CURRICULUM VITAE Name: Place and Date of Birth: Nationality: Address1: João Paulo Isidoro Coelho Amarante, 05/02/1976 Portuguese Valborgsmassovagen 22 126 37 Hagersten Sweden Address2: Carrer Ramon Turró, 41, 3º-2ª 08005 Barcelona Spain Phone: 0046 08 6450194 / 0034 666057652 E-mail: jpicoelho@hotmail.com Academic degrees, fields of study, awarding institutions, dates in reverse chronological order 2006 – PhD thesis (to be presented) 1999 – BSc in Biology, Faculty of Sciences, University of Oporto 1994 – High-school graduation Present position, institution, starting date: Oct. 2002 – June 2006: PhD student at the Molecular Immunopathology Unit DCEXS – Pompeu Fabra University Barcelona Nov.2001 – July 2002: PhD student accepted in GABBA program (Graduation in Basic and Applied Biology Areas) from the University of Oporto Previous experience, Institution July 2001 – Nov. 2001: BTI fellowship of the project “Genetic study of migraine” UnIGENe – IBMC – University of Oporto May 2000 – July 2001: BTI fellowship of the project “Genetic study of spinocerebellar ataxia and hereditary spastic paraplegia” UnIGENe – IBMC – University of Oporto Nov.1999 - May 2000: Trainee student in molecular genetics. UnIGENe – IBMC – University of Oporto Extra activity: Oct. 2004 – Dec. 2005: part-time activity on Barceloca Networks SLU. Courses: May 2001 – Human Gene Mapping Disease, IBMC, University of Oporto May 2000 – Ubiquitin-Mediated Proteolysis: From Cellular Functions to Human Diseases, IBMC, University of Oporto May 2000 – Mechanisms of Brain Protection and Repair, IBMC, University of Oporto Mar. 2000 – New Vectors and Strategies for Gene Therapy, IBMC, University of Oporto Nov. 1999 – ABC of Clinical Genetics, IBMC, University of Oporto July 1999 – Recent Advances in Plant Biology From Stress and Oxygen Radicals to Programmed Cell Death and Senescence, IBMC, University of Oporto Publications: Alonso I, Barros J, Tuna A, Coelho J, Sequeiros J, Silveira I, Coutinho P: Phenotypes of spinocerebellar ataxia type 6 and familial hemiplegic migraine caused by a unique CACNA1A missense mutation in patients from a large family. Arch Neurol 60:610-614, 2003. Silveira I, Miranda C, Guimaraes L, Moreira MC, Alonso I, Mendonça P, Ferro A, Pinto-Basto J, Coelho J, Ferreirinha F, Poirier J, Parreira E, Vale J, Januario C, Barbot C, Tuna A, Barros J, Koide R., Tsuji S, Holmes SE, Margolis RL, Jardim L, Pandolfo M, Coutinho P and Sequeiros J: Trinucleotide repeats in 202 families with ataxia: a small expanded (CAG)n allele at the SCA17 Locus. Arch Neurol 59:623-9, 2002. Presentations Alonso I, Tuna A, Coelho J, Barros J, Sequeiros J, Silveira I, Coutinho P: A missense mutation in a calcium-channel gene causes SCA in a four generation family also with hemiplegic migraine. Am J Hum Genet 69 (4): 2429, 2001. Silveira I, Alonso I, Miranda C, Guimarães L, Moreira MC, Mendonça P, Ferro A, Pinto-Basto J, Coelho J, Ferreirinha F, Jardim L, Coutinho P, Sequeiros J: Trinucleotide and pentanucleotide repeats in 202 unrelated families with spinocerebellar ataxia. Am J Hum Genet 69 (4): 2554, 2001. Coelho J, Alonso I, Barros J, Fraga C, Pereira Monteiro J, Sequeiros J, Silveira I: Caracterização molecular do gene CACNA1A em famílias e doentes com enxaqueca. 7th Meeting of the Portuguese Society of Neuroscience, 2001. Alonso I, Tuna A, Coelho J, Barros J, Coutinho P, Sequeiros J, Silveira I: Mutação missense no gene CACNA1A provoca SCA associada a enxaqueca hemiplégica familiar. 7th Meeting of the Portuguese Society of Neuroscience, 2001. Coelho J, Alonso I, Barros J, Fraga C, Pereira Monteiro J, Sequeiros J, Silveira I: Estudo genético da enxaqueca em 84 famílias e 13 casos isolados. 5th Meeting of the Portuguese Society of Human Genetics, 2001. Alonso I, Tuna A, Coelho J, Barros J, Coutinho P, Sequeiros J, Silveira I: Substituição GA no codão 583 do gene da subunidade 1A do canal de Ca2+ do tipo P/Q causa ataxia dominante progressiva com enxaqueca hemiplégica familiar. 5th Meeting of the Portuguese Society of Human Genetics, 2001. Coelho J, Alonso I, Ferreirinha F, Vale J, Barros J, Mota Vieira L, Coutinho P, Sequeiros J, Silveira I: Caracterização molecular de 27 famílias com paraparésia espástica hereditária. XXXVII Genetics Conference, 2001. Alonso I, Coelho J, Mendonça P, Jardim L, Costa C, Januário C, Pavão I, Tuna A, Barros J, Coutinho P, Sequeiros J, Silveira I: Caracterização molecular do gene CACNA1A em 6 famílias com enxaqueca hemiplégica ou ataxia episódica do tipo 2. XXXVII Genetics Conference, 2001. Homem C, Alonso I, Coelho J, Ferro A, Pinto Basto J, Mendonça P, Matamá T, Ferreirinha F, Tuna A, Jardim L, Barros J, Januário C, Sequeiros J, Silveira I: Análise molecular de 8 genes com repetições de tripletos em famílias com ataxia hereditária. XXXVII Genetics Conference, 2001. . Alonso I, Coelho J, Mendonça P, Jardim L, Tuna A, Barros J, Coutinho P, Sequeiros J, Silveira I: CACNA1A gene polymorphisms in families with episodic ataxia and hemiplegic migraine. Am J Hum Genet 67 (2): 2085, 2000. Coelho J, Alonso I, Jardim L, Barros J, Coutinho P, Ross CA, Holmes SE, Margolis RL, Sequeiros J, Silveira I: The (CAG)n in the PPP2R2B gene associated with SCA12 is not expanded in a large group of Portuguese ataxia families. Eur J Hum Genet 8(1):147, 2000. Alonso I, Coelho J, Mendonça P, Moreira MC, Jardim L, Tuna A, Barros J, Coutinho P, Sequeiros J, Silveira I: Molecular analysis of the CACNA1A gene in patients with episodic and /or progressive cerebellar ataxia. Eur J Hum Genet 8(1):129, 2000. Aditional Information: Spoken Languages: Portuguese (native) English (fluent) Spanish (fluent) French (good knowledge) Catalan (good knowledge) Swedish (basic level) 1994 – 1996: Political leader of the youth section of Juventude Socialista (the youth wing of the Portuguese Socialist Party) of my city (Ermesinde)