INTRODUCTION TO Biology Biology: The Science of Life Biology as a Science Definition of Biology - Greek words: bios - meaning “life” + logos - meaning “study of” the science of life the study of living things deals with the investigation of the origin, history, structure, function, identification, classification, distribution, development, inheritance, and significance of living things as well as their relationships and interaction with the environment. History of Biology The history of biology can be summarized in four stages namely: 1. Primitive period – characterized by uncritical accumulation of information, accumulated knowledge was not recorded. 2. Classical Period – began with Greeks and continued with the Romans. Marked by great curiosity about natural phenomena and ability to organized biological knowledge and recorded it. 3. Renaissance Period – took place during the 14th – 16th century. Anatomy, physiology, botany and zoology were established in the middle of this period. 4. Modern Era – introduction of microscope marked the start of modern biology. 1 Some World Famous Biologist 1. Andreas Vesalius (1543) – worked on human anatomy and published the book “The structure of the Human body” 2. William Harvey (1628) – discovered the mechanics of human blood circulation which contributes to physiology. 3. Marcello Malphigi (1661) – worked on blood capillaries and completed the path between the arteries and veins. 4. Robert Hooke (1966) – first coined the word cell. 5. Antoni Van Leeuwenhoek – worked on microscopy. 6. Theodore Schwann (1883), Matthias Scheiden (1839) – established the “Cell Theory”. 7. Charles Darwin – an English naturalist, proposed the “Theory ofevolution through natural Selection and published “The Origin of Species” in 1859. 8. Gregor Mendel – made studies on genetics, the “Father of Modern Genetics 9. Louis Pasteur – introduced pasteurization and rabies vaccination, the “Father of Modern Microbiology. 10. Robert Koch – discovered bacteria that causes anthrax, tuberculosis and cholera 11. Sir Alexander Fleming – discovered penicilin Some Filipino Biologist 1. Angel Alcala, Ph.D. – contributed in marine ecology through conservation of coral reefs and captive breeding of Philippine crocodile. 2. William G. Padolina, Ph. D. – multi-awarded in his excellent pioneering researches in biotechnology and chemistry of natural resources. 3. Eduardo a. Quisumbing, Ph.D. – Father of Modern Orchidology. 4. Carmen C. Velasquez, Ph.D. – (National Artist) researched on parasitic worms. 2 Major Branches of Biology 1. Botany – study of plant life. 2. Zoology – study of animal life 3. Microbiology – study of microorganisms Branches according to subject matter or concepts of study: 1. Biosystematics – deals with the identification, naming and classification of organisms. This is the modern term for taxonomy. (plant, animal, microbial systematics) 2. Biogeography – the study of biographical distribution of organisms. a. Phytogeography – plant geography b. Zoogeography – animal geography 3. Molecular Biology or Biochemistry – the study of chemistry of living things. Molecular Biology includes gene biology and aspect of organic chemistry. 4. Cell Biology or Cytology – the study of cells. 5. Histology – the study of tissues. 6. Organismic Biology – the study of organ system. 7. Ecology – the study of interrelationship of organisms and their environment. 8. Morphoanatomy – the study of the gross structure of living organisms. 9. Physiology – the study of biological function. 10. Genetics – the study of heredity and variation. 11. Reproductive Biology – the study of various aspect of reproduction. 12. Developmental Biology – the study of the development of organisms from gamete formation to birth, (embryology) and other developmental processes. 13. Paleontology – the study of fossil records. 14. Evolution – study the origin and differentiation of life. 3 15. Ethology – study of behavior of organisms. 16. Pathology – study of diseases, its nature, causes and symptoms. Subdivisions according to type of organism: Phycology – study of algae Pomology – study of fruit trees Dendrology – study of trees Horticulture – study of vegetable Floriculture – study of flowers Bryology – study of mosses and liverworts 7. Entomology – study of insects 8. Helmintology – study of worms 9. Ichthyology – study of fishes 1. 2. 3. 4. 5. 6. 10. Herpetology – study of reptiles and amphibians 11. Mammology – study of mammals 12. Ornithology – study of birds 13. Parasitology – study of parasites 14. Protozoology – study of singlecelled animals or protozoa 15. Bacteriology – study of bacteria 16. Mycology – study of fungi 17. Virology – study of viruses Unifying Theories of Biology Modern biology is based on several great ideas, or theories: 1. The Cell Theory (Scheiden, 1838, Schwann, 1839, and Virchow, 1858) All organisms are made up of cells, and these cells come from pre-existing cells. 2. Biogenesis (Pasteur, 1865) Life comes only from life. 3. Homoestasis (Bernard, 1858) The internal environment remains within a normal rage. 4. Theory of Evolution by Natural Selection (Darwin, 1858) All the living things have a common ancestor and are adapted to a particular way of life. 5. Gene Theory (Mendel, 1866, Franklin, Watson and Crick, 1953) Organisms contain coded information that dictates their structure, function and behavior. 4 Method of Biology As a science, biology also uses the scientific method in solving or investigating a biological problem. Scientific Method - a systematic method in finding the truth making careful observations and experiments and later using the data obtained to formulate general principle or theories. Steps of Scientific Method 1. Identification of the Problem any scientific process starts with observation using all the senses from the observation a problem may be identified 2. Formulation of the Hypothesis a set of assumption or possible explanation to the problem will be formulated Hypothesis – a set of assumptions or possible explanations to the problem - preliminary conclusion or a scientific/educated guess, tentative or casual explanation for a group of observations. 3. Testing of the hypothesis or experimentation Experiment – is a special procedure used to test the hypothesis 2 Sets of Experiments a. control set-up b. experimental set-up – similar to the control set-up in every aspect except the presence of variable Variable – the factor or parameter to be tested 5 4. Analysis and interpretation of data and results data/results must be gathered during and after the experimentation data include records collected while making observation during an experiment one way to analyze or interpret records of observation is b using tables or graphs 5. Generalization or Formulation of conclusion based from the analyzed data, a theory may be formulated supported by experimental evidence this theory may be developed into a scientific law or into a principle Theory – a hypothesis that has been repeatedly and rigorously tested. Observation Statement of the Problem Formulation of Hypothesis Testing of the Hypothesis Results Expected Results Unexpected Results Generalization Figure 1. The Scientific Method 6 Limitations of the scientific method 1. Existence of God 2. Beauty appreciation 3. Moral Issues 4. Value judgment Nature of Life Life – the sum total of all bodily activities of an organisms. It is sometimes a fork of energy from which all the different worlds of activity could be expressed. Theories on the Origin of Life 1. Divine Creation or Special Creation Theory This theory states that life was presumed to have been created by supernatural power whom we call God. 2. Abiogenesis or Spontaneous Generation Theory Life originated spontaneously from non-living things. Disproved by Francesco Redi, an Italian scientist in 1668, and by Louis Pasteur, a French chemist in 1865 3. Cosmozoic or Interplanetary Theory Life originated from outer planets in the form of a resistant spore propelled by radiation or pressure, reached the earth and started the first form of life. 4. Philosophical Theory of Eternity Life has no beginning and no end. It states that whatever forms of life we have now have actually been here right from the beginning of time. 7 5. Marine Theory Life originated from the sea. 6. Naturalistic or Evolutionary or Physico-chemical Theory The most scientific and the most accepted theory. a. Life came about as a result of a chain of chemical reactions that gave rise to a mass of living protoplasm which then gradually modified, giving rise to the present forms of life. b. This chemical evolution has never been duplicated. Characteristics of Living Things 1. Living things can respond to stimuli. Although all living things respond differently to stimuli, the capacity to respond to those changes in both internal and external environment is the basic function of living things. Stimuli – the physical or chemical changes in the environment. 2. Living things are capable of reproduction. Generation after generation, in order for life to continue, living things must be able to produce other living things of their kind. Reproduction – ability of the organism to create another of the same kind. 3. Living things are capable of adapting to their environment. Living things not suited to a new condition either moves to a better environment or change (evolution). A change cannot occur in one generation but over many generations. Adaptation results into unity and diversity of life. Adaptation – traits that are enhance the individual’s ability to survive in a particular environment. 4. Living things can grow and develop 8 From zygote, a living thing develops changes and grows into a mature organism through several differentiations. They may increase in size accompanied by differentiation of body parts. Growth – increase in the size of cell or number of cell or both Development – slow process of progress change in the organism. 5. All living things can carry on metabolisms. Process required in maintaining their organization, growth and reproduction. Metabolism – the sum of all chemical activities in living organisms. Two phases of metabolism: a. b. Anabolism – forms more complex substances from simpler one resulting in the storage of energy and production of new cellular material. Catabolism – breaks down complex substances to release energy. 6. Living things can maintain homoestasis. Homoestasis – the process by which an organism maintains the constant internal conditions necessary for life. 7. Living things maintain a definite chemical composition All organisms are basically made up of similar inorganic (water, salts, minerals, gases) and organic molecules (carbohydrates, lipids, proteins and nucleic acids.) 8. Living things are capable of movement Animals exhibit this characteristic obviously. Although plants do not move wholly, the organelles inside the cell do move. This is called cyclosis. 9. Living things are capable of taking in energy from the environment and transferring this into another form of energy. Assimilation – the process of converting non-living inorganic and organic molecules into living cell that can be done inside a living cell. 10. Living things are highly organized. 9 Parts of living things are arranged in a particular way. There are levels of biological organization – biochemical, structural, structural, physiological and ecological organization. Levels of Organization Atoms: smallest particle of matter non-divisible by chemical means. Molecules: form when two or more atoms of the same element react with one another or combine with atoms of another element Organelle: A subunit of a cell, an organelle is involved in a specific subcellular function, for example the ribosome (the site of protein synthesis) or mitochondrion (the site of ATP generation in eukaryotes). Cell: The fundamental unit of living things. Each cell has some sort of hereditary material (either DNA or more rarely RNA), energy acquiring chemicals, structures, etc. Living things, by definition, must have the metabolic chemicals plus a nucleic acid hereditary information molecule. Tissue: (in multicellular organisms). A group of cells performing a specific function. For example heart muscle tissue is found in the heart and its unique contraction properties aid the heart's functioning as a pump. Organ: (in multicellular organisms). A group of cells or tissues performing an overall function. For example: the heart is an organ that pumps blood within the cardiovascular system. Organ System: (in multicellular organisms). A group of cells, tissues, and organs that perform a specific major function. For example: the cardiovascular system functions in circulation of blood. Individuals/Organism: One or more cells characterized by a unique arrangement of DNA "information". These can be unicellular or multicellular. The multicellular individual exhibits specialization of cell types and division of labor into tissues, organs, and organ systems. Populations: Groups of similar individuals who tend to mate with each other in a limited geographic area. This can be as simple as a field of flowers, which is separated from another field by a hill or other area where none of these flowers occur. 10 Species: Groups of similar individuals who tend to mate and produce viable, fertile offspring. We often find species described not by their reproduction (a biological species) but rather by their form (anatomical or form species). Community: The relationships between groups of different species. For example, the desert communities consist of rabbits, coyotes, snakes, birds, mice and such plants as sahuaro cactus (Carnegia gigantea), Ocotillo, creosote bush, etc. Community structure can be disturbed by such things as fire, human activity, and over-population. Ecosystem: The relationships of a smaller group of organisms with each other and their environment. Biosphere: The sum of all living things taken in conjunction with their environment. In essence, where life occurs, from the upper reaches of the atmosphere to the top few meters of soil, to the bottoms of the oceans. We divide the earth into atmosphere (air), lithosphere (earth), hydrosphere (water), and biosphere (life). ATOM hydrogen, oxygen MOLECULE H2O CELL neuron ORGAN SYSTEM Nervous system ORGAN brain TISSUE ganglion ORGANISM horse POPULATION Group of horse COMMUNITY horse + insects + trees BIOSPHERE planet + all organisms ECOSYSTEM Horse + other organisms + nonliving organisms Figure 2. LEVEL OF BIOLOGICAL ORGANIZATION 11