Biology
Notes: Human Genome Project
Pre-discussion Questions:
1. What is a genome?
2.
In what year was the human genome sequence completed?
3.
How different is your genome from Ms. Freeman’s? (Give a percent)
4.
How many genes do humans have?
5.
Why do you think the human genome project was established?
What is the Human Genome Project?
What was found?
 Genomes in a human:
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Cells in the human body:
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Chromosomes in a human cell:
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Genes in a Human Genome:
How was it done?
1.
2.
3.
Benefits of the human genome project:
1.
2.
3.
DNA Secret Code of Life VIDEO clip
MOVIE: DNA: The Secret of Life
Watch the movie and answer the questions below:
Post discussion questions:
1. What is a genome?
2.
In what year was the human genome sequence completed?
3.
How many base pairs of nucleotides does the human genome contain?
4.
Based on genome analysis, what percentage of the genome is different among people?
5.
How many genes were found in the human genome? Was this surprising? Why?
6.
List 3 goals of the project.
7.
Why was the human genome project established?
SPACE DOCTORS! http://learn.genetics.utah.edu/content/tech/genetherapy/spacedoctor/
Sequence Yourself http://www.pbs.org/wgbh/nova/body/sequence-DNA-for-yourself.html
Interactive Genome http://genome.wellcome.ac.uk/node30086.html
Genome Facts http://www.pbs.org/wgbh/nova/genome/facts.html
Cracking the Code of Life http://www.pbs.org/wgbh/nova/body/cracking-the-code-of-life.html
Glowing Organisms http://news.nationalgeographic.com/news/2009/05/photogalleries/glowing-animal-pictures/
MOVIE: NOVA Cracking the Code of Life http://www.pbs.org/wgbh/nova/body/cracking-the-code-of-life.html
Watch the movie and answer the questions below:
Post discussion questions:
1. What % of genes in a banana are also found in us?
2. How many more genes do humans have than fruit flies?
3. How long did they predict it would take to decode the human genome?
4. What does Tay Sachs disease do to a babies’ brain?
5. Who does a child get the gene for Tay Sachs from?
6. Where did Craig Venter grow up?
7. What was slowing down the government teams?
8. By early 2000, how many base pairs/sec were rolling out?
9. How many times were the fundamental mechanisms for life worked out on this planet?
10. Why doesn’t work get done on certain regions of DNA molecules?
11. Are genes one-dimensional or 3-dimensional?
12. What do genes do – basically?
13. What was every week like at Solaris?
14. How many of the 17 children have arthritis?
15. What are the “guys in the funny suits” making?
16. BRCA mutations cause what percentage of breast cancers?
17. What would most changes we make to DNA today do to the machine?
18. What do you come away from reading the genome realizing?
19. What can “we and we alone do”?