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Name:………………………………………..……
GroupA
31.10.2008.
1. How is L. pneumophila transmitted?
a) respiratory droplets
b) foodborne
c) aerosols from contaminated air-conditioning
d) human to human transmission
c)
2. What does "probiotic" mean?
a) clinical syndrome of pneumonia
b) a kind of exotoxin
food ingredients with physiologic effects through the GI tract
d) medium for Lactobacillus culture
3. The best treatment for a patient with “Legionnaire’s disease” is:
a) penicillin
b) cephalosporins
c) erythromycin
d) vancomycin
4. The most important virulence factor of L.monocytogenes is:
a) liseriolysin O
b) exotoxin
c) pyrogenic toxin
d) pertussis toxin
a)
5. Which statement is true for Lactobacillus ?
antibiotic therapy helps the colonization of Lactobacillus
b) maintains low pH
c) production of H O causes epithelium damages
d) none of the above
2
2
6. Among the four presented bacterial species, which one respond to following description: gram-positive rod
with β-hemolysis on blood agar and motility, which causes foodborn disease?
a) Propionibacterium acnes
b) Lactobacillus
c) Legionella pneumophila
d) Listeria monocytogenes
b)
7. Which statement is true for L.monocytogenes ?
a) limits the concentration of potentially harmful germs in the digestive tract
produces an extracellular toxin which lyses membrane-bound vacuoles of epithelial cells and monocytes
c) positively affects the immune response by improving the intestinal microbial balance
d) none of the above
8. Which of the following is the most prevalent microorganism in the oral cavity that may also be protective:
a) Neisseria mucosa
b) Neisseria subflava
c) Lactobacillus sp.
d) Streptococcus mutans
9. A 55-year-old man who is being treated for adenocarcinoma of the lung is admitted to a hospital because of
a temperature of 38.9ºC, chest pain and a dry cough. Sputum is collected. Gram stain of the sputum is
unremarkable and culture reveals many small, gram-negative rods able to grow only on a charcoal yeast
extract agar. This organism most likely is which of the following?
a) Streptococcus pneumoniae
b) Legionella pneumophila
c) N. meningitidis
d) S. aureus
10. Legionnaires' disease is most rapidly diagnosed by which one of the following procedures?
a) Cold agglutinin test
b) Culture of respiratory secretions on a charcoal-based nutrient agar
c) Detection of antigen in respiratory secretions
d) Detection of specific antigen in urine
Name:………………………………………..……
GroupB
1. How is L. pneumophila transmitted?
a) respiratory droplets
b) foodborne
c) aerosols from contaminated air-conditioning
d) human to human transmission
31.10.2008.
2. Due to cold growth some fairly common animal fecal bacteria potentially contaminate some deli meats and
soft cheeses; therefore, renal transplant patients should only have hot deli sandwiches. What is this
causative agent of meningitis in transplant patients ?
a) S.pneumoniae
b) L.pneumophila
c) L.monocytogenes
d) N.gonorrhoeae
3. A 2-year-old child was admitted to the hospital with acute meningitis. The gram-positive, short rods, and
the mother indicated that the child had received “all” of the meningitis vaccinations. What is the most
likely cause of the disease?
a) H.influenzae
b) L.monocytogenes
c) Neisseria meningitides
d) Corynebacterium diphtheriae
4. The Microbiology laboratory has chosen to culture all sputum samples received for Legionellae. Which
medium is more likely to recover the organisms ?
a) cysteine - tellurite agar
b) buffered charcoal yeast extract agar
c) brucella agar
d) potato dextrose agar
5. What does "probiotic" mean?
a) clinical syndrome of pneumonia
b) a kind of exotoxin
c) food ingredients with physiologic effects through the GI tract
d) medium for Lactobacillus culture
6. The best treatment for a patient with “Legionnaire’s disease” is:
a) penicillin
b) cephalosporins
c) erythromycin
d) vancomycin
7. The primary virulence mechanism of L.pneumophila is its:
a) potent cytotoxin that inhibits motility of respiratory cilia
b) proteases that inflict damage to host tissue
c) antiphagocytic capsule
d) ability to induce phagocytosis and survive in the phagosome
8. A major step in the pathogenesis of listeriosis is:
the release of hyaluronidase by L.monocytogenes, which contributes to its dissemination from local sites
b) the antiphagocytic activity of the L.monocytogenes capsule
c) the ability of polymorphonuclear leucocytes to phagocytize and destroy L.monocytogenes early in the
course of the disease
d) the survival and multiplication of L.monocytogenes within mononuclear phagocytes and host epithelial
cells
a)
c)
9. Which statement is true for Lactobacillus ?
a) antibiotic therapy helps the colonization of Lactobacillus
b) limits the concentration of potentially harmful germs in the digestive tract
negatively affects the immune response by improving the intestinal microbial balance
d) none of the above
10. A 55-year-old man who is being treated for adenocarcinoma of the lung is admitted to a hospital because
of a temperature of 38.9ºC, chest pain and a dry cough. Sputum is collected. Gram stain of the sputum is
unremarkable and culture reveals many small, gram-negative rods able to grow only on a charcoal yeast
extract agar. This organism most likely is which of the following?
a) Streptococcus pneumoniae
b) Legionella pneumophila
c) N. meningitidis
d) S. aureus
Name:………………………………………..……
GroupC
31.10.2008.
1. How is L. pneumophila transmitted?
a) respiratory droplets
b) foodborne
c) aerosols from contaminated air-conditioning
d) human to human transmission
2. Due to cold growth some fairly common animal fecal bacteria potentially contaminate some deli meats and
soft cheeses; therefore, renal transplant patients should only have hot deli sandwiches. What is this
causative agent of meningitis in transplant patients ?
a) S.pneumoniae
b) L.pneumophila
c) L.monocytogenes
d) N.gonorrhoeae
3. A 2-year-old child was admitted to the hospital with acute meningitis. The gram-positive, short rods, and
the mother indicated that the child had received “all” of the meningitis vaccinations. What is the most
likely cause of the disease?
a) H.influenzae
b) L.monocytogenes
c) Neisseria meningitides
d) Corynebacterium diphtheriae
4. What does "probiotic" mean?
a) clinical syndrome of pneumonia
b) a kind of exotoxin
c) food ingredients with physiologic effects through the GI tract
d) medium for Lactobacillus culture
5. What organism is most likely responsible for bacterial meningitis in neonates:
a) S.aureus
b) L.monocytogenes
c) C.diphtheriae
d) Lactobacillus sp.
6. A 2-week-year old newborn developed meningitis. Short, gram-positive rods were isolated and identified
as Listeria organisms. The mother had eaten unpasteurized cheese from Mexico during the pregnancy and
recalled having a flulike illness. Listeria monocytogenes causes a variety of diseases, including food
poisoning. Which of the following best describes these microorganism?
a) flagella are produced both at room temperature and at 37ºC
b) Listeria are facultative intracellular pathogens
c) Once infected, the immune system cannot destroy Listeria
d) Listeria cannot be cultivated on artificial media
7. Which statement is true for Lactobacillus ?
a) antibiotic therapy helps the colonization of Lactobacillus
b) maintains low pH
c) production of H O causes epithelium damages
d) none of the above
2
2
8. Pneumonia in an older male heavy smoker and drinker. Two of his bar buddies have the same acute onset
of pneumonia with severe headache, mental confusion, and diarrhea but no sputum. What is the causative
agent is?
a) L.monocytogenes
b) L. pneumophila
c) Enterococcus spp.
d) all of the above
9. Which statement is true for Lactobacillus ?
a) antibiotic therapy helps the colonization of Lactobacillus
b) limits the concentration of potentially harmful germs in the digestive tract
c) negatively affects the immune response by improving the intestinal microbial balance
d) none of the above
10. Legionnaires' disease is most rapidly diagnosed by which one of the following procedures?
a) Cold agglutinin test
b) Culture of respiratory secretions on a charcoal-based nutrient agar
c) Detection of antigen in respiratory secretions
d) Detection of specific antigen in urine
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