Notes

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Organelles
This video provides the content for your “Basics” class notes.
It moves quickly, so pause it often while you write.
Bring your notes to class.
Cell Organelles
Before we begin: Gene to protein
Transcription
RNA processing
Translation
Nucleus
1. Contains DNA, nucleolus
2. Nuclear envelope
3. Nuclear pores
4. Nuclear import or export tags
Chromatin
Nucleolus
Endoplasmic reticulum
Smooth ER
1. No ribosomes
2. Factory:
3. Pocket:
Rough ER
1. Ribosomes bind and unbind
2. Factory:
3. Pocket:
Ribosomes
Ribosomes
Free
Bound
Golgi apparatus
Cisterna
Cis face
Trans face
Golgi apparatus
The Endomembrane System
Lysosomes
Lysosomes
Proteins are found in different locations
Enzymes
Microtubules
Motor proteins
Transporters
Receptors
Antibodies
Insulin
Collagen
The signal peptide
Nucleus
mRNA
mRNA
polypeptide
Signal peptide
Signal recognition particle (SRP)
The signal recognition particle
Rough
ER
Translation into the rough ER
Different Paths
secreted
rough ER
Golgi
plasma membrane
membrane
rough ER
cytosolic
cytoplasm
Golgi
plasma membrane
Prep for Basics Quiz
Can you do the following?
• Label all major organelles in a figure of a cell
• Describe the features and functions of the nucleus,
endoplasmic reticulum, smooth ER, rough ER, Golgi,
and lysosomes
• Describe the structure, locations and function of
ribosomes
• List difference between free and bound ribosomes
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