Organelles This video provides the content for your “Basics” class notes. It moves quickly, so pause it often while you write. Bring your notes to class. Cell Organelles Before we begin: Gene to protein Transcription RNA processing Translation Nucleus 1. Contains DNA, nucleolus 2. Nuclear envelope 3. Nuclear pores 4. Nuclear import or export tags Chromatin Nucleolus Endoplasmic reticulum Smooth ER 1. No ribosomes 2. Factory: 3. Pocket: Rough ER 1. Ribosomes bind and unbind 2. Factory: 3. Pocket: Ribosomes Ribosomes Free Bound Golgi apparatus Cisterna Cis face Trans face Golgi apparatus The Endomembrane System Lysosomes Lysosomes Proteins are found in different locations Enzymes Microtubules Motor proteins Transporters Receptors Antibodies Insulin Collagen The signal peptide Nucleus mRNA mRNA polypeptide Signal peptide Signal recognition particle (SRP) The signal recognition particle Rough ER Translation into the rough ER Different Paths secreted rough ER Golgi plasma membrane membrane rough ER cytosolic cytoplasm Golgi plasma membrane Prep for Basics Quiz Can you do the following? • Label all major organelles in a figure of a cell • Describe the features and functions of the nucleus, endoplasmic reticulum, smooth ER, rough ER, Golgi, and lysosomes • Describe the structure, locations and function of ribosomes • List difference between free and bound ribosomes