5th ANNUAL ENGINEERING GRADUATE STUDENT SYMPOSIUM BOOK OF ABSTRACTS October 23, 2004 University of Michigan Department of Mechanical Engineering Ann Arbor, MI `` 5th Annual Engineering Graduate Student Symposium OCTOBER 23, 2004 BOOK OF ABSTRACTS Organized by: Department of Mechanical Engineering http://me.engin.umich.edu Department of Biomedical Engineering http://www.bme.umich.edu Symposium Organizers (ME , BME and KAIST): Bryon J Sohns Grant M Reeves Amit Dhingra Sanghum Baik Gerald I Fernandes Sangati Seth Harish Narayanan Honghai Zhu Linda Chow Junsok Jee Yonggyun Yu Advisor: Professor Arvind Atreya `` Jeffrey A Meganck Vinod K Natarajan Jianpeng Yue Laura Elgas Alisha B Diggs Adrianne L Prysock Dhruv Sud Ruth R Cheng Jeung Hoon Lee Jun Youn Lee Hyun Jun Shin Sponsored by: http://www.bme.umich.edu/ http://www.kaist.ac.kr/ http://www.engin.umich.edu `` Schedule of Events Saturday, October 23, 2004 8:15-9:00 Registration 9:00-11:30 Morning Sessions Dynamics, Systems and Controls – EECS 1200 Design and Manufacturing – EECS 1311 Design and Manufacturing – EECS 1500 Fluid Mechanics and Heat Transfer – EECS 1001 Solid Mechanics and Materials – EECS 1003 Biomechanics – EECS 1303 11:30-12:00 KAIST Presentation 12:00-1:00 Lunch & Posters 1:00-1:30 Lawrence Livermore National Labs Presentation 1:30-4:00 Afternoon Sessions Dynamics, Systems and Controls – EECS 1200 Dynamics, systems and Controls– EECS 1311 Design and Manufacturing – EECS 1500 Fluid Mechanics and Heat Transfer – EECS 1001 Materials and Biomaterials – EECS 1003 Joint Biomedical Engineering Session – EECS 1303 4:30-5:00 `` Awards Presentations Dynamics, Systems and Controls Chair: Sanghum Baik Session I A - EECS 1200 Gi-Hun Yang 17 Study of Human Tactile Perception Characteristics Using an Integrated Tactile Display System Jing Zhou Range Policy of Adaptive Cruise Control Vehicles for Improved Flow Stability and String Stability 18 Burit Kittirungsi Modeling of the HMMWV for advanced hybrid and power-train studies 19 Jongchul Jung Observer Design with Stochastic and Deterministic Robustness 20 Ardalan Vahidi Explicit and Implicit Load Governors for Constraint Management of a Fuel Cell Air Supply System 21 Chair: Jeung Hoon Lee Session II A – EECS 1500 Bryon Sohns Determining Model Accuracy as a Function of Inputs and System Parameters 22 Dongsoo Kang 23 Creation of Milliken Moment Diagrams Using Time Integration of Controlled Dynamic Vehicle Models Ashish Deshpande A Framework for Physical Cooperation Among Robots for Mobility Improvement 24 Young-Chul Choi Detection of Bearing Fault Signal in Noise 25 Jeung-Hoon Lee A mathematical model of pneumatic vibration isolator 26 `` BoHa Lee Design of the Electromagnetic Actuator with Permanent Magnet for the High Efficiency and Small Size 27 Chair: Sanghum Baik Session II B – EECS 1200 Andreas Malikopoulos Intergraded Starter Alternator (ISA) in a Hybrid Propulsion System 28 Denise McKay Development and Validation of a Real Time Estimator for Fuel Cell Membrane Humidity 29 Kyungwon Suh Power control strategy for fuel cell electric hybrid vehicle 30 Chia-Jui Chiang Steady-State Multiplicity and Stability of Thermal Equilibria in Homogeneous Charge Compression Ignition (HCCI) Engines 31 Jinming Liu Power Train Analysis and Control for Hybrid Electric Vehicle Toyota Prius 32 Design and Manufacturing Chair: Jianpeng Yue Session I A – EECS 1311 April Bryan Compliant analysis with consideration of welding distortions 33 Andres Clarens 34 Comparison of vegetable and petroleum base oils in metalworking fluids using the tapping torque test Farhad Ameri Digital manufacturing market: the IT infrastructure for virtual manufacturing in distributed environments 35 Chino Imediegwu Compliant part assembly modeling and dimensional variation diagnosis using designated component analysis 36 Fu Zhao A transport model approach for developing micro-filtration compatible metalworking fluids 37 `` Honghai Zhu Swing arm design in micro internal combustion swing engine (micse) 38 Chair: Junsok Jee Session I B – EECS 1500 Shingo Takeuchi Design for product-embedded disassembly 39 Zhijun Li Tolerance allocation in compliant multi-station assembly through variation propagation and analytical target cascading HyunSeok Choi Reliability analysis by five-level doe method 40 Mohammed Shalaby Design of heat-reversible snap fits for space frame bodies 41 Rahul Bagdia Customer demand satisfaction in production systems: random correlated demand case 42 Geol Choi Improvement of mechanism of automatic book punching and binding machine using axiomatic design Chair: Jianpeng Yue Session II – EECS 1311 Karim Hamza Vehicle crashworthiness design via equivalent mechanisms and crash mode matching 43 Luis E Izquierdo Control of the assembly process 44 Jeremy Michalek Preference coordination in engineering design decision-making 45 Yonggyun Yu Development of a cad-based general purpose optimal design system and its application to structural shape for fatigue life 46 Junsok Lee Manipulation of micro/nano particle using nanotweezer 47 `` Fluid Mechanics and Heat Transfer Chair: Gerald Fernandes Session I – EECS 1001 Timothy Jacobs The Development of a Low-NOx, Low-Soot Diesel Engine Combustion Strategy 48 Jonathan Hagena The Impact of Fuel Injection Pressure on the Combustion, Emissions, and Performance of a Medium-Duty Diesel Engine 49 Alexander Knafl Dual-Use Engine Calibration: Leveraging Modern Technologies to Improve PerformanceEmission Tradeoffs 50 Aristotelis Babajimopoulos A Fully Integrated CFD and Multi-zone Model with Detailed Chemical Kinetics for the Simulation of HCCI Engines 51 Ronald Grover Transient spray cone angles in Pressure-swirl Injector sprays 52 Fu Zhao Modeling of Porous Filter Permeability via Image-Based Stochastic Reconstruction 53 Session II – EECS 1001 Amit Dhingra 54 Direct modeling support to the development of compact fuel processor systems for PEM fuel cell application Jingjing Li A Computational Study of Catalytically Assisted Combustion in a Stagnation Point Flow 55 Songtao Tang Numerical modeling of radiative extinction of spherical diffusion flames under microgravity conditions 56 Cheensu An 57 Flow and heat transfer analysis for the performance improvement of Cross-flow fin-tube heat exchangers Chan Kwok Leung Paddy Thermal Management of Slab-Coupled Optical Waveguide Lasers (SCOWL) 58 Xiulin Ruan Temperature-Dependent Luminescence Quenching in Random Nano Porous Media 59 `` Solid Mechanics and Materials Chair: Jun Youn Lee Session I – EECS 1003 Jiayin Lee Transient Solution of The Inhomogeneous Thermoelastic Contact Problem Using Fast Speed Expansion 60 Jon Kadish The Effect of Accretion on the Stress Field of Small Planetary Bodies 61 Kyoo-Sil Choi Frequency Drops in Resonant Bending Fatigue Tests of Notched Crankshaft Sections 62 Yeonseok Choo Hybrid Trefftz Formulation in Finite Element Method and its Application on Plane Elasticity 63 P.-C. Lin and S.-H. Lin Microstructures and Failure Mechanisms of Spot Friction Welds in Lap-Shear Specimens of Aluminum 6111-T4 Sheets 64 Chang Qi and Z.-D. Ma 65 Preliminary Studies on Buckling and Crashworthiness Design with Multidisciplinary Objectives and Uncertainties in the System Biomechanics Chair: Adrianne L Prysock Session I – EECS 1303 Jiro Doke Dynamic Modeling of Karate Front Kick 66 Lisa C. Case A Comparison of the Forward Fall Arrest in Healthy Young Men and Women 67 Jaebum Son The Effect of Aging on the Muscle and Neural Control Delay 68 Jeongho Kim Mathematical Modeling to Predict RV Function During Artificial Lung Attachement 69 Taeyong Kim Mechanical Response Of The Extracellular Layers of Sea Urchin Eggs 70 Sachin Goyal Structural Modeling of DNA Loops in Lac-Repressor 71 `` Ken Kozloff 72 Homozygosity for a Dominant Mutation in col1a1 Restores Bone Phenotype in Comparison to Moderately Severe Type IV Osteogenesis Imperfecta Present in Heterozygous Brtl Mice Jeff Meganck Thrombospondin-3 Effects on Bone Structure and Function 73 Materials and Biomaterials Chair: Linda Chow Session I – EECS 1003 Himabindu Nandivada Reactive Polymer Coatings 74 L. N. Luong and R. J. Patel Spatial Control of Protein within Biomimetically Nucleated Mineral 75 Jun-Youn Lee Ultrasonic Transmission Characteristics of Continous Casting Slab for Medium Carbon Steel 76 Sung-tae Hong Effects of Impact Velocity on Crush Strength of Aluminum Honeycombs 77 Ji-Ho Lim and Seok-Bong Kim High Speed Tensile Test for the Material Properties at the Intermediate Strain Rate 78 Kristen Mills The Behavior of Plasma Oxidized Polydimethylsiloxane 79 Woosung Choi A Study on Interfacial Delamination in Thin Film Structure by Pull Test 80 Joint Biomedical Engineering Session Chair – Ruth Chen, Dhruv Sud, Alisha Diggs Session I – EECS 1303 Konstantinos Varsos Micro-device for manipulating and shaping cells in tissue engineering. 81 Kimberly Cook 82 An algorithm for design of power systems for single and multi-component devices: a case study focusing on a MEMS environmental test monitor `` Mohammad Reza Abidian Nano-tubular structured conducting polymers for neural prostheses applications 83 Rebecca C. Booi 84 Quantitative Contrast Analysis of In Vivo Ultrasound Imaging: A Study with a Combined 3D Ultrasound/Digital Mammography System. Huzefa Neemuchwala Entropic Graphs for Simultaneous Multi-image Registration and Atlas Construction. 85 Kiran. K. Pandey 86 Effects of acquisition parameters and reconstruction methods on the correction of motion and susceptibility artifacts in fMRI. Marwa J. Zohdy Optical and ultrasonic monitoring of laser-generated intracellular contrast agents: initial cell culture studies. `` 87 Posters Dynamics, Systems and Controls Bryon Sohns Determining Model Accuracy as a Function of Inputs and System Parameters 88 Bin Wu 89 Using Neural Network Surrogate Models to Optimize the Valve Timings for a 2.4 Litter VVT Engine Byunghoon Ko CT-free Cup Orientator Using Sensors In THR 90 Wan-Ho Cho A Study on the Design of an Acoustic Actuator Based on the Singing Mechanism of Cicadas 90 Design and Manufacturing Emanuel Almeida Modular logic control for reconfigurable manufacturing systems 91 Christine Vehar Closed-loop tape springs as fully compliant mechanisms - preliminary investigations 92 Jie Luo Machining of elastomers 93 Hyunjun Shin 93 Development of 3d position tracking system using psd(position sensitive detector) sensors for surgery Scott Miller Characterization of friction drilling process: force, torque, temperature, and material analysis 94 Zhenhua Huang Optical methods for reconfigurable precision measurement 94 Chino Imediegwu Compliant part assembly modeling and dimensional variation diagnosis using designated component analysis 95 `` Karim Hamza Vehicle crashworthiness design via equivalent mechanisms and crash mode matching 96 Mohammed Shalaby Design of heat-reversible snap fits for space frame bodies 96 Fu Zhao A transport model approach for developing micro-filtration compatible metalworking fluids 97 Jeremy Michalek Preference coordination in engineering design decision-making 97 Shingo Takeuchi Design for product-embedded disassembly 98 Fluid Mechanics and Heat Transfer Kim Hyoun Jun Numerical Simulation of Combustion Driven Oscillations in Gas Turbine 99 Cheensu An 99 Flow and heat transfer analysis for the performance improvement of Cross-flow fin-tube heat exchangers James Smith 100 Cycle-Resolved Charge Evolution Measurements In A Direct Injected Engine Using DoublePulse LIF Meng-Ping Chang 100 Electrokinetic Pumps for Dynamic Actuation of Cochlear Implants during Surgical Insertion Fu Zhao Modeling of Porous Filter Permeability via Image-Based Stochastic Reconstruction 101 Xiulin Ruan Temperature-Dependent Luminescence Quenching in Random Nano Porous Media 101 Aristotelis Babajimopoulos A Fully Integrated CFD and Multi-zone Model with Detailed Chemical Kinetics for the Simulation of HCCI Engines 102 Tershia Pinder 102 An Experimental Investigation of the Effect of Fuel Concentration on Nonpremixed Jet Flames `` Melissa Chernovsky 103 Effect of Increase in CO2 Concentration on Radiative Properties of Unsteady Spherical Diffusion Flames in Microgravity Ronald O. Grover Transient Spray Cone Angles in Pressure-swirl Injector Sprays 103 Biomechanics Jiro Doke Dynamic Modeling of Karate Front Kick 104 Jeongho Kim Optimized Design of a Thoracic Artificial Lung Using Computational Fluid Dynamics 105 Hogene Kim Human balancing strategy used by riding bicycle as slow as possible 105 Ken Kozloff 106 Enhanced Mineralization and Reduced Toughness in the Aging Brtl Mouse Model for Type IV OI Materials and Biomaterials Ji-Hoon Kang 107 Analysis of Polymer Deformation in Nanoimprint Lithography by using Molecular Dynamics Simulation Woosung Choi A Study on Interfacial Delamination in Thin Film Structure by Pull Test 107 Joint Biomedical Engineering Session Chen Nelson A 3D Dual-Transducer Ultrasound Technique for the Assessment of Vascular Flow using Contrast Agent Imaging 108 Inamdar V. Munish Stochastic Simulation of Biometal Binding to Protein Sensors 108 `` Andrea Lo The Effects of Low Frequency Ultrasound on Droplets and Bubbles 109 Huzefa Neemuchwala Multi-image Registration and Image Atlas Reconstruction using Entropic Graph Based Mutual Information Estimation 109 Sun Min Kim Electrokinetic phenomena during electroelution from clinical sampling strips 110 Jungwoo Lee Inverted Colloidal Crystals as a Tissue Engineering Scaffold 110 Yoko Kamotani 111 Microfluidic Immunoassays using a Braille Display for Computer-controlled Fluid Actuation Jonathan W. Song Endothelial Cell Culture Under Computer-controlled Flow in Microfluidic Channels 111 Rainer Ng 112 Effect of contraction-induced injury in young mice lacking superoxide dismutase or glutathione peroxidase genes Mohammad Reza Abidian Nano-tubular structured conducting polymers for neural prostheses `` 113 Dynamics, Systems and Controls Study of Human Tactile Perception Characteristics Using an Integrated Tactile Display System Gi-Hun Yang, Ki-Uk Kyung, and Dong-Soo Kwon yanggh@robot.kaist.ac.kr Keywords: tactile sensation, tactile display, kinesthetic force feedback, vibration, static pressure This paper investigates three experiments on human tactile sensitivity using an integrated tactile display system. The device can provide vibration, normal pressure and lateral slipstretch motion, all of which are important physical quantities of sense texture. We investigated three things: an efficient method of stimulating, limitation of surface discrimination based on kinesthetic force feedback, and the effectiveness of combining kinesthetic force feedback with tactile feedback. Seven methods were tested using the following elements individually or in combination: kinesthetic force, normal static pressure, vibration, active and passive shear and moving waves. A prototype specimen and a stimulus were presented to all examinees via a tactile display. The examinees were asked to nominate the most similar sample. The experimental results show that static pressure is a suitable stimulus for displaying the micro shape of the surface, whereas a vibrating stimulus is more effective for displaying a fine surface. We also compared the sensitivities of active touch and passive touch. Although kinesthetic force feedback is suitable for displaying the shape and stiffness of an object, the roughness display suffers from a limited resolution. As a result, the methods of kinesthetic and tactile feedback are applied concurrently to simulate physical properties while an object is being touched. The integrated tactile display mouse is expected to give users a more realistic sense of touch in a virtual environment; for example in online shopping, CAD or other tangible spaces. We plan to develop a tactile display algorithm to realize physical quantities such as the spatial period, amplitude and element magnitude of a texture. The algorithm will also be applied to our system. `` 17 Dynamics, Systems and Controls Range Policy of Adaptive Cruise Control Vehicles for Improved Flow Stability and String Stability Jing Zhou and Professor Huei Peng jzhouz@umich.edu Keywords: Adaptive Cruise Control, range policy, string stability, traffic flow stability Adaptive Cruise Control (ACC) is designed to provide enhanced driving convenience and comfort. Before ACC vehicles are deployed on a large scale, their string behavior and flow characteristics need to be carefully investigated. Two of the most important macroscopic behaviors of ACC vehicles are traffic flow stability and string stability. An ACC range policy should be designed to satisfy such properties as improved traffic capacity and flow stability, closeness to human behavior, insensitivity to velocity variation, and so on. However it is shown that the conventional Constant Time-Headway (CTH) policy and the range policy inherently used by human drivers always lead to flow instability when the traffic is constrained. In this study a nonlinear range policy is proposed. This quadratic policy is obtained through an optimization procedure with traffic flow and stability constraints imposed, and it competes favorably with the CTH policy, the range policy employed by human drivers and the Greenshields policy. A complementary controller is then designed to implement the proposed range policy, which is based on the sliding mode technique. The desired acceleration is synthesized from the current acceleration, the range rate and the compound range error. String stability condition is derived for this combination of range policy and control law. A microscopic highway merging simulation is set up to verify the effectiveness of the nonlinear controller to maintain the proposed range policy. Results show that stable traffic flow is achieved by the proposed method, up to a significantly higher traffic density, whereas congestion will occur if the CTH or a Gipps model based human driver behavior is assumed. The companion control law proves to be effective in regulating the inter-vehicle range and preserving string stability for the nonlinear range policy. `` 18 Dynamics, Systems and Controls Modeling of the HMMWV for advanced hybrid and powertrain studies Burit Kittirungsi and Dr.Loucas Louca This work mainly focuses on the modeling of the vehicle dynamics and drivetrain models of the HMMWV vehicle, which are developed within the Vehicle Engine Simulation (VESIM) environment, allowing easy evaluation of different vehicle configurations. These models are developed mostly using the components library, which contains models and sub-models previously used within VESIM. Proper models are always critical for providing accurate predictions of vehicle performance as well as fuel economy. The complete vehicle model is validated and the parameters are fine-tuned so the performance agrees with the data collected from the actual vehicle. Then, the simulation with different advanced engine models is evaluated. The result reveals a promising benefit gained from using a new, high boost V6 engine. In addition, the Integrated Starter Alternator (ISA) is added into the system to give mild hybridization, which further improves the performances and provides quantitative insight into benefits of potential modernization of this vehicle platform. `` 19 Dynamics, Systems and Controls Observer Design for Stochastic and Deterministic Robustness Jong Chul Jung, Kunsoo Huh, and Jeffrey L. Stein jongchul@umich.edu, khuh2@hanyang.ac.kr, stein@umich.edu Keywords: Robustness, Observer, Stochastic Uncertainty, Deterministic Uncertainty An observer design method for stochastic and deterministic robustness is developed so that an observer is less sensitive to uncertainties in transient and steady-state. The uncertainties include not only deterministic factors such as unknown initial estimation error, round-off error, modeling error and sensing bias, but also stochastic factors such as disturbance and sensor noise. From a stochastic perspective, a small value in estimation error variance represents robustness to the stochastic uncertainties. It is shown that the upper bound of the error variance can be minimized by reducing the observer gain and by increasing the decay rate of the observer. From a deterministic perspective, a small value in the L2 norm condition number of the observer eigenvector matrix guarantees robust estimation performance to the deterministic uncertainties. In this paper, two design methodologies are developed for both the stochastic and the deterministic robustness. One is a graphical approach to get a feasible region of the observer gain determined by specified design constraints on the cost functions. The observer gain selected in this feasible region guarantees the robustness in the observer performance. The other is an optimization approach by solving an optimization problem. The cost function is expressed as a weighted sum of the objective functions and its constraint is expressed as the linear matrix inequality representing the quadratic stability. Simulation examples demonstrate that it can provide the best estimation performance between the stochastic and the deterministic robustness depending on the application environment. `` 20 Dynamics, Systems and Controls Explicit and Implicit Load Governors for Constraint Management of a Fuel Cell Air Supply System Ardalan Vahidi avahidi@umich.edu Keywords: Model Predictive Control, Reference Governors, Fuel Cell, Compressor Surge In fuel cell powered vehicles, a performance bottleneck is posed by the air supply system. In a high pressure Proton Exchange Membrane (PEM) fuel cell, a compressor supplies air to the cathode. The compressor itself consumes up to 30% of fuel cell generated power and therefore its size has direct influence on overall system efficiency. A centrifugal compressor is prone to surge or choke during load transients and is limited in the amount of air it can provide to the fuel cell stack. The air supply system is susceptible to saturation during rapid transients which are typical of a drive cycle. Measures need to be taken to prevent issuing commands that result in constraint violation. In this work we design load governors as add-on devices to the air supply control system to prevent compressor surge and choke and avoid oxygen starvation in the cathode. A load governor, added to the air supply control system, monitors the load transients and filters them if necessary, to prevent constraint violation. In principle a load governor design is based on some form of constrained optimization. To implement the load governor in memory and chronometric constrained automotive microcontrollers, it is desirable to reduce the online computational load as well as RAM and ROM storage. An ideal load governor is not overly conservative, while requires minimal online computational resource. In this work we develop a load governor using two approaches. The first approach is based on model predictive control and is referred to as implicit. The model predictive controller solves a constrained optimization problem online and modifies the reference accordingly. The second approach is based on fast reference governor and is referred to as explicit. In the fast reference governor, a large portion of computations is carried offline, rendering the online part computationally less demanding. We discuss the performance and computational requirement of each scheme. `` 21 Dynamics, Systems and Controls DETERMINING MODEL ACCURACY AS A FUNCTION OF INPUTS AND SYSTEM PARAMETERS Bryon Sohns, Prof. Jeffrey L. Stein bsohns@umich.edu Keywords: Model Accuracy, Model Validation Vital to the effectiveness of simulation-based design is having a system model of known quality. Previous research introduced an algorithm called AVASIM for assessing model validity systematically and quantitatively. AVASIM assess the accuracy and validity of a model based on a specific input and set of system parameters. The purpose of this presentation is to present a AVASIM-based methodology that defines a range of validity of a model with respect to input and system parameter variations Two illustrative examples are presented to explore the feasibility of the proposed procedure. The first example analyzes a linearized version of a nonlinear transient vehicle-handling model. This model’s accuracy and validity are evaluated with respect to variation of two system parameters, resulting in a two-dimensional range of validity. Then a complex nonlinear hydrogen fuel cell model is linearized in order to investigate its accuracy and validity with respect to two input parameters. This again results in a two-dimensional range of validity, but with respect to input rather than system parameters. The results agree well with what is expected for the various models based on knowledge of the effects of linearization on model accuracy. The proposed algorithm for assessing model range of validity is a promising tool for determining model quality and thus potentially useful for simulation-based design. `` 22 Dynamics, Systems and Controls Creation of Milliken Moment Diagrams Using Time Integration of Controlled Dynamic Vehicle Models Dongsoo Kang and Professor Jeffrey L. Stein dskang@umich.edu The Milliken Moment Diagram (MMD) is a compact presentation of the results from a kinematically constrained vehicle test to assess the handling performance capability of the vehicle. The MMD is the yaw moment versus lateral acceleration for given vehicle sideslip and steering angle. Front and rear tire traction boundaries are easily defined. The MMD is traditionally created in a physical experiment or from steady-state vehicle model. This paper proposes a new procedure for creating MMD using numerical time integration of a controlled vehicle dynamic model. More specifically nonlinear dynamics models such as CarSim, are embedded in a control structure that modulates the vehicle yaw moment to achieve a desired sideslip angle. This control structure can be implemented in a control software such as Simulink and the resulting system numerically integrated. This controlled dynamic system mimics the effect of the constrained physical experiment. MMDs based on a nonlinear vehicle dynamics models are compared with those from simpler bicycle and 3-degree of freedom models showing that the understeer coefficient is best predicted by the nonlinear model. A previously published MMD using a superimposed stereotype transient vehicle maneuver creates stability and controllability margins. These margins are easily generated and combined on the diagrams produced by the new proposed procedure. The same vehicle dynamics model is used for both generating the MMD and the superimposed transient response. In conclusion this procedure allows the user to create an MMD from any existing vehicle models by simply adding the necessary control logic as described within. This allows the user to evaluate the effects of many nonlinear factors by simply including them or excluding them from the vehicle models. `` 23 Dynamics, Systems and Controls A Framework for Physical Cooperation Among Robots for Mobility Improvement Ashish Deshpande and Jonathan Luntz adeshpan@umich.edu Keywords: Mobile Robots, Mobility, Cooperation A team of small, low cost robots instead of one large, complex robot is useful in operations such as search and rescue, urban exploration, etc. However, the performance of such a team is limited due to restricted mobility of the team members. We advocate the idea that through physical cooperation between members, the team of robots can improve its overall mobility, with the underlying philosophy of simplicity to minimize or eliminate the need for addition actuation and communication for cooperation. We propose to develop a generalized framework for the analysis and development of cooperative maneuvers among multiple cooperating mobile robots. As a case study of cooperative maneuvers, we start with the goal of improving the ability of a pair of robots to cross a wide gap. We analyze the statics and dynamics of this maneuver to establish rules for designing a linkage and to develop decentralized control laws to minimize requirements such as ground friction and wheel torque. We demonstrate the working of this system with a hardware implementation to prove that a simple, low cost system can achieve improved mobility via cooperation. We then present ideas for a generalized representation framework based on adaptations of concepts from cooperative manipulation. This framework will provide us the means of analyzing and designing a broad class of cooperative maneuvers including gap spanning, step climbing, and the crossing of rough and/or slippery terrain. `` 24 Dynamics, Systems and Controls Detection of Bearing Fault Signal in Noise Young-Chul Choi, Choon-Su Park, and Yang-Hann Kim(s) youngcc@kaist.ac.kr Keywords: fault detection, bearing fault, minimum variance cepstrum Various bearings are commonly used in rotating machines. The noise or vibration signals that can be obtained from the machines often convey the information of faults and these locations. The condition monitoring of bearings has received considerable attention for many years, because the majority of problems in rotating machines are caused by faulty bearings. Thus failure alarm for the bearing system is often based on the detection of the onset of localized faults. The early fault signal that is caused by a microscopic crack is commonly embedded in noise. Therefore, the success of detecting a fault signal is completely determined by a method’s ability to distinguish signal and noise. In 1969, Capon[1] coined a maximum likelihood(ML) spectrum which estimates a mixed spectrum consisting of a line spectrum, corresponding to a deterministic random process, plus an arbitrary unknown continuous spectrum. The unique feature of this spectrum is that it can detect a sinusoidal signal imbedded in noise. Our idea essentially comes from this method. In this paper, a technique, which can detect an impulse embedded in noise, is introduced. The theory of this technique is derived and the improved ability to detect the faults in a ball bearing system is demonstrated theoretically as well as experimentally. The bearing fault period make it possible to detect the localization as well as the presence of the faults. This is because the location (for example, inner race, outer race, and ball element) of the fault determine the period of impulse train. We have performed the experiments for automobile HUB bearings. After completing experiments, we have taken the HUB bearing to apart, and then observed the fault. It is noteworthy that we have detected 4 fault HUB bearings among the normal 12 HUB bearings which are confirmed by the bearing company. Experimental results show that the proposed technique is quite powerful in the detection of fault in noisy environments. In other words, it is possible to detect faults earlier than before by using this. [1] J. Capon, 1969, Proceedings of the IEEE, Vol. 57, No. 8, August, pp.1408-1419, High-Resolution Frequency-Wavenumber Spectrum Analysis. `` 25 Dynamics, Systems and Controls A mathematical model of pneumatic vibration isolator Jeung-Hoon Lee and Professor Kwang-Joon Kim olo@kaist.ac.kr Keywords: Pneumatic vibration isolator, complex stiffness A pneumatic vibration isolator is widely used in precision engineering department, such as nano-scale measurements, optical experiments and semiconductor manufacturing, since it can provide low stiffness and superior damping characteristics which might vary with frequency and excitation amplitude. To better understand such a device, several mathematical models had been proposed by earlier researchers. But, an experimental data for their validation of the proposed model shows significant errors which are caused by the nonlinear behavior of capillary tube and diaphragm, component of the isolator. Thus, an analysis of fluid flow in the capillary tube was re-examined and an extraction of complex stiffness of diaphragm was studied. The improved mathematical model of pneumatic vibration isolator with the inclusion of the refined model of capillary tube and the complex stiffness of diaphragm exhibits a quite good match with experimental results. All the things mentioned above will be introduced during the presentation. `` 26 Dynamic, System and Controls Design of the Electromagnetic Actuator with Permanent Magnet for the High Efficiency and Small Size BoHa Lee and ChongWon Lee bhlee@novic.kaist.ac.kr cwlee@novic.kaist.ac.kr Keywords: Electromagnetic actuator, Position estimator, Hall sensor As a dynamic actuator for attenuating the engine-induced vibration transmitted to passenger vehicle chassis or investigating the vibration transfer path of the vehicle, an electromagnetic actuator, consisted of a runner, two stators and pairs of electromagnets and permanent magnets, is developed. It features that it is compact to be fit into the limited space and yet, it possesses high efficiency and wide frequency bandwidth for effective control of engine vibrations in standard size passenger cars. By using the permanent magnets in electromagnetic system, we can increase the actuating force of the electromagnetic system and decrease the total amount of the power consumption of actuator when it operates. In addition to that an electronic circuit device is also developed such that the displacement between the electromagnet pair and the target can be estimated from measurement of flux density of the installed permanent magnet only. It is found that the resolution and frequency bandwidth of the displacement estimator are about 3m and 0 to 4kHz, respectively. The electromagnetic actuator with the permanent magnet is capable of attenuating the vibration over the frequency range of 100 to 400Hz, which is satisfactory for applications of interest. And it uses the 12V power supply for commercial use of the designed actuator in vehicles. `` 27 Dynamics, Systems and Controls Intergraded Starter Alternator (ISA) in a Hybrid Propulsion System Andreas Malikopoulos, Professor Dennis Assanis and Dr. Zoran Filipi amaliko@engin.umich.edu Keywords: intergraded starter alternator (ISA), fuel consumption, powertrain simulations This study is motivated by the endeavor of improving the fuel consumption of a medium tactical truck (FMTV). An Intergraded Starter Alternator (ISA) is modeled in Simulink and a ruled based algorithm is developed operating as a power management control. A previous Simulink based model of the medium truck including the driver model, engine, drivetrain and vehicle dynamics is used as a platform for the simulation. The comparison of the fuel consumption among the powertrain architecture with ISA, the parallel hybrid powertrain architecture and the conventional one will be presented. This study extends previous and ongoing work on physics based, integrated, advanced powertrain simulations in order to include hybrid components and various hybrid vehicle architectures. The objectives are to: Develop physics based models of propulsion components for Hybrid Powertrains and integrate them with the Diesel Engine, Driveline and the Vehicle Dynamics to generate the complete Hybrid Vehicle Systems Simulation. Integrate hybrid components within the flexible simulation framework(s) suitable for studies of in-vehicle transients, power management, fuel economy and emissions potential of hybrids vehicles. Support cross-cutting projects, such as target cascading optimization efforts, NVH studies in and potential application of advanced powertrain tools in the virtual proving ground. The predictive simulation tools allow systematic evaluation of the fuel economy potential of various hybrid concepts, thus facilitating decision making process and selection of design. Integrated, feed-forward, flexible simulation allows optimization studies of component sizes and development of optimal power management strategies `` 28 Dynamics, Systems and Controls Development and Validation of a Real Time Estimator for Fuel Cell Membrane Humidity Denise McKay and Professor Anna Stefanopoulou dmckay@umich.edu Keywords: fuel cell, membrane humidity, estimation Proton exchange membrane fuel cells (PEMFCs) chemically combine hydrogen and oxygen to produce electricity, water and heat. As with all power systems, PEMFCs may experience environmental extremes. Such widely varying operating conditions greatly impact the control of cell humidification and water removal. Consequently, maintaining an adequate cell water balance is critical to optimizing cell performance. The difficulty of sensing humidity, combined with the importance of this variable motivates an estimator design. To this end, this work develops, parameterizes and validates a model for estimating cell electrode relative humidity in real time without expensive measurements that require unrealistic stack instrumentation. The ability of the membrane to conduct protons is linearly dependent upon its water content. On one hand, as membrane water content decreases, ionic conductivity decreases, observed by a decrease in the cell voltage. This decrease in efficiency results in increased heat production which evaporates more water, in turn lowering membrane water content, creating a positive feedback loop resulting in hot spots (membrane damage). On the other hand, excessive water stored in the electrodes obstructs fuel flow, resulting in cell flooding. In both cases, the water concentration in the electrodes is important in optimizing fuel cell efficiency and reliability. A model of the water vapor transport through the membrane of a PEMFC for different electrode vapor concentrations was identified using mass conservation with temperature, pressure, mass flow and relative humidity measurements. We demonstrate that this lumped parameter model can be used to accurately capture the spatially averaged phenomena under certain conditions. The functional relationship between the diffusion coefficient and membrane relative humidity was experimentally calibrated for a 24 cell, 1.4 kW fuel cell stack. The experimental method devised for model parameterization is simple and reproducible. In contrast, existing methods for identifying the critical process parameters require extensive membrane conditioning and cell disassembly. The cathode and anode outlet relative humidity were then estimated and compared with experimental results. These results demonstrate the capability of the proposed estimator in accurately predicting electrode exhaust relative humidity of both the cathode and anode of a multi-cell PEMFC stack. Our estimation scheme may be used as a virtual sensor for start-up diagnostics. `` 29 Dynamics, Systems and Controls Power control strategy for fuel cell electric hybrid vehicle Kyungwon Suh and Anna Stefanopoulou kwsuh@umich.edu Keywords: PEMFC, electric hybrid vehicle, DC-DC converter, multivariable control Proton exchange membrane fuel cells (PEMFC) are typically augmented with additional electric energy storage devices such as batteries and ultracapacitors in vehicle propulsion applications. The resulting hybrid system is essential for autonomy in startup and fast power response. Overall efficiency of fuel cell can be maximized with reusable energy captured in battery from regenerative braking. System integration and control issues are associated with various propulsion power configurations with the fuel cell stack, DC-DC converter and battery. Although many power management strategies already exist, the electric (voltage and current) architecture of the hybrid PEMFC vehicle is still under intense debate and investigation. In this presentation the electric architecture of fuel cell hybrid vehicle and associated control issues will be covered. We first present physic-based models that combine (i) reactants supply dynamics of the fuel cell stack, (ii) power electronics of DC-DC converter, and (iii) battery. We then formulate the multivariable controllers and finally derive the optimal control design for various electric architectures of a hybrid PEMFC vehicle. Our results provide insight on the fundamental system controllability and ability to handle transient loading depending on the choice of the electric architecture. `` 30 Dynamics, Systems and Controls Steady-State Multiplicity and Stability of Thermal Equilibria in Homogeneous Charge Compression Ignition (HCCI) Engines Chia-Jui Chiang and Professor Anna Stefanopoulou cjchiang@umich.edu Keywords: stability, HCCI, autoignition The stability of the autothermic process governing the autoignition of HCCI (Homogeneous Charge Compression Ignition) engines is analyzed in this work. We find conditions under which steady-state multiplicity exists with stable, unstable, and limitcycle equilibria. This analysis is conducted taking into account the internal feedback structure of the thermal autoignition dynamics. Specifically, HCCI autoignition timing determines the combustion heat produced and is determined by the heat provided through high internal exhaust gas recirculation from previous combustion cycle. It is shown that the thermal equilibria are characterized by a simple returning map consisting of two curves, namely the breathing temperature curve and the combustion temperature curve. The returning map and the stability analysis of the multiple steady state equilibria is confirmed with a high order dynamic nonlinear model that includes manifold filling and composition dynamics. The existence of multiple steady state temperature equilibria and their stability is very important for controller design. For instance, this information clarifies how sensitive the HCCI engine is and how easy it is to move from a stable equilibrium to an unstable equilibrium region due to perturbations coming from model uncertainty and input disturbances. The result in this work after verified experimentally will guide our future efforts in defining the conditions for stabilization under limited information. Our analysis is essential for understanding the HCCI engine operation and crucial for controller design. With better understanding on the region of attraction of the multiple equilibrium points, a robust controller for the HCCI engine can be developed. `` 31 Dynamics, Systems and Controls Power Train Analysis and Control for Hybrid Electric Vehicle Toyota Prius Jinming Liu and Prof. Huei Peng jinmingl@umich.edu Keywords: Hybrid Electric Vehicle, Power Management Control, Control Optimization Hybrid electric vehicle (HEV) has drawn more and more attention in recent years. Toyota Prius, as the first HEV entered the US market, is still playing an important role. It has a unique power split system design with a planetary gear set which makes it potentially improvable. More degree of freedom is allowed to be provided into such system which can be benefited with more sophisticated control strategy. To analyze and optimize the possible power management control strategy, an integrated Prius power train model is developed in Simulink (See figure 1). It consists of four parts, vehicle data source, vehicle dynamics, power management controller, and other elements, as highlighted in different colors. All initial conditions and parameters are defined in the data source blocks and loaded before running the Simulation. The vehicle dynamic model presents the planetary gear set power transfer relation. Necessary power components (e.g. engine, motor, etc.) are simulated during the simulation process. The power management controller is to be tuned in the optimized control strategy to operate the entire system. Figure 1: Prius Power Train Simulink Model. This study will focus on the power train modeling analysis and the power management control. The vehicle simulation model, especially the power split and control parts, and the driving performance will be presented. `` 32 Design and Manufacturing Compliant Analysis of Aluminum Intensive Frame Structures A. Bryan J. Hu abryan@umich.edu jackhu@umich.edu Keywords: aluminum, arc welding, frame structures, variation analysis Due to the high strength-to-weight ratio, availability and low cost of aluminum, aluminum intensive frames have gained increasing use in the automotive industry. These structures usually consist of extruded and stamped components that are arc welded together. The high thermal and electrical conductivity of aluminum structures result in non-linear stress distributions in the final assembly. This non-linear behavior often leads to inaccurate predictions of final assembly deviations and gross errors in tolerance analysis and synthesis studies when traditional rigid body and compliant methods of analysis are used. This research proposes a generalized model for the prediction of the final assembly deviation of an aluminum structure once the incoming part variations are known. The non-linear stress distributions of the aluminum structure are caused in a large part by the heat generated during the arc welding process and the material properties of the component. The resulting distributions are also dependent on assembly forces and welding parameters. Empirical data will be used to determine the factors that have the greatest influence on the assembly deviation. These factors will be used to create a simplified model that linearizes the relation between the incoming part variations and the final assembly deviation. The sensitivity values obtained could then be used for tolerance studies of these structures. `` 33 Design and Manufacturing EXPERIMENTAL COMPARISON OF VEGETABLE AND PETROLEUM BASE OILS IN METALWORKING FLUIDS USING THE TAPPING TORQUE TEST Andres Clarens and Steven Skerlos aclarens@umich.edu, skerlos@umich.edu Keywords: Metalworking fluids, vegetable base oils, EP additives, particle size, tapping torque test Traditional metalworking fluid (MWF) formulations have been associated with a number of environmental and health concerns that have driven recent efforts to develop new formulations based on alternative vegetable and ester based feed stocks. This study uses the tapping torque test to compare the performance of five base oil feedstocks for MWFs: naphthenic mineral oil, a 50/50 blend of naphthenic and paraffinic mineral oil, soybean oil, canola oil (75% oleic content), and a TMP Ester. The five oils were tested as straight oils, and as soluble oil and semi-synthetic MWFs, to understand the impacts of emulsification on base oil performance. Machining performance was evaluated using a modification to the standard tapping torque test (ASTM D 5619) previously established by the authors. Over 25 tapping torque experiments were conducted for each test fluid to ensure the statistical significance of our results. The results indicate that as straight oils all vegetable based stocks perform significantly better than the mineral oils. This trend holds, although is much less pronounced, after the vegetable stocks are emulsified into soluble oil and semi-synthetic MWFs. The results also indicate that some vegetable oil base stocks have a higher potential for lubricity than others, with data revealing that the soy and TMP ester provide improved tapping torque efficiency relative to canola oil in emulsified MWFs. Ongoing and future work will further develop these vegetable-based formulations to withstand the operating conditions of the manufacturing environment. Current work in emulsion stability under hardwater conditions shows that the vegetablebased fluids are more stable than mineral-based formulations. Separate experiments indicate that vegetable-based surfactant packages are more compatible with microfiltration than commercial mineral based alternatives. Microfiltration of MWFs removes microorganisms, waste grease, and particulates so that the fluid can be recycled and maintained at a high quality. Traditional fluids tend to foul filters, making the process expensive, but the vegetable based alternatives foul filters less readily and could make microfiltration of MWFs a more widely adopted practice in manurfacturing settings. Future work in alternative extreme pressure additives that are non-chlorinated and inherently benign will complement the current research in bio-base oils to yield complete MWF systems that are environmentally preferable to existing option. `` 34 Design and Manufacturing Ontology-based Data Modeling in Digital Manufacturing Market Farhad Ameri and Professor Deba Dutta amerif@engin.umich.edu Keywords: product lifecycle management, manufacturing market, web ontology Product development today is no longer an internal job performed thoroughly within the four walls of a single company but it is accomplished through collaboration between multidisciplinary and cross-functional teams distributed geographically. Internal organization, together with suppliers and customers altogether form the product value chain and -as the building blocks of the Extended Enterprise-they are all closely involved in the design process. Success of product development projects is determined by the ability to leverage the Extended Enterprise’s intellectual assets. Product Lifecycle Management (PLM) is a business strategy that creates an environment in which the intellectual assets are proactively captured, managed and reused. One core concept of PLM is to make product definition information interoperable for all participating agents throughout the product value chain. Data interoperability is a complex problem because it deals with the data format rather than its carrier. One solution for data interoperability problem is implementation of a neutral language for data exchange which encodes the product information in the semantic level. If all participating agents commit to a common language with shared conceptualization, modeling style, vocabularies and taxonomies -which altogether form the semantics- then data exchange would be much more efficient and at the same time, machine level data interoperability would be enabled. This shared conceptualization is known as “ontology”. Among several ontology languages available, Web Ontology language (OWL) is the most widely used and accepted one. OWL is the ontology language of the Semantic Web. This research is aimed at deploying an OWL-based ontology for representing product manufacturing information and demonstrating an application of the deployed ontology in the manufacturing market framework. Manufacturing Market is a market in which manufacturing processes are the objects of trade. Digital Manufacturing Market is an Internet-based market that its demand (product) and supply (process) pools are populated by digital (ontological) descriptions of products and processes. To fulfill the manufacturing requirements of product, there should be a mapping between product and a set of processes which will form the supply chain of product. Given the huge number of processes in the supply pool of the Manufacturing Market, matchmaking between product and processes and formation of optimal supply chain would be a computationally intensive process. The problem becomes more difficult as the complexity of products increases. One promising approach to address this problem is automation. To enable automation, machine agents should be able to automatically process and integrate information. `` 35 Design and Manufacturing Robust Designated Component Analysis of Multiple Fixture Faults in Compliant Sheet Metal Assemblies Chino Imediegwu, S. Jack Hu cim@umich.edu, jackhu@umich.edu Products made of compliant sheet metals are widely used in the automotive, aerospace, and electronics industries. One of the paramount challenges for the assembly process of such compliant parts is the assembly dimensional variation which affect end product functionality, reliability and perceived quality. This is particularly true for compliant, non-rigid parts because clamping, joining and part fixture operations during assembly may introduce more dimensional variation as a result of deformation, springback phenomena and fixture error. To this effect, various methods for analyzing or diagnosing sources of dimensional variation have been developed with the aim of enabling quick detection and localization of assembly process faults based on inline dimensional measurements. Research activities in this area indicate that 70 percent of all dimensional faults in automotive manufacturing assembly occur as a result of fixture faults. Consequently, substantial fixture failure diagnosis with the potential to quickly detect and correct fixture faults can significantly improve overall build quality and enhance productivity. The integration of resources and methodologies have typically been effected on the front end of product development in scenarios characterized by complex products with complicated assembly processes such as the automotive industry. In such situations, manufacturing firms have employed sequential validation techniques to approve components, then subassemblies and finally the end product. This sequential process validation approach is typically characterized by increased costs due to rework and lengthened lead times. This research study seeks to improve designated component analysis as an analytical method and then use it to evaluate, quantify and correct dimensional variation in compliant sheet metal assemblies caused largely by fixture faults. This method can then be utilized to ensure a significant reduction in product validation time, cost and tool rework through out the assembly process. `` 36 Design and Manufacturing Design Microfiltration Compatible Metalworking Fluids via Transport Model Approach Fu Zhao, Andres Clarens, and Steven Skerlos fzhao@umich.edu Keywords: Metalworking fluids, microfiltration, design for environment, transport model Although metalworking fluids (MWFs) are widely used in machine tool industry as coolants and lubricants, they are inherently susceptible to microbial growth and contaminant accumulation which lead to potential occupational risks, deteriorated performance and significant cost and environmental burden due to frequently disposal. As a recycling process, microfiltration of MWFs has been shown to increase the longevity and quality of MWFs, and reduce the environmental and occupational health risks associated with MWF applications. Research is currently being performed to better understand the transport of MWFs through microfiltration membranes, including mechanisms of membrane fouling. In this paper, a mechanistic model previously developed by the authors is extended and utilized in the design of MWFs with higher flux. Three interdependent fouling mechanisms (i.e., pore constriction, pore blocking, and surface film formation) are mathematically modeled at the pore-scale to develop parameters that are meaningful to describe the relationship between MWF formulation and microfiltration flux. Specifically, pore constriction is mathematically modeled as a balance between adsorption and desorption parameters, and pore blockages are modeled in the context of queuing theory as a function of microemulsion particle size distribution and coalescence probabilities. After demonstrating the validity of the model, the model parameters are utilized as metrics to evaluate the impacts of different MWF formulations on flux. MWF formulation parameters considered here include oil type (mineral or vegetable), oil concentration, oil:emulsifier ratio, composition of emulsifier package, and hardwater ion concentration. It is shown that the model parameters can be reasonably estimated from empirical flux data, and that trends in these parameters can be utilized to formulate MWF microemulsions with slow coalescence rate, low surfactant adsorption, low adsorption/desorption equilibrium ratio, and smaller particle size. For the MWF microemulsions investigated in this paper, these characteristics are achieved by minimizing amounts of excess oil and surfactants, maintaining an oil:surfactant molar ratio of approximately 0.5, and by choosing emulsifier packages that result in microemulsions with greater repulsion between droplets. Moreover, it is shown that hardwater stable, vegetable-based, MWFs with high flux can be developed. Such formulations, in conjunction with microfiltration-based recycling, can be employed in manufacturing operations to significantly extend the useful life of MWF systems, while reducing their toxicity and life cycle greenhouse gas emissions. `` 37 Design and Manufacturing Swing Arm Design in Micro Internal Combustion Swing Engine (MICSE) Honghai Zhu and Professor Jun Ni honghai@umich.edu Keywords: List the keywords covered in your paper - optional. (Use Arial 11) A Micro Internal Combustion Swing Engine (MICSE) is a rotationally oscillating freepiston engine. A major design challenge in this kind of engine is the thermal seizure of the swing arm, which is called piston in traditional engines. Instead of using piston rings for combustion chamber sealing, a gap sealing mechanism is adopted in a MICSE. Due to the temperature difference between the swing arm and the engine core in the thermal steady state, the gap between them shrinks down to zero from the engine start-up state to steady state operation and finally evolutes to a thermal seizure, in the case of the swing arm and the engine core using the same material. Experimental observations verify the existence of thermal seizure after operating the MICSE for a few minutes. The objective of this research is to reduce the thermal efficiency loss due to leakage while avoiding thermal seizure. To have a good understanding of the thermal seizure problem, a steady state heat transfer finite element model is built in ALGOR FEA. Based on the analysis of the finite element model, an exact description of the differential thermal expansion can be obtained. Optimal geometry design and materials selection are proposed as the solutions to the problem. Experimental results verify these proposed solutions. `` 38 Design and Manufacturing Design for Products Embedded Disassembly Sequence Shingo Takeuchi and Professor Kazuhiro Saitou stakeuch@umich.edu Keywords: design for disassembly, design optimization, computer-aided design Due to the increased amount of abandoned products, reuse and recycling after the end of their useful life have been taken into consideration to not only conserve limited sources but also alleviate adverse environmental impacts such as air/water pollution and greenhouse gas emissions associated with materials production and manufacturing. Increased regulatory pressure is another motivation for reuse and recycling. For example, European Parliament passed the WEEE directive to regulate the material collection and appropriate End-Of-Life (EOL) treatment. Under these circumstances, the trend toward reuse and recycling motivated by regulatory and voluntary initiatives is increasing around the world, and consequently, manufacturers are becoming responsible for EOL treatments of their products. Design for Disassembly (DFD) is a design philosophy that intends to design and manufacture products so as to make the disassembly process easier. One of the main goals of DFD is to design products that can be disassembled along a disassembly sequence that maximizes the profitability of the entire disassembly process under environmental considerations and regulatory pressures. Products embedded disassembly sequence is introduced in our current research. The concept is to embed desired disassembly sequences inside a product during manufacturing and activate them at the disassembly process. To realize this concept, joint features that utilize geometric contacts between components are used to fix components instead of fasteners such as screws. A design methodology for products embedded disassembly sequence is proposed to embed a disassembly sequence inside a product. It takes as inputs a disassembly sequence and product components with their geometries, and produces optimal product configurations with joint features as Pareto optimal solutions. A multi-objective genetic algorithm with geometry-based crossover, coupled with products embedded disassembly sequence analyses is used to obtain Pareto optimal solutions to this problem, exhibiting trade-offs among functional constraints, joint feature cost and the embedment of a given disassembly sequence. `` 39 Design and Manufacturing Reliability Analysis for Nonnormal Distributions Using Multi-Level DOE Hyun Seok Choi, Sang Hoon Lee, and Byung Man Kwak hschoi@khp.kaist.ac.kr Keywords: Reliability analysis, Nonnormal Distribution, DOE(Design of Experiments), Level and Weight, Pearson system The main task of RBDO(Reliability based design optimization) is to obtain reliability efficiently and accurately, especially for structural systems which involves finite element analysis or mechanical systems with large number of random numbers. Various methods developed up to now such as first-order reliability method(FORM), second-order reliability method(SORM), Monte-Carlo simulation and experimental design techniques are still found not satisfactory for such applications. Experimental design technique is one popular choice and taken up in this article. Experimental design technique needs no derivatives and little computation as opposed to the Monte-Carlo simulation. The reliability analysis for nonnormal distributions using the three level DOE(design of Experiments) method was developed by Seo and Kwak in 2002. Although this method estimates only up to the first four moments(mean, standard deviation, skewness, and kurtosis) of the system response function, the results and the type of probability distribution determined by using the Pearson system are shown very good. However the accuracy is low in case of nonlinear performance function and sometimes, the level calculated is outside of the region in which the random variable is defined. In this article we suggest a modified three level DOE method to overcome these weaknesses and to obtain optimum choice for 3 levels and weights to handle nonnormal distributions. Furthermore we extend it to finding the optimum choice for 5 levels and weights to increase the accuracy in case of nonlinear performance function. A systematic procedure for reliability analysis is then proposed by using the Pearson system. The proposed procedure of reliability analysis is applied to several examples containing various nonnormal distributions. This shows that the proposed method is practicable with very good accuracy and efficiency, regardless of the type of distributions. `` 40 Design and Manufacturing Design of heat-reversible snap fits for space frame bodies Mohammed Shalaby and Dr. Kazuhiro Saitou mshalaby@umich.edu Keywords: Snap-fit design, genetic algorithms, design for disassembly Recent legislative efforts to reduce the environmental impacts of the entire life cycle of the next generation automotive body structures, aluminum space frame bodies, have increased the need for non-destructive and standard means of the separation of external body panels from structural frames. Aluminum space frame bodies are considered to be the next generation body structures due to its lightweight and improved rigidity; they are also environmentally sound due to the improved fuel efficiency owing to its lightweight. One of the challenges in improving the recyclability of an aluminum space frame body structure is the clean separation of incompatible alloys used in various body components, in particular, extruded structural beams and stamped external panels. In the current aluminum space frame bodies, joining between the extruded beams and stamped external panels is achieved using permanent joints such as self-piercing rivets and resistance spot-welding. These permanent joints can only be detached destructively, inevitably leaving residues of mating materials that prevent the “closed loop” recycling of aluminum alloys. It is essential, therefore, to develop a joining method that allows easy, non-destructive detaching at a desired time. In this research, the use of heat actuated reversible snap fits for car frame/panel assembly is proposed. Snap-fit is a preferred joining method because: no need of separate fasteners, easily assembled, can be disassembleable, reduces overall product cost and makes the recycling process more economic, and provides clean separation between frame and panel. In the first stage, different designs of a joint (snap fit) shape, dimensions and location on the panel for the disassembly process are analyzed using flat and square panel model. In the second stage, the optimum location of these snaps on an automotive fender model, meeting certain NVH requirements, is found using genetic algorithms. The snaps are modeled as spring elements with stiffnesses obtained from the square panel model. ABAQUS is used to find the fender natural frequencies and their corresponding mode shapes. `` 41 Design and Manufacturing Customer Demand Satisfaction in Production Systems: Random Correlated Demand Case Rahul R. Bagdia and Semyon M. Meerkov rbagdia@umich.edu, smm@eecs.umich.edu Keywords: end-to-end performance metric, customer demand satisfaction, due-time performance, random correlated demand, finished good buffer, Markovian demand A randomly demand-subjected Production – Inventory - Customer (PIC) system is analyzed for calculating an appropriate end-to-end performance metric of the overall system. This performance metric expresses the (prob)ability of the system to meet random customer demand and is termed as the Due-Time Performance (DTP) measure. There exist other suggested performance measures like production rate, average inventory and production variance, which are significant and still pose computational challenges. But all of them isolate the main driving force for any production system – the “demand” or the “customer”, whose quality and timely satisfaction will finally govern the plant economy. The considered serial-assembly production system is characterized by unreliable machines (with random up and down times), finite intermediate and finished good buffering and correlated Markovian demands. The suggested analytical DTP calculation is made when the system reaches the steady state (or stationary distribution in stochastic sense) under two machine reliability models namely – Bernoulli and Exponential. An analytical method for calculating DTP of a one machine production line is developed first, followed by an iterative algorithmic extension for a more general case of M machines serial line. The study aims in bringing out the effect of the correlation amongst demands on the overall system performance (including DTP and inventory) and is an extension of previously reported work for random but IID (Independent and Identically Distributed) demands. A novel comparison between the DTP of a production system, subjected to Markovian and IID demand models is established, and a parameterization of the correlation structure is suggested. This parameterization makes possible to study various marketing control strategies to influence the correlation pattern between the demands to raise the DTP and simultaneously lower the inventories. At the same time, the analysis supports optimal decision making for buffer capacities and negotiating shipment period with the customers for a desired high DTP. `` 42 Design and Manufacturing Vehicle Crashworthiness Design via Equivalent Mechanisms and Crash Mode Matching Karim Hamza and Professor Kazuhiro Saitou khamza@engin.umich.edu Design of vehicle structures in order to achieve good crashworthiness is highly desirable yet difficult task that faces vehicle designers. Driven by ethical responsibility, government regulations and market competitiveness, vehicle designers strive to increase the safety of their vehicles while maintaining cost efficiency. Unfortunately, design for crashworthiness is a difficult and expensive task. The best designs are not always obvious, for example, increasing the stiffness of the structure makes it strong but may decrease the crash energy absorption thereby degrading the vehicle safety. It is crucial to have thorough understanding of the pros and cons of design decisions in order to improve vehicle crashworthiness. Existing tools for analysis fall under three broad categories: i) experimental testing, ii) nonlinear finite element (FE) simulations and iii) surrogate (approximate) models. Experimental crash testing is very expensive and is rarely used except in limited studies and final tests for vehicle certification. Nonlinear FE simulations using detailed models provide good prediction of vehicle performance during crash. However nonlinear FE simulations consume enormous computational resources and their results are often confounded by numerical noise. Therefore designers often resort to approximation techniques in conjunction with the detailed FE models. Different types of surrogate models have been used in the literature in order to aid designers in their task. The two major categories of such models are: i) abstracted functional approximations such as polynomial response surface and neural networks and ii) physical approximate models such as lumped masses connected by springs. The current research is dedicated to developing better physical approximate models that avoid extra abstraction and allow for recapturing the essence of the crash phenomenon. This research models the collapse of the vehicle structure during crash using equivalent mechanisms composed of rigid masses connected by prismatic and revolute joints that have special nonlinear springs, which are tuned to mimic the behavior of collapsing structural members. The proposed modeling scheme offers physically sound approximation that retains the gross behavior (or crash modes) of real vehicle structures. Preliminary results show success in providing insightful guidance to improving suboptimal designs at a vastly reduced computational effort compared to direct optimization approaches. `` 43 Design and Manufacturing Control of the Assembly Process Luis E. Izquierdo, S. Jack Hu (Use Arial 14) leiv@umich.edu Keywords: Compliant and rigid body assembly corrections, Variation reduction and Programmable tooling. Traditionally to improve the product quality, manufacturing engineers concentrate there effort on robust design to prevent variation (i.e. using slip planes), and production engineers in variation diagnosis and corrections. A new approach has emerged based on the use of programmable or adaptive tooling. This tool was originally introduced in the assembly lines to increase the flexibility (assemble different type of products in the same assembly line). Now using programmable tooling is possible to adjust locators and clamps on a part by part basis, doing so, the assembly variation could be diminish, and the process could remain in control (Statistical Process Control SPC definition of in control). The question that emerges now is: how to correct the part in order to reduce the final variation. There are two main approaches, the first considering that the parts are rigid bodies, and the second considering that they are compliant or deformable parts. In the rigid body case, the variation due to the part or tooling is corrected by measuring the parts position before they are assembled together. Then the correction is calculated based on the deviation from nominal position, and finally the rectification is applied. In the case of compliant parts the strategy is the same, but the way to determine the correction is different due to the nature of the parts. This presentation introduces a method to determine the assembly correction of complaints parts, and doing so remain in the in control state. The method is based on an accurate model of the assembly process, the parts (using FEM) and the capabilities of the programmable tooling. The modeling is crucial because in complaints there are infinite possible variations of the parts by deformations. Then the most common or important variations have to be analyzed, and the necessary corrections have to be study for that specific variation to achieve almost zero variation of the final assembly. In a real case combining the modeling results with in line measurements on the assembly station pre and after-assembly the correction could be accurately specified for every part. A case of study present the capability of this process in which a combination of compliant and rigid body corrections could achieve a perfect assembly. `` 44 Design and Manufacturing Preference Coordination in Engineering Design Decision-Making Jeremy Michalek, Fred Feinberg, and Panos Papalambros michalek@umich.edu Keywords: Preference Coordination, Analytical Target Cascading, Design Optimization, Discrete Choice Analysis, Logit Design optimization methodologies offer assistance to engineers in achieving product performance objectives; however, in practice most design problems involve tradeoffs among a set of competing objectives such as performance, cost, and marketability. It remains an open question: “How can a designer best navigate these tradeoffs to select the most preferred design, particularly when social and economic preferences conflict with user preferences and the user population itself is diverse?” Preference coordination draws upon the rich literatures in marketing, economics, and psychology to model preference structures of individuals and groups and coordinate these preferences with design models of engineering performance. The rigorous coordination of these models assists the designer in making tradeoff decisions by providing usable information about consumer preferences for product characteristics and price, economic preferences of the producer, and societal preferences such as reduced environmental impact. Use of preference coordination is demonstrated to improve profitability substantially relative to disjoint decision-making. When coupled with models of heterogeneous consumer preferences, manufacturing systems, and public policy models, it can be used to design product lines and to study the effects of regulation policy on design decisions for navigating the tradeoff between private and public preferences. This talk focuses specifically on the coordination of marketing and engineering models for decision-making in product development. Marketing and engineering design decisions are typically treated as separate tasks both in the academic literature and in industrial practice, and their interdisciplinary interactions are not well-defined. In this article, analytical target cascading (ATC), a hierarchical optimization methodology, is used to frame a formal optimization model that links marketing and engineering design decisionmaking models by defining and coordinating interactions between the two. For complex products, engineering constraints typically restrict the ability to achieve some desirable combinations of product characteristic targets, and the ATC process acts to guide marketing in setting achievable targets while designing feasible products that meet those targets. The method is demonstrated in the design of dial-readout household scales, using real conjoint choice data and a parametric engineering product design model. Results indicate that the most profitable achievable product can fall short of predictions based on marketing alone, but well ahead of what engineering may produce based on original marketing target specifications. `` 45 Design and Manufacturing Development of a CAD-based General Purpose Optimal Design System and Its Application to Structural Shape for Fatigue Life Yonggyun Yu and Professor Byung Man Kwak ykyou@khp.kaist.ac.kr Keywords: optimization, CAD based, CORBA, Open I-DEAS, I-DEAS An integrated optimal design software system for structural components has been developed, interfacing existing commercial codes for CAD, CAE and Optimization. Various previously developed software systems for optimal design have been analyzed in terms of modularity and independence of analysis activities, flexibility of optimal design formulation, user convenience and so on. They include specialized optimal design software codes, optimization module imbedded in CAD software developed by CAD developers, and optimal design software systems based on API of commercial CAD software. The advantages of the CAD imbedded optimal design approach and those of specialized optimal design software are taken to develop the system. A user can define his optimal design problem in the user interface for problem definition in the CAD control stage, where design variables are directly selectable from the CAD model and various properties and performance functions defined. The commercial CAD API codes, Open I-DEAS is used for the development. The resulting software is minimally connected to CAD and CAE systems while keeping maximum independence from each other. This assures flexibility and freedom for problem definition. Fatigue life optimization is selected as a nontrivial application area. For stress history and life calculation, ABAQUS and Fe-Safe are used and interfaced. As a specific example, the shape design of a knuckle part of an automobile is performed, where the minimum fatigue life over the material domain in terms of the number of cycles of a curb strike are maximized under the constraint of not exceeding the current mass. The fatigue life has been improved four times the initial life. The developed software is shown to maintain the advantages of existing optimal design software systems while improving independency and flexibility. `` 46 Design and Manufacturing Manipulation of Micro/Nano Particle using Nanotweezer Junsok Lee and Professor Soohyun Kim jameslee@kaist.ac.kr Keywords: CNT arm, Nanotweezer, Electrochemical etching, Length control There have been many research results about the nanotweezer using carbon nanotube because of its superior mechanical and electrical properties to the conventional material. But, it is very difficult to find out the carbon nanotube having proper length for nanotweezer and to attach a carbon nanotube on the substrate. In this research, a new method is proposed to make a CNT(carbon nanotube) arm and to control its length for a nanotweezer which can handle a sub-micrometer sized particle. And also, it is shown to attach a particle using the nanotweezer which was made by the tungsten tip and carbon nanotube. The electrochemical etching method was used to control the length of the CNT arm by cutting the carbon nanotube with arbitrary length and it is possible to monitor the process through the current measurement. And also, we can enhance the fixation strength of the carbon nanotube on the substrate with the current during the cutting process. We can calculate the etch rate of the carbon nanotube from the etched volume and the amount of applied charge. The carbon nanotube is successfully cut using this method in a CNT arm of a nanotweezer The nanotweezer is composed of two CNT arms and macro actuators such as a piezo actuator. The attaching action of a particle is done under the direct view of an optical microscope with the nanotweezer. We use a sub- m sized particle for the target particle which is placed on a target particle holder. Since the diameter of the carbon nanotube is about 100 nm , the overall process is done under the circumstance of an optical microscope. Compared with the previous researches about the nanotweezer, the separated substrate of the nanotweezer, which is proposed in this research, has some advantages as followings. It is possible to grip large particle because the gripping range of nanotweezer is not confined due to the macro actuators. It is possible to use conducting material as the substrate of nanotweezer and it is not necessary to deposit additional electrodes on the substrate. `` 47 Fluid Mechanics, Heat Transfer and Combustion The Development of a Low-NOx, Low-Soot Diesel Engine Combustion Strategy Timothy Jacobs and Prof. Dennis Assanis tjjacobs@engin.umich.edu Keywords: NOx-Soot Reduction, Diesel Premixed Combustion Increased consumer demand for fuel efficient, low-polluting vehicles motivates automobile manufacturers to explore the use of diesel engines as the primary power source. The demand for fuel efficiency is satisfied by the lean combustion strategy, the good fit for turbocharging, and the use of a high compression ratio in a diesel engine. However, the heterogeneous mixture of a diesel engine creates challenges for satisfying the demand of a low-polluting vehicle. The following presentation outlines the use of new electronic technology to trigger low-soot and low-NOx combustion strategies in a diesel engine, while still surpassing gasoline fuel efficiencies. The new electronic technology enables key design parameters such as variable fuel injection pressure, variable manifold boost pressure, and variable exhaust gas recirculation rates. These key parameters provide opportunities for simultaneous reductions in soot and NOx by attaining fully premixed combustion, and avoiding the high-polluting diffusion phase of combustion. The use of high injection pressure to quickly inject fuel, an advanced injection timing to ensure proper time for mixing and evaporation, and a high EGR rate to inhibit the chemical energy release all assist in achieving premixed compression ignition combustion, and soot and NOx emissions that meet upcoming federal emission regulations. `` 48 Fluid Mechanics, Heat Transfer, and Combustion The Impact of Fuel Injection Pressure on the Combustion, Emissions, and Performance of a Medium-Duty Diesel Engine Jonathan Hagena, Christos Chryssakis and Professor Dennis Assanis jhagena@umich.edu Increasingly stringent emissions standards are forcing modern diesel engines to produce fewer emissions than their predecessors. To meet these challenges, engine manufacturers have developed highly advanced fuel injection hardware and software that precisely controls the characteristics of the injection event. As the flexibility of these systems increases, so does the complexity of utilizing them optimally at all engine operating conditions. Thus a comprehensive understanding of the influence of fuel injection parameters on diesel combustion is necessary. This work explores the impact of fuel injection pressure on the combustion, emissions, and performance of a medium duty diesel engine. The focus of this investigation is primarily experimental in nature, but also uses numerical tools to aid in the explanation of observed data trends. Experiments were conducted on a 6.0 L V-8 diesel engine equipped with combustion diagnostic and emissions instrumentation. Numerical studies are conducted with KIVA-3V, a multi-dimensional computation fluid dynamics simulation. This tool generated spatially and temporally resolved temperature and equivalence ratio data to provide insight into the combustion process. Injection pressure was found to significantly impact combustion and emissions, while having a lesser effect on performance. Higher injection pressures speed up the rate at which fuel is prepared for combustion, thereby increasing cylinder pressure and the rate of heat release. This leads to increased combustion noise; tripling the injection pressure augments the engine noise by a factor of 7.7. Carbon monoxide emissions drop by a factor of 1.8, while hydrocarbon emissions increase 1.7 times. The same injection pressure increase causes NOX emissions to rise by a factor of 2.4 and soot emissions to decrease 35.5 times. Engine performance trends with injection pressure are dependent upon engine operating condition, but no differences greater than 8% are observed in fuel consumption. `` 49 Fluid Mechanics, Heat Transfer and Combustion Dual-Use Engine Calibration: Leveraging Modern Technologies to Improve Performance-Emission Tradeoffs Alexander Knafl, Dr. Zoran Filipi, Prof. Dennis Assanis aknafl@umich.edu Keywords: Diesel Engine, Fuel Efficiency (BSFC), Nitric Oxides (NOx), Soot, Engine Control Strategy, Injection Timing, Split Injection Modern diesel engines manufactured for production vehicle purposes are calibrated to meet EPA emissions regulations. Many of the technologies and strategies typically incorporated to meet these emissions targets compromise engine performance and efficiency. As an example, injection timing strategy is usually very much dictated by the need to limit the nitric oxide emissions rather than maximum efficiency. However, new emissions-reduction technologies offer more flexibility and therefore could be used to enhance engine performance and efficiency, while still keeping the emissions within tolerable limits. Thus, this paper explores the performance-emissions tradeoffs on a modern medium duty diesel engine and uses the newly acquired insight to propose dual use strategies, e.g. a performance oriented injection timing schedule required for military applications augmented with an advanced multiple injection strategy that minimizes the emissions penalty. A study was conducted on a production, medium-duty International V8 Diesel engine. The engine was run over an AVL 8-Mode steady state test using the production calibration and an optimized control scheme for power and efficiency. It was shown that by properly controlling the engine’s fueling strategy and disabling the production exhaust gas recirculation (EGR), significant improvements in power and efficiency were realized. For the power optimized calibration scheme, lower levels of total hydrocarbon (THC), carbon monoxide (CO) and particulate matter (PM) emissions were obtained, while nitric oxide (NOx) emissions increased. `` 50 Fluid Mechanics, Heat Transfer and Combustion A Fully Integrated CFD and Multi-zone Model with Detailed Chemical Kinetics for the Simulation of HCCI Engines Aristotelis Babajimopoulos and Professor Dennis Assanis ababajim@umich.edu Keywords: HCCI, CFD, Combustion, Chemical Kinetics, Mixing Temperature gradients present in an engine cylinder due to heat transfer to the cylinder walls have a great impact on the combustion process in the Homogeneous Charge Compression Ignition (HCCI) class of engines. Numerical models have been able to accurately capture these temperature effects on the combustion process for homogeneous mixtures. However, to facilitate control and higher power density, some researchers have deviated from truly homogeneous mixtures and looked to more elaborate ways of mixture formation, such as Variable Valve Actuation (VVA) or Direct Injection. These techniques can introduce significant composition stratification in addition to temperature stratification in these engines. Modeling of this process becomes much more complicated because both mixing and chemistry must be handled in a computationally efficient way. A modeling approach that fully integrates a CFD code (KIVA-3V) with a multi-zone model with detailed chemical kinetics is introduced. At each computational timestep, a multi-zone model provides the KIVA-3V with the necessary energy source terms for each cell, by solving the detailed chemical kinetics for groups of cells (zones) with similar properties. The methodology is an extension of previous work in that it can now account for both temperature and equivalence ratio (composition) gradients in the cylinder throughout the whole cycle. In this direction, a method of tracking down the equivalence ratio in each cell during combustion is introduced. One important consideration is how to actually define equivalence ratio to adequately capture the spatial composition field throughout the cycle. Validation cases were developed by solving the detailed chemistry in every cell of a KIVA-3V grid. This allowed the validation of the chemistry model alone, isolating the chemistry model from other KIVA-3V submodels. The methodology was tested for several cases with varying initial temperature and equivalence ratio distributions, showing good agreement with the detailed solutions, while providing further insight into the effect of equivalence ratio distribution on ignition, burn duration and emissions in an HCCI engine. `` 51 Fluid Mechanics, Heat Transfer and Combustion Transient Spray Cone Angles in Pressure-swirl Injector Sprays Jordan A. Snyder, Ronald O. Grover, Jr., Professor Volker Sick and Professor Dennis Assanis janyder@engin.umich.edu, rgrover@engin.umich.edu Keywords: sprays, pressure-swirl, nozzle fluctuations The transient cone angle of pressure swirl sprays from injectors intended for use in gasoline direct injection engines was measured from 2D Mie scattering images. A variety of injectors with varying nominal cone angle and flow rate were investigated. The general cone angle behavior was found to correlate well qualitatively with the measured fuel line pressure and was affected by the different injector specifications. Experimentally measured modulations in cone angle and injection pressure were forced on a comprehensive spray simulation to understand the sensitivity of pulsating injector boundary conditions on general spray structure. Ignoring the nozzle fluctuations led to a computed spray shape that inadequately replicated the experimental images; hence, demonstrating the importance of quantifying the injector boundary conditions when characterizing a spray using high-fidelity simulation tools. `` 52 Fluid Mechanics, Heat Transfer and Combustion Modeling of Porous Filter Permeability via Image-Based Stochastic Reconstruction Fu Zhao and Professor Steven J. Skerlos fzhao@umich.edu Keywords: permeability, porous filter, stochastic reconstruction, image To facilitate design of porous filtration system that are widely used in environmental engineering and pollution prevention applications, it is highly desirable to have a model that can estimate filter permeability based on filter characteristics. The current approach relies heavily on empirical models using only bulk properties with parameters calibrated based on time consuming experiments. It is well known that transport properties of porous media can not be predicted without including pore-scale physics. Previous research has indicated that it is possible to predict permeability of isotropic geophysical porous media through a network model approach. This research develops a methodology for producing a pore-scale, 3D computational network model of porous filter permeability that is based only on the analysis of 2D images of the filter matrix (e.g., acquired from photography or electron microscopy) and first principles. The computationally reconstructed porous filter model retains statistical details of porosity and its spatial correlations within the filter, and can be used to calculate permeability for either isotropic or 1D anisotropic porous filters. In the isotropic case, validation of the methodology was conducted using 0.2μm and 0.8μm ceramic membrane filters, for which it is shown that the image-based computational models provide a viable statistical reproduction of actual porosity characteristics. It is shown that these models can predict water flux directly from first principles with deviations from experimental measurements on the order of experimental error. In the anisotropic case, validation of the methodology was conducted using a natural river sand filter. For this case, it is shown that the methodology yields predictions of filtration velocity that are similar or better than predictions offered by existing filtration models, while not requiring experimentally determined coefficients. It was found for the sand filter that the deviation between observation and prediction (approximately 20%) was largely due to swelling during image preparation, which can likely be reduced using methods reported in the literature. Based on these results, it is concluded that the computational reconstruction methodology is valid for porous filter modeling, and given that it captures pore-scale details, it has potential applications in the investigation of permeability decline under the influence of pore-scale fouling mechanisms. `` 53 Fluid Mechanics, Heat Transfer and Combustion Direct modeling support to the development of compact fuel processor systems for PEM fuel cell application Amit Dhingra and Professor Hong G. Im dhingraa@umich.edu Keywords: fuel processor, microscale, hydrocarbon reforming, modeling In the new millennium, there is strong research interest in the development of power generation devices based on hydrogen and other hydrocarbons. This stems from the fact that the power density of hydrocarbons is up to 100 times more than conventional batteries. Hydrogen also has a much better efficiency and emission performance. Applications of these small micro power generators will be prominent in portable and mobile devices such as cell phones, laptops, PDA’s etc. However numerous problems are faced by these micro-scale heat devices. Reduction in size leads gives rise to heat loss from the increased surface to volume ratio. Thus these devices need to be designed as compact, integrated and heat efficient packages. This presentation is an overview of how modeling provided direct support and guidance to the design of the U of M micro-fuel processor system. Modeling of a fuel processor was approached by two interlinked paths: detailed modeling of individual component and the system integration. Details of both approaches will be discussed. Even though modeling cannot replace experimentation as a primary method to obtain performance data, it will be demonstrated that modeling helped reduce the design time and costs of the complete design process appreciably. A brief account on the modeling results and design challenges will be discussed. Strategies for alternates designs and improving the current one will be presented as well. `` 54 Fluid Mechanics, Heat Transfer and Combustion A Computational Study of Catalytically Assisted Combustion in a Stagnation Point Flow Jingjing Li and Hong G. Im jingjinz@umich.edu Keywords: computational combustion, catalytic reaction, stagnation flow Combustion is an interdisciplinary science involving a wide range of length and time scales associated with chemistry and transport processes. In traditional macro-scale combustors, accurate description within combustion devices relies heavily on turbulence and reaction term closure at the scales smaller than numerical resolution. Except for some specialized applications, the effects of wall heat transfer and surface reaction have been usually considered secondary effects in macro-scale combustion. While studying microcombustors may seem simpler for its smaller dimension, the increased surface-to-volume ratio also implies that the surface heat transfer and chemical reaction are no longer negligible. In the gas-phase premixed combustion, it has been well known that there exists a minimum physical critical dimension (such as the gap size), called the quenching distance. Due to the large surface-to-volume ratio, a substantial amount of heat loss to the surface is expected in micro-combustors. Therefore, it is desirable to extend these limits to enhance the operating range and overall combustion efficiency. A natural choice is to utilize the catalytic reaction at the surface. Recently, chemical kinetic models involving simple gaseous fuels on platinum or palladium surface have been developed by elementary reactions on a molecular level, described into modified Arrhenius equation forms including additional surface coverage dependence. It may be expected that the existing kinetic data that have been validated against experimental results can be extended in the micro-scale combustion studies without significant loss of accuracy. To gain fundamental understanding of physical and chemical characteristics in microcombustors, in the present study numerical simulations are performed in a stagnationpoint flow combustor. The combustible mixture of methane and air is blown on the top of the catalytic platinum made surface, forming a classical stagnation-point flow configuration. This geometry represents a classical problem of combined heterogeneous/homogeneous combustion subjected to flow straining, which is a key parameter that governs the quenching and flammability limit. A one-dimensional similarity formulation is derived with full consideration of detailed surface and gas-phase chemical kinetic models. Parametric studies are conducted to investigate the effects of inlet fuel velocity, equivalence ratio, heat loss on the combustion and extinction modes. The results show that the presence of catalytic surface in general extends the range of mixture flammability. Bifurcations between detached and attached flame regimes are also observed, which may have a significant impact when the behavior is coupled with unsteady oscillatory operating conditions. The results are expected to provide insight into improving the overall combustion stability and efficiency of micro-combustors. `` 55 Fluid Mechanics, Heat Transfer and Combustion Numerical modeling of radiative extinction of spherical diffusion flames under microgravity conditions Songtao Tang, Ramanan Sankaran and Hong G. Im tangst@engin.umich.edu, hgim@umich.edu Keywords: spherical diffusion flame, microgravity, radiation The presence of buoyancy influences the characteristics of diffusion flames, mostly because it modifies and complicates the convective diffusive transport processes which affect the transport of thermal energy and reactants to and from the chemical reaction zones. In addition, gravity introduces a degree of asymmetry into an otherwise symmetric phenomenon. Microgravity environment furthest excludes impacts beyond combustion; therefore a reasonable comprehension of flame characteristics in microgravity condition will largely help us understand the essence of combustion process. Moreover, fire safety is a major concern in spacecraft running processes, understanding of the quenching mechanism of microgravity flames helps to improve fire safety in spacecrafts. In this study, a one-dimensional spherical model is set up to study the transient ignition, combustion, and extinction process for highly radiating diffusion flames. Detailed chemical kinetic rates and transport properties are incorporated through the CHEMKIN and TRANSPORT packages, and a Newton iteration scheme via the TWOPNT module is used to obtain the steady solution of the boundary value problems. A stiff differentialalgebraic equations solver, DASPK, is also employed to find the transient flame dynamics. In addition, a radiation model is applied and properly modified to study the quenching mechanism of flames. Some preliminary results are presented and compared with experimental measurements. `` 56 Fluid Mechanics, Heat Transfer and Combustion Flow and Heat Transfer Analysis for the Performance Improvement of Cross-Flow Fin-Tube Heat Exchangers Cheensu An and Professor Dohyung Choi ancheensu@kaist.ac.kr Keywords: porous medium model, heat exchanger, computational fluid dynamics The flow and the heat transfer about the cross-flow fin-tube heat exchanger in an outdoor unit of a heat pump system has been numerically investigated. Using the general purpose analysis code, FLUENT, the Navier-Stokes equations and the energy equation are solved for the three dimensional computation domain that encompasses multiple rows of the fin-tube. The temperature on the fin and tube surface is assumed constant but compensated later through the fin efficiency when predicting the heat-transfer rate. The contact resistance is also taken into consideration. The flow and temperature fields for a wide range of inlet velocity and fin-tube arrangements are examined and the results are presented in the thesis. The details of the flow are very well captured and the heat transfer rate for a range of inlet velocity is in excellent agreement with the measured data. The flow solution provides the effective permeability and the inertial resistance factor of the heat exchanger if the exchanger were to be approximated by the porous medium. This information is essential in carrying out the global flow field calculation which, in turn, provides the inlet velocity for the microscopic temperature-field calculation of the heat exchanger unit. `` 57 Fluid Mechanics, Heat Transfer and Combustion Thermal management of Slab-Coupled Optical Waveguide Lasers (SCOWL) Kwok Leung Chan and Kevin Pipe klchan@umich.edu Keywords: microscale, semiconductor laser, temperature, heat transfer Temperature control of semiconductor lasers is important for device stability and efficiency; carrier leakage and wavelength drift occur at high operating temperatures. In this experiment, a 20m microthermocouple with 10mK accuracy is used to measure the top and bottom surface temperatures of the laser under various operating currents and optical outputs. The relation between the optical output and the temperature of the laser is investigated. Femlab models are used to verify the measurements and predict the importance of heat transfer by convection and radiation. The causes of surface temperature variation are investigated. Fig.1 - 2 thermocouples are placing on the laser ridge map of Femlab model Fig.3 – Top and bottom surface temperatures VS current `` 58 Fig.2 – Temperature Fluid Mechanics, Heat Transfer and Combustion Temperature-Dependent Luminescence Quenching in Random Nano Porous Media Xiulin Ruan and Professor Massoud Kaviany xruan@umich.edu Thermo-Optical bistability is a phenomenon in which certain parameters of a nonlinear system have two or more stable states for some particular inputs, caused by the temperature dependence of the optical properties, such as the absorption coefficient and the luminescence quantum yield. Bistability has its applications in optical communication (e.g., all-optical switches), optical computation (e.g., memories, logic systems), and compact solid state lasers. Previously, thermo-optical bistability has been treated using a macroscopic, lumped energy conservation equation. In this study, the intrinsic thermo-optical bistability in the luminescence of a random, crystalline nanopowder doped with rare-earth elements, is analyzed at the microscopic level, by considering the transport, transition, and interaction of the basic energy carriers. The four fundamental governing equations (Liouville equation for electrons, Boltzmann Transport Equation for photons and phonons, and energy conservation equation for combined carriers) are used, and the carrier interaction processes are developed, with the temperature identified as the critical variable. Particularly, the multiphonon relaxation process is highly temperature dependent, resulting in a luminescence quantum yield as a nonlinear function of temperature. Additionally, the thermal conductivity is strongly temperature dependent, enhancing the nonlinearity. The set of equations are solved first using the effective medium treatment (equation of radiative transfer), yielding the one-dimensional, coupled intensity and temperature distributions in the nanopowder. The luminescence quenching and temperature jump (due to the positive feedback of temperature), occurring with the increase (or decrease) of the irradiation, are predicted. Although weakened by conduction, the spatial nonlinearities of temperature, such as a large local temperature gradient, is also predicted. To evaluate the validity of the effective medium treatment (a particle treatment), the coherent wave treatment (Maxwell’s equations) is also made. The same set of equations, in which the BTE for photons is replaced by the Maxwell’s equations, are again solved for a one-dimensional geometry. Then the nonlinear effects (bistability and field enhancement) are predicted. The results of this direct simulation is compared with the effective medium treatment. The predicted results for the luminescence bistability are in good agreement with the available and ongoing experiments. `` 59 Solid Mechanics and Materials Fast Speed Expansion Technique For The Transient Analysis Of Automotive Clutches Jiayin Li and James R. Barber jiayinl@engin.umich.edu Upon clutch application, the steel disks are squeezed against the friction disks by hydraulic pressure. Rotational speed of the steel disks is produced by friction between the steel and friction disks. The overwhelming majority of the frictional energy is converted to heat. Because the heat generation is non-uniform, it produces non-uniform deformations in disks. These deformations affect the contact pressure distribution, which, in turn, further affects the temperature distribution. Hence, a feedback process is established. When a particular sliding speed, called the `Critical Speed', is exceeded, this feedback process becomes instable, due to at least one of real part of the eigenvalues is positive. This phenomenon is known as thermoelastic instability (TEI). Yi developed custom software, named `Hotspotter', using the finite element method to solve the critical speed of each model. However, `Hotspotter' assumes that the sliding speed is constant, whereas the actual engagement takes place at variable sliding speed, which probably is higher than the critical speed initially, but falls below it finally. Because engagement occurs over a very short period of time, detrimental high local temperatures may not be developed before the sliding speed has fallen below the critical value. Therefore, it is necessary to solve the transient behavior of the thermoelastic contact problem. For a large-scale problem, transient simulation is extremely time-consuming. AlShabibi and Barber has developed a reduced order model by using a truncated eigenfunction expansion to represent the temperature. The truncated eigenfunction series contain only those terms corresponding to several dominant eigenvalues. However, when the sliding speed falls below the critical speed, the eigenvalues tend to cluster together and no subset can be regarded as dominant. At same time, all of the real parts of the eigenvalues are negative and the stiffness ratio is large, in other words, the system is stiff. Thus, it is also hard to solve the ITTEC problem by traditional numerical methods when the sliding speed is below the critical speed. Zagrodzki has developed transient modal analysis method (TMA) to solve the ITTEC problem for the whole speed range. In the TMA method, the transient nodal temperatures are expressed in modal coordinates, corresponding to the eigenfunctions of the corresponding homogeneous (unloaded) problem. However, for the large-scale ITTEC problem, this method is time-consuming, too. To overcome this difficulty, we propose a new method based on the asymptotic waveform evaluation (AWE). This method is referred to as fast speed expansion (FSE). With the known eigenvalues and eigenfunctions at a limited number of sparsely speeds, the FSE technique employs an efficient algorithm to interpolate and expand the eigenfunctions and eigenvalues over a speed band. Consequently, the FSE method can greatly reduce the transient problem computational time by dramatically reducing the number of full eigenvalue solutions required. `` 60 Solid Mechanics and Materials Stress Fields in Accreted Planetary Bodies Jon Kadisha and Professors Jim Barbera and Pete Washabaughb jkadish@engin.umich.edu Keywords: Accretion, Asteroids, Comets, Moving Boundary, Residual Stress Studying the stress fields of planetary bodies provides insight into their internal properties and mechanisms for evolution. The stress fields of the terrestrial planets (Mercury, Venus, Earth, and Mars), asteroids, and comets cannot be accurately characterized using the typical elasticity analysis because these objects formed by accretion (Weidenschilling 1997, 2000). During the accretion process, the object grows by the continual deposition of particles onto its surface. As each layer of particles is deposited on the surface, it loads and deforms the underlying material such that subsequent layers are applied to an object that has a non-zero stress field. This non-zero stress field, also called the residual stress, is present for all time such that if all tractions and body forces were removed from the body, it would still be in a state of stress. The analytical solution of a self-gravitating, accreted sphere with zero tractions whose spin rate is allowed to vary during its growth is derived using small deformation theory. The stress field of such an object consists of an inelastic component that is constant in time (residual stresses) and a time varying, elastic component. Both must satisfy equilibrium, but only the latter has to satisfy compatibility. The additional degrees of freedom needed to solve for the residual stress field come from the accretion process itself. The process dictates that not only must the surface be traction free, but also that all six stress components must equal zero at the sphere’s surface. This stress field is qualitatively different from that of a non-accreted body determined using the usual elasticity analysis and is illustrated by comparing the failure mechanisms of the two bodies. In an accreted body, the gravitational stresses are hydrostatic implying that failure is strictly a result of centrifugal forces arising from the object’s spin. In a non-accreted body, the gravitational stresses are not hydrostatic and are significant in determining failure with the rotational stresses actually reducing the tendency for disruption. These differences result in higher effective strengths for accreted bodies than non-accreted bodies. References Weidenschilling, S.J. 2000. Formation of Planetesimals and Accretion of the Terrestrial Planets, Space Science Reviews 92, 295-310. Weidenschilling, S.J. 1997. The Origin of Comets in the Solar Nebula: A Unified Model, Icarus 127, 290-306. a b Department of Mechanical Engineering Department of Aerospace Engineering `` 61 Solid Mechanics and Materials Frequency Drops in Resonant Bending Fatigue Tests of Notched Crankshaft Sections Kyoo-Sil Choi and Professor Jwo Pan ckyoosil@engin.umich.edu Keywords: Resonant frequency, Fatigue test, Notch depth Resonant frequencies of a resonant bending system with notched crankshaft sections are obtained experimentally and numerically in order to investigate the effect of notch depth on the drop of the resonant frequency of the system. Notches with the depths ranging from 1 to 5 mm, machined by an EDM (Electrical-Discharging Machining) system, were introduced in crankshaft sections at the fillet between the main crank pin and crank cheek. The resonant frequencies of the resonant bending system with the crankshaft sections with various notch depths were first obtained from the experiments. Threedimensional finite element models of the resonant bending system with the crankshafts sections with various notch depths are then generated. The resonant frequencies based on the finite element computations are in good agreement with those based on the experimental results. The information on the frequency drop for a given notch depth from the results in this investigation can be used as a guidance to infer the extent of fatigue crack depths in the resonant bending fatigue tests of crankshaft sections. `` 62 Solid Mechanics and materials Hybrid Trefftz Formulation in Finite Element Method and Its Application on Plane Elasticity YeonSeok Choo and Professor Byungchai Lee Chooyeonseok@kaist.ac.kr Keywords: Finite element method, Trefftz, plane elasticity, drilling degrees of freedom Many researchers have tried to get rid of shear locking and improve the performance of plane elements in various ways including reduced or selective reduced integration techniques, assumed strain methods, hybrid or mixed methods, nonconforming mode techniques, and so forth. Jirousek developed hybrid Trefftz variational formulation based on the Trefftz’s variational method and conventional finite element method. Element stiffness matrices were made up by approximating the internal displacement field that satisfys governing equations of plane elasticity problems in the domain of elements and the boundary displacement field generally used in the finite element discretization independently. Allman et al approximated the displacement field by quadratic functions in the element domain to add drilling degrees of freedom to the linear triangular and quadrilateral elements and then, they could improve the performance of the elements. And elements that have drilling degrees of freedom also have an advantage of modeling because the shell elements utilizing them as membrane parts have six degrees of freedom per a node in 3-dimensional space. We introduce efficient and accurate plane elements with drilling degrees of freedom based on the hybrid Trefftz method. By variational formulation, hybrid Trefftz method connects two independent displacement fields: the internal displacement field satisfying governing equations of plane elasticity problems and the boundary displacement field consistent at the inter-element boundaries. In this study, we derive element stiffness of triangular and quadrilateral elements using hybrid Trefftz variational formulation which is based on the total potential energy principle and boundary integrations for stiffness matrices. At the same time, we approximate the boundary displacement field by Allman type displacement field for drilling degrees of freedom. However, we can easily apply it to arbitrary polygon elements because all the domain integrals are changed into boundary integrals. With these plane elements, we performed a series of tests and got good results in view of accuracy, convergence and robustness. `` 63 Solid Mechanics and Materials Microstructures and Failure Mechanisms of Spot Friction Welds in Lap-Shear Specimens of Aluminum 6111-T4 Sheets P.-C. Lin, S.-H. Lin, and J. Pan paicl@engin.umich.edu Keywords: Spot friction welds, aluminum 6111-T4, microstructure, failure mechanisms. Microstructures and failure mechanisms of spot friction welds in aluminum 6111-T4 lapshear specimens are investigated based on experimental observations. Two types of tools, a Type I tool with a flat tool shoulder and a Type II tool with a concave tool shoulder, were used to join the aluminum sheets with different processing parameters. Optical micrographs of the cross sections of spot friction welds made by the two types of tools in lap-shear specimens before and after failure are examined. These spot friction welds show the failure mode of nugget pullout under lap-shear loading conditions. However, the micrographs show different microstructures and failure mechanisms for spot friction welds made by the two types of tools with different processing parameters. The experimental observations suggest that under lap-shear loading conditions, the failure is initiated near the stir zone in the middle part of the nugget and the failure propagates along the circumference of the nugget to final fracture. A schematic illustration of spot friction welding (SFW) process. `` 64 Solid Mechanics and Materials Preliminary Studies on Buckling and Crashworthiness Design with Multidisciplinary Objectives and Uncertainties in the System Chang Qi and Z.-D. Ma, N. Kikuchi, C. Pierre cqi@ umich.edu Keywords: Buckling, Uncertainties Crashworthiness, Multidisciplinary Design Optimization, In this presentation, we will consider fundamental principles of buckling and crashworthiness design, especially with other design objectives (such as durability and NVH) and uncertainties in mind. Uncertainties can be classified into three categories: parameter uncertainties, modeling uncertainties, and uncertainties in the loading and boundary conditions. Uncertainties will have great effects on the results obtained from a deterministic buckling or crash analysis, and it may change the nature and fundamental phenomena of the prediction. We will discuss this through examples. Another issue to be discussed is the relationship between buckling and crashing. Buckling modes have been used to design a structure for crashworthiness, but crashing is not equal to buckling. Structure may fail under the load far below the critical buckling load. We will also discuss this through examples. In the study of vehicle crashworthiness, design of a structure against buckling failure is an important issue. Desired critical buckling loads and buckling modes can be achieved through design optimization including size, shape and topology; this will be the objective of this research. Besides the stability target, durability and NVH targets can also be included resulting in a multidisciplinary design optimization problem. Currently, design against buckling (DAB) of a general purpose mounting system has been studied to investigate the essences of the physical problem, considering the uncertainties mentioned above. The general purpose mounting system can represent an engine mounting system or a cabin-frame mounting system, etc. Multidisciplinary design optimization of a real engineering application in an innovative hydraulic-hybrid vehicle is used as an example to demonstrate the design targets mentioned above. `` 65 Biomechanics Dynamic Modeling of Karate Front Kick Jiro Doke, Professor Arthur D. Kuo jdokeh@umich.edu Keywords: karate kick, biomechanics, dynamic modeling A front kick is one of the most common forms of kick in karate. From observation, the hip and knee joint of the kicking leg go through a sequence of flexion and extension phase. Previous experimental studies showed that, kinematically, the kick starts with hip and knee flexion, then the knee starts to extend, and the hip extends slightly at impact. However, it is not well known how this coordination of joints relates to the performance of the kick, and whether this is the optimal sequence. A rigid two-segment model was created to simulate a closed stance front kick. Torque actuators at the hip and the knee obeyed a force-velocity relationship. These actuators were activated with a constant level of activation during the flexion and extension phase. We varied the levels of activation to examine the relative effect of each phase. For any particular set of activation levels, we systematically simulated for various combinations of two switch timings. The first timing was the time from the beginning of the kick to when the knee torque switched from flexion to extension. The second timing was the time from the first timing to when the hip torque switched from flexion to extension. The simulation terminated when the knee angle reached the final configuration. For each simulation, we noted whether the kick had terminated in the target area, which was a range of about 10 cm around the hip height level. The horizontal foot velocity at kick completion was used as the performance measure. For some sets of knee activation levels, we found an optimal combination of the two switch timings that resulted in the largest final horizontal foot velocity. It is interesting to note that it is possible to perform a kick with only activating the hip torques and no knee activation. The dynamic coupling of the segments allows the lower leg to move in the desired trajectory. Adding some activation on the knee extension phase tends to increase the foot velocity. The highest final foot velocity is achieved at a relatively low knee flexion activation and high knee extension activation. A qualitative look at one of the optimal kicks revealed that hip extension just before the end of the kick increased the horizontal velocity of the foot. Such behavior can be observed in a real kick, in which the deceleration of the thigh segment induces an acceleration of the shank segment. The extension of the hip allowed the foot to be thrusted forward. As the knee straightens, the foot velocity decreases, which suggests that foot impact should occur before the knee is fully extended, ideally when the velocity is at its local maximum. `` 66 Bio-engineering A Comparison of the Forward Fall Arrest in Healthy Young Men and Women Lisa C. Case, Jia-Hsuan Lo, and James A. Ashton-Miller lcase@umich.edu INTRODUCTION: Falls and fall-related injuries will cost the United States $85 billion by the year 2020 (Englander et al., 1996). Sixty percent of falls in older adults are in the forward direction (O’Neill et al., 1994) and 96% of distal forearm fractures occur as the individual attempts to arrest the fall with the upper extremities (Keegan et al., 2004). While there have been studies on the mechanics of forward fall arrests in males (DeGoede et al., 2002), there are no published studies describing the mechanics of forward fall arrests in females. Older women have higher rates (1.2 to 2.2) of falls than older men (Luukinen et al., 1994) and they are twice (1.8 to 2.2 times) as likely to sustain an injury as men (Malmivaara et al., 1993). One factor that may contribute to these statistics is the finding that women have almost 50% less upper body muscle strength per unit body size than age-matched men (Metter et al., 1997). METHODS: A preliminary study of 10 young healthy women was therefore conducted. It was based on an earlier study in young men in the Biomechanics Research Lab at the University of Michigan (DeGoede, 2002; Lo et al., 2003) in order to determine whether gender affects how falls are normally arrested. The women were initially supported in a standardized forward leaning posture with the shoulders either 70, 80 or 90 cm from the ground. The subjects were then released and asked to arrest the forward fall by landing with each hand on a force plate. Impact forces and body kinematics were recorded during each fall arrest. RESULTS: The impact force, normalized by body weight, was similar for both males and females for a given fall height. However, the women adopted a different fall arrest strategy than the men. While the initial elbow flexion angle at impact was similar for both males and females, the change in elbow angle post impact was significantly smaller in the women (~25% of the male average, P<0.05). DISCUSSION: The smaller change in elbow angle in the women during the post-impact “ride down” phase of the fall arrest may be attributed to their smaller upper extremity extension strength compared to men (after normalization for body size). They adopted a strategy that involved maintaining straighter elbows during the “ride-down” phase of the fall arrest, apparently to prevent their elbows from buckling under the impact force and their head or torso striking the ground. Lack of confidence in being able to arrest the fall without injury might also accentuate this. Current exercise interventions tend to focus on maintaining lower extremity strength, but there is less emphasis on upper body strength, especially in women. Our results suggest that elderly women should try to maintain as much upper body strength as possible. `` 67 Biomechanics The Effect of Aging on the Muscle and Neural Control Delay in One-Legged Balance Jaebum Son and Dr. James Ashton-Miller jaebum@engin.umich.edu Keywords: biomechanics, muscle, control delay Falls are one of the most common problems of older people which may cost mobility and mortality, and it is believed that these happen because of the lack of balance ability in the aging. However, no clear answer to this has been provided to understand the mechanism of human balance yet. On the other hand, it was found clinically that one-legged balance time has strong relationship with balance ability or falls, and researchers used this to predict for the possible future falls. In this study, we show what could be significant factors causing a larger balance sway during one-legged balance using control theory. It was hypothesized that the velocity feedback compensates the neural delay and CNS processing time effectively, and Fast Fourier transformation (FFT) and power spectral density (PSD) are used to prove the existence of velocity feedback. The muscle bandwidth was identified in the frequency domain as well. After that, the least square optimization is used to simultaneously estimate the magnitude of the velocity feedback and the delay. 10 young and 10 healthy old subjects volunteered for the experiment and signed the consent form. Subjects stood on the force plates with their arms crossed, and at the signal of examiner, they started one-legged balance up to 30 seconds maximum. Two AMTI® force plates were used to measure the ground reaction force and OPTOTRAK was used for the kinematic analysis. The displacement of the center of mass in frontal plane was calculated with 4 segment model. It was shown that the velocity feedback compensates the neural delay effectively. The older group appeared to have a narrower muscular bandwidth. However, the older group didn’t show a significant longer delay time over the young group. Rather, the sway magnitude defined by the standard deviation of the normalized center of pressure appeared to be significantly correlated with the amount of velocity feedback. Previous studies have failed to prove the existence of velocity feedback in the system dynamic analysis nor could they satisfactorily include the effect of neural delay in the balance model, even though the biological experiments showed significant neural delay and CNS processing time. This research explained the nature of human body sway and provided a novel way to decouple the velocity feedback and neural/CNS delay that match all previous neurophysiological results. `` 68 Bio-engineering Mathematical Modeling to Predict RV Function During Artificial Lung Attachment Jeongho Kim, MS; Hitoshi Sato, MD; Ronald Hirschl, MD;Robert Bartlett , MD ; Keith Cook, PhD jeonghok@umich.edu Thoracic artificial lungs (TALs) can, under certain conditions, lead to elevated right ventricular (RV) afterload, dysfunction, and diminished cardiac output. The objective of this research is to predict cardiac index (CI) during in-vivo TAL attachment with elevated RV afterload using baseline, pre-attachment data. An MC3 BiolungTM, with integral compliance chamber, was implanted in healthy sheep and sheep with pulmonary hypertension. Results indicate that the change in ePSR (ΔePSR) is an effective index to predict the percentage of the change in CI (%ΔCI) using the formula; %ΔCI = 0.00156 ΔePSR 2 - 0.0612 ΔePSR (R2 = 0.78). The ePSR depends on TAL resistance, natural lung resistance, and anastomosis resistance, which vary with flow rate. To calculate ePSR and CI using the baseline data, mathematical models must consider these resistances. The TAL resistance is determined through in vitro experiment. The pressure drop across the TAL was recorded under steady and pulsatile flow conditions, and is a function of flow rate, heart rate and blood viscosity. Natural lung resistance can be measured as a function of flow rate and baseline resistance, which clinically can be determined pre-operatively, but care must be taken during TAL use to avoid changes in natural lung resistance due to inflammation. Anastomosis resistance also can be determined by 1''×1/2''×1'' and 1''×5/8''×1'' T-connectors. Anastomoses resemble T junctions and thus develop fluid mechanical, so-called “minor” energy losses due to a change of direction in the fluid flow. Both 2.0 and 3.0 cP glycerol solutions were pumped through the TAL. Energy loss per unit volume across some components differs from the measured pressure drop due to Bernoulli effects. In some cases results are presented in terms of mechanical energy loss, in other cases it is more convenient to leave results as measured pressure drops. In vitro experiments showed that the pressure drop at the TAL inlet anastomosis was the most significant anastomotic pressure loss. All anastomotic pressure drops to and from TAL and pulmonary artery are modeled as a function of pulmonary artery and TAL inlet graft diameter, cardiac output, blood viscosity, and heart rate. `` 69 Biomechanics Mechanical Response Of The Extracellular Layers of Sea Urchin Eggs Taeyong Kim, Chia-Wei Wang, Leslie Lamberson, and Professor Ann Marie Sastry taeyongk@umich.edu Keywords: jelly coat, sea urchin, echinoid, inverse finite element method, fluid solid interaction The transparent, extracellular layers surrounding the eggs of the sea urchin Arbacia Punctulata account for approximately 3-11% of maternal energy in egg production, and thus likely play an important role in successful fertilization of this free-spawning organism. A shear flow experiment was used to simultaneously deform the egg and jelly layer by causing shear stresses the eggs. The peeling away of egg jelly was observed at the lowest flow rate (3.42 x10-6m3/sec) during the experiment. Egg rupture was also observed at higher flow rate (7.42 x10-6m3/sec) during the experiment. The egg and jelly layer exhibited nonlinear behavior under external loads. The simplest hyperelastic model, the Neo-hookean model, was adopted to model their behaviors. Material properties of the egg and jelly coat were found using an inverse finite element method (IFEM) approach involving a fluid-solid interaction scheme.Shear flow produced stresses on the surface of the egg or jelly layer which satisfied the universal deformation condition due to traction, under assumptions of an isotropic, homogeneous material. The shear modulus of the egg was in the range of 110-160 Pa. However, the shear modulus of the jelly layer varied among the eggs. Some jelly coats had a shear modulus close to that of the egg, while some had 48 – 64 Pa. These differences may be due to interactions between the jelly coat and seawater, decreasing the jelly coat strength over time. Future work will be focused on the relative importance of the jelly coat’s protective role, and its other possible functions in sperm attraction. `` 70 Bio-Engineering Structural Modeling of DNA Loops in Lac-Repressor S. Goyal and N. C. Perkins sgoyal@umich.edu and ncp@umich.edu Experimental studies of DNA have established that its long-length scale structural mechanics play a crucial role in its biological functions including gene expression. For instance, long-length scale supercoiling regulates the unwinding of the smaller-length scale helical coils of its constituent strands (the two sugar-phosphate chains) that enclose the genetic information (the base pairs). Many proteins interact with DNA to deform it into loops (and supercoils) as crucial steps in initiating or repressing gene expression. The goal of our research is to model DNA as a nonlinear elastic rod under bending and torsion to explain its long-length scale looping behavior. Loop formation in elastic rods is often initiated by instabilities under compression and/ or torsion and accompanies nonlinear transitions to more energetically favorable equilibria. These large nonlinear deformations are governed by various structural properties of the rod including its bending and torsional stiffnesses, anisotropy and stress-free curvature. Furthermore, these properties are known to vary along the length of DNA because they depend on the basepair sequence. The dynamics of a DNA strand is also influenced by its physical interactions with the surrounding fluid medium. For example, the fluid exerts hydrodynamic and thermal forces on DNA, and its ionic composition screens electrostatic repulsion of the negatively charged phosphate backbone of DNA. Our dynamic rod model yields a set of nonlinear partial differential equations in time and and space (along the rod’s contour length). These equations need to be solved numerically under known initial and boundary conditions. We employ this computational rod model to simulate various examples of DNA supercoiling, one of which is will be presented herein. The activity of a lactose (sugar) producing gene in the bacterium E.coli is structurally controlled by a “Lac-repressor” protein. The repressor protein binds to two sites (operator regions) on this gene to mechanically deform it into a loop. The crystal structure of this DNA protein complex unfortunately cannot reveal the loop geometry, but it does provide clues about the boundary conditions for the loop. We use our computational rod model of DNA with these boundary conditions to predict the possible loop geometries. Many ongoing experiments on the Lac-repressor protein are exploring the sequence-dependent behavior of looping by working with the various man-made mutants of the gene. To complement these experiments, we will explore through simulation the sensitivity of the loop shape to sequence dependent stiffness, stress-free curvature, and chirality. `` 71 Biomechanics Homozygosity for a Dominant Mutation in col1a1 Restores Bone Phenotype in Comparison to Moderately Severe Type IV Osteogenesis Imperfecta Present in Heterozygous Brtl Mice K.M. Kozloff, C. Bergwitz, T.E. Uveges, T. Chen, M.D. Morris, G. Gronowicz, F. Ledgard, J.C. Marini, S.A. Goldstein kenkoz@umich.edu Keywords: Bone mechanics, osteogenesis imperfecta, genetic mutation The Brtl mouse is a dominant-negative model for type IV osteogenesis imperfecta (OI). Brtl is heterozygous for a glycine substitution (G349C) in one col1a1 allele. Brtl pups have 30% perinatal lethality; surviving Brtl mice have reduced BFR and MAR and smaller, weaker, and more brittle bones than WT. Unexpectedly, mice homozygous for the G349C mutation are not lethal but have viability and size indistinguishable from WT. Only mutant 1(I) mRNA is detected and virtually all 1(I) chains form homodimers. This study characterizes the 1st mouse in which homozygosity for a dominant mutation (Brtl/Brtl) attenuates the phenotype of the heterozygous mouse. Femurs from 2 month Brtl, Brtl/Brtl, and WT mice were assessed for areal BMD by PIXImus, geometry and vBMD by µCT, load to failure in 4-pt bending, and histomorphometry. Tibial sections were imaged by Raman spectroscopy to measure collagen cross linking. Areal and vBMD are normal in the Brtl/Brtl. Femoral cross sectional area is intermediate between Brtl and WT. While Brtl femurs fail earlier in bending than WT, Brtl/Brtl femurs appear normal. Furthermore, Brtl/Brtl femurs do not demonstrate the reduced post-yield displacement characteristic of the Brtl mouse. Ultrastructural parameters suggest Brtl/Brtl appears to rescue hypermineralization and abnormal collagen cross linking in the Brtl matrix. On static histomorphometry, Brtl/Brtl TbN is equal to WT, and significantly higher than in Brtl. TbTh of Brtl/Brtl is intermediate between Brtl and WT, as is BV/TV. Percent ObS and OcS, MAR and BFR/BS were the same in all genotypes. Dermal fibril diameter was significantly larger in Brtl/Brtl than Brtl or WT. In Brtl, approximately 25% of 1(I) chains are linked as a homodimer by S-S bonds between mutant Cys 349 residues. The homodimers form efficiently in collagen heterotrimers and are well-secreted from the cells. Collagen triple helices containing a single mutant chain comprise 50% of the intracellular collagen of Brtl; these helices are not well secreted (30-50%) from cells but do occur in media and matrix. The moderately severe bone phenotype in Brtl may result from a combination of collagen matrix insufficiency and the dominant negative effect of the reactive cysteine moiety. Surprisingly, bone composed entirely of type I collagen containing an S-S dimer appears to be sufficient for supporting normal functional requirements. `` 72 Biomechanics Thrombospondin-3 Effects on Bone Structure and Function J.A. Meganck, S. Hormuzdi, P.B. Bornstein, S.A. Goldstein, K.D. Hankenson meganckj@umich.edu Keywords: Bone mechanics, Matrix proteins, genetic mutation Thrombospondin-3 (TSP3) is a pentameric extracellular matrix protein present in bone tissue. It is homologous to the well characterized cartilage oligomeric matrix protein (COMP, also known as TSP5), however, the role of TSP3 in the skeleton has not been previously examined. Therefore, the goal of this study was to determine the effect of TSP3 on bone structure and function. Mice with a targeted disruption of the TSP3 gene were created to examine its functional significance. The mice were viable and fertile, and embryos developed normally. To examine the effect of TSP3 disruption on post-natal bone modeling, femurs were obtained from male and female TSP3-null and wild-type (WT) mice at 9, 15, and 26 weeks of age. Body weight was measured before harvesting. To determine if an absence of TSP3 protein affected bone geometry, femora were scanned using a micro-computed tomography (CT) system. Bone length, the moment of inertia, cortical thickness, endosteal and periosteal radii and cross-sectional area were calculated on the resulting CT images. Hematoxylin and eosin, Von Kossa and Toludine Blue stains were used to assess histological differences. Four-point bending was used to investigate differences in mechanical properties by measuring the stiffness, yield load, ultimate load, failure load, yield displacement, ultimate displacement, failure displacement, pre-yield energy, postyield energy and total energy. In addition, these mechanical test results were used in conjunction with the CT results to calculate the predicted yield stress and predicted Young’s modulus. Results were considered to be significant if p<0.05 using the MannWhitney U test. Female 9-w TSP3-null mice showed an increase in weight, the moment of inertia, endosteal and periosteal radii, cross-sectional area, yield load, ultimate load, failure load, and a decrease in modulus. Similarly, 15-w TSP3-null females had increased moment of inertia, periosteal radius, cross-sectional area, stiffness, ultimate load, failure load, and post-yield and total energy. Higher values for weight, moment of inertia, endosteal and periosteal radii, stiffness, ultimate load and failure load were also seen in 9-w TSP3-null male mice. When evaluating CT scans, we noted that the femoral head in TSP3-null seemed to develop earlier than in wild-type mice. In TSP3-null mice growth seemed to be completed by 15-w, whereas in WT mice growth had not begun until 26-w. Histological analysis showed that the WT femoral head was composed of hypertrophy chondrocytes in a calcified matrix until 26-w, while TSP3-null femoral heads showed vascular invasion and ossification beginning at 9-w. Overall, these results show that adolescent male and female TSP3-null mice have greater femoral bone volume and strength and accelerated endochondral ossification of the femoral head. `` 73 Biomaterials Keto-reactive coatings for patterning of biomolecules Himabindu Nandivada and Joerg Lahann nhima@umich.edu, lahann@umich.edu Keywords: microcontact printing, surface engineering Patterned polymer films are used as scaffolds for tissue engineering, components in molecular electronic and optical devices, biosensors and in fundamental studies of cell biology. These thin-film coatings provide free reactive functional groups, presenting an attractive option for surface engineering. Chemical vapor deposition (CVD) polymerization has been used to prepare functionalized coatings, for patterning of proteins. The immobilization chemistries for this type of patterning typically involve amide formation. The intrinsic chemical reactivity of the functional groups promotes reaction with biological ligands and can be used for pattern formation using microcontact printing (µCP). However, there is a need for alternative reactive coatings that are compatible with immobilization chemistries other than amide formation. In this study, an approach towards the creation of engineered microenvironments based on coatings with a new reactive polymer coating, poly(p-xylylene pentafluoroethyl ketone) (PPX-CO-C2F5), is reported. The precursor for CVD polymerization, pentafluoroethyl ketone [2.2]paracyclophane, was synthesized via Friedel-Crafts acylation between pentafluoropropanoic anhydride and Fig 1: Fluorescence image of [2.2]paracyclophane in the presence of AlCl3. The TRITC-labeled streptavidin polymer was then synthesized utilizing CVD conjugated to biotin-based polymerization. These reactive polymer coatings ligands, which were patterned present keto groups on their surfaces, which can be onto the reactive coating using then covalently bound to biological ligands with µCP. hydrazide groups. To prove this concept, we used µCP by covalently binding biotinbased ligands to the surface and then using rhodamine-labeled streptavidin to detect them. As shown in Fig. 1, the binding between biotin and streptavidin facilitates the creation of patterns of streptavidin on the polymer surface. The use of streptavidin as a bio-linker generates a platform for further attachment of various biotin-conjugated biomolecules such as proteins, antibodies, polynucleotides or polysaccharides. This research demonstrates a substrate-independent technique for reactive coatings consisting of vapor deposition of a keto-reactive coating and µCP, which can be used for the creation of spatially designed microenvironments. These surfaces can effectively support self-assembly of proteins, antibodies and mammalian cells and thus can be applied in various fields, such as microfluidics and drug delivery. `` 74 Biomaterials Spatial Control of Protein within Biomimetically Nucleated Mineral L. N. Luong, R. J. Patel, and D. H. Kohn lluong@umich.edu Keywords: biomimetic, coprecipitation, mineralization, and protein Coprecipitation is a method used to incorporate protein into an osteoconductive bone-like mineral layer onto an organic substrate, which can lead to an effective growth factor delivery system. A bone-like mineral layer nucleated onto an organic substrate enhances osteoconductivity and mechanical properties 1. Incorporation of protein may also render the mineral osteoinductive. In this study, coprecipitation was used to incorporate bovine serum albumin (BSA) into mineral nucleated onto polylactic-co-glycolic acid (PLGA) films in order to control protein localization. Incorporation was characterized by determining its presence on the film, the quantity incorporated, and its localization. Films were prepared using 5% wt. PLGA/chloroform solution cast in 10 cm Petri dishes. After air drying, films were cut into 4 cm2 squares and etched in 0.5M NaOH for 7 minutes per side. A modified simulated body fluid (mSBF) was used in order to induce mineralization 2. The following groups were examined: (1) 3 days in mSBF, 3 days adsorption, (2) 3 days in mSBF, 3 days coprecipitation, (3) 3 days in mSBF, 2 days adsorption, 1 day in mSBF, (4) 3 days in mSBF, 2 days coprecipitation, 1 day in mSBF and a control group mineralized in mSBF for 6 days. Films were incubated in 40 ml of mSBF with 200 μg/ml of BSA at 37ºC and mSBF was changed daily. For the adsorption samples, 0.25 ml of 200 μg/ml of BSA in PBS was pipetted onto each film. Fourier transform infrared spectroscopy (FTIR) was used to determine the presence of BSA within the mineral layer. BSA quantification was done using a bicinchoninic acid assay and absorbance was measured at 562 nm. Samples were demineralized in 0.01M HCl and agitated at 300 rpm for 3 days. BSA localization was determined by coprecipitating fluorescently-labeled BSA (5:1 ratio of BSA to labeled-BSA) onto the films and examining the films with a confocal microscope. FTIR confirmed the presence of BSA in the mineral. Coprecipitation increased the quantity of BSA in the mineral in addition to controlling the localization of BSA through the mineral. This suggests that BSA is incorporated into the mineral as opposed to weakly adsorbing to the surface. Permutations of growth factors can therefore be incorporated into the bone-like mineral layer and/or the actual polymer by controlling the number of days a growth factor is being coprecipitated. By being able to control the loading and localization of the protein through the mineral thickness, an effective release profile can be achieved. 1. 2. `` Murphy WL: J Biomed Mater Res 2000; 50(1):50 Murphy WL: J Am Chem Soc 2002; 124:1910 75 Solid Mechanics and Materials Ultrasonic Transmission Characteristics of Continuous Casting Slab for Medium Carbon Steel Jun Youn Lee and Professor Soon-Bok Lee leewnsdus@kaist.ac.kr Keywords: ultrasonic, longitudinal wave, Rayleigh wave, continuous casting slab, attenuation coefficient Until now, works to remove surface defects of continuous casting slab have been achieved by forced surface scarfing in order to guarantee intermediate-materials for producing high quality steel materials in industry. In addition, investigations detecting internal defects inside slab have been progressed to improve the quality of continuous casting slab. Now a new effective evaluation technique on surface and internal defects of slab is required for increasing actual incoming rate of slab and acquiring defect-map. It has been reported that the attenuation of ultrasonic wave is very severe in casting structures because of many voids, grain boundaries of coarse grains, surface defects and so on. However, considering the poor surface state and high temperature of continuous casting slab, non-destructive evaluation technique based on stress waves whose transmission is comparatively excellent has to be adopted. Accordingly, this research was performed for getting basic transmission characteristics of ultrasonic wave on continuous casting slab as a preliminary step of advanced ultrasonic defect testing. Ultrasonic wave is classified mainly to three kinds of type, such as longitudinal wave, transverse wave and Rayleigh wave. These three kinds of ultrasonic were applied to carry out experiments to investigate ultrasonic transmission characteristics of continuous casting slab in this research. First, transmission testing of transverse wave was not easy because its initial input energy was not sufficient to travel through thick continuous casting steel and the degree of its attenuation was as well too severe in casting structure. Next, longitudinal wave testing was performed in the frequency range of 0.5MHz to 25MHz and basic data set included attenuation coefficients, its frequency characteristics and so on was acquired. Finally, transmission testing of Rayleigh wave was carried out in the frequency range of 1MHz to 5MHz. From this measurement testing, the basic data set of attenuation coefficients could have been obtained. And Rayleigh waves were also applied on several types and levels of surface defects. The types of surface defect to have been applied in measurement testing are vertical line defects, horizontal line defects, circular defects and closed defects. When Rayleigh wave propagating along the path meets a defect, the energy loss occurs by reflection and dispersion of wave. Consequently the degree of loss on each type of defects was measured by Rayleigh wave testing. `` 76 Material Effects of Impact Velocity on Crush Strength of Aluminum Honeycombs Sung-tae Hong and Jwo Pan sthong@engin.umich.edu Keywords: Aluminum honeycombs, Dynamic crush behavior, Inclined loads Effects of impact velocity on the crush strength of aluminum 5052-H38 honeycomb specimens are investigated by experiments. An impact test machine using pressurized nitrogen was designed to perform dynamic crush tests. A test fixture was designed such that inclined loads can be applied to honeycomb specimens in dynamic crush tests. The results of dynamic crush tests indicate that the effects of impact velocity on the normal and inclined crush strengths are significant. The trends of the inclined crush strengths for specimens with different in-plane orientation angles as functions of impact velocity are very similar to that of the normal crush strength. Experimental results show similar progressive folding mechanisms for honeycomb specimens under pure compressive and inclined loads. Under inclined loads, the inclined stacking patterns were observed. The inclined stacking patterns are due to the asymmetric locations of horizontal plastic hinge lines. These experimental observations provide a better understanding of the dynamic crush behaviors of aluminum honeycombs under pure compressive and inclined loading conditions. u u v One fold H H+D H One fold H-D Plastic hinges (a) Plastic hinges (b) Figure 2 Simple two-dimensional schematics of the stacking patterns: (a) under pure compressive loads and (b) under compression dominant inclined loads. `` 77 Solid Mechanics and Materials High Speed Tensile Test for the Material Properties at the Intermediate Strain Rate Ji-Ho Lim, Seok-Bong Kim, and Professor Hoon Huh ksb79@kaist.ac.kr Keywords: Intermediate Strain Rate, Dynamic Material Properties, Load Ringing Phenomenon The dynamic behavior of a material must be examined to ensure the impact characteristics of an auto-body in finite element analysis. An appropriate experimental method needs yet to be developed to acquire the material properties at the intermediate strain rate ranged from 1/sec to 500/sec. In this study, tensile tests of various different steel sheets for an auto-body were performed to obtain the dynamic material properties with respect to the strain rate which is ranged from 0.003/sec to 200/sec. For tensile test at intermediate strain rate, a high speed material testing machine (HSMTM) of servo-hydraulic type was developed. This apparatus has the maximum velocity of 10 m/sec to obtain the dynamic material properties at the strain rate of up to 500/sec. And a special jig fixture of a load cell was designed to reduce the trembling of the load signal. This load-ringing phenomenon is induced by unstable stress propagation along the specimen at the high strain rate. In case of high speed tensile test, there is no special regulation about shape and size of the specimens. Therefore it is necessary to decide adequate type of specimen for tensile test at intermediate strain rates. In this study, dynamic tensile specimens were decided by finite element analysis considering several shape factors, length(L), width(W) of gauge part and radius(R) of fillet part. The shape L=20mm, W=6mm, R=6mm(L20W6R6) were used at range of 0.1~100/sec and L15W6R6 were used at 200/sec strain rate. From the dynamic tensile test, stress-strain curves were obtained for steel sheet SPCC, SGACD, SPRC35R and SPRC40R with the variable strain rates. And the sensitivity of yield stress for each steel sheet was observed according to the strain rates. The fracture elongation for each sheel sheet is decreased at the strain rate of static to 0.1~0.5/sec, then it is increased to 10~20/sec and decreased again at more high strain rates, like an `S` shape. These stress-strain curves, relationship of the yield stress and the elongation to the strain rate are significant not only in the crashworthiness evaluation under car crash but also in the high speed metal forming. `` 78 Solid Mechanics and Materials Determining material properties of thin films on substrates Kristen L. Mills and Professor Michael Thouless klmills@engin.umich.edu Keywords: thin films Thin films are often used on components of micro-devices as dielectric coatings and for thermal or diffusion protection. They also occur incidentally on a material in an environment that provokes a surface reaction. Manufacturing technology and processing advances have allowed thin films to be cast, deposited, or grown in layers as thin as a few nanometers. The challenge that this poses for the materials engineer is determining the material properties at these very small length scales. In most cases, direct measurement of the material properties of the film is impossible. Plasma oxidized Polydimethysiloxane (PDMS) will be used to illustrate a methodology for determining the material properties of a film, in this case the plasma-treated layer, for which neither the thickness of the layer nor any of its material properties are known a priori. This thin film is currently providing a platform on which cell biologists are studying the adhesion, migration, and proliferation of cells. PDMS sheet is fabricated and then plasma oxidized to create a very thin oxide layer on the surface of the PDMS. Subsequently, nano-cracks are produced in this layer in the direction perpendicular to an applied strain. The cracks provide a bio-mimetic and reconfigurable pattern in which proteins are placed for the adhesion of cells. Controlling the crack patterns necessitates an understanding of the mechanics of nanocracking. This, in turn, requires knowing the modulus, toughness, thickness, residual strain of this layer and, perhaps, cohesive strength of the layer. The behaviors of the film that may be used to deduce information about it will be discussed as will measurement methods that are required at the scale of hundreds of nanometers to analyze them. `` 79 Soild mechanics and Material Study on interfacial delamination of thin film/substrate structure by push-off test Woo Sung Choi and Youn Young Earmme woosung@kaist.ac.kr Keywords: bridged thin film, delamination, nanoindenter In recent years, thin films and coatings have been increasingly used in various applications, including bio-electronic systems, micro/nano electronic devices, MEMS or NEMS , etc. In order to design and fabricate these devices, it is essential to measure the mechanical properties and interfacial toughness of thin films. The mechanical properties are closely related to device performance and reliability. However, it is difficult to measure the mechanical properties of thin films because of its small feature size. Several techniques have been applied to the mechanical characterization of thin films, such as nanoindentation, micro/nano tensile test, membrane deflection test, and so on. Interfacial delamination is related to lifespan, and structural integrity of thin film adhesion, it was not until the introduction of a fracture mechanics approach that interfacial adhesion strength was studied extensively and systematically. Many adhesion test techniques have been developed to measure the adhesion energy of interface, such as blister test, peel test, pull-off test, etc. In this study, the push-off experiment of bridged gold thin film on silicon substrate using nanoindenter was carried out to measure the mechanical properties of gold film and the critical energy release rate as the interfacial delamination criterion between the gold film and silicon substrate. Analytical constitutive relations are derived here based on membrane theory and are compared with experimental results. The critical energy release rate was evaluated based on the general concepts of interfacial fracture mechanics. In order to compare analytical result with experimental one, two-dimensional geometricallynonlinear FEA (finite element analysis) is also carried out to simulate the push-off experiment, and the energy release rate is calculated. FORC E `` 80 Tissue Regeneration and Cellular Biotechnology Micro-device for manipulating and shaping cells in tissue engineering Konstantinos Varsos and Jonathan Luntz kvarsos@umich.edu Keywords: Cell manipulation, Tissue engineering, Programmable force fields In many biological applications the manipulation of bio-material is very useful. The desired task is to be able to handle bio-particles to bring them to a desired position and orientation. Particle manipulation includes basic functions like particle detection, sampling, analysis, separation, isolation and conveyance. These functions can effectively be used in biological systems in several applications like biochemical reactions, sample analysis and synthesis, molecular genetics, biotechnology production, development and testing, clinical diagnostics, cell manipulation, lab-on-chip, etc. This research focuses on manipulation of cells by creation of force fields using the electrical phenomenon of dielectrophoresis (DEP) for the application of bioengineering of muscle tissue. For this purpose we have constructed a linear array of electrodes which based on the distributed manipulation theory, can bring cells to a certain position with certain orientation. We provide an analysis of the manipulating device. `` 81 Bioelectrics An algorithm for design of power systems for single and multicomponent devices: a case study focusing on a MEMS environmental test monitor Kimberly Cook and Dr. Ann Marie Sastry amsastry@umich.edu Keywords: power supply, battery, MEMS, gas chromatography Fine manipulation of the smallest of analytes using microscale devices for biological assay, separation and catalysis implicitly requires reconsideration of power supply. Power sources typically exceed the mass and volume of all other subsystems of a MEMS device, and thus commensurate reduction in the sizes of power supplies is required to maintain device portability. This is particularly critical in applications wherein the sampling device is designed to be small and easily deployed, such as the University of Michigan WIMSERC environmental monitoring device. This testbed comprises a small sensor capable of detecting dozens of environmental contaminants within a few minutes, using a microscale gas chromatograph sampling a very small volume of ambient air. Our objective is to design an optimal hybrid power supply for this device.Our algorithm allows design of both single and multi-component power systems. Three methods of optimization have been developed for generic MEMS devices: 1) specification of single-source power supply based on aggregate power profiles, 2) determination of optimal (minimum mass and/or volume) hybrid power systems, based on ranges of power required, and 3) identification of optimal hybrid power supplies based on constrained locations within the system. A stepwise outline of the algorithm follows: 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. `` User supplies power targets and environmental constraints. Environmental requirements are used to eliminate electrochemistries. Subdevice performance parameters are computed. Approaches 1, 2, and 3 are applied to subdevice parameters. Energy, voltage, and current ratios (maximum/available from cell) are computed. Conditionality statements are applied. Power configurations are eliminated based on mass, volume, or area target values. Batteries are selected based on specific or energy properties for Approaches 1 and 2, and based on packaging constraints for Approach 3. Batteries are selected based on maximum lifetime. Results from all three approaches are compared and the system is selected, based on initial user criteria, or if multiple strategies are feasible, by longest lifetime. 82 Bioelectrics Nano-tubular structured conducting polymers for neural prostheses applications Mohammad Reza Abidian, Professor David Martin mabidian@umich.edu Keywords: Nanofibers, electrospinning, Nano-tubes, electrochemical polymerization, neural prostheses Conducting polymers, Neural prosthetic devices, and specifically microelectrode arrays, facilitate the functional stimulating or recording of neurons of the Central Nervous System (CNS) and Peripheral Nervous System (PNS). The interface between microfabricated neural microelectrodes and neural tissue plays a significant role in the long term performance of these devices. It is thought that biocompatible polymer coatings can stabilize the interface between microelectrode and living tissue at the site of implantation. The ability of neural electrodes to record high signals over extended periods of time remains the significant problems. The engineering of bioactive electrode coatings has been investigated for its potential to promote in-growth of neural tissue, reduce shear stress, and enhance signal transport from electrons to ions at the electrode-host interface. We have found that films of electrospun nanofibers can be deposited on the surface of these devices, followed by electrochemical polymerization of conducting polymers such as polypyrrole or poly(3,4-ethylenedioxythiophene) in the presence of counterions. After polymerization, nanofibers templates can be dissolved, leaving tiny channels, pores and nano tubular structures in the conducting polymers. This morphology facilitates efficient signal transport and communication with the neural tissue. The electrical properties of the polymer functionalized probes were examined with impedance spectroscopy and cyclic voltametry. The impedance spectroscopy revealed that the impedance of gold electrode significantly decreased from 800 kΩ to 8 kΩ. The surface morphology of the coated electrodes was assessed by optical microscopy and scanning electron microscopy. Scanning electron microscopy showed the nano tubular structure of conducting polymers on the electrode sites. `` 83 Bioimaging Quantitative Contrast Analysis of In Vivo Ultrasound Imaging: A Study With a Combined 3D Ultrasound/Digital Mammography System Rebecca C. Booi, Gerald L. LeCarpentier, Marilyn A. Roubidoux, Ajay Kapur, Ramon Q. Erkamp, and Paul L. Carson rbooi@umich.edu Keywords: medical imaging, breast, sonography A combined 3D ultrasound/digital mammography system is being developed to better detect and/or characterize breast lesions. It was hypothesized that quantitative measurements of image quality would reveal only modest differences in lesion image quality between direct contact hand held scanning and automated scanning through a mammographically-compatible compression paddle using this system. Automated 3D ultrasound/digital mammography (AUS/DX) studies and direct contact, hand held scans were performed on 10 women with simple cysts. The whole breast, AUS was performed through a mammographic plate 1.0mm or 2.5mm thick, with a GE Logiq 9 M12L transducer array at 10 MHz. Gain was adjusted higher than usual so the upper 1/3 of the cyst showed measurable signal.Signal in the cyst to within 1 mm from the wall was compared with that from adjacent fat and glandular tissue. Log decompressed signal was averaged over five slices in the ROI. In automated (and hand) scans, signal levels were: cyst -67.7 (-68.7) dB; fat -51.7 (-52.1) dB; and glandular -45.2 (-43.5) dB. This indicates contrast in automated (hand) US scans were 14.1±9.7 (16.1±8.7) dB between fat tissue and cyst, and 25.2±20.6 (26.8±22.5) dB between cyst and glandular tissue. Mean depths of the centers of the cysts in the two scan modes were 18.5±1.78 (17.6±2.95) mm. With the automated system, relative contrast loss in vivo is apparently from increased reverberation and multiple scattering signal in the essentially echo free cysts and signal attenuation in the plate and in the greater depth of the cysts from the transducer. These contrast losses are approximately consistent with the signal loss (~4 dB) and increased reverberation levels (~1 dB) measured when imaging line targets through the compression paddles. Half the signal loss through the paddles can be compensated with no increased ultrasound exposure levels to the patient by increasing the transmitted power. The small contrast loss is consistent with radiologist impressions that the image quality was modestly reduced compared with expert scanning. The differences may well be worth the advantages of whole breast AUS and can be reduced by employing a transducer of lower frequency. `` 84 Bioimaging Entropic Graphs for Simultaneous Multi-image Registration and Atlas Construction Huzefa Neemuchwala, Alfred Hero, Paul Carson and Charles Meyer hneemuch@umich.edu Keywords: entropic graph, atlas, registration, nearest neighbor, mutual information In many applications, fusion of two or more images acquired via sensors requires image alignment to an identical pose, a process called image registration. Image registration methods select a sequence of transformations to maximize an image similarity measure. Recently, we introduced a new class of entropic-graph similarity measures for image registration [1]. We extended image registration to higher dimensional feature spaces using Renyi's generalized alpha-entropy. The alpha-entropy is estimated directly through continuous quasi additive power weighted graphs such as the minimal spanning tree and k-Nearest Neighbor graph. Estimates of Renyi-mutual information are derived for multidimensional feature distributions using entropic graphs. A significant application of this technology is that it allows us to generate atlas images for image databases. Anatomic atlas images are widely used for registration, automatic segmentation, gene mapping and image retrieval. Image registration can be accomplished by mutual information minimization for an entire set of images that contribute to a multidimensional feature probability density function. Histogram methods for density estimation are largely unsuccessful in constructing atlases due to the exponential growth of computer memory required to build higher dimensional histograms. The use of graph methods allow us to form atlas images for image databases with significant computational ease as opposed to histogram methods. A second application is the registration of multiple images aimed at tracking disease and possibly tumors through registration of several time-sampled images of patients simultaneously. The higher dimensional feature sets used in this work include wavelets and image moments. We propose initially to generate image atlases for the Yale face database [2], but intend to extend our work to 3D medical images of the brain, imaged using magnetic resonance imaging. Multi-image registration will be demonstrated over ultrasound images of the breast from a patient undergoing chemotherapy for breast cancer treatment. 1.Neemuchwala HF and Hero AO, “Entropic graphs for registration”, to appear in Multisensor image fusion and its applications, Eds. R. S. Blum and Z. Liu, Marcel-Dekker, Inc 2004. 2.Georghiades AS, Belhumeur PN and Kriegman DJ, “From Few to Many: Illumination Cone Models for Face Recognition under variable lighting and pose”, IEEE PAMI, vol. 23(6), pp 643-660, 2001 `` 85 Bioimaging Effects of acquisition parameters and reconstruction methods on the correction of motion and susceptibility artifacts in fMRI K. K. Pandey, B. P. Sutton, Lauren Maddox, D. C. Noll kpandey@umich.edu Signal loss due to intravoxel dephasing and off-resonance image distortions are two major manifestations of magnetic susceptibility artifacts in functional MRI. Head motion changes the orientation of tissue interfaces relative to B0 and thus, the appearance of these distortions in raw T2*- weighted images. Incorporation of methods that abate image distortions and intra-voxel dephasing significantly reduced the error between the reference image and movement corrected image. In this study, we examine the effect of acquisition parameters and reconstruction methods on motion correction in fMRI while the imaged phantom is continuously moving across the time series of images. Data was acquired using a spherical, layered susceptibility performing motion routine with maximum angular displacement of ~8 degrees. Images were acquired using a GRE spiral pulse sequence (TE 27 ms, FOV=24 mm), single-shot spiral-in/spiral-out acquisition and reconstructed using a conjugate phase image reconstruction. Spiralin/spiral-out images were reconstructed using an iterative method using dynamically updated fieldmaps. Images were motion corrected using FSL, and the realigned images were subtracted form the reference image. The error calculated was compared across the various acquisition parameters and reconstruction methods to determine which parameters and reconstruction methods would lead to the most accurate and complete motion corrected images. On average, the spiral-in /spiral-out images reconstructed with the iterative reconstruction method using dynamically updated field-map were most accurate, followed by the spiralin, spiral-in/spiral-out images, and the spiral-out images being the least accurate. A comparison of the pre and post motion corrected images also revealed that motion correction was most effective in the images reconstructed with the iterative method (33% error reduction) compared to CP spiral-out (28%) and CP spiral-in/out & spiral-in (~25%) respectively. We found that the use of acquisition parameters that are less sensitive to off-resonance and susceptibility artifacts, along with the incorporation of dynamic estimates of susceptibility-induced inhomogeneities in presence of motion during imaging, results in better motion corrected images. Acquisition methods that are more robust to susceptibility artifacts, namely, spiral-in and spiral in-out acquisitions produced more accurate motion corrected images. As expected, the iterative method using the dynamic field-map estimates resulted in more complete motion correction since these field-maps were able to account for motion induced dynamic changes in the local field inhomogeneity and off resonance effects due to motion. `` 86 Bioimaging Optical and ultrasonic monitoring of laser-generated intracellular contrast agents: initial cell culture studies M.J. Zohdy,C. Tse, J.Y. Ye, L. Balogh, T. Norris, M. O’Donnell Acoustically monitored laser-induced optical breakdown (LIOB) can be used as an important diagnostic and therapeutic tool in living cells. With properly controlled laser parameters, optical breakdown is a minimally invasive means to target a single, transient, acoustically detectable contrast agent (microbubble) within a cell, without affecting its viability. With different laser parameters, optical breakdown can effectively obliterate a target cell. Simultaneous real-time acoustic and optical microscopy can monitor this range of effects. In this study, experiments were performed on a monolayer of CHO-K1 (Chinese hamster ovary) cells cultured on a glass coverslip. To initiate and monitor intracellular photodisruption in real time, we have developed a system integrating an ultrafast laser with optical and acoustic microscopy. A regeneratively amplified Ti:Sapphire laser produced the breakdown, and a highfrequency (50 MHz) ultrasonic transducer, confocal with the laser, monitored the resultant bubble via continuous pulse-echo recordings. The photodisruption was also observed using optical microscopy, and the viability of each target cell was assessed after laser exposure using conventional live/dead staining. By varying laser pulse fluence (from a minimum of 7 J/cm2 to 112 J/cm2) as well as the number of applied pulses, a broad range of intracellular effects was studied. When up to 5000 laser pulses were applied at the minimum fluence, a small (1μm), transient bubble was generated. Target cells in this regime retained viability several hours after laser exposure. In contrast, with even a few laser pulses at high fluence, a large (>6μm) stable bubble was formed, and target cells were consistently killed in this regime. Geometric targeting within cells can thus generate acoustically detectable microbubbles without introducing exogenous agents. Furthermore, by incorporating biochemical targeting agents, this system can also be used as a powerful tool for molecular diagnostics (e.g. detecting targeted molecular agents without affecting cell viability) and therapy (e.g. by destroying targeted cells without damaging cells in the vicinity). `` 87 Dynamics, Systems and Controls DETERMINING MODEL ACCURACY AS A FUNCTION OF INPUTS AND SYSTEM PARAMETERS Bryon Sohns, Prof. Jeffrey L. Stein bsohns@umich.edu Keywords: Model Accuracy, Model Validation Vital to the effectiveness of simulation-based design is having a system model of known quality. Previous research introduced an algorithm called AVASIM for assessing model validity systematically and quantitatively. AVASIM assess the accuracy and validity of a model based on a specific input and set of system parameters. The purpose of this presentation is to present a AVASIM-based methodology that defines a range of validity of a model with respect to input and system parameter variations Two illustrative examples are presented to explore the feasibility of the proposed procedure. The first example analyzes a linearized version of a nonlinear transient vehicle-handling model. This model’s accuracy and validity are evaluated with respect to variation of two system parameters, resulting in a two-dimensional range of validity. Then a complex nonlinear hydrogen fuel cell model is linearized in order to investigate its accuracy and validity with respect to two input parameters. This again results in a two-dimensional range of validity, but with respect to input rather than system parameters. The results agree well with what is expected for the various models based on knowledge of the effects of linearization on model accuracy. The proposed algorithm for assessing model range of validity is a promising tool for determining model quality and thus potentially useful for simulation-based design. `` 88 Dynamics, Systems and Controls Using Neural Network Surrogate Models to Optimize the Valve Timings for a 2.4 Litter VVT Engine Bin Wu, Zoran Filipi and Dennis Assanis bwuz@engin.umich.edu Keywords: spark-ignition engine, variable valve timing, optimization, neural network In the past thirty years, various Variable Value Timing (VVT) technologies were developed to improve fuel economy, to increase torque generation, and to reduce pollutant emissions. All those new technologies provide more flexibility in controlling the breathing behavior of the engine. Accompanied with the extra flexibility, there are more independent actuators that require proper controls. In conventional Spark-Ignition (SI) engines, the two primary independent actuators are the fuel injector and the spark for each cylinder. Independent camphasing doubles the number by introducing the intake and exhaust camphasers. Consequently, we have to define the desired camshaft positions for each engine operating point, i.e. the combination of engine speed and load. In this study, the optimization of camshaft positions is investigated. The optimization objective varies with respect to the engine’s operating mode. At full load, the optimization objective is maximizing the torque generation, and the camshaft positions are regarded as functions of engine speed only. Under part load conditions, the optimization objective is reducing the fuel consumption while satisfying torque command. The optimized camshaft positions are regarded as functions of both engine speed and load. In this study, we propose using Artificial Neural Networks (ANN) as surrogate models for torque generation and brake specific fuel consumption (bsfc) of the 2.4 liter VVT engine. The ANNs learn the desired relationship from training samples. The training samples are collected on a dynamometer test facility for representative combinations of intake and exhaust camshaft positions, engine speed, and intake manifold pressure. Systematic structure sweeps are conducted to find out the best network structure for each ANN model. Then, the optimization is conducted on the ANN surrogate models for selected operating points. Finally, the optimized results are organized as lookup tables that can be implemented into the Engine Control Unit (ECU). The proposed algorithm can be potentially extended to include more degrees of freedom, such as valve lifts and durations, that will emerge with more general Variable Vale Actuation (VVA) technologies. `` 89 Dynamics, Systems and Controls CT-free Cup Orientator Using Sensors In THR Byunghoon Ko, Sukhoon Park, and Yongsan Yoon bhko@kaist.ac.kr Keywords: Image guided surgery, CT-free, Total hip replacement The purpose of this research is to propose CT-free cup orientator using tilt sensors without expensive point tracking devices in total hip replacement. In the case of using a mechanical guide, the accuracy of cup orientation can be sacrificed because of change of the patient’s posture during procedure. Several navigation systems have been introduced to secure an accurate position and orientation of the implant in THR. These systems are expensive and have some weakness due to possible interference in optical measurement. Our orientator employs a T-bar shaped gauge and economic tilt sensors to secure a fairly accurate orientation of acetabular cup in THR. A Study on the Design of an Acoustic Actuator Based on the Singing Mechanism of Cicadas Wan-Ho Cho and Professor Jeong-Guon Ih elen@kaist.ac.kr Keywords: Cicadas, Acoustic actuator This study was motivated by the fact that the cicadas sound is very loud and broad-band whereas its body size is quite small. These facts suggest that the singing mechanism of cicadas can offer a good idea in the design of an acoustic actuator. The main parts of cicadas singing organ are comprised of abdomen cavity and tymbal. This study is interested in tymbal system. Tymbal action was modeled as a nonlinear motion of a curved shell. The results revealed that such an analogous system to the cicadas singing organ can suggest a design concept for a new acoustic actuator. `` 90 Design and Manufacturing Modular Logic Control for Reconfigurable Manufacturing Systems Emanuel Almeida and Dawn Tilbury {almeidae, tilbury}@umich.edu Keywords: Logic Control, Reconfigurable Manufacturing, Finite State Machines Contemporary manufacturing systems are incredibly complex, consisting of hundreds of machines working together in a coordinated fashion to produce parts. The complexity of the machines leads to complexity in their control systems, and complexity is expensive. The controls for a new machining system can often consume half of the systems construction time and cost. A more effective way to program these types of manufacturing controllers could lead to significant economic savings. The Modular Finite State Machine (MFSM) framework is a new way of designing and programming control logic. This framework allows complicated control problems to be broken down into manageable blocks for design purposes. A module can be dedicated to a single mechanical module, or to a single logical function. A designer can then focus on the logic of that module, its interaction with the adjacent modules, and a small portion of the physical system. This framework has been used at U of M to control several test beds and manufacturing systems. The latest implementation has been the design of the System Level Controller (SLC) for the Reconfigurable Factory Test Bed (http://eclipse.engin.umich.edu/RFTindex.html) at the Engineering Research Center. MFSMs are used to provide the SLC with the necessary “intelligence” to control and manage a whole manufacturing system, including both hardware and software components. The hardware components include a Serial Parallel Machining Line (with several CNC machines and robots inside manufacturing cells joined by a conveyor) and an AGV. The software components include a Virtual Factory Manufacturing Cell and Assembly Cell, a Diagnostic Database and HMI Interfaces. This system has a distributed control architecture where most communication is done using OPC, an open standards protocol for communication, making it an extremely modular, scalable and reconfigurable manufacturing control system. `` 91 Design and Manufacturing Closed-Loop Tape Springs as Fully Compliant Mechanisms Preliminary Investigations Christine Vehar, Dr. Sridhar Kota, and Dr. Robert Dennis cvehar@umich.edu, kota@umich.edu, bobden@umich.edu Keywords: compliant mechanism, tape spring mechanism, closed-loop tape springs, compliant joints, bi-stable mechanism The paper introduces tape springs as elements of fully compliant mechanisms. The localized folds of tape springs serve as compact revolute joints, with a very small radius and large range of motion, and the unfolded straight segments serve as links. By exploiting a tape spring’s ability to function as both links and joints, we present a new method of realizing fully compliant mechanisms with further simplification in their construction. Tape springs, typically found in carpenter tape rules, are thin-walled strips having constant thickness, zero longitudinal curvature, and a constant transverse curvature. The paper presents a closed-loop tape spring mechanism. By representing its folds as idealized revolute joints and its variable length links as sliding joints connecting rigid links, we present a modified Gruebler’s equation to determine its kinematic and idle degrees of freedom. To realize practical utility of tape spring mechanisms, we propose a simple actuation scheme incorporating shape memory alloy (SMA) wire actuators and successfully demonstrate its performance with a proof-of-concept prototype. The paper also presents potential applications for actuated tape spring mechanisms including a large displacement translational mechanism, planar positioning mechanisms, bi-stable, multistable, and variable stiffness mechanisms. `` 92 Design and Manufacturing MACHINING OF ELASTOMERS Jie Luo and Albert Shih jluo@umich.edu Keywords: Elastomer machining, Cryogenically cooling, Chip formation, Induction heating Novel methods, elastomer machining using sharp, woodworking tools, the machining of cryogenically cooled elastomers, and the machining with an induction-heated tool, to enable the effective machining of elastomers are presented. Use of some down-cut endmilling tools effectively removed the elastomer material at room temperature and generated a clean groove. Cooling the elastomer workpiece by solid carbon dioxide improved the machined surface finish. Optical pictures and SEM micrographs were used to examine and classify chips. The induction heating is applied to raise the temperature of an end milling tool for machining of elastomers. Experiments are conducted to study the effect of tool rotation and model the heat transfer between the tool and thermal insulator. Some end milling tests with induction heated tool were performed and results showed that the use of heated tool improves the surface appearance of the milled cuts. Development of 3D position tracking System using PSD(Position Sensitive Detector) sensors for surgery Hyunjun Shin, Yougsan Yoon bhlee@novic.kaist.ac.kr Keywords: 3D position measurement, PSD sensor, tracking system, active marker Currently, most of the 3D position measurement devices for surgery use image sensors. They have resolution order practically and they use markers. However, most 2D image sensors (CCD or CMOS) need massive calculation to find marker center. In this research, we are going to use PSD sensor. PSD sensors are suited for position detector sensor in that their output give the coordinate of marker center directly. In this research, we are going to explain how to measure the accurate position of marker. And we are developing this system with primary target of total hip replacement surgery. `` 93 Design and Manufacturing Characterization of Friction Drilling Process: Force, Torque, Temperature, and Material Analysis Scott Miller and Professor Albert Shih scotfran@umich.edu Friction drilling is a nontraditional drilling method developed to penetrate a hole and create a bushing in a single step. The relevant concept of this technique is heat generation from frictional force between a conical tool and a sheet metal workpiece, which softens and allows displacement of workpiece material into a bushing shape. However, details of this concept are not fully understood. This research studied aspects of friction drilling including measurements of force, torque, and temperature during the process. A model of force and torque was developed and compared to experimental results. Optical Methods for Reconfigurable Precision Measurement Zhenhua Huang and Professor Albert Shih, Jun Ni zhenhuah@umich.edu Keywords: Optical measurement This research studies non-contact optical stereovision and laser holography methods for precision reconfigurable measurement of automotive powertrain components and porous foam materials. This study is motivated by the situation in industry that fast, accurate, and full surface sampling optical methods for online powertrain component measurement are on high demand. In this study, the accuracy and gage repeatability and reproducibility (R&R) of the two systems for precision measurement are evaluated. The effect of the commonly-used powder spray on the accuracy and gage R&R of specular surface measurement is quantified. An algorithm is proposed for plane feature extraction of porous foam materials. `` 94 Design and Manufacturing COMPLIANT PART ASSEMBLY MODELING AND DIMENSIONAL VARIATION DIAGNOSIS USING DESIGNATED COMPONENT ANALYSIS Chino Imediegwu Products made of compliant sheet metals are widely used in the automotive, aerospace, and electronics industries. One of the paramount challenges for the assembly process of such compliant parts is the assembly dimensional variation which affect end product functionality, reliability and perceived quality. This is particularly true for compliant, non-rigid parts because clamping and joining operations during assembly may introduce more dimensional variation as a result of deformation and springback phenomena. To this effect, various methods for analyzing or diagnosing sources of dimensional variation have been developed with the aim of enabling quick detection and localization of assembly process faults based on inline dimensional measurements. Furthermore, in seeking to improve engineering product designs and reduce the number of problems that occur during the assembly of a new product due to dimensional variation, manufacturing firms have focused more on integrating downstream product development processes in earlier design stages. This has been made possible by practices such as concurrent engineering, partnership sourcing, design for manufacturability, process driven product design and modular design. The integration of resources and methodologies have typically been effected on the front end of product development in scenarios characterized by complex products with complicated assembly processes such as the automotive industry. In such situations, manufacturing firms have employed sequential validation techniques to approve components, then subassemblies and finally the end product. This sequential process validation approach is typically characterized by increased costs due to rework and lengthened lead times. This study seeks to improve designated component analysis as an analytical tool and then use it to evaluate, quantify and correct dimensional variation in compliant sheet metal assembly particularly for non orthogonal designated patterns. This tool can then be utilized to ensure a significant reduction in product validation time, cost and tool rework through out the assembly process. `` 95 Design and Manufacturing Vehicle Crashworthiness Design via Equivalent Mechanisms and Crash Mode Matching Karim Hamza and Professor Kazuhiro Saitou khamza@engin.umich.edu This research is motivated by the difficulty that faces vehicle designers when tackling the task of crashworthiness design. Vehicle structure behavior during crash is often unpredictable and requires enormous computational resources to simulate. Approximate models are introduced, which draw upon the analogy between the collapse of the vehicle structural members and the motion of space mechanisms. The equivalent mechanism models offer physically sound approximations, which retain the gross behavior or crash modes of real vehicle structures. Preliminary results show success in providing insightful guidance to improving sub-optimal designs at a vastly reduced computational effort compared to direct optimization approaches. Design of heat-reversible snap fits for space frame bodies Mohammed Shalaby and Dr. Kazuhiro Saitou mshalaby@umich.edu Recent legislative efforts to reduce the environmental impacts of the life cycle of manufactured products have increased the need for component reuse and recycling. Although aluminum space-frame is a good solution, its recycling is still a problem. Snapfit is a preferred joining method because: no need of separate fasteners, easily assembled, can be disassembleable, reduces overall product cost and makes the recycling process more economic, and provides clean separation between frame and panel. This research proposes heat actuated reversible snap-fits, for vehicle frame/panel assembly. Optimum location of these snaps, meeting certain NVH requirements, is found using genetic algorithms and ABAQUS. `` 96 Design and Manufacturing A Transport Model Approach for Developing Microfiltration Compatible Metalworking Fluids Fu Zhao, Andres Clarens, and Steven Skerlos fzhao@umich.edu, aclarens@umich.edu, skerlos@umich.edu Keywords: Metalworking fluids, microfiltration, design for environment As a recycling process, microfiltration of semi-synthetic metalworking fluids (MWFs) has been shown to increase the longevity and quality of MWFs, and reduce the environmental and occupational health risks associated with MWF applications. Research is currently being performed to better understand the transport of MWFs through microfiltration membranes, including mechanisms of membrane fouling. A mechanistic model was developed to describe the flux decline during microfiltration, and to correlate experimentally observed flux with transport retardation mechanisms. Parameters involved in MWF design such as oil content, surfactant to oil ratio, and surfactant structure were investigated, and guidelines for formulating microfiltration compatible MWFs were developed. Preference Coordination in Engineering Design Decision-Making Jeremy Michalek, Fred Feinberg, and Panos Papalambros michalek@umich.edu Design optimization methodologies offer assistance to engineers in achieving product performance objectives; however, in practice most design problems involve tradeoffs among a set of competing objectives such as performance, cost, and marketability. It remains an open question: “How can a designer best navigate these tradeoffs to select the most preferred design, particularly when social and economic preferences conflict with user preferences and the user population itself is diverse?” Preference coordination draws upon the rich literatures in marketing, economics, and psychology to model preference structures of individuals and groups and coordinate these preferences with design models of engineering performance. The rigorous coordination of these models assists the designer in making tradeoff decisions by providing usable information about consumer preferences for product characteristics and price, economic preferences of the producer, and societal preferences such as reduced environmental impact. Use of preference coordination is demonstrated to improve profitability substantially relative to disjoint decision-making. When coupled with models of heterogeneous consumer preferences, manufacturing systems, and public policy models, it can be used to design product lines and to study the effects of regulation policy on design decisions for navigating the tradeoff between private and public preferences. `` 97 Design and Manufacturing Design for product-embedded disassembly Shingo Takeuchi and Professor Kazuhiro Saitou stakeuch@umich.edu With growing interest in recovering materials and subassemblies within consumer products at the end of their lives, there has been an increasing interest in Life-cycle design that generally determines their desirable disassembly sequences in which ecointensive, eco-valuable components (subassemblies) are efficiently retrieved. The objective of this study is to determine near optimal configurations of a product with product-embedded joints when a disassembly sequence is given by Life-cycle assessment. Since the search space is quite large even for relatively simple products, genetic algorithm (GA) is utilized to rapidly approximate optimal solutions. `` 98 Fluid Mechanics, Heat Transfer and Combustion Numerical Simulation of Combustion Driven Oscillations in Gas Turbine Hyoun Jun, Kim and Professor Shin kris@kaist.ac.kr This study is motivated by the need to reduce combustion noise of gas turbine systems. In order to understand cause of the combustion noise, computational method is introduced. Its purpose is to explore qualitatively fundamentals by calculating another models .This study will show the preliminary results through the verification of numerical code and then investigation of the pressure fluctuation behavior on the dump combustor. Our ultimate goal is to understand and develop control strategies for combustion noise by expecting effects of pressure oscillation. Flow and heat transfer analysis for the performance improvement of Cross-flow fin-tube heat exchangers Cheensu An and Professor Dohyung Choi ancheensu@kaist.ac.kr The flow and the heat transfer about the cross-flow fin-tube heat exchanger in an outdoor unit of a heat pump system has been numerically investigated. Using the general purpose analysis code, FLUENT, the Navier-Stokes equations and the energy equation are solved for the three dimensional computation domain. The flow solution provides the effective permeability and the inertial resistance factor of the heat exchanger if the exchanger were to be approximated by the porous medium. This information is essential in carrying out the global flow field and temperature-field calculation of the heat exchanger unit. `` 99 Fluid Mechanics, Heat Transfer and Combustion Cycle-Resolved Charge Evolution Measurements In A Direct Injected Engine Using Double-Pulse LIF James Smith and Professor Volker Sick smithdj@umich.edu Keywords: Direct-Injected Spark-Ignition; Laser-Induced Fluorescence; Combustion Stability; Stratified Charge Advanced engine concepts such as the Direct-Injected Spark-Ignition (DISI) engine rely on highly accurate spatial and temporal placement of fuel to achieve robust ignition and subsequent combustion. This study utilizes double-pulse Laser-Induced Fluorescence (LIF) to investigate fuel equivalence ratios on a cycle resolved basis inside a firing DISI engine operating in the stratified charge regime. By imaging not only 2-D equivalence ratio fields, but also the evolution of these fields over time, more can be learned of the causes of engine misfire so that preventative measures can be taken. Electrokinetic Pumps for Dynamic Actuation of Cochlear Implants during Surgical Insertion Meng-Ping Chang, Robert J. Bartz, and Professor Hasselbrink mpchang@umich.edu Keywords: electroosmosis, electrokinetic pump, cochlear implants, shape control A key difficulty in using cochlear implants during surgical insertion is that the implants can only reach a certain depth because of imperfect shape match of cochlear and implants. A Bourdon-tube-like design allows for real time hydraulic actuation of the shape of the implants during insertion, but this requires fast-response high pressure/low flow rate integrated micropumps. We are building and characterizing electrokinetic micropumps for hydraulic actuation in this and similar applications. The electrokinetic pump can be built in a variety configuration: such as porous glass frit or nano-channels on a glass substrate. Results show pressures of 7 psi/volt and successful actuation of the cochlear implant backing device using the glass frit pump; characterization of the micropump and challenges for long-term operation of micropumps will also be addressed. `` 100 Fluid Mechanics, Heat Transfer and Combustion Modeling of Porous Filter Permeability via Image-Based Stochastic Reconstruction Fu Zhao and Professor Steven J. Skerlos fzhao@umich.edu The current design of porous filtration system widely used in pollution prevention applications relies heavily on empirical models with parameters calibrated based on time consuming experiments. This research develops a methodology for producing a porescale, 3D computational model of porous filter permeability that is based only on the analysis of 2D images of the filter matrix (e.g., acquired from photography or electron microscopy) and first principles. The computationally reconstructed porous filter model retains statistical details of porosity and its spatial correlations within the filter, and can be used to calculate permeability for either isotropic or 1D anisotropic porous filters. It is shown that the model can predict water flux directly from first principles with deviations from experimental measurements on the order of experimental error, and the methodology yields predictions of permeability that are similar or better than predictions offered by existing filtration models, while not requiring experimentally determined coefficients. Temperature-Dependent Luminescence Quenching in Random Nano Porous Media Xiulin Ruan and Professor Massoud Kaviany xruan@umich.edu The luminescence quenching of a random, crystalline one-dimensional model porous medium doped with rare-earth elements, is analyzed by considering the transport, transition, and interaction of the fundamental energy carriers. The quenching in nano porous media is enhanced compared to a single crystal, due to multiple scattering, enhanced absorption, and low thermal conductivity. The coherent wave treatment is used to calculate the photon absorption, in order to allow for field interference and enhancement. The luminescent and thermal emission is considered as incoherent. The luminescence quenching and nonlinear thermal emission, occurring with increasing irradiation intensity, are predicted. `` 101 Fluid Mechanics, Heat Transfer and Combustion A Fully Integrated CFD and Multi-zone Model with Detailed Chemical Kinetics for the Simulation of HCCI Engines Aristotelis Babajimopoulos and Professor Dennis Assanis ababajim@umich.edu Keywords: HCCI, CFD, Combustion, Chemical Kinetics, Mixing Temperature gradients present in an engine cylinder due to heat transfer to the cylinder walls and composition stratification due to insufficient mixing can have a significant effect on the combustion process in a Homogeneous Charge Compression Ignition (HCCI) engine. Modeling this process is a challenging task, because both mixing and chemistry must be handled in a computationally efficient way. A modeling approach that fully integrates a CFD code (KIVA-3V) with a multi-zone model with detailed chemical kinetics is introduced. At each computational timestep, a multi-zone model provides the KIVA-3V with the necessary energy source terms for each cell, by solving the detailed chemical kinetics for groups of cells (zones) with similar properties. An Experimental Investigation of the Effect of Fuel Concentration on Nonpremixed Jet Flames Tershia Pinder and Arvind Atreya tpinder@engin.umich.edu Keywords: nonpremixed flames, composition oscillations, transient combustion Appropriate mixing of fuel and air is important for efficient combustion and for reducing pollutant formation during combustion. While unsteady techniques have been experimentally examined, most of these studies correspond to flow field fluctuations and not composition fluctuations. In this work, the effect of inlet fuel concentration fluctuations on a nonpremixed jet flame are examined to obtained a better understanding of the mixing and pollutant formation processes. The effects of oscillation frequency and Reynolds number on radiation and species emissions are studied using spectrally and spatially resolved infrared images and temporally and spectrally resolved line-of-sight emission and absorption measurements. `` 102 Fluid Mechanics, Heat Transfer and Combustion Effect of Increase in CO2 Concentration on Radiative Properties of Unsteady Spherical Diffusion Flames in Microgravity Melissa Chernovsky and Professor Arvind Atreya mchernov@umich.edu The objective of this research is to experimentally and theoretically investigate the contribution of CO2 as a diluent in the reaction zone of a gaseous diffusion flame in microgravity. Tests are conducted with ethylene, C2H4, diluted with CO2 and control mixtures of non-reacting diluents. Time-dependent measurements of the flame radius, flame temperature, spectral radiation, and the spatial distribution of soot are obtained. Numerical analysis examines the interaction between flame radiation and chemistry. Experimental work is conducted at the 2.2 second drop tower at the NASA Glenn Research Center. The aim of this research is to improve our fundamental understanding of combustion processes and help develop fire suppression and detection technology for space applications. Transient Spray Cone Angles in Pressure-swirl Injector Sprays Jordan A. Snyder, Ronald O. Grover, Jr., Professor Volker Sick and Professor Dennis Assanis janyder@engin.umich.edu, rgrover@engin.umich.edu Keywords: sprays, pressure-swirl, nozzle fluctuations The transient cone angle of pressure swirl sprays from injectors intended for use in gasoline direct injection engines was measured from 2D Mie scattering images. A variety of injectors with varying nominal cone angle and flow rate were investigated. The general cone angle behavior was found to correlate well qualitatively with the measured fuel line pressure and was affected by the different injector specifications. Experimentally measured modulations in cone angle and injection pressure were forced on a comprehensive spray simulation to understand the sensitivity of pulsating injector boundary conditions on general spray structure. Ignoring the nozzle fluctuations led to a computed spray shape that inadequately replicated the experimental images; hence, demonstrating the importance of quantifying the injector boundary conditions when characterizing a spray using high-fidelity simulation tools. `` 103 Biomechanics Dynamic Modeling of Karate Front Kick Jiro Doke and Professor Arthur D. Kuo jdokeh@umich.edu Keywords: karate kick, biomechanics, dynamic modeling A front kick is one of the most common forms of kick in karate. From observation, the hip and the knee of the kicking leg go through a sequence of flexion and extension phase. However, it is not well known how this coordination of joints relates to the performance of the kick, and whether this is the optimal sequence. A computer simulation model was created to examine the effect of coordination and joint torque activation levels on foot speed at impact. The results showed that the hip is the primary driver for the kick, and the knee contributes more during extension rather than during the initial flexion phase. `` 104 Bio-engineering Optimized Design of a Thoracic Artificial Lung Using Computational Fluid Dynamics Jeongho Kim, MS; Keith Cook, PhD jeonghok@umich.edu Computational fluid dynamics (CFD) was applied to the design of the inlet and outlet of a thoracic artificial lung (TAL). Numerical calculations were performed in a threedimensional geometry. A porous media model was used for the fiber bundle inside the TAL. As an inlet boundary condition, steady, uniform inlet flows (Q) were given between zero to 20 L/min. The outlet boundary was pressure equals zero mmHg. Inlet and outlet diameters of 1/2", 5/8", and 3/4" were used to find a relationship between device pressure drop and inlet/outlet diameter. Results indicate that pressure drop (ΔP) increases quadratically with flow rate; ΔP = 0.42001 Q2 + 0.2134 Q (R2 = 0.99), ΔP = 0.13388 Q2 + 0.22859 Q (R2 = 0.99), and ΔP = 0.05618 Q2 + 0.14044 Q (R2 = 0.99) for 1/2", 5/8", and 3/4" inlets, respectively. Increasing diameter, furthermore, markedly reduces pressure drop. At 4 L/min of flow, pressure drop was 8.06 mmHg, 3.82 mmHg, and 2.23 mmHg for 1/2", 5/8", and 3/4" inlets. Human balancing strategy used by riding bicycle as slow as possible Hogene Kim, Professor James Ashton-Miller hogenek@umich.edu Keywords: Inertial measurement unit, Accelerometer, Angular rate gyro, Loss of control Identifying human control strategy on balancing a bicycle is highly nonlinear control problem. This study will show different human control strategies in initial and adapted period of riding a bicycle. Inertial measurement unit (IMU), which consists of three perpendicular accelerometers and angular rate gyros, was successfully developed and its signals from human upper body and bike, during riding a bicycle as slow as possible, identified different movement characteristics between initial and adapted period. The future study will continue to investigate human control strategy on balancing a bicycle and possible reasons for loss of control. `` 105 Bioengineering- Biomechanics Enhanced Mineralization and Reduced Toughness in the Aging Brtl Mouse Model for Type IV OI K.M. Kozloff, T.E. Uveges, J.C. Marini, S.A. Goldstein kenkoz@umich.edu Keywords: Bone mechanics, osteogenesis imperfecta, genetic mutation Osteogenesis imperfecta (OI) is a connective tissue disorder resulting from mutations in type I collagen. While generally thought of in terms of its pediatric implications, lifespan in patients with normal cardiopulmonary status may be normal. Consequentially, maintenance of bone health later in life is critical to the long-term care of the OI patient. The Brtl mouse model for type IV OI provides a means to investigate long-term effects of a G349C point mutation in one col1a1 allele on whole bone structure-function relationships. This study characterizes the skeletal phenotype of the Brtl mouse at an advanced age of 18 months. `` 106 Solid Mechanics and Materials Analysis of polymer deformation in nanoimprint lithography by using molecular dynamics simulation Ji-Hoon Kang and Professor Kyung-Woong Kim deli@kaist.ac.kr Keywords: Molecular dynamics simulation, nanoimprint lithography, adhesion, polymer deformation In this study, molecular dynamics simulations of nanoimprint lithography in which a stamp with patterns is pressed onto amorphous poly-(methylmethacrylate) (PMMA) surface are performed to study the deformation of polymer. Force fields including bond, angle, torsion, inversion, van der Waals and electrostatic potential are used to describe the intermolecular and intramolecular force of PMMA molecules and stamp. As the simulation results, the mechanism of polymer deformation is investigated by means of inspecting trajectory of particles and molecular configurational properties. The adhesion forces between stamp and polymer are calculated and its effects on the polymer deformation are also studied. Consequently, the simulation results will give us understanding of polymer deformation in nanoimprint lithography and will be utilized for the design of nanoimprint lithography. A study on interfacial delamination in thin film structure by pull test Woosung Choi and Professor Y.Y Earmme woosung@kaist.ac.kr Keywords: bridge thin film, delamination, nanoindenter In recent years, thin films and coatings have been increasingly used in many widely various applications. Although a thorough understanding of mechanical properties and interfacial delamination is desired to ensure the reliability of thin-film adhesion, it was not until the introduction of a fracture mechanics approach that interfacial adhesion was studied extensively and systematically. In this study, the bridge delamination experiment was used to test the mechanical response of freestanding thin film gold specimens with nanoindenter. Analytical constitutive relations are derived here based on membrane theory and are compared with experimental results. In order to compare analytical and experimental result, a two-dimensional geometrically nonlinear FEA is also carried out to simulate the pull-off test, and the energy release rate is obtained. `` 107 Bioengineering A 3D Dual Transducer Ultrasound Technique for the Assessment of Vascular Flow using Contrast Agent Imaging Nelson Chen and Drs. J. Brian Fowlkes, Paul Carson and Gerald LeCarpentier ngchen@umich.edu We are developing a dual-transducer technique that enables rapid three-dimensional vascular flow data collection in a tissue volume. Conventional refill imaging is extended by separating the tasks of contrast clearance and readout, and assigning them to separate ultrasound probes mounted on a computerized translation system. Refill data for the entire volume at a given time point is gathered during each sweep. Multiple sweeps complete the refill curves for the volume. Data is combined to provide a threedimensional vascular flow map. Initial results show strong correlation (r=0.96, p=0.005) between data thus collected and data collected with traditional interval imaging. Stochastic Simulation of Biometal binding to Protein Sensors Munish V. Inamdar, Yun-Bo Yi, Christian Lastoskie, Carol Fierke, Ann Marie Sastry minamdar@umich.edu Keywords: zinc, protein, biometal, transport, intracellular, carbonic anhydrase, diffusion, stochastic simulation Zinc performs crucial catalytic, structural and regulatory roles in the body, though its tight regulation is essential, due to its potential toxicity in the cell. We use direct stochastic modeling to study interactions between zinc ions and carbonic anhydrase (CA) molecules, used as intracellular sensors for zinc. We have developed simulations of local interactions of zinc ions and these high-affinity and selectivity CA sensors. The resulting simulations are capable of extracting association rate, dissociation rate and dissociation constants for CA-zinc reaction in water; this extends significantly the present capability of the traditional diffusion approach in this field. `` 108 Bio-Engineering The effects of low frequency ultrasound on droplets and bubbles Andrea H. Lo, Oliver D. Kripfgans, Paul L. Carson, J. Brian Fowlkes ahlo@umich.edu Ultrasound (US) induced gas bubbles have the potential to be used as a tool for cancer therapy. With the use of US, dodecafluoropentane (DDFP) droplets can be vaporized in tissue and/or in the vasculature to create microbubbles at desired locations. Bubbles driven by low frequency US, which is less susceptible to attenuation, can be useful as they can either oscillate at their resonant frequency to create mechanical damage in the surrounding area or scatter energy to increase local thermal effects. By using tissue mimicking polyacrylamide gels, the effects of low frequency US on droplets and bubbles are investigated. Multi-image registration and image atlas construction using entropic graph based mutual information estimation Neemuchwala HF, Hero AO, Park HJ, Carson PL, Meyer CR. hneemuch@umich.edu Keywords: image registration, atlas, entropic graphs, mutual information We present a new method for multi-image registration and atlas construction using entropy methods. Multidimensional estimates of Renyi α-entropy and Renyi α-mutual information are derived using entropic graphs such as nearest neighbor graphs. Thus, we overcome the computational and statistical drawbacks of pixel histograms for multidimensional entropy estimation. Further, we use wavelet feature vectors as opposed to conventional scalar pixel features. Graph methods allow us to simultaneously register or construct atlas images for large patients databases, a significant improvement over current capabilities of histogram methods. A clustering approach is used to estimate depth of images in the databases to provide an initial estimate of the atlas image. `` 109 Tissue Regeneration and Cellular Biotechnology ELECTROKINETIC PHENOMENA DURING ELECTROELUTION FROM CLINICAL SAMPLING STRIPS Sun Min Kim and E. F. Hasselbrink, Jr. sunmk@umich.edu Keywords: Electroelution, Macro-to-micro interface, Unsteady electrokinetics In this research, a micro device for eluting protei used for oral fluid sample collection was fabricated using PDMS (Poly dimethylsiloxane) polymer. PDMS polymer has been used to fabricate micro systems due to easy and fast fabrication, low cost, and compatibility with bio materials. BSA (Bovine Serum Albumin) and OVA (Ovalbumin) were labelled with FITC (Fluorescein isothiocyanate) dye for detecting movements using a fluorescent microscope. About 50% of the initial concentration of BSA and OVA was eluted by the ~20V/cm electric field strength. During the electroelution process, unsteady electrokinetic phenomena by the pressure driven flow and the pH change of the reservoirs were observed. This electroelution device can be integrated with a protein concentrator and a separation column to analyze proteins. This integrated device will be fabricated in near future. Inverted Colloidal Crystals as a Tissue Engineering Scaffold Jungwoo Lee, Nicholas Kotov jungwoo@umich.edu Keywords: Inverted colloidal crystals, Scaffolds, Tissue engineering An inverted colloidal crystal which has a well interconnected porous geometry provided ideal structure for the tissue engineering scaffolds. Hydrogels are commonly used as a biomaterial for scaffolds because of their biocompatible and biodegradable characteristics. The aim of this study was to address the hypothesis that inverted colloidal crystals consisted with hydrogels enhanced three dimensional cell-growth. Highly ordered colloidal crystals with 100μm size polystyrene beads were prepared by the modification of a conventional method. Poly (acryl-amid) hydrogels solution was used as a scaffolding material. Good geometry of the scaffold improved mass transfer inside of structure and promoted three dimensional formations of tissue. `` 110 Bioengineering Microfluidic Immunoassays using a Braille Display for Computer-controlled Fluid Actuation Yoko Kamotani, Wei Gu, Nobuyuki Futai, Shuichi Takayama ykamotan@umich.edu Keywords: Microfluidics, immunoassays, microfabrication Microchannel immunoassays overcome the limitations of conventional assays with enhanced reaction efficiency, simplified procedures, and reduced consumption of reagents. We have developed a self-contained, automated microfluidic immunoassay system. This system is fabricated with elastomeric poly(dimethylsiloxane) (PDMS) and liquid flow is controlled using mechanical actuators provided by a commercially available, refreshable Braille display. A combination of valves and independent pumps actuated by an array of 160 Braille pins allow for simultaneous analysis of multiple antigen samples. A fully automated immunoassay system will be beneficial to a variety of fields including cellular biology and biochemical detection. Endothelial Cell Culture Under Computer-controlled Flow in Microfluidic Channels Jonathan W. Song, Wei Gu, Nobuyaki Futai, Kristy A. Warner, Jacques E. Nor, and Shuichi Takayama songjon@umich.edu Keywords: endothelial cells, microfabrication, cell culture, shear stress We propose to study the effects of shear stress on endothelial cell (EC) alignment and elongation within a microcirculatory mammalian cell culture system. For this purpose, we have designed a microfluidic cell shearing chamber fabricated from poly(dimethylsiloxane) (PDMS) that is computer-controlled through a refreshable Braille display. The piezoelectric pins of the Braille display function as a network of microfluidic pumps and valves that actuate fluid in a pulsatile nature. The system demonstrates significant versatility in shear stress levels and rate of delivery that can be recreated in evaluating the physiological and biological effects associated with shear stress in ECs. `` 111 Biotechnology, Muscle Mechanics Effect of contraction-induced injury in young mice lacking superoxide dismutase or glutathione peroxidase genes Rainer Ng and Professor John A. Faulkner nrn@umich.edu Contraction-induced injury produces an initial mechanical disruption in the muscle followed by a secondary injury several days later. Compared with untreated mice, mice treated with a large molecular weight free radical scavenger show a 50% reduction in force deficit. The decrease in the force deficit, along with the large mass of the scavenger, are consistent with a secondary injury caused by ROS located in the extracellular matrix. We tested the hypothesis that mice lacking intracellular antioxidants such as superoxide dismutase and glutathione peroxidase will not respond differently from wild type mice to contraction-induced injury. Comparison of force deficits and injured muscle fiber counts on wild type and knockout mice will clarify the response to contraction-induced injury. `` 112 Bio-Engineering Nano-tubular structured conducting polymers for neural prostheses applications Mohammad Reza Abidian and Professor David C. Martin mabidian@umich.edu Keywords: prostheses Nanofibers, electrospinning, electrochemical polymerization, neural The ability of neural electrodes to record high signals over extended periods of time remains the significant problems. The engineering of bioactive electrode coatings has been investigated for its potential to promote in-growth of neural tissue, reduce shear stress, and enhance signal transport from electrons to ions at the electrode-host interface. We have found that films of electrospun nanofibers can be deposited on the surface of these devices, followed by electrochemical polymerization of conducting polymers such as polypyrrole or poly(3,4-ethylenedioxythiophene) in the presence of counterions. After polymerization, nanofibers templates can be dissolved, leaving tiny channels, pores and nano tubular structures in the conducting polymers. This morphology facilitates efficient signal transport and communication with the neural tissue. The electrical properties of the polymer functionalized probes were examined with impedance spectroscopy and cyclic voltametry. The impedance spectroscopy revealed that the impedance of gold electrode significantly decreased from 800 kΩ to 8 kΩ. The surface morphology of the coated electrodes was assessed by optical microscopy and scanning electron microscopy. Scanning electron microscopy showed the nano tubular structure of conducting polymers on the electrode sites. `` 113 `` `` ``