Urinary System Cleaning up the system Parts Kidney - filters the blood Ureter – transports the waste material to the bladder Urinary Bladder – stores the waste products Urethra – releases waste products out of the body Kidney Located next to the vertebral column. ◦ Top about even with the 12th thoracic vertebra and the bottom about even with the 3rd lumbar vertebra Reddish brown, bean shaped ◦ Adults about 13 cm long, 6 cm wide, and 3cm thick Located in a fibrous capsule Function Maintain homeostasis by regulating the blood pH, volume, and composition ◦ Removes metabolic wastes from blood ▪ Are diluted with water and electrolytes to make urine Secretes erythropoietin – controls rate of red blood cell production Helps activate vitamin D Secretes renin, an enzyme that maintains blood volume and pressure Structures Renal sinus – hollow chamber where blood vessels, nerves, lymphatic vessels and the ureter enter and leave Renal pelvis – superior end of the ureter expanded into a sac inside the renal sinus Renal medulla – inner region of the kidney composed of the renal pyramids Renal cortex – outer shell around medulla that dips into the medulla to create the renal columns Nephrons – the functional unit of the kidney about 1 million/kidney To clean blood, you need blood Renal Artery ◦ Branches from the abdominal Aorta ◦ 15-30% of total cardiac out put is sent to the kidneys when you are at rest ◦ The renal artery branches into smaller and smaller vessels until it becomes the afferent arterioles that lead to the nephrons Renal Vein ◦ “Clean” blood travels through ever larger vessels to the renal vein ◦ Empties into the Inferior Vena Cava that leads to the heart Okay, we got blood, now it is the nephron's turn Blood vessels become tangled into a glomerulus which is located in a glomerular capsule (AKA Bowman's capsule) ◦ Fluid in the blood is filtered into the capsule ( the proximal end of the renal tubule) Renal tubule becomes highly coiled then dips down into the Loop of Henle ◦ This is interlaced with capillaries ◦ Fluid is returned to the blood and electrolyte balances are fine tuned here The renal tubule climbs back up and empties into the collecting duct – we now have urine We got urine... now what? The collecting ducts merge together and empty into a minor renal calyx which in return empties into a major calyx, which them empties into the renal pelvis, which empties into the ureter The ureter is a tube that leads to the urinary bladder ◦ Uses peristaltic waves to move the urine down its length We made it to the bladder A hollow, distensible, muscular organ ◦ Stores urine and then forces out the urethra ◦ In the pelvic cavity, behind the symphysis pubis and under the parietal peritoneum ◦ A sphincter at the neck of the bladder hold urine in until the pressure inside is to a certain level Involuntary control ◦ External urethral sphincter – skeletal muscles – voluntary control Micturition AKA urination How do we know to go? By the amount there ◦ 150 ml typically = urge to go ◦ 300 ml sensation of fullness, bladder contraction intensify ◦ 600 ml typically = pain Bladder signals spinal cord, which releases involuntary sphincter, you feel like you must go External urethral sphincter is released when you go to the restroom.