of the Essential Oils of Different Parts of Juniperus communis subsp. hemisphaerica and Juniperus oblonga Pharmaceutical Biology., 45 (10): 769-776. 55) Asili, J., Emami, S. A., Rahimizadeh, M., Fazly-Bazzaz, B. S., Hassanzadeh, M. K. (2008) Chemical and antimicrobial studies of Juniperus communis subsp. hemisphaerica and Juniperus oblonga essential oils., Journal of Essential Oil Bearing Plants 11(1): 96-105. 56) Iranshahi, M., Hassanzadeh-Khayyat, M., Fazly Bazaz, B. S., Sabeti, Z., Enayati, F., (2008) High content of polysulphides in the volatile oil of Ferula latisecta fruits and antimicrobial activity of the oil., Journal of Essential Oil Research 20: 183-185. 57) Iranshahi, M., Hassanzadeh-Khayyat, M., Sahebkar A. and Famili A. (2008) Chemical composition of the fruite oil of Ferula flabelliba., Journal of Essential Oil Bearing Plants 11(2): 143-147. 58) Karimi GH., Hassanzadeh M., Shahidi N., Samie Z. (2008) Quantitative determination of methanol in plant water produced in Mashhad by spectrophotometry method., J of Medicinal Plant 7(25): 56-59. 59) Azizi M., Rezvanee F., Hassanzadeh-Khayyat, M., Lackzian A., Neamati H. (2008) The effect of different levels of vermicmpost and irrigation on morphological properties and essential oil content of German chamomile (Matricaria recutita) C.V. Goral. Iranian Journal of Medicinal and Aromatic Plants 24(1): 82-93. 60) Karimi GH., Hassanzadeh M., Yazdanpanah H., Nazari F., Iranshahi M., Nili A. (2008) Contamination of Patulin in clear apple juice in Mashhad, Iran. Journal of Food Safety 28:413-421. 61) Asili, J., Emami, S. A., Rahimizadeh, M., Fazly-Bazzaz, B. S., Hassanzadeh, M. K. (2008). Chemical and antimicrobial studies of Juniperus excela subsp. excels and Juniperus excela subsp. polycarpos essential oils., Journal of Essential Oil Bearing Plants 11(3): 292-302. 62) Karimi G., Hassanzadeh M.K., Nili A., Khashyarmanesh Z., Samiei Z., Nazari F., Teimori M. (2008). Concentrations and health risk of heavy metals in tea samples marketed in Iran. Pharmacologyonline 3: 164-174. 63) Ghani A., Azizi M., Hassanzadeh Khayyat M., Pahlavanpour A. A. (2008) Analysing essential oils of two wild populations of Achillea wilhelmsii C. Koch. J. Sci. & Technol. Agric. & Natur. Resour. 12(45 B) 581-590. 64) Ghani A., Azizi M., Hassanzadeh-Khayyat M., Pahlavanpour A. A. (2008) Essential oil composition of Achillea eriophora, A. nobilis, A. biebersteinii and A. wilhelmsii from Iran., Journal of Essential Oil Bearing Plants 11(5): 460-467. 65) Kalalinia, F., Behravan, J., Ramezani, M., Hassanzadeh, M. K., and Asadipour A. (2008) Chemical composition, moderate in vitro antibacterial and antifungal activity of the essential oil of Pistacia vera L. and its major constituents. Journal of Essential Oil Bearing Plants 11(4): 376-383. 66) Iranshahi, M., Hassanzadeh-Khayyat, M.(2008) Chemical composition of the volatile oil from Ferula ovina (Boiss.) Boiss.-Rech. Fruits. Journal of Essential Oil Bearing Plants 11(4): 350- 355. 67) Valiolahpor R., Rashed M. H. M., Baghestani M., Lakzian A., Hassanzadeh M. K. (2008) Effect of herbicides residue used in rice fields on growth characteristics of second crop in rotation in Mazandaran province. Agricultural Sciences and Technology Journal 22(2): 61-70. 68) Mohammadpoor A. H., Nazemian F., Hassanzadeh-Khayyat M., Naghibi M., Bahrami A., Kazemi M. (2008) Effect of ganciclovir on pharmacokinetics of mycophenolic mofetil, in kidney transplant patients. Iranian Journal of Basic Medical Sciences 10(4): 233-238. 69) Ghani A., Azizi M., Pahlavanpour A. A., Hassanzadeh-Khayyat M. (2009) Comparative study on the essential oil content and composition of Achilla eriophora DC. in field and wild conditions. J. of Medicinal Plant 8(30): 120-128. 70) Ghani A., Saharkhiz M. J., Hassanzadeh-Khayyat M., Msaada K. (2009) Change in the essential oil content and chemical compositions of Echinophora platyloba DC. During three different growth and development stage. Journal of Essential Oil Bearing Plants 12(2): 162-171. 71) Iranshahi, M., Chitsazian Yazdi M., Hassanzadeh-Khayyat M., Sahebkar A. (2009) Sulfur containing compounds in the volatile oil of Ferula latisecta Rech. F. & Aell. leaves. Journal of Essential Oil Bearing Plants 12(1): 64-68. 72) Azizi M., Rahmati M., Ebadi T., Hassanzadeh-Khayyat M. (2009) The effect of different drying methods on weight loss rate, essential oil and chamazolene content of chamomile (Matricaria recutita) flowers. Iranian Journal of Medicinal and Aromatic Plants 25(2): 182-192. 73) Mohsen Forooghipour, Amir Hooshang Mohammadpour, Naser Vahdati Mashhadian, Mohammad Hassanzadeh Khayyat, Mahmood Reza Azarpajouh, Naghmeh Mokhber, Tamara Aghebati, Jamal Shamsara, (2009) Therapeutic drug monitoring of valproic acid in patients with monotherapy at steady state. Iranian Journal of Basic Medical Sciences 12(3-4): 146-149. 74) Mojarab M., Emami, S. A., Hassanzadeh M. K., (2009) Antioxidant activities of methanol extracts of different species of Artemisia from Iran. Pharmacologyonline 2: 797-807. 75) Saharkhiz M. J., Ghani A., Hassanzadeh-Khayyat M. (2009) Change in the essential oil content and compositions of Clay Sage (Salvia sclarea) aerial parts during different phonological stages. Medicinal and Aromatic Plant Sciences and Biotechnology 3(1): 90-93 76) Emami, S. A., Shahidi N. H., Hassanzadeh- Khayyat M. (2009) Antioxidant activities of the essential oils of different parts of Juniperus sabina L. and Juniperus foetidissima Willd. (Cupressaceae). International Journal of Essential Oil Therapeutics 3: 163-170. 77) M. Ebadi, M. Azizi, R. Omidbaigi and M. Hassanzadeh Khayyat, (2009) The effect of sowing date and seeding levels on quantitative and qualitative yield of chamomile (Matricaria recutita L.) CV. Presov. Iranian Journal of Medicinal and Aromatic Plants 25(3): 296-308. 78) Ali Roohbakhsh, Jamal Shamsara, Mohammad Hasanzadeh Khayyat, Gholamreza Karimi (2009), Inhibition of Xanthine Oxidase by Some Iranian Plant Remedies Used for Gout, Pharmacologyonline 3: 1031-1036. 79) Moallem S. A., Karimi G., Hassanzadeh-Khayyat M., Bozorgi M., Nili-Ahmadabadi A. and Nazari F. (2010) Exposure assessment for mercury from consumption of marine fish in Iran. Toxicological & Environmental Chemistry 92(6): 1213-1218. 80) Asili, J., Emami, S. A., Rahimizadeh, M., Fazly-Bazzaz, B. S., Hassanzadeh, M. K. (2010). Chemical and antimicrobial studies of Juniperus sabina L. and Juniperus foetidissima Wild. essential oils. Journal of Essential Oil Bearing Plants 13(1): 25-36. 81) Emami, S. A., Fakhrjafary M., Tafaghodi M., Hassanzadeh M. K., (2010) Chemical composition and antioxidant activities of the essential oils of different parts of Cupressus arizonica greene. Journal of Essential Oil Research 22: 1-7. 82) M. Ebadi, M. Azizi, R. Omidbaigi and M. Hassanzadeh Khayyat, (2010) Effect of sowing date and harvest frequency on flower yield, essential oil percent and composition of chamomile (Matricaria recutita L.) CV. Presov. Iranian Journal of Medicinal and Aromatic Plants 26(2): 213-226. 83) Amirhossein Sahebkar, Mohammad Hassanzadeh-Khayyat M. and Mehrdad Iranshahi, (2010) Quantitative analysis of the Hydro-distilled essential oil of Ferula latisecta Rech. F and Aell. Roots from Iran. Journal of Essential Oil Bearing Plants 13(3): 340-346. 84) Gholamhossein MORAVVEJ, Mohammad HASSANZADEH-KHAYYAT, Salehe ABBAR (2010) Vapor activity of essential oils extracted from fruit peels of two Citrus species against adults of Callosobruchus maculatus (Fabricius, 1775) (Coleoptera: Bruchidae). Türk. entomol. derg., 34 (3): 279-289. 85) Ghani A., Akramian M., Hassanzadeh-Khayyat M., Joharchi M. R. (2010) The essential oil analysis of Pseudohandelia umbellifera (Boiss.) growing in Iran. Journal of Essential Oil Bearing Plants 13(5): 568-574. 86) M. Rahmati, M. Azizi, M. T. Ebadi, M. Hassanzadeh-Khayyat. (2010) The effect of different drying methods on weight loss rate, essential oil and chamazolene content of chamomile (Matricaria recutita CV.) germanian (Diploid) flowers. Iranian Journal of Horticultural Science 24(1): 29-37. 87) Amir Hooshang Mohammadpour, Mohsen Foroughipour, Mahmoud Reza Azarpazhooh, Mohammad Hasanzadeh Khayat, Saeed Rezaee Tamara Aghebati, Jamal Shamsara, (2011). Comparison of valproic acid clearance between epilectic patients and patients with acute mania. Iranian journal of basic medical sciences, 14(6): 546-550. 88) Hassanzadeh, M. K., Emami, S. A., Asili, J., Tayarani Najaran Z. (2011) Review of the essential oil composition of Iranian Lamiaceae. Journal of Essential Oil Research Vol. 23, January/February, 35-74. 89) Askar Ghani, Majid Azizi, Mohammad Hassanzadeh-Khayyat and Ali Asghar Pahlavanpour (2011). Comparison of Chemical Composition of Achillea eriophora and A. wilhelmsii Grown in Wild and Cultivated Conditions in Iran. Journal of Essential Oil Bearing Plants 14 (5): pp 617 – 624. 90) Ramin Rezaee, Mohammad Hassanzadeh-Khayyat, Fereshteh Mehri, Zahra Khashyarmanesh, Hamideh Moallemzadeh, and Gholamreza Karimi, (2011). Determination of parathion, aldicarb, and thiobencarb in tap water and bottled mineral water in Mashhad, Iran. Drug and Chemical Toxicology, 1–7, Early Online. 91) Hassanzadeh- Khayyat M. , Edward P.C. Lai, Kerim Kollu, Banu Ormeci (2011), Degradation of Diclofenac in Molecularly Imprinted Polymer Submicron (Particles by UV Light Irradiation and HCl Acid Treatment, JWARP, Vol.3 No.9, PP.643-654. 92) Emami, S. A., Asili, J.,M. Malekian, Hassanzadeh, M. K.,. (2011) Antioxidant effects of the essential oils of different parts of Platycladus orientalis and their components Journal of Essential Oil Bearing Plants. 14(3): 334-344. 93) Emami, S. A., B. F. Abedindo, Hassanzadeh- Khayyat M. (2011) Antioxidant Activity of the Essential Oils of Different Parts of Juniperus excelsa subsp. excelsa and Juniperus excelsa subsp. polycarpos (Cupressaceae), Iranian Journal of Pharmaceutical Research. 10(4): 799-810. 94) Mitra Hassany, Mohammad Hassanzadeh Khayat , Javaad Behravana and Jamaal Kasaeeian. (2011). Expression of Drug Pump Protein MRP2 in LipopolysaccharideTreated Rats and its Impact on the Disposition of Acetaminophen. Iranian Journal of Pharmaceutical Research, 10 (4): 855-859. 95) Bibi Sedigheh Fazly Bazzaza, Mohamad Hassanzadeh Khayat, Seyed Ahmad Emami, Javad Asilic, Amirhossein Sahebkara;, Elahe Javadi Neishabory. (2011). Antioxidant and antimicrobial activity of methanol, dichloromethane, and ethyl acetate extracts of Scutellaria litwinowii, Science Asia 37: 327–334. 96) D. Rezaei, Gh. Haghnia, A. Lakzian, M. Hassanzadeh Khayyat, H. Nasirly. (2011). Study of Atrazine Biodegradation by Pseudomonas fluorescence and Pseudomonas aeruginosa (In Vitro), Journal of Water and Soil 25(4): 799-806. 97) D. Rezaei, Gh. Haghnia, A. Lakzian, M. Hassanzadeh Khayyat, H. Nasirly. (2011). Biodegradation of various concentration of Atrazine by different Pseudomonas bacteria, Journal of Plant Protection, 25(2): 224-227. 98) Shima Tavallaiea, Mehrnoosh Zobeiria, Zohreh Haghighat-Khazaeea, Mohammad Hassanzadeh-Khayyat, Hooriyeh Nassirlid, BizhanMalaekeh-Nikoueid, Amirhossein Sahebkarb, Majid Ghayour-Mobarhana. (2012). Serum vitamin E concentration in Iranian population with angiography defined coronary artery disease. Asian Biomedicine Vol. 6 (1): 19-25. 99) Ahmad Shanei, Ameneh Sazgarnia, Naser Tayyebi Meibodi, Hossein Eshghi, Mohammad Hassanzadeh-Khayyat, Habibollah Esmaily, Neda Attaran Kakhki. (2012). Sonodynamic Therapy Using Protoporphyrin IX Conjugated to Gold Nanoparticles: An In Vivo Study on a Colon Tumor Model, Iranian journal of basic medical sciences, 15(2): 759-767. 100) Behrouz Akbaria, Faezeh Gharanfolib, Mohammd Hassanzadeh Khayyat, Zahra Khashyarmaneshc, Ramin Rezaeeb and Gholamreza Karimi. (2012). Determination of heavy metals in different honey brands from Iranian markets, Food Additives and Contaminants: Part B: 1–7. 101) Tamara Aghebati, Mohsen Foroughipour, Mahmoud Reza Azarpazhooh, Naghme Mokhber, Mohammad Hasanzadeh Khayat, Naser Vahdati, Amir Hooshang Mohammadpour. (2012). Relationship between Patient Demographic Characteristics, Valproic Acid Dosage and Clearance in Adult Iranian Patients. Iranian journal of basic medical sciences, 15(2): 702-708. 102) Hassanzadeh-Khayyat M., Nasser Vahdati-Mashhadian, Saeed Eghbal (2011), Inter-individual variability of coumarin 7-hydroxylation (CYP2A6 activity) in an Iranian population (in press). List of some of Thesis Supervised 1- Evaluation of the protective effects of Rosmarinus officinalis L. essential oil and Silybum marianum L. seed alcoholic and aqueous extracts against AAPH Induced erythrocytes lysis 2004 2- Antioxidant effect of essential oil of different parts of Juniperus sabina and Juniperus foetidissima 2004 3- The antioxidant activity of the essential oils of Iranian Juniperus oblonga, Juniperus ommunis subsp.hemispherica 2004 4- The antioxidant activity of the essential oils of Cupressus semipervirens L. var. horizentaliss, Cupressus semipervirens L. var. cereinformis and Cupressus semipervirens L. var. fastigigiata DC 2004 5- The antioxidant activity of the essential oils of Iranian Juniperus exelsa and Juniperus polycarpos 2004 6- The antioxidant activity of the essential oils of Iranian Juniperus foetidissima and Juniperus sabina 2004 7- Bioequivalency study of Trimethoprim tablet in comparison with a commercial one 2003 8- Determination of surfactant in Iranian toothpastes and comparison with a few international commercial brands 2002 9- Analysis of Mentha pulegium and Mentha labiatea essential oils and their effect on nausea and vomiting due to chemotherapy 2002 10- Xanthine oxidase inhibitory activity of some medicinal plants 2002 11- Analysis of Essential oil of Nepeta glomerulosa BOISS and isolation and identification it’s terpenoids 2002 12- Determination of nicotine in Iranian cigarettes and tobacco and comparison with foreign cigarette 2002 13- Evaluation of urinary Fluoride excretion in 6-12 year old children in relation to NaF mouth rinse 2002 14- Comparison of amount of excretion of Fluoride after using Fluoride mouthwash in children 2002 15- Analysis of essential oil of Zataria multiflora boiss and isolation and identification it’s terpenoids 2001 16- Bioequivalency study of ketoconazole tablet in comparison with a commercial one 2001 17- Fractionation and analysis of essential oil of Saliva chloroleuca by column chromatography and GC and GC/MS 2001 17- Determination of Fluoride in Iranian toothpastes and their comparison with a few international commercial brands 2001 19- Fractionation and analysis of essential oil of Salvia limbata by column chromatography and GC-Mass. 2001 20- Isolation and identification of the essential oil of Salvia sclarea 2001 21- Evaluation of essential oil in ziziphora clinopodiaides of labiatea 2001 22- Isolation and identification of the essential oils of Marrubium vulgare and Stachys lavandulifolia by GC/MS and isolation and identification of Marrubium vulgare terpenoids 2000 23- Hymenocrater calycinus by GC/MS and Isolation and Identification of the terpenoid compounds of Perovskia abrotanoides karel. 2000 24- Isolation and identification of terpenoides of Ginkgo biloba leaves 2000 25- Evaluation of essential oils in two species Teucrium polium and Phelomis cancellata of Labiatea 2000 26- Evaluation and identification of essential oils in three species of Artemisia(scoparia, turanica, diffusa) 2000 27- Structure Determination of Alkaloids in Heliotropium chorassanicum 2000 28- Analysis of essential oil of Salvia nemorosa and isolation and identification of terpenoids it this plant 2000 29- Bioequivalency study of Co-trimoxazole tablets (Adult) in comparison with a commercial one 2000 30- Analysis of essential oil of Nigella sativa 2000 31- Analysis of essential oils of A. absenthium and A. scoparia, structure elucidation of chemical composition of A. absinthium 1999 32- Seperation, purification and identification of Fumaria indica 1999 33- Isolation and identification of the essential oils of Starchy trineruis 1999 34- Assessment of N-nitrosamine amount in smoke of various cigarettes 1998 35- Relative bioavailability of various Impramine tablets and their comparison with standard 1998 36- Determination of lead in Mashhad vegetable 1998 37- Study methods of bleaching beeswax 1998 38- Evaluation of Essential Oils in Two Species Mentha Longifolia and Serpyllum of Labiatea 1998 39- Ethnic deferences in the frequency of distribution of serum cholinesterase activity in the Iranian population 1998 40- Extraction and identification of alkaloids in Berberis vulagaris leaves 1998 41- Investigation of Chemical Compositions of Dill Oil 1998 42- Isolation and Identification of the essential oils of Perovskia abrotanoides karel and 43- Study of hypoglycemic effect of Salvia lerifolia leaf extract in Mice 1998 44- Evaluation of essential oil in two specis (spearmint and pepper mint) of labiatea 1998 45- Determination the Alkaloids of Fumaria parviflora 1998 46- Determination of Iodine and its stability in various Iodine-salts produced in Khorasan province 1998 47- Comparison of systemic absorption of Fluoride from two different formulation of Sodium Fluoride tablets in children 1998 48- A survey on relative bioavailability of a domestically made sustained release 100 mg Diclofenac tablet, comparing it with the standard preparation 1997 49- Evaluation of chemical compounds of essential oil and resin of Durema ammoniacum 1997 50- Isolation, purification and identification of alkaloids of Berberis vulagris root 1997 51- Extraction, separation and determination of taxol and relative diterpenoids from Iranian Native yew (Toxus baccota L.) 1997 52- Determination of salt in the bread of Mashhad by various methods 1997 53- Study the amount of iodine in Khorasan from production to use 1997 54- Interaction of some drugs on morphine detection in urine 1996 55- A search on gossypol content of cottonseeds in Khorasan and Gorgan provinces by HPLC 56- Interaction of some drugs on morphine detection in urine 1996 57- Evaluation of pH alteration substances on Morphine detection in urine 1996 58- A study of function of 15-Crown-5 as a phase transfer catalysis and evaluation of its toxicity 1996 59- Isolation and Identification of Hyoscyamus insanus Alkaloids 1996 60- Evaluation of Sodium ion and Sodium Chloride in various kind of bread in city of Mashhad 1996 61- Determination the relative bioavailability of Isoniazid tablets 1995 62- Extraction of Malt from grain 1995 63- Evaluation of the effect of temperature on the stability of aqueous Methocarbamol solutions 1995 64- Evaluation of the effect of pH on the stability of aqueous Methocarbamol solutions 1995 65- Determination of dosage regiment of Theophylline in dialysis patients 1994 66- Determination of relative bioavailability of various kinds of Cepharadine capsules 1994 67- Evaluation of amount of Aflatoxin M1 in pasteurized milk of Mashhad 1994 68- Determination of relative bioavailability of sustained release Indomethacin tablets 1994 69- Determination of relative bioavailability of various kinds of Amoxicillin capsules 1993 70- Evaluation of bioavailability of various brands of Cephalexin capsules 1993 71- Structure Determination of Alkaloids in Glaucium elegans 1993 72- Determination of relative bioavailability of various kinds of Oxazpame tablets 1993 73- Determination of Acetaminophen serum concentration using a new spectrophotometric method and comparing with a HPLC method 1993 74- Determination of Carbamazpin and Phenytoin concentrations in blood of patients suffering from epilepsy and their clinical application 1993 75- Formulation of dissolution of Ibuprofen suppositories 1993 76- A search on the possibility of penetration of Thiosulfate into the lipid phase using phase transfer catalysis 1993 77- A computer software for calculations of pharmacokinetic parameters 1992 78- Determination of bioavailability of two domestically-made Ibuprofen in comparison with a standard commercial one 1990 79- Qualitative and quantitative evaluation of various dosage forms of Cephalosporins available in the market 1986 80- Qualitative and quantitative evaluation of various dosage forms of Mefenamic acid available in the market 1986 81- Qualitative and quantitative evaluation of various dosage forms of Amoxicillin available in the market 1985