Internet Activity: Cell Cycle and Cancer
Name___________________________________________________Period___________Date_____________
Directions: go to the following websites/links, and look at the animations on the cell cycle and cancer, and read the
information. Follow the animations as closely as possible and pay attention to the stages of each. Follow the
directions below, and answer any questions indicated below. You may change the order for visiting each website if
you would like. Once you complete each section, ask you teacher for a stamp. Each stamp is worth ten points.
Site http://www.wisc-online.com/objects/ViewObject.aspx?ID=AP13604. Read the introductions and follow
the animation. Answer the questions below. Click the next button at the bottom of the page to advance to the
next page.
1. What tells the cell whether or not to proceed to the next path?
2. What are the three major phases of the cell cycle?
3. What is happening during the G1 phase of the cell cycle?
4. What makes the G1 such a crucial point in the cell cycle?
5. What makes the G0 phase a critical point in the cell cycle?
6. Describe one example besides the one in the animation, of a cell entering the G0 phase of the cell cycle?
7. What is apoptosis?
8. What happens to cells selected for apoptosis? What cellular process is used for this process to occur?
9. What occurs during the S phase?
10. List two things that occur during the G2 phase so the cell can enter the M phase(mitosis)?
1.
2.
STOP!!! Once you complete this section, ask your teacher for a stamp.
11.On the picture below, label the phases of the cell cycle. Use the words interphase, G1, G0, S, G2 and M phase.
12. Click on the link below to examine some chemicals involved in the regulation of the cell cycle. Create a graphic
organizer in the space below comparing the different chemicals and their functions.
http://www.biology.arizona.edu/cell_bio/tutorials/cell_cycle/cells2.html
13. Perform a google search of Li Fraumeni syndrome, and in the space below give brief summary of the disease
and its connection to p53 gene.
STOP!!! Once you complete this section, ask your teacher for a stamp.
Click on the link below or paste it into the search bar and complete the quiz on cell cycle and mitosis. Write the letter
and word of the correct answer on the lines below,
http://www.biology.arizona.edu/cell_bio/tutorials/cell_cycle/problems.html
1. The stage of the cell cycle where each chromosome is composed of two chromatids in preparation for
mitosis.
Answer:_____________________________________________________________________________
2. The class of enzymes that are involved in triggering events in the cell cycle are called:
Answer:_____________________________________________________________________________
3. Which sequence of the cell cycle is common to eukaryotes?
Answer:_____________________________________________________________________________
4. The stage of the cell cycle where the cell is preparing to begin DNA replication is called:
Answer:_____________________________________________________________________________
5. The proteins which complex with DNA producing the "beads on a string" or nucleosomes are called:
Answer:_____________________________________________________________________________
6. Which of the following features of cell division are very different for animal and plant cells?
Answer:_____________________________________________________________________________
7. Prior to cell division, each chromosome replicates or duplicates its genetic material. The products are
connected by a centromere and are called:
Answer:_____________________________________________________________________________
8. The first stage of mitosis when chromosomes start becoming visible in the microscope is called:
Answer:_____________________________________________________________________________
9. The sputum (fluid coughed up from the lungs) of many smokers contain cells with mutations (errors) in the
genes for p53. The smoking induced mutations appear to be an early signal showing that cancer of the lungs
will follow. What is the likely relationship between early p53 mutation and the development of lung cancer?
Answer:_____________________________________________________________________________
10. Which of the following statements is NOT true of mitosis?
Answer:_____________________________________________________________________________
11. Cytokinesis in a plant cell is characterized by:
Answer:_____________________________________________________________________________
STOP!!! Once you complete this section, ask your teacher for a stamp.