Cell Division / Mitosis / Cancer / Meiosis – Notes Name: ___________________________________________ Period: _______________ Cell Division Asexual Reproduction: reproduction involving only _____ parent Sexual Reproduction: reproduction requiring ______ parents Chromosomes: molecules of DNA, ______ exist during cell division; numbers vary depending on species ex: Potatoes, plums, and chimpanzees all have 48 chromosomes in each cell. Humans have ______. The Cell Cycle: Stages of the cell cycle Mitosis: ___________ division plus cytokinesis, and produces ____ __________ daughter cells during prophase, metaphase, anaphase, and telophase. Steps of Mitosis Step One: _______________ 1. The chromatin, diffuse in interphase, condenses into chromosomes. Cell Division / Mitosis / Cancer / Meiosis – Notes Name: ___________________________________________ Period: _______________ 2. Each chromosome has duplicated and now consists of two sister chromatids 3. At the end of prophase, the nuclear envelope breaks down into vesicles. Step Two: ______________ 1. Chromosomes align in the middle of the cell 2. Chromosomes are held in place by spindle fibers Step Three: _______________ 1. The centromeres divide. 2. Sister chromatids separate and move toward the end of the cell Step Four: _________________ 1. Daughter chromosomes arrive at the poles and the microtubules disappear. 2. The condensed chromatin expands and the nuclear envelope reappears. 3. The cytoplasm divides, the cell membrane pinches inward ultimately producing two daughter cells Cell Division / Mitosis / Cancer / Meiosis – Notes Name: ___________________________________________ Period: _______________ Results of Mitosis: CYTOKINESIS “packages” the new, genetically identical nuclei produced by mitosis into _________ ____________ cells. ______________ cell – cleavage furrow ______________ cell – cell plate Dividing a Eukaryotic Cell • Example: skin cell Skin cell A skin cell will divide to form two skin cells. The genetic information must be the same. Cell Division / Mitosis / Cancer / Meiosis – Notes Name: ___________________________________________ Period: _______________ _________________: disease caused by severe disruption of the mechanisms that normally control the cell cycle _________ Tumor: mass of cells that remain at their original site ________________ Tumor: mass of abnormal cells resulting from uncontrolled cancer cell division Cell Division / Mitosis / Cancer / Meiosis – Notes Name: ___________________________________________ Period: _______________ Meiosis Sex Cells Males: __ sperm Females: ____ egg & ____ polar bodies Meiosis: the production of ______ cells Steps of Meiosis First Division of Meiosis: Homologous Chromosomes Separate Step One: ________________ 1. Each chromosome duplicates and remains closely associated. 2. These are called sister chromatids. 3. _______________ can occur during the latter part of this stage. Step Two: __________________ 1. Homologous chromosomes align at the equatorial plate. Step Three: __________________ 1. Homologous pairs separate with sister chromatids remaining together. Step Four: ___________________ 1. Two daughter cells are formed with each daughter containing only one chromosome of the homologous pair. Cell Division / Mitosis / Cancer / Meiosis – Notes Name: ___________________________________________ Period: _______________ Second Division of Meiosis: Gamete Formation Step Five: ______________________ 1. DNA does not replicate Step Six: _______________________ 1. Chromosomes align at the equatorial plate Step Seven: ____________________ 1. Centromeres divide and sister chromatids migrate separately to each pole Step Eight: _____________________ 1. Cell division is complete. 2. Four haploid daughter cells are obtained. Results of Meiosis: One parent cell produces four daughter cells. Daughter cells have ___________ the number of chromosomes found in the original parent cell and with crossing over, are genetically different. Meiosis ______________ from mitosis primarily because there are __________ cell divisions in meiosis, resulting in cells with a haploid number of chromosomes. Cell Division / Mitosis / Cancer / Meiosis – Notes Name: ___________________________________________ Period: _______________