Skip to main content Advertisement Menu Search Search Publisher main menu Journals Submissions Publishing services About My Account Follow BioMed Central Twitter Facebook Biology Direct Biology Direct main menu Home About Articles Aims and scope Biology Direct serves the life science research community as an author driven open peer review journal, providing authors and readers with an alternative to the traditional model of peer review. Biology Direct considers original research articles, hypotheses, comments, discovery notes, application notes and reviews in subject areas currently identified as those most conducive to the open review approach, primarily those with a significant non-experimental component. Articles Recent Most accessed Recent articles Recent articles RSS 1. Opinion Just how Lamarckian is CRISPR-Cas immunity: the continuum of evolvability mechanisms Eugene V. Koonin and Yuri I. Wolf Published on: 24 February 2016 2. Application note Altools: a user friendly NGS data analyser Salvatore Camiolo, Gaurav Sablok and Andrea Porceddu Published on: 17 February 2016 3. Review Biochemistry and physiology within the framework of the extended synthesis of evolutionary biology Angelo Vianello and Sabina Passamonti Published on: 9 February 2016 4. Research Characterizing exons and introns by regularity of nucleotide strings Tonya Woods, Thanawadee Preeprem, Kichun Lee, Woojin Chang and Brani Vidakovic Published on: 8 February 2016 5. Research A paneukaryotic genomic analysis of the small GTPase RABL2 underscores the significance of recurrent gene loss in eukaryote evolution Marek Eliáš, Vladimír Klimeš, Romain Derelle, Romana Petrželková and Jan Tachezy Published on: 2 February 2016 View all articles Most accessed articles Most accessed articles RSS 1. Hypothesis Midichlorians - the biomeme hypothesis: is there a microbial component to religious rituals? Alexander Y Panchin, Alexander I Tuzhikov and Yuri V Panchin Published on: 2 July 2014 2. Research The evolution of domain-content in bacterial genomes Nacho Molina and Erik van Nimwegen Published on: 11 December 2008 3. Hypothesis On the origin of life in the Zinc world: 1. Photosynthesizing, porous edifices built of hydrothermally precipitated zinc sulfide as cradles of life on Earth Armen Y Mulkidjanian Published on: 24 August 2009 4. Hypothesis The ancient Virus World and evolution of cells Eugene V Koonin, Tatiana G Senkevich and Valerian V Dolja Published on: 19 September 2006 5. Review Bioinformatics clouds for big data manipulation Lin Dai, Xin Gao, Yan Guo, Jingfa Xiao and Zhang Zhang Published on: 28 November 2012 View all articles Editors-in-Chief Eugene Koonin, NCBI, NLM, NIH, USA Laura Landweber, Princeton University, USA David Lipman, NCBI, NLM, NIH, USA Journal sections Biology Direct publishes in the following sections: Bioinformatics Cell Biology Evolutionary Biology Genomics Mathematical Biology Non-coding DNA & RNA Structural & Molecular Biology Systems Biology For details of Section Editors and Editorial Board members, please see our Editorial Board page. Unique model of peer review Biology Direct offers a novel system of peer review, allowing authors to select suitable reviewers from the journal's Editorial Board; making the peer-review process open rather than anonymous; and making the reviewers' reports public, thus increasing the responsibility of the referees and eliminating sources of abuse in the refereeing process. How it works Impact Factor Biology Direct has an Impact Factor of 4.658, meaning the journal is now ranked in the first quartile of the biology category in the JCR. Submit a manuscript Submission Guidelines Editorial Board Sign up to article alerts ISSN: 1745-6150 Advertisement Contact us Jobs Manage manuscripts Sign up for article alerts Manage article alerts Leave feedback Press center Read more on our blogs Policies Licensing Terms and conditions Privacy statement Accessibility Cookies Follow BioMed Central Twitter Facebook Google Plus YouTube LinkedIn Reddit Weibo © 2016 BioMed Central Ltd unless otherwise stated. Part of Springer Science+Business Media. By continuing to use this website, you agree to our Terms and Conditions, Privacy statement and Cookies policy.