SEMINAR IN NEUROPSYCHOLOGY ~ ECT 3** Course Description, Spring 2015 ~ Professor: Class meetings: Email: Office hours: Sharon Hannigan, M.A.T./Ph.D. Tuesdays & Thursdays, 9:00-10:20am, Rm. ?? shannigan@nes.ru Tuesdays & Thursdays, 10:30-11:30am, Building 28: Rm. 314 Required materials: PowerPoint Lectures provided by your teacher and based on the text, Human Neuropsychology The Man Who Mistook His Wife for a Hat, and Other Clinical Tales, Pub.: Sacks, Simon & Schuster, ISBN: 0-684-85394-9 Copies of relevant pages provided by your teacher of the coloring book: A Colorful Introduction to the Anatomy of the Human Brain, Pinel & Edwards Course overview: In this course we will explore the effects of brain damage that compromise abilities most of us take for granted such as recognizing what we see, remembering important events, understanding and producing language, experiencing appropriate emotions, and planning for the future - a discipline known as “neuropsychology”. Throughout the semester we will draw on several materials that, combined, will provide us with a comprehensive understanding of the discipline. A theoretical basis for the study of neuropsychology will be established through teacher-prepared PowerPoint lectures based on the acclaimed text, Human Neuropsychology. An adequate neuroanatomical foundation will be acquired through completion of relevant pages in A Colorful Introduction to the Anatomy of the Human Brain, an “anatomically correct” coloring book. Finally, clinical insight into various neuropsychological syndromes (also known as agnosias, or selective losses of knowledge) will come from two different sources. The first consists of the intriguing – indeed shocking – tales artfully set forth by Oliver Sacks in, The Man Who Mistook His Wife for a Hat, serving as the basis for weekly student-led class presentations and discussions. The second source of clinical insight will entail combing the literature and other media in search of a single neuropsychology patient to be inspired by in the “Sacksian spirit” – in the process gaining an appreciation for alternative ways of perceiving, interpreting, remembering, and engaging the world. The case study (patient) you choose will be the subject of your very own “Sacksian Tale”, submissions of which will be bound into a class anthology and shared with classmates during the “end of semester reading”. Learning goals: By the end of this semester and beyond, it is my hope that you: Foundational: Understand basic principles of cortical organization, including general flow of information processing (systems-level approach) Know the six major domains (categories) of human knowledge listed in the syllabus Know the classic agnosias associated with each of the six domains covered Develop the awareness that damage within a single domain can yield several distinct forms of agnosia Can identify, for each domain, the major brain structures that support it Application: Demonstrate the ability to creatively problem-solve in response to a particular neuropsychological deficit (or represent it a sophisticated manner). Integration: Make connections between what you’ve learned in class and the “patients” you see in everyday life Discover systems-level analogs in other disciplines and in the “real world” Human dimension: Observe and celebrate otherness, or alternative ways of engaging the world Contemplate, in the unfortunate event of brain trauma, the potential of becoming “an other”. Reflect on the ever-changing nature of the human condition Caring: Become excited to learn more about the relationships among mind, brain, and behavior and the multiplicity of contexts in which they are embedded Empathize with those suffering from either “losses” of or “excesses” in function as a result of brain trauma Class format: Class meets twice a week for an hour and twenty minutes. Each meeting will consist of three distinct, yet highly interrelated, segments (i.e., Human Neuropsychology, Sacksian Tales, and Colorful Neuroanatomy) each with their own set of learning goals and expectations (see course syllabus). Below I present a general framework of how each class will proceed – but bear in mind that the ultimate form(s) our classes take depends, critically, on you, or more specifically on the relationships that will emerge between you and your classmates as you actively engage course content. Looking at the syllabus, notice that the first class of each week will be devoted to neuropsychological principles essential to an understanding of the neuropsychological deficits and syndromes that will be covered over the semester. In weeks one though four, these principles will be delivered within the context of a systems-level approach to the brain with a focus on cortical organization and flow of information processing. In the remainder of the semester we will visit, in some depth, the following “domains of human knowledge”: language (wks 5 & 6), visual recognition (wk 7), voluntary action (wk 8), memory (wks 10 & 11), emotion (wk 12), and higher-order (executive/prefrontal) function (wks 13 & 14). The second class of each week will be devoted to two separate aspects of the course, namely, clinical tale presentation and discussion leading and essential neuroanatomy. Student-led discussions (details forthcoming) will be based on an assigned clinical tale by Oliver Sacks in his acclaimed book, The Man Who Mistook His Wife for a Hat. Time will also be devoted to preparing for the following week’s content. That is, you will start learning the neuroanatomy essential to understanding “next week’s” neuropsychological domain by completing the relevant sections of your neuroanatomy coloring book (see below and in syllabus). Evaluation: (1) Neuroanatomy quizzes (individual assessment) There will be four quizzes on key neuropsychological principles and neuroanatomy essential to your understanding of the deficits and syndromes explored throughout the semester. The quizzes will be given at the beginning of class on the following dates (tentative): Quiz #1: Quiz #2: Quiz #3: Quiz #4: Thursday, February 12 Thursday, March 5 Thursday, April 2 Tuesday, April 28 (2) Neuroanatomy coloring book exercises (continuous assessment, individual): Weekly “colorful neuroanatomy” exercises, sometimes begun in class and assigned as homework, are a form of “continuous assessment” that will be graded on a scale of 0 to 3 (0 = incomplete/not acceptable; 3 = excellent). (3) Student co-led presentation and discussion based on Sacks’ clinical tales: This assignment is based on the clinical tales in Sack’s book, The Man Who Mistook His Wife for a Hat. The idea is for you and a partner to take full responsibility for first presenting one of his tales and then generating and sustaining a class discussion on it as follows: a. Presentation component (pair work): You and your partner will co-present your clinical tale to the rest of the class by describing (1) the tale’s central characters, events, and concepts, and (2) the spirit in which Sacks wrote the tale. Specific guidelines will be handed out and partnerships established well in advance of the first student-led discussion. PowerPoint and other media are encouraged, here, so long as they enhance – and not detract from – the presentation. Presentation length should be roughly 30 minutes. b. Class discussion co-leading component (pair work): After your presentation, you and your partner will co-lead a whole and/or small group discussion (~30 minutes) based on two (no more, no less!) thought provoking questions that you write yourselves. Your two discussion questions must be emailed to the professor at least one week in advance of your presentation date. The professor will then send your questions to the rest of the class so that they can reflect upon and respond to them in writing before your presentation (see below). c. Audience question response component (continuous assessment): Importantly, audience members must prepare for all clinical tale discussions by responding to the two discussion questions in writing and then emailing them to the professor before the start of every class when tales are to be presented. After the discussion period, the professor will grade audience members’ discussion question responses as a form of “continuous assessment” on a scale of 0 to 3. Late submissions will NOT be accepted, as the main objective of this assignment is to provide a basis for the audience to meaningfully engage in class discussion. (4) Class anthology contribution: “Sacksian tales” (individual assessment): As mentioned in “class format” (above), you will write your very own Sacks-like clinical tale based on a “neuropsychology case study”. The subject of your case study can be someone you personally know (anonymous) or read/seen /heard about in the media or neuropsychology literature. The tales will be collected toward the end of the semester (due date = May 14) and compiled into a class anthology, copies of which will be distributed to each class member. Details forthcoming. (5) Neuropsychology capstone (interactive team presentation): The course capstone, intended as a vehicle for further exploration and creative expression of a particular aspect(s) of neuropsychology, is to be carried out in teams of students. You and your teammates are to choose one of the options listed below as a final project to be presented before the class in the last two weeks of the semester (Weeks 18 & 19). Demos, media, and activities that promote audience interaction are strongly encouraged. a. Design an original (and well-designed!) neuropsychology experiment b. Develop a new neuropsychological test for a particular deficit/syndrome c. Build a brain model of a particular neuropsychological deficit/syndrome NOTE: Your teams’ idea for a capstone project must be cleared with me. You and your teammates are responsible for scheduling a half-hour meeting that will take place in my office prior to spring break. The purpose of this team meeting is for me to perhaps offer some guidance on your project as well as address, early on, any concerns you might have about it. Grading: Component *Quizzes (combined, 5% each) *Continuous assessment (coloring/discussion responses) *Sacks tale co-presentation/co-discussion-leading *Sacksian tale writing, based on case study *Neuropsychology team capstone presentation Pcnt. 20% 20% 20% 20% 20% 100% NOTE: If you receive a failing grade for the course, you will have an opportunity to make up the final grade by redoing all of the course assignments you failed during the semester. All make-ups will occur during make up period, and be evaluated by a committee of three or more faculty members. Conversion table: 100-Point Scale (Quizzes & Assignments) > 95% 90% – 95% 86% - 89% 80% - 85% 76% - 79% 70% – 75% 60% - 69% < 60% Performance Descriptors Brilliant Excellent Almost Excellent Very Good Good Highly Satisfactory Satisfactory Fail 10-Point Scale (Final Grade) 10 9 8 7 6 5 4 1-3 Meeting deadlines for exams and assignments: It is expected that all course assignments will be completed in full and submitted by the due dates specified. Make-up quizzes will not be given unless, of course, there is a legitimate reason, or a “real” emergency, that prevents you from taking the quiz at the designated time. Attendance and active participation: You are expected to attend all classes. If for some very good reason (i.e., sickness or emergency) you are unable to attend a class, you must notify me either by email or phone. Students are responsible for making up missed information and assignments. While in class you are expected to actively participate. This means showing up to class in a timely fashion prepared to discuss the work assigned during the previous meeting (i.e., having read pertinent text and book chapters, prepared and posted Sacks discussion questions on “my.nes”, and completed assigned sections of the neuroanatomy coloring book). Remember that the smooth functioning of our class depends to a great extent on the amount of care and effort you put into the various assignments. It also depends on your willingness to share your understanding of and ask questions about issues related to course content. Academic dishonesty, cheating & plagiarism Academic dishonesty, cheating, and plagiarism will not be tolerated. Please refer to the joint NES/HSE BAE guidelines for policies and procedures. Open door policy: I am happy to meet with you at any point during the semester, whether individually or in groups (e.g., Sacks discussion-leading partners, neuropsychology capstone teams). Please come and see me during my office hours or by appointment if you have questions regarding any aspect of the course. If you are not clear on an assignment or have a question about something presented in class, by all means feel free to contact me. Looking forward to a happy and productive semester! ~ Seminar in Neuropsychology: Class Syllabus ~ Meetings Week 1: Neuropsychology Topics and Events ____________ -Welcoming, introductions, syllabus, materials, course expectations 1/20, 22 -Overview of team projects, contents & preface to The Man Who Mistook His Wife for a Hat Week 2: Human Neuropsychology: General terminology: organization, planes/directions nervous system 1/27, 29 Man Mistook Wife: Introduce student-led discussion assignment, establish partners, circulate & collect reading selection forms Colorful Neuroanatomy wk.3: Chs. 1.1 nervous system divisions, 1.2 CNS divisions, 1.4 spinal cord organization, 2.1 planes, 2.2 directions, 2.3 sides, 5.3 meninges, 5.4 ventricles Week 3: Human Neuropsychology: Basic principles of brain organization 2/3, 5 Man Mistook Wife: Part I Introduction: Losses, p. 3; Part II Introduction: Excesses, p. 87, Part III Introduction: Transports, p. 129; Part IV Introduction: The World of the Simple, p. 173 Colorful Neuroanatomy wk.4: Chs. 5.6 commissures, 7.1 major fissures, 7.2 lobes, 7.3 major gyri, 7.6 primary sensory and motor areas Week 4: Human Neuropsychology: Forebrain: cerebral cortex Man Mistook Wife: Ch.23, The Twins, p. 195 2/10, 12 Colorful Neuroanatomy wk.5: Chs. 6.4 diencephalon: thalamus, 8.3 ear to cortex, 8.4 cortical auditory areas, 12.1 Wernicke-Geschwind model *Neuroanatomy Quiz #1 (through wk 3) Week 5: Human Neuropsychology: Language: characteristics, the aphasias Man Mistook Wife: Ch. 9, The President’s Speech, p. 80 Colorful Neuroanatomy wk.6: Chs. 12.2 cortex: reading, 12.3 cortex: naming objects Human Neuropsycholoy: Language: major components of language, right hemispheric contributions Man Mistook Wife: Ch.21, Rebecca, p. 178 Colorful Neuroanatomy wk.7: Chs. 8.1 eye to cortex, 8.2 cortical visual areas Human Neuropsychology: Visual Recognition Man Mistook Wife: Ch.1, The Man Who Mistook His Wide for a Hat, p. 8 2/17, 19 Week 6: 2/24, 26 Week 7: 3/3, 5 Colorful Neuroanatomy wk.8: Chs. 9.1 sensorimotor cortical pathways, 9.2 primary motor cortex, 9.5 cerebellum and basal ganglia, 7.8 basal ganglia, (inspect only: 9.3 & 9.4 descending dorsolateral & ventromedial motor pathways) *Neuroanatomy Quiz #2 (through wk 6) Week 8: Human Neuropsychology: Ch.9 all, Voluntary Action Man Mistook Wife: Ch.5, Hands, p. 59 Colorful Neuroanatomy wk.10: Chs. 7.7 limbic system, 10.1 hippocampus & H.M., 10.2 rhinal cortex 3/10, 12 Week 9: Human Neuropsychology: Ch. 10 pp. 255-283, Memory: overview of memory system, medial temporal lobe amnesia Man Mistook Wife: Ch.15, Reminiscence, p. 132 Colorful Neuroanatomy wk.11: Chs. 10.4 medial diencephalon, 10.5 basal forebrain 3/17, 19 Week 10: Week 11: ~ N O C L A S S E S (March 23rd - 29th): C O N S U L T A T I O N W E E K ~ Human Neuropsychology: Ch. 10 pp. 283-301, Memory: diencephalic and working memory impairment Man Mistook Wife: Ch.2, The Lost Mariner, p. 23 3/31, 4/2 Colorful Neuroanatomy wk.12: Ch. 11.3 mesotelencephalic dopamine system and pleasure, 11.4 neural mechanisms of fear and anxiety *Neuroanatomy Quiz #3 (through wk 10) Week 12: Human Neuropsychology: Ch. 11 pp. 323-338, Emotion: emotional memory, cortex and emotion, emotion and conscious experience Man Mistook Wife: Ch.19, Murder, p. 161 Colorful Neuroanatomy wk.13: Ch. 12.5 prefrontal cortex lesions Human Neuropsychology: Ch.12 pp. 339-363, Prefrontal Cortex: working model and impairment in function Man Mistook Wife: Ch.12, A Matter of Identity, p. 108 4/7, 9 Week 13: 4/14, 16 Colorful Neuroanatomy wk.14: Ch. 7.5 secondary and association areas, Ch. 12.4 cortical areas involved in thinking Week 14: Human Neuropsychology: Ch.12 pp. 363-378, Prefrontal Cortex: theories of function Man Mistook Wife: Ch.13, Yes, Father-Sister, p. 116 Colorful Neuroanatomy: Major divisions of prefrontal cortex, cytoarchitecture 4/21, 23 Week 15: 4/28, 30 Week 16: Week 17: *Neuroanatomy Quiz #4 (through wk 14); In-class work and consultations: Sacksian Tales based on Neuropsychology Case Studies ~ N O C L A S S E S (May 1st - 11th): S P R I N G B R E A K ~ *Sacksian tales due on 5/14! Last minute preparations for Team Capstone Presentations! 5/12, 14 Week 18: Assembly of Sacksian Tales into class anthology (division of labor)! Start Team Capstone Presentations! 5/19, 21 Week 19: Team Capstone Presentations, cont. 5/26, 28 Week 20: HSE FINALS WEEK (Sacksian Tale “End of Semester Reading”!) 6/1-6 ~ NOTE: The syllabus may be subject to change throughout the semester. ~