Name:
Date:
Class:
Human Karyotyping WebQuest
Go to the following website: http://learn.genetics.utah.edu/units/disorders/karyotype/ and click on “What is a
Chromosome?.” Answer the following questions?
1) How is a chromosome different from DNA
2) How many PAIRS of chromosomes are in the human body?
How many total?
3) We all have two copies of each chromosome, one from our
4) What is the genotype of sex chromosomes for a male?
and one from our
A female?
5) Do all organisms have 46 chromosomes? Explain.
Close the animation and click on “How do Scientists Read a Chromosome?.” Answer the following questions?
6) What 3 features do scientists look for to distinguish between chromosomes?
a)
b)
c)
7) What do we call the “bands” on chromosomes and how does this help us to pair them together?
8) Name and draw the three types of centromere positions below:
Return to the previous page by clicking on "Heredity and Traits" or the “Back” button. Click on “Making a
Karyotype.” Answer the following questions:
9) What is a karyotype?
10) How are karyotypes made?
11) Complete the activity Matching up chromosomes in a Karyotype. Print out completed karyotype and
submit for a grade.
12) What is the gender of the person whom you are karyotyping? How do you know?
Gender:
How do you know?:
Return to the previous page by clicking on "Heredity and Traits" Now click on “Using Karyotypes to Predict
Genetic Disorders”
13) How many autosomes and sex chromosomes are in a normal human karyotype?
a)
Autosomes:
Sex Chromosomes:
Read and watch the animation for “Normal Meiosis.” Answer the following questions?
14) How many chromosomes are ova and sperm left with after normal meiosis?
Read and watch the animation for “Fertilization.” Answer the following questions?
15) If eggs and sperm only have one set of chromosomes, then how do we end up with 46 chromosomes?
16) What do you call a fertilized egg with 46 chromosomes?
Read and watch the animation for “Abnormal Meiosis.” Answer the following questions?
17) How is it possible that after meiosis some gametes have too many and some have too few chromosomes?
Read and watch the animation for “Trisomy.” Answer the following questions?
18) What do you call it when someone has an extra chromosome?
19) How many total chromosomes does a person have who has trisomy?
Read and watch the animation for “Monosomy.” Answer the following questions?
20) What do you call it when someone has a missing chromosome?
21) How many total chromosomes does a person have who has monosomy?
Go to http://www.biology.arizona.edu/human_bio/activities/karyotyping/karyotyping2.html and click on
“Complete Patient A’s Karyotype.”
22) What notation would you use to characterize Patient A's karyotype?
23) What diagnosis would you give patient A?
24) Describe Patient A’s medical history.
Click on “Patient B”
25) What notation would you use to characterize Patient B’s karyotype?
26) What diagnosis would you give Patient B?
27) Describe Patient B’s medical history.
Click on “Patient C”
28) What notation would you use to characterize Patient C’s karyotype?
29) What diagnosis would you give Patient C?
30) Describe Patient C’s medical history.