StatinGuard® StatinGuard ® is a nutritional supplement designed to help maintain healthful Coenzyme Q10 levels and promote cardiovascular health.* Coenzyme Q10 (CoQ10) is produced by the human body and is necessary for the basic functioning of cells. CoQ10 levels are reported to decrease with age and to be low in patients with some chronic diseases such as heart conditions, muscular dystrophies, Parkinson’s disease, cancer, diabetes, and HIV / AIDS. Some prescription drugs, including the statins, may also lower CoQ10 levels. SUPPLEMENT FACTS Serving Size: 1 Tablet Statins include well-known cholesterol-lowering drugs such as Lipitor, Zocor, Servings per Container:90 Mevacor, Pravachol, Crestor, and others. Since CoQ10 shares a common AMOUNT PER SERVING %DV synthetic pathway with cholesterol, drugs that inhibit cholesterol synthesis, like Vitamin E (as d-Alpha Tocopheryl Acetate the statins, can reduce CoQ10 levels, which may cause side effects like muscle and Natural Mixed Tocopherols) 150 IU 500% pain and weakness. Maintaining healthful levels of coenzyme Q10 is important L-carnitine (as L-carnitine L-tartrate) 125 mg ** for heart health.* L-carnitine (as N-acetyl-L-Carnitine) 125 mg ** CoQ10 functions as an electron carrier in the mitochondrial respiratory chain as well as serves as an important intracellular antioxidant. CoQ10 is found throughout the body with the highest concentration in the cells of organs that require large amounts of energy such as the heart and kidneys. Alpha Lipoic Acid Coenzyme Q10 50 mg 100 mg ** Daily Value not established OTHER INGREDIENTS: Microcrystalline Cellulose, Silicon Dioxide, Croscarmellose Sodium, Magnesium Stearate, Stearic Acid, Hydroxypropyl Methylcellulose, Triacetin Food Grade, Talc, Riboflavin, Titanium Dioxide. L-carnitine and alpha lipoic acid are included in StatinGuard® because of their uniquely beneficial interplay with CoQ10. L-carnitine is an amino acid-derived compound necessary for transport of long chain fatty acids as fuel into the mitochondria. Alpha lipoic acid is a highly effective nutritional antioxidant in bolstering cellular and tissue levels of glutathione.* *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. www.vitalremedymd.com ** ** Cholesterol levels aside, there’s more we need to know. Lipids Lipids (better known as fats) comprise a diverse group of substances that represents an essential component of every cell in our body, and an unavoidable and necessary part of a healthful diet. Our real goal is not to shun fats, but to consume the right fats in the right amounts. On one end of the spectrum are the healthful omega-3 fatty acids; on the other end are the terrible trans fats. Somewhere in between we have saturated, monounsaturated, and other polyunsaturated fats. Their relative significance comes into play in a variety of ways, one being how they impact our HDL and LDL. Some raise “bad” LDL cholesterol, and lower “good” HDL cholesterol. Even worse, some fats increase the number of small LDL cholesterol particles in the bloodstream. This is important because people with normal total cholesterol levels who have excess small dense LDL particles are at high cardiovascular risk. Lipoproteins Let me explain. Oil and water don’t mix well in salad dressing and the same holds true in our bodies. Blood, which is like water, won’t mix well with cholesterol, a fat. And so our bodies have produced carriers for fats called lipoproteins. LDL stands for Low Density Lipoprotein and HDL for High Density Lipoprotein. Conventional cholesterol blood tests quantify the amount of cholesterol contained in the entire range of LDL or HDL particles in our body. There is no consideration given to the important fact that among individuals there is huge variation in the characteristics of these particles. Beyond knowing one’s LDL cholesterol level, knowing the number and size of those LDL particles is essential to understanding an individual’s unique risk from lipid abnormalities. The greater the number and the smaller the size of the LDL particles in a given patient, the more likely that person is to develop heart disease. Advanced Lipid Testing Comparison of conventional cholesterol testing with more advanced lipid profile blood testing readily demonstrates the issues. A common scenario is the patient who has a “normal” LDL on conventional lipid testing, but a more advanced lipoprotein analysis reveals an overabundance of small LDL particles. The conventional lipid test would tell the doctor, no need to worry. On the contrary, this particular patient does need intensive therapy; she’s at great cardiovascular risk and requires treatment. On the other side of the coin is the patient who has high LDL readings on conventional lipid testing because his LDL particles are extraordinarily large, but does not need the same degree of intensive lipid lowering because his total number of LDL particles may in fact be quite low. Her risk of developing atherosclerotic heart disease as a consequence of lipid abnormalities is not nearly as great as conventional tests implied and for him the risk of medication may not be justified.. www.fpim.org