Antimicrobial drugs’ activity sheet
1. Antibiosis is
(a) an association between organisms that is injurious to one of them
(b) an antibiotic
(c) narrow-spectrum
(d) broad-spectrum
2. Prokaryotic cells are human cells that are targeted by bacteria.
(a) True
(b) False
3. The way in which an antibiotic attacks a pathogenic microorganism is called
(a) lipophilic
(b) hydrophilic
(c) lipopolysaccharide
(d) antimicrobial activity
4. A super infection is caused by
(a) a pathogen that is resistant to the antibiotic
(b) an infection in deep tissues of the body
(c) an infection that covers a large area of the body
(d) an infection that infects more than two organs
5. What destroys many types of bacteria?
(a) Narrow-spectrum antibiotics
(b) Broad-spectrum antibiotics
(c) Porins
(d) Hydrophilic
6. The bacteriostatic strategy is a direct hit, killing the pathogen.
(a) True
(b) False
7. What is the spectrum of antimicrobial activity?
(a) Broad-spectrum antibiotic
(b) Narrow-spectrum antibiotic
(c) The minimum number of different types of pathogenic microorgan- isms that an antibiotic can destroy
(d) The number of different types of pathogenic microorganisms that an antibiotic can destroy
8. Sulfanilamide is a
(a) Cell wall inhibitor
(b) Protein inhibitor

(c) Antimetabolite
(d) DNA inhibitor
9. The bacteriostasis strategy causes the host’s immune system to fight the pathogen through phagocytosis.
(a) True
(b) False
10. Penicillin is a cell wall inhibitor.
(a) True
(b) False
1.
Identify the contributions of Paul Ehrlich and Alexander Fleming to chemotherapy.
2.
What type of microbes produce the most antibiotics?
3.
Describe the general side effects of antibiotics.
4.
Define the following terms: spectrum of activity, broad-spectrum antibiotic,
Narrow-spectrum antimicrobial.
5.
Identify five modes of action of antimicrobial drugs.
6.
Compare the method of action of penicillin, aminoglycosides, tetracycline and macrolides.
7.
Describe how rifamycins, Polymyxin and quinolones kill bacteria.
8.
Describe how sulfa drugs inhibit microbial growth.
9.
Explain the modes of action of currently used antifungal drugs.
10.
Explain the modes of action of currently used antiviral drugs.
11. Define Bacteriostatic, Bactericidal and Chemotherapeutic index.
12. Explain the modes of action of Praziquantel.
13.
Describe 3 tests for efficacy of antimicrobials.
14.
Describe the mechanisms of drug resistance.
15.
Compare and contrast synergism and antagonism.